N+/Si replacement as a tool for probing the pharmacophore of allosteric modulators of muscarinic M2 receptors: Synthesis, allosteric potency, and positive cooperativity of silicon-based W84 derivatives

Organometallics

Volumn 21, Issue 5, 2002, Pages 803-811

  Daiss, Jürgen O ^a   Duda Johner, Seraina ^b   Burschka, Christian ^a   Holzgrabe, Ulrike ^a   Mohr, Klaus ^b   Tacke, Reinhold ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; DISSOCIATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SILICON; SINGLE CRYSTALS; SYNTHESIS (CHEMICAL); X RAY DIFFRACTION ANALYSIS;

ALLOSTERIC AGENTS;

ORGANOMETALLICS;

EID: 0000742452     PISSN: 02767333     EISSN: None     Source Type: Journal    
DOI: 10.1021/om010847j     Document Type: Article

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