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Journal of the American Chemical Society

Volumn 125, Issue 25, 2003, Pages 7696-7703

Fluorine-NMR experiments for high-throughput screening: Theoretical aspects, practical considerations, and range of applicability

(5) Dalvit, Claudio a Fagerness, Paul E b Hadden, Daneen T A c Sarver, Ronald W b Stockman, Brian J c

a Chemistry Department (Italy)

b Pharmacia (Italy)

c Pharmacia (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOTROPY; DETERGENTS; MIXTURES; NUCLEAR MAGNETIC RESONANCE; PROTEINS; PROTONS; SOLUBILITY; SOLVENTS;

BINDING CONSTANTS;

FLUORINE;

BUFFER; CHEMICAL COMPOUND; DETERGENT; FLUORINE; SERUM ALBUMIN; SOLVENT;

ANISOTROPY; ARTICLE; AUTOANALYSIS; BINDING AFFINITY; CHEMICAL ANALYSIS; LIGAND BINDING; MEASUREMENT; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; SCREENING TEST; SOLUBILITY; TECHNIQUE;

FLUORINE; HUMANS; LIGANDS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SENSITIVITY AND SPECIFICITY; SERUM ALBUMIN; TITRIMETRY;

EID: 0038207989 PISSN: 00027863 EISSN: None Source Type: Journal
DOI: 10.1021/ja034646d Document Type: Article

Times cited : (219)

References (58)

1
- 0014721567
- (a) Roberts, G. C. K.; Jardetzky, O. Adv. Protein Chem. 1970, 24, 447-545.
- (1970) Adv. Protein Chem. , vol.24 , pp. 447-545
- Roberts, G.C.K.¹ Jardetzky, O.²

2
- 0038221393
- (b) Sheard, B.; Bradbury, E. M. Prog. Biophys. Mol. Biol. 1970, 20, 187-246.
- (1970) Prog. Biophys. Mol. Biol. , vol.20 , pp. 187-246
- Sheard, B.¹ Bradbury, E.M.²

3
- 0029836953
- (a) Shuker, S. B.; Hajduk, P. J.; Meadows R. P.; Fesik, S. W. Science 1996, 274, 1531-1534.
- (1996) Science , vol.274 , pp. 1531-1534
- Shuker, S.B.¹ Hajduk, P.J.² Meadows, R.P.³ Fesik, S.W.⁴

4
- 16944365890
- (b) Hajduk, P. J.; Sheppard, D. G.; Nettesheim, D. G.; Olejniczak, E. T.; Shuker, S. B.; Meadows, R. P.; Steinman, D. H.; Carrera, G. M., Jr.; Marcotte, P. M.; Severin, J.; Walter, K.; Smith, H.; Gubbins, E.; Simmer, R.; Holzman, T. F.; Morgan, D. W.; Davidsen, S. K.; Summers, J. B.; Fesik, S. W. J. Am. Chem. Soc. 1997, 119, 5818-5827.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 5818-5827
- Hajduk, P.J.¹ Sheppard, D.G.² Nettesheim, D.G.³ Olejniczak, E.T.⁴ Shuker, S.B.⁵ Meadows, R.P.⁶ Steinman, D.H.⁷ Carrera G.M., Jr.⁸ Marcotte, P.M.⁹ Severin, J.¹⁰ Walter, K.¹¹ Smith, H.¹² Gubbins, E.¹³ Simmer, R.¹⁴ Holzman, T.F.¹⁵ Morgan, D.W.¹⁶ Davidsen, S.K.¹⁷ Summers, J.B.¹⁸ Fesik, S.W.¹⁹

5
- 0001307841
- (a) Stockman, B. J. Prog. Nucl. Magn. Reson. Spec. 1998, 33, 109-151.
- (1998) Prog. Nucl. Magn. Reson. Spec. , vol.33 , pp. 109-151
- Stockman, B.J.¹

6
- 0034923365
- (b) Stockman, B. J.; Farley, K. A.; Angwin, D. T. Methods Enzymol. 2001, 338, 230-246.
- (2001) Methods Enzymol. , vol.338 , pp. 230-246
- Stockman, B.J.¹ Farley, K.A.² Angwin, D.T.³

7
- 0033341062
- Hajduk, P. J.; Meadows, R. P., Fesik, S. W. Q. Rev. Biophys. 1999, 32, 211-240.
- (1999) Q. Rev. Biophys. , vol.32 , pp. 211-240
- Hajduk, P.J.¹ Meadows, R.P.² Fesik, S.W.³

8
- 0032900490
- (a) Moore, J. M. Curr. Opin. Biotechnol. 1999, 10, 54-58.
- (1999) Curr. Opin. Biotechnol. , vol.10 , pp. 54-58
- Moore, J.M.¹

9
- 0034923647
- (b) Peng, J. W.; Lepre, C. A.; Fejzo, J.; Abdul-Manan N.; Moore, J. M. Methods Enzymol. 2001, 338, 202-230.
- (2001) Methods Enzymol. , vol.338 , pp. 202-230
- Peng, J.W.¹ Lepre, C.A.² Fejzo, J.³ Abdul-Manan, N.⁴ Moore, J.M.⁵

10
- 0038221392
- Diercks, T.; Coles, M.; Kessler, H. Curr. Opin. Chem. Biol. 2001, 4, 479-492.
- (2001) Curr. Opin. Chem. Biol. , vol.4 , pp. 479-492
- Diercks, T.¹ Coles, M.² Kessler, H.³

11
- 0036490372
- Pellecchia, M.; Sem, D. S.; Wüthrich, K. Nat. Rev. 2002, 1, 211-219.
- (2002) Nat. Rev. , vol.1 , pp. 211-219
- Pellecchia, M.¹ Sem, D.S.² Wüthrich, K.³

12
- 0037088994
- Van Dongen, M.; Weigelt, J.; Uppenberg, J.; Schultz, J.; Wikström, M. Drug Discovety Today 2002, 7, 471-478.
- (2002) Drug Discovety Today , vol.7 , pp. 471-478
- Van Dongen, M.¹ Weigelt, J.² Uppenberg, J.³ Schultz, J.⁴ Wikström, M.⁵

13
- 0036653390
- Wyss, D. F.; McCoy, M. A.; Senior, M. M. Curr. Opin. Drug Discovery Dev. 2002, 5, 630-647.
- (2002) Curr. Opin. Drug Discovery Dev. , vol.5 , pp. 630-647
- Wyss, D.F.¹ McCoy, M.A.² Senior, M.M.³

14
- 0037010533
- Stockman, B. J.; Dalvit C. Prog. Nucl. Magn. Res. Spec. 2002, 41, 187-231.
- (2002) Prog. Nucl. Magn. Res. Spec. , vol.41 , pp. 187-231
- Stockman, B.J.¹ Dalvit, C.²

15
- 0030917461
- (a) Meyer, B.; Weimar, T.; Peters, T. Eur. J. Biochem. 1997, 246, 705-709.
- (1997) Eur. J. Biochem. , vol.246 , pp. 705-709
- Meyer, B.¹ Weimar, T.² Peters, T.³

16
- 0033555207
- (b) Henrichsen, D.; Ernst, B.; Magnani, J. L.; Wang, W.-T.; Meyer, B.; Peters, T. Angew. Chem., Int. Ed. 1999, 38, 98-102.
- (1999) Angew. Chem., Int. Ed. , vol.38 , pp. 98-102
- Henrichsen, D.¹ Ernst, B.² Magnani, J.L.³ Wang, W.-T.⁴ Meyer, B.⁵ Peters, T.⁶

17
- 0001174635
- Lin, M.; Shapiro, M. J.; Wareing, J. R. J. Am. Chem. Soc. 1997, 119, 5249-5250.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 5249-5250
- Lin, M.¹ Shapiro, M.J.² Wareing, J.R.³

18
- 0031576702
- Hajduk, P. J.; Olejniczak E. T.; Fesik, S. W. J. Am. Chem. Soc. 1997, 119, 12257-12261.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 12257-12261
- Hajduk, P.J.¹ Olejniczak, E.T.² Fesik, S.W.³

19
- 0032494393
- (a) Chen, A.; Shapiro, M. J. J. Am. Chem. Soc. 1998, 120, 10258-10259.
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 10258-10259
- Chen, A.¹ Shapiro, M.J.²

20
- 0033963395
- (b) Chen, A.; Shapiro, M. J. J. Am. Chem. Soc. 2000, 122, 414-415.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 414-415
- Chen, A.¹ Shapiro, M.J.²

21
- 0033553844
- (a) Mayer, M.; Meyer, B. Angew. Chem., Int. Ed. 1999, 38, 1784-1788.
- (1999) Angew. Chem., Int. Ed. , vol.38 , pp. 1784-1788
- Mayer, M.¹ Meyer, B.²

22
- 0033538283
- (b) Klein, J.; Meinecke, R.; Mayer, M.; Meyer, B. J. Am. Chem. Soc. 1999, 121, 5336-5337.
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 5336-5337
- Klein, J.¹ Meinecke, R.² Mayer, M.³ Meyer, B.⁴

23
- 0034823890
- (c) Mayer, M.; Meyer, B. J. Am. Chem. Soc. 2001, 123, 6108-6117.
- (2001) J. Am. Chem. Soc. , vol.123 , pp. 6108-6117
- Mayer, M.¹ Meyer, B.²

24
- 0034596286
- (a) Jahnke, W.; Perez, L. B.; Paris, C. G.; Strauss, A.; Fendrich, G.; Nalin, C. M. J. Am. Chem. Soc. 2000, 122, 7394-7395.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 7394-7395
- Jahnke, W.¹ Perez, L.B.² Paris, C.G.³ Strauss, A.⁴ Fendrich, G.⁵ Nalin, C.M.⁶

25
- 0034822661
- (b) Jahnke, W.; Rüdisser, S.; Zurini, M. J. Am. Chem. Soc. 2001, 123, 3149-3150.
- (2001) J. Am. Chem. Soc. , vol.123 , pp. 3149-3150
- Jahnke, W.¹ Rüdisser, S.² Zurini, M.³

26
- 0033789206
- (a) Dalvit, C.; Pevarello, P.; Tatò, M.; Veronesi, M.; Vulpetti, A.; Sundström, M. J. Biomol. NMR 2000, 18, 65-68.
- (2000) J. Biomol. NMR , vol.18 , pp. 65-68
- Dalvit, C.¹ Pevarello, P.² Tatò, M.³ Veronesi, M.⁴ Vulpetti, A.⁵ Sundström, M.⁶

27
- 0035692794
- (b) Dalvit, C.; Fogliatto, G. P.; Stewart, A.; Veronesi, M.; Stockman, B. J. Biomol. NMR 2001, 21, 349-359.
- (2001) J. Biomol. NMR , vol.21 , pp. 349-359
- Dalvit, C.¹ Fogliatto, G.P.² Stewart, A.³ Veronesi, M.⁴ Stockman, B.⁵

28
- 0033213957
- (a) Fejzo, J.; Lepre, C. A.; Peng, J. W.; Bemis, G. W.; Ajay, Murcko, M. A.; Moore, J. M. Chem. Biol. 1999, 6, 755-769.
- (1999) Chem. Biol. , vol.6 , pp. 755-769
- Fejzo, J.¹ Lepre, C.A.² Peng, J.W.³ Bemis, G.W.⁴ Ajay Murcko, M.A.⁵ Moore, J.M.⁶

29
- 0036892232
- (b) Lepre C. A.; Peng, J.; Fejzo, J.; Abdul-Manan, N.; Pocas, J.; Jacobs, M.; Xie, X.; Moore, J. M. Comb. Chem., HTS 2002, 5, 583-590.
- (2002) Comb. Chem., HTS , vol.5 , pp. 583-590
- Lepre, C.A.¹ Peng, J.² Fejzo, J.³ Abdul-Manan, N.⁴ Pocas, J.⁵ Jacobs, M.⁶ Xie, X.⁷ Moore, J.M.⁸

30
- 0033168872
- (a) Hajduk, P. J.; Gerfin, T.; Böhlen J.-M.; Häberli, M.; Marek, D.; Fesik, S. W. J. Med. Chem. 1999, 42, 2315-2317.
- (1999) J. Med. Chem. , vol.42 , pp. 2315-2317
- Hajduk, P.J.¹ Gerfin, T.² Böhlen, J.-M.³ Häberli, M.⁴ Marek, D.⁵ Fesik, S.W.⁶

31
- 0036892171
- (b) Hajduk, P. J.; Burns, D. J. Comb. Chem., High Throughput Screening 2002, 5, 613-621.
- (2002) Comb. Chem., High Throughput Screening , vol.5 , pp. 613-621
- Hajduk, P.J.¹ Burns, D.J.²

32
- 0036892202
- (c) Huth, J. R.; Sun, C. Comb. Chem., High Throughput Screening 2002, 5, 631-643.
- (2002) Comb. Chem., High Throughput Screening , vol.5 , pp. 631-643
- Huth, J.R.¹ Sun, C.²

33
- 0037139612
- (a) Weigelt, J.; Van Dongen, M. J. P.; Uppenberg, J.; Schultz, J.; Wikström, M. J. Am. Chem. Soc. 2002, 124, 2446-2447.
- (2002) J. Am. Chem. Soc. , vol.124 , pp. 2446-2447
- Weigelt, J.¹ Van Dongen, M.J.P.² Uppenberg, J.³ Schultz, J.⁴ Wikström, M.⁵

34
- 0037048588
- (b) Van Dongen, M. J. P.; Uppenberg, J.; Svensson, S.; Lundback, T.; Akerud, T.; Wikström, M.; Schultz, J. J. Am. Chem. Soc. 2002, 124, 11874-11880.
- (2002) J. Am. Chem. Soc. , vol.124 , pp. 11874-11880
- Van Dongen, M.J.P.¹ Uppenberg, J.² Svensson, S.³ Lundback, T.⁴ Akerud, T.⁵ Wikström, M.⁶ Schultz, J.⁷

35
- 0036892960
- Weigelt, J.; Wikström, M.; Schultz, J.; Van Dongen, M. J. P. Comb. Chem., High Throughput Screening 2002, 5, 623-630.
- (2002) Comb. Chem., High Throughput Screening , vol.5 , pp. 623-630
- Weigelt, J.¹ Wikström, M.² Schultz, J.³ Van Dongen, M.J.P.⁴

36
- 0036175914
- Pellecchia, M.; Meininger, D.; Dong, Q.; Chang, E.; Jack, R.; Sem, D. S. J. Biomol. NMR 2002, 22, 165-173.
- (2002) J. Biomol. NMR , vol.22 , pp. 165-173
- Pellecchia, M.¹ Meininger, D.² Dong, Q.³ Chang, E.⁴ Jack, R.⁵ Sem, D.S.⁶

37
- 0037073160
- (a) Mayer, M.; James, T. L. J. Am. Chem. Soc. 2002, 124, 13376-13377.
- (2002) J. Am. Chem. Soc. , vol.124 , pp. 13376-13377
- Mayer, M.¹ James, T.L.²

38
- 0037425531
- (b) Bernie, A. J.; Moser, R.; Bauml, E.; Blaas, D.; Peters, T. J. Am. Chem. Soc. 2003, 125, 14-15.
- (2003) J. Am. Chem. Soc. , vol.125 , pp. 14-15
- Bernie, A.J.¹ Moser, R.² Bauml, E.³ Blaas, D.⁴ Peters, T.⁵

39
- 0037030693
- Dalvit, C.; Fasolini, M.; Flocco, M.; Knapp, S.; Pevarello, P.; Veronesi, M. J. Med. Chem. 2002, 45, 2610-2614.
- (2002) J. Med. Chem. , vol.45 , pp. 2610-2614
- Dalvit, C.¹ Fasolini, M.² Flocco, M.³ Knapp, S.⁴ Pevarello, P.⁵ Veronesi, M.⁶

40
- 0037014686
- (a) Dalvit, C.; Flocco, M.; Knapp, S.; Mostardini, M.; Perego, R.; Stockman, B. J.; Veronesi, M.; Varasi, M. J. Am. Chem. Soc. 2002, 124, 7702-7709.
- (2002) J. Am. Chem. Soc. , vol.124 , pp. 7702-7709
- Dalvit, C.¹ Flocco, M.² Knapp, S.³ Mostardini, M.⁴ Perego, R.⁵ Stockman, B.J.⁶ Veronesi, M.⁷ Varasi, M.⁸

41
- 0036892168
- (b) Dalvit, C.; Flocco, M.; Stockman, B. J.; Veronesi, M. Comb. Chem., High Throughput Screening 2002, 5, 645-650.
- (2002) Comb. Chem., High Throughput Screening , vol.5 , pp. 645-650
- Dalvit, C.¹ Flocco, M.² Stockman, B.J.³ Veronesi, M.⁴

42
- 0037119648
- Jahnke, W.; Floersheim, P.; Ostermeier, C.; Zhang, X.; Hemmig, R.; Hurth, K.; Uzunov, D. P. Angew. Chem., Int. Ed. 2002, 41, 3420-3423.
- (2002) Angew. Chem., Int. Ed. , vol.41 , pp. 3420-3423
- Jahnke, W.¹ Floersheim, P.² Ostermeier, C.³ Zhang, X.⁴ Hemmig, R.⁵ Hurth, K.⁶ Uzunov, D.P.⁷

43
- 0037119713
- Siriwardena, A. H.; Tian, F.; Noble, S.; Prestegard, J. H. Angew. Chem., Int. Ed. 2002, 41, 3454-3457.
- (2002) Angew. Chem., Int. Ed. , vol.41 , pp. 3454-3457
- Siriwardena, A.H.¹ Tian, F.² Noble, S.³ Prestegard, J.H.⁴

44
- 0036893645
- Dalvit, C.; Flocco, M.; Veronesi, M.; Stockman, B. J. Comb. Chem., High Throughput Screening 2002, 5, 605-611.
- (2002) Comb. Chem., High Throughput Screening , vol.5 , pp. 605-611
- Dalvit, C.¹ Flocco, M.² Veronesi, M.³ Stockman, B.J.⁴

45
- 0016697706
- (a) Hull, W. E.; Sykes, B. D. J. Mol. Biol. 1975, 98, 121-153.
- (1975) J. Mol. Biol. , vol.98 , pp. 121-153
- Hull, W.E.¹ Sykes, B.D.²

46
- 0024850562
- (b) Gerig, J. T. Methods Enzymol. 1989, 177, 3-23.
- (1989) Methods Enzymol. , vol.177 , pp. 3-23
- Gerig, J.T.¹

47
- 0000648758
- (c) Gerig, J. T. Prog. NMR Spectrosc. 1994, 26, 293-370.
- (1994) Prog. NMR Spectrosc. , vol.26 , pp. 293-370
- Gerig, J.T.¹

48
- 0003654540
- John Wiley & Sons: Chichester
- Canet, D. Nuclear Magnetic Resonance Concepts and Methods; John Wiley & Sons: Chichester, 1996.
- (1996) Nuclear Magnetic Resonance Concepts and Methods
- Canet, D.¹

49
- 33847534249
- Carr, H. Y.; Purcell, E. M. Phys. Rev. 1954, 94, 630-638.
- (1954) Phys. Rev. , vol.94 , pp. 630-638
- Carr, H.Y.¹ Purcell, E.M.²

50
- 0002899752
- Meiboom S.; Gill, D. Rev. Sci. Instrum. 1958, 29, 688.
- (1958) Rev. Sci. Instrum. , vol.29 , pp. 688
- Meiboom, S.¹ Gill, D.²

51
- 0003966984
- Academic Press: New York
- Farrar T. C.; Becker, E. D. Pulse and Fourier Transform NMR, Introduction to Theory and Methods; Academic Press: New York, 1971.
- (1971) Pulse and Fourier Transform NMR, Introduction to Theory and Methods
- Farrar, T.C.¹ Becker, E.D.²

52
- 36849127400
- (a) Luz, Z.; Meiboom, S. J. Chem. Phys. 1963, 39, 366-370.
- (1963) J. Chem. Phys. , vol.39 , pp. 366-370
- Luz, Z.¹ Meiboom, S.²

53
- 0012500904
- (b) Allerhand, A.; Gutowsky, H. S. J. Chem. Phys. 1964, 41, 2115-2126.
- (1964) J. Chem. Phys. , vol.41 , pp. 2115-2126
- Allerhand, A.¹ Gutowsky, H.S.²

54
- 0000044516
- Raber, H.; Mehring M. Chem. Phys. 1977, 26, 123-130.
- (1977) Chem. Phys. , vol.26 , pp. 123-130
- Raber, H.¹ Mehring, M.²

55
- 0003626648
- Academic Press: San Diego
- Theodore, P., Jr. All about Albumin Biochemistry, Genetics, and Medical Applications; Academic Press: San Diego, 1996.
- (1996) All About Albumin Biochemistry, Genetics, and Medical Applications
- Theodore P., Jr.¹

56
- 36849135646
- Swift, T. J.; Connick, R. E. J. Chem. Phys. 1962, 37, 307-320.
- (1962) J. Chem. Phys. , vol.37 , pp. 307-320
- Swift, T.J.¹ Connick, R.E.²

57
- 48749144559
- Shaka, A. J.; Keeler, J.; Freeman, R. J. Magn. Reson. 1983, 53, 313-340.
- (1983) J. Magn. Reson. , vol.53 , pp. 313-340
- Shaka, A.J.¹ Keeler, J.² Freeman, R.³

58
- 0024356301
- Wiseman, T.; Williston, S.; Brandts, J. F.; Lin L. Anal. Biochem. 1989. 179, 131-137.
- (1989) Anal. Biochem. , vol.179 , pp. 131-137
- Wiseman, T.¹ Williston, S.² Brandts, J.F.³ Lin, L.⁴

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