NMR-based screening with competition water-ligand observed via gradient spectroscopy experiments: Detection of high-affinity ligands

Journal of Medicinal Chemistry

Volumn 45, Issue 12, 2002, Pages 2610-2614

  Dalvit, Claudio ^a   Fasolini, Marina ^a   Flocco, Maria ^a   Knapp, Stefan ^a   Pevarello, Paolo ^a   Veronesi, Marina ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; LIGAND; PLANT EXTRACT; RNA; WATER;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; CALCULATION; DISSOCIATION CONSTANT; DRUG DNA BINDING; DRUG SCREENING; FUNGUS; LIGAND BINDING; MATHEMATICAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RNA BINDING;

ALGORITHMS; BINDING, COMPETITIVE; DRUG EVALUATION, PRECLINICAL; FUNGI; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; PLANT EXTRACTS; PROTEIN BINDING; PROTEINS; SERUM ALBUMIN; TRYPTOPHAN; WATER;

EID: 0037030693     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm011122k     Document Type: Article

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