Effect of interleukin-1β on the release of substance P from rat isolated spinal cord

European Journal of Pharmacology

Volumn 299, Issue 1-3, 1996, Pages 113-118

  Malcangio, Marzia ^a,c   Bowery, Norman G ^a,d   Flower, Roderick J ^b   Perretti, Mauro ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

CGRP (calcitonin gene related peptide); Hyperalgesia; Indomethacin; interleukin 1 receptor antagonist

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; CYTOKINE; INDOMETACIN; NEUROPEPTIDE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT INTERLEUKIN 1BETA; SUBSTANCE P;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; ELECTROSTIMULATION; HYPERALGESIA; IMMUNOREACTIVITY; INFLAMMATION; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALCITONIN GENE-RELATED PEPTIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; INDOMETHACIN; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MALE; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SIALOGLYCOPROTEINS; SPINAL CORD; SUBSTANCE P;

EID: 0029670561     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00845-4     Document Type: Article

References (27)

1. Andreeva, L. and H.P, Rang, 1993, Effect of bradykinin and prostaglandins on the release of calcitonin gene-related peptide-like immunoreactivity from the rat spinal cord in vitro, Br. J. Pharmacol. 108, 185.
2. Banks, W.A., L. Ortiz, S.R. Plotkin and A.J. Kastin, 1991, Human interleukin (IL) 1α, murine IL-1α and murine IL-1β are transported from blood to brain in the mouse by a shared saturable mechanism, J. Pharmacol. Exp. Ther. 259, 988.
3. Banks, W.A., A.J. Kastin and C.A. Ehrensing, 1994, Blood-borne interleukin-1α is transported across the endothelial blood-spinal cord barrier of mice, J. Physiol. (London) 479, 257.
4. 2 receptor mechanisms in cytokine-induced mechanical hyperalgesia in the rat, Br. J. Pharmacol. 113, 63.
5. Dinarello, C.A., 1991, Interleukin-1 and interleukin-1 antagonism, Blood 77, 1627.
6. Eisenberg, S.P., R.J. Evans, W.P. Arend, E. Verderber, M.T. Brewer, C.H. Hannum and R.C. Thompson, 1990, Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist, Nature 343, 341.
7. Eskay, R.L. and L.E. Eiden, 1992, Interleukin-1α and tumor necrosis factor-α differentially regulate enkephalin, vasoactive intestinal polypeptide, neurotensin, and substance P biosynthesis in chromaffin cells, Endocrinology 130, 2252.
8. Ferreira, S.H., B.B. Lorenzetti, A.F. Bristow and S. Poole, 1988, Interleukin-1β as a potent hyperalgesic agent antagonized by tripeptide analogue, Nature 334, 698.
9. Follenfant, R.L., M. Nakamura-Craig, B. Henderson and G.A. Higgs, 1991, Inhibition by neuropeptides of interleukin-1β-induced, prostaglandin-independent hyperalgesia, Br. J. Pharmacol. 98, 41.
10. Hurst, S.M., A.M. Stanisz, K.A. Sharkey and S.M. Collins, 1993, Interleukin-Iβ-induced increase in substance P in rat myenteric plexus, Gastroenterology 105, 1754.
11. Konttinen, Y.T., P. Kemppinen, M. Segerberg, M. Hukkanen, R. Rees, S. Santavirta, T. Sorsa, A. Pertovaara and J.M. Polak, 1994, Peripheral and spinal neural mechanisms in arthritis, with particular reference to treatment of inflammation and pain, Arthritis Rheum. 37, 965.
12. Levine, J.D., H.L. Fields and A.I. Basbaum, 1993, Peptides and primary afferent nociceptor, Neuroscience 13, 2273.
13. A, receptor activation, inhibits electrically-evoked substance P-like immunoreactivity from rat spinal cord in vitro, J. Pharmacol. Exp. Ther. 266, 1490.
14. 1 receptor antagonists, RP 67580 and SR 140333, on electrically-evoked substance P release from rat spinal cord, Br. J. Pharmacol, 113, 635.
15. Malcangio, M. and N.G. Bowery, 1995, Calcitonin gene-related peptide content, basal outflow and electrically-evoked release from monoarthritic rat spinal cord in vitro, Pain (in press).
16. Malmberg. A.B. and T.L. Yaksh, 1992, Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition, Science 257, 1276.
17. McIntyre, K.W., G.J. Stepan, K.D. Kolisnky, W.R. Benjamin, J.M. Plocinski, K.L. Kaffka, C.A. Campen, R.A. Chizzonite and P.L. Kilian, 1991, Inhibition of interleukin 1 (IL-1) binding and bioactivity in vitro and modulation of acute inflammation in vivo by IL-1 receptor antagonist and anti-IL-1 receptor monoclonal antibody, J. Exp. Med. 173, 931.
18. McMahan, C.J., J.L. Slack, B. Mosley, D. Cosman, S.D. Lupton, L.L. Brunton, C.E. Grubin, J.M. Wignall, N.A. Jenskins, C.I. Brannan, N.G. Copeland, K. Huebner, C.M. Croce, L.A. Cannizzaro, D. Benjamin, S.K. Dower, M.K. Spriggs and J.E. Sims, 1991, A novel IL-1 receptor, cloned from B cells by mammalin expression, is expressed in many cell types, EMBO J. 10, 2821.
19. Meller, S.T., C. Dykstra, D. Grzybycki, S. Murphy and G.F. Gebhart, 1994, The possible role of glia in nociceptive processing and hyperalgesia in the spinal cord of the rat, Neuropharmacology 33, 1471.
20. Mugridge, K.G., D. Donati, S. Silvestri and L. Parente, 1989, Arachidonic acid lipoxygenation may be involved in interleukin-1 induction of prostaglandin biosynthesis, J. Pharmacol. Exp. Ther. 250, 714.
21. Nakamura, H., K. Nakanishi, A. Kita and T. Kadokawa, 1988, Interleukin-1 induces analgesia in mice by a central action, Eur. J. Pharmacol. 149, 49.
22. O'Byrne, E.M., V. Blancuzzi, D.E. Wilson, M. Wong and A.Y. Jeng, 1990, Elevated substance P and accelerated cartilage degradation in rabbit knees injected with interleukin-1 and tumor necrosis factor, Arthritis Rheum. 33, 1023.
23. Oka, T., S. Aou and T. Hori, 1994, Intracerebroventricular injection of interleukin-1β enhances nociceptive neuronal responses of the trigeminal nucleus caudalis in rats, Brain Res. 656, 236.
24. Perretti, M., A. Ahluwalia, R.J. Flower and S. Manzini, 1993, Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors, Immunology 80, 73.
25. 2α, Brain Res. 373, 81.
26. Watkins, L.R., E.P. Wiertelak, L.E. Goehler, K.P. Smith, D. Martin and S.F. Maier, 1994, Characterization of cytokine-induced hyperalgesia, Brain Res. 654, 15.
27. Watkins, L.R., S.F. Maier and L.E. Goehler, 1995, Cytokine-to-brain communication: a review and analysis of alternative mechanisms, Life Sci. 57, 1011.