The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia

Neuroscience

Volumn 78, Issue 3, 1997, Pages 843-850

  Hay, C H ^a   Trevethick, M A ^b,c   Wheeldon, A ^b,d   Bowers, J S ^b   De Belleroche, J S ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d Sandoz Institute for Medical Research   (United Kingdom)

Author keywords

allodynia; cyclooxygenase 2; hyperalgesia; messenger RNA; prostaglandins; spinal cord

Indexed keywords

5 (4 FLUOROPHENYL) 1 [(4 METHYLSULFONYL)PHENYL] 3 TRIFLUOROMETHYLPYRAZOLE; 5 BROMO 2 (4 FLUOROPHENYL) 3 (4 METHYLSULFONYLPHENYL)THIOPHENE; 6 OXOPROSTAGLANDIN F1 ALPHA; CYCLOOXYGENASE 2; FLOSULIDE; FREUND ADJUVANT; INDOMETACIN; MESSENGER RNA; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOOT; HYPERALGESIA; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0030938416     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(96)00598-2     Document Type: Article

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