Ultrastructural localization of increased neuropeptide immunoreactivity in the axons and cells of the gracile nucleus following chronic constriction injury of the sciatic nerve

Neuroscience

Volumn 93, Issue 1, 1999, Pages 335-348

  Ma, W ^a   Bisby, M A ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Calcitonin gene related peptide; Electron microscopy; Galanin; Immunocytochemistry; In situ hybridization; Neuropeptide Y

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; GALANIN; NEUROPEPTIDE Y;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTRON MICROSCOPY; GRACILE NUCLEUS; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; LIGATION; MALE; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SCIATIC NERVE;

ANIMALS; AXONS; CALCITONIN GENE-RELATED PEPTIDE; CHRONIC DISEASE; CONSTRICTION, PATHOLOGIC; GALANIN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MEDULLA OBLONGATA; MICROSCOPY, IMMUNOELECTRON; NEURONS; NEUROPEPTIDE Y; NEUROPEPTIDES; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SCIATIC NERVE;

EID: 0033002714     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00145-1     Document Type: Article

References (63)

1. Amara S.G., Arriza J.L., Leff S.E., Swanson L.W., Evans R.M., Rosenfeld M.G. Expression in brain of a messenger RNA encoding a novel neuropeptide homologous to calcitonin gene-related peptide. Science. 229:1985;1094-1097.
2. Anderson P., Eccles J.C., Voorhoeve P.E. Inhibitory synapses on somas of Purkinje cells in the cerebellum. Nature, Lond. 199:1963;655-656.
3. Bauerfeind R., Huttner W.B. Biogenesis of constitutive secretory vesicles, secretory granules and synaptic vesicles. Curr. Opin. Cell Biol. 5:1993;628-635.
4. Bennett G.J., Xie Y.K. A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain. 33:1988;87-107.
5. Carlton S.M., Coggeshall R.E. Stereological analysis of galanin and CGRP synapses in the dorsal horn of neuropathic primates. Brain Res. 711:1996;16-25.
6. Ch'ng J.L., Christofides N.D., Anand P., Gibson S.J., Allen Y.S., Su H.C., Tatemoto K., Morrison J.F., Polak J.M., Bloom S.R. Distribution of galanin immunoreactivity in the central nervous system and the responses of galanin-containing neuronal pathways to injury. Neuroscience. 16:1985;343-354.
7. Chronwall B.M., DiMaggio D.A., Massari V.J., Pickel V.M., Ruggiero D.A., O'Donohue T.L. The anatomy of neuropeptide Y-containing neurons in rat brain. Neuroscience. 15:1985;1159-1181.
8. De Camilli P., Jahn R. Pathways to regulated exocytosis in neurons. A. Rev. Physiol. 52:1990;625-645.
9. de Quidt M.E., Emson P.C. Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system - II. Immunohistochemical analysis. Neuroscience. 18:1986;545-618.
10. de Quidt M.E., Emson P.C. Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system - I. Radioimmunoassay and chromatographic characterisation. Neuroscience. 18:1986;527-543.
11. Eccles J. C. (1964) In The Physiology of Synapses. Anonymous. Springer, Berlin.
12. Fujiwara K., Baek S.Y., Arakawa T., Kobayashi K., Takagi H. Calcitonin gene-related peptide- and substance P-immunoreactive axons in the axons in the nucleus gracilis of the rat with special reference to axonal dystrophy - light and electron microscopic observations. Acta neuropath. 90:1995;347-355.
13. Gibson S.J., Polak J.M., Bloom S.R., Sabate I.M., Mulderry P.M., Ghatei M.A., McGregor G.P., Morrison J.F., Kelly J.S., Evans R.M., Rosenfeld M.G. Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species. J. Neurosci. 4:1984;3101-3111.
14. Gundlach A.L., Wisden W., Morris B.J., Hunt S.P. Localization of preprogalanin mRNA in rat brain: in situ hybridization study with a synthetic oligonucleotide probe. Neurosci. Lett. 114:1990;241-247.
15. Gustafson E.L., Smith K.E., Durkin M.M., Walker M.W., Gerald C., Weinshank R., Branchek T.A. Distribution of the neuropeptide Y Y2 receptor mRNA in rat central nervous system. Molec. Brain Res. 1:1994;223-235.
16. Hokfelt T., Wiesenfeld-Hallin Z., Villar M., Melander T. Increase of galanin-like immunoreactivity in rat dorsal root ganglion cells after peripheral axotomy. Neurosci. Lett. 83:1987;217-220.
17. Hokfelt T., Zhang X., Wiesenfeld-Hallin Z. Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci. 17:1994;22-30.
18. Hua X.Y., Boublik J.H., Spicer M.A., Rivier J.E., Brown M.R., Yaksh T.L. The antinociceptive effects of spinally administered neuropeptide Y in the rat: systematic studies on structure-activity relationship. J. Pharmac. exp. Ther. 258:1991;243-248.
19. Jessell T., Tsunoo A., Kanazawa I., Otsuka M. Substance P: depletion in the dorsal horn of rat spinal cord after section of the peripheral process of primary sensory neurons. Brain Res. 168:1979;247-259.
20. Kashiba H., Noguchi K., Ueda Y., Senba E. Neuropeptide Y and galanin are coexpressed in rat large type A sensory neurons after peripheral transection. Peptides. 15:1994;411-416.
21. Kashiba H., Ueda Y., Senba E. Systemic capsaicin in the adult rat differentially affects gene expression for neuropeptides and neurotrophin receptors in primary sensory neurons. Neuroscience. 76:1997;299-312.
22. Knyihar-Csillik E., Kreutzberg G.W., Csillik B. Fine structural correlates of VIP-like immunoreactivity in the upper spinal dorsal horn after peripheral axotomy: possibilities of a neuro-glial translocation of a neuropeptide. Acta histochem. 94:1993;1-12.
23. 125I][leu31,pro34]-NPY binding sites and neurons expressing Y1 receptor mRNA. J. Receptor Signal Transduction Res. 15:1995;457-472.
24. Lee Y., Takami K., Kaway Y., Girgis S., Hillyard C.J., Maclntyre I., Emson P.C., Tohyama M. Distribution of calcitonin gene-related peptide in the rat peripheral nervous system with reference to its coexistence with substance P. Neuroscience. 16:1985;1227-1237.
25. Llewellyn-Smith I.J., Minson J.B. Complete penetration of antibodies into vibratome sections after glutaraldehyde fixation and ethanol treatment: light and electron microscopy for neuropeptides. J. Histochem. Cytochem. 40:1992;1741-1749.
26. Ma W., Bisby M.A. Differential expression of galanin immunoreactivities in the primary sensory neurons following partial and complete sciatic nerve injuries. Neuroscience. 79:1997;1183-1195.
27. Ma W., Bisby M.A. Partial and compete sciatic nerve injuries induced similar increases of neuropeptide Y and vasoactive intestinal peptide immunoreactivities in primary sensory neurons and their central projections in the dorsal horn and the gracile nuclei. Neuroscience. 84:1998;1217-1224.
28. Ma W., Bisby M.A. Increase of calcitonin gene-related peptide immunoreactivity in the axonal fibers of the gracile nculei of adult and aged rats after complete and partial sciatic nerve injuries. Expl Neurol. 152:1998;137-149.
29. Ma W.Y., Ribeiro da Silva A., Noel G., Julien J.P., Cuello A.C. Ectopic substance P and calcitonin gene-related peptide immunoreactive fibers in the spinal cord of transgenic mice overexpressing nerve growth factor. Eur. J. Neurosci. 7:1995;2021-2035.
30. Martel J.C., St-Pierre S., Quirion R. Neuropeptide Y receptors in rat brain: autoradiographic localization. Peptides. 7:1986;55-60.
31. Melander T., Hokfelt T., Nilsson S., Brodin E. Visualization of galanin binding sites in the rat central nervous system. Eur. J. Pharmac. 124:1986;381-382.
32. Melander T., Hokfelt T., Rokaeus A. Distribution of galanin like immunoreactivity in the rat central nervous system. J. comp. Neurol. 248:1986;475-517.
33. Miki K., Fukuoka T., Tokunaga A., Noguchi K. Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peirpheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons. Neuroscience. 82:1997;1243-1252.
34. Noguchi K., Kawai Y., Fukuoka T., Senba E., Miki K. Substance P induced by peripheral nerve injury in primary afferent sensory neurons and its effect on dorsal column nucleus neurons. J. Neurosci. 15:1995;7633-7643.
35. Noguchi K., Senba E., Morita Y., Sato M., Tohyama M. α-CGRP and β-CGRP mRNAs are differentially regulated in the rat spinal cord and dorsal root ganglion. Molec. Brain Res. 7:1990;299-304.
36. Ohara S., Beaudet L.N., Schmidt R.E. Transganglionic response of GAP-43 in the gracile nucleus to sciatic nerve injury in young and aged rats. Brain Res. 705:1995;325-331.
37. Ohara S., Roth K.A., Beaudet L.N., Schmidt R.E. Transganglionic neuropeptide Y response to sciatic nerve injury in young and aged rats. J. Neuropath. exp. Neurol. 53:1994;646-662.
38. Persson J.K., Aldskogius H., Arvidsson J., Holmberg A. Ultrastructural changes in the gracile nucleus of the rat after sciatic nerve transection. Anat. Embryol. 184:1991;591-604.
39. Peters A., Palay S. L. and Webster H. d. (eds) (1991) The neuronal cell body. In The Fine Structure of the Nervous System, pp. 14-64. Oxford University Press, New York.
40. Peters A., Palay S. L. and Webster H. d. (eds) (1991) The neuroglial cells. In The Fine Structure of the Nervous System, pp. 273-308. Oxford University Press, New York.
41. Rosenfeld M.G., Mermod J.J., Amara S.G., Swanson L.W., Sawchenko P.E., Rivier J., Vale W.W., Evans R.M. Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing. Nature. 304:1983;129-135.
42. Saika T., Senba E., Noguchi K., Sato M., Kubo T., Matsunaga T., Tohyama M. Changes in expression of peptides in rat facial motoneurons after facial nerve crushing and resection. Molec. Brain Res. 3-4:1991;187-196.
43. Shu S., Ju G., Fan L. The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system. Neurosci. Lett. 85:1988;169-171.
44. Skofitsch G., Jacobowitz D.M. Immunohistochemical mapping of galanin-like neurons in the rat central nervous system. Peptides. 6:1985;509-546.
45. Skofitsch G., Jacobowitz D.M. Quantitative distribution of galanin-like immunoreactivity in the rat central nervous system. Peptides. 7:1986;609-613.
46. 125I-galanin binding sites in the rat central nervous system. Peptides. 7:1986;1029-1042.
47. Tessler A., Himes B.T., Krieger N.R., Murray M., Goldberger M.E. Sciatic nerve transection produces death of dorsal root ganglion cells and reversible loss of substance P in spinal cord. Brain Res. 332:1985;209-218.
48. Villar M.J., Cortes R., Theodorsson E., Wiesenfeld-Hallin Z., Schalling M., Fahrenkrug J., Emson P.C., Hokfelt T. Neuropeptide expression in rat dorsal root ganglion cells and spinal cord after peripheral nerve injury with special reference to galanin. Neuroscience. 33:1989;587-604.
49. Vrontakis M.E., Peden L.M., Duckworth M.L., Friesen H.G. Isolation and characterization of a complementary DNA (galanin) clone from estrogen-induced pituitary tumor messenger RNA. J. biol. Chem. 262:1987;16,755-16,758.
50. Wakisaka S., Kajander K.C., Bennett G.J. Increased neuropeptide-Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy. Neurosci. Lett. 124:1991;200-203.
51. Wakisaka S., Kajander K.C., Bennett G.J. Effects of peripheral nerve injuries and tissue inflammation on the levels of neuropeptide-Y-like immunoreactivity in rat primary afferent neurons. Brain Res. 598:1992;349-352.
52. White D.M., Mansfield K. Vasoactive intestinal polypeptide and neuropeptide and neuropeptide Y act indirectly to increase neurite outgrowth of dissociated dorsal root ganglion cells. Neuroscience. 73:1996;881-887.
53. Wiesenfeld-Hallin Z., Hokfelt T., Lundberg J.M., Forssmann W.G., Reinecke M., Tschopp F.A., Fischer J.A. Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral responses of the rat. Neurosci. Lett. 52:1984;199-204.
54. Wiesenfeld-Hallin Z., Villar M.J., Hokfelt T. Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli. Expl Brain Res. 71:1988;663-666.
55. Wiesenfeld-Hallin Z., Villar M.J., Hokfelt T. The effect of intrathecal galanin and C-fiber stimulation on the flexor reflex in the rat. Brain Res. 486:1989;205-213.
56. Wiesenfeld-Hallin Z., Xu X.-J., Langel U., Bedecs K., Hokfelt T., Bartfai T. Galanin-mediated control of pain: enhanced role after nerve injury. Proc. natn. Acad. Sci. U.S.A. 89:1992;3334-3337.
57. Wiesenfeld-Hallin Z., Xu X.-J., Villar M., Hokfelt T. The effect of galanin on the flexor reflex in rat: increased depression after sciatic nerve section. Neurosci. Lett. 105:1989;149-154.
58. Woolf C.J., Wiesenfeld-Hallin Z. Substance P and calcitonin gene-related peptide synergistically modulate the gain of the nociceptive flexor withdrawal reflex in the rat. Neurosci. Lett. 66:1986;226-230.
59. Zhang X., Aman K., Hokfelt T. Secretory pathways of neuropeptides in rat lumbar dorsal root ganglion neurons and effects of peripheral axotomy. J. comp. Neurol. 352:1995;481-500.
60. Zhang X., Bean A.J., Wiesenfeld-Hallin Z., Hokfelt T. Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord - IV. Effects of peripheral axotomy with special reference to neuropeptide Y and vasoactive intestinal polypeptide/peptide histidine isoleucine. Neuroscience. 64:1995;917-941.
61. Zhang X., Bean A.J., Wiesenfeld-Hallin Z., Xu X.J., Hokfelt T. Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord - III. Effects of peripheral axotomy with special reference to galanin. Neuroscience. 64:1995;893-915.
62. Zhang X., Meister B., Elde R., Verge V.M.K., Hokfelt T. Large calibre primary afferent neurons projecting to the gracile nucleus express neuropeptide-Y after sciatic nerve lesions - an immunohistochemical and in situ hybridization study in rats. Eur. J. Neurosci. 5:1993;1510-1519.
63. Zhang X., Wiesenfeld-Hallin Z., Hokfelt T. Effect of peripheral axotomy on expression of neuropeptide Y receptor mRNA in rat lumbar dorsal root ganglia. Eur. J. Neurosci. 6:1994;43-57.