Reversal of multidrug resistance by kopsiflorine isolated from Kopsia dasyrachis

Planta Medica

Volumn 65, Issue 4, 1999, Pages 307-310

  Rho, Mun Chual ^a   Toyoshima, Mitsuhide ^a   Hayashi, Masahiko ^a   Koyano, Takashi ^b   Subramaniam, Gurusamy ^c   Kam, Toh Seok ^c   Komiyama, Kanki ^a  

^a KITASATO INSTITUTE   (Japan)

^b Temko Corporation   (Japan)

^c UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

Apocynaceae; Kopsia dasyrachis; Kopsiflorine; Multidrug resistance; P glycoprotein

Indexed keywords

ANTINEOPLASTIC AGENT; AZIDOPINE; CYCLOSPORIN; GLYCOPROTEIN P; INDOLE ALKALOID; KOPSIFLORINE; PLANT EXTRACT; STEROID; UNCLASSIFIED DRUG; VERAPAMIL; VINCRISTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; NONHUMAN;

DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; INDOLES; INDOLIZINES; PLANTS; TUMOR CELLS, CULTURED;

APOCYNACEAE; KOPSIA; KOPSIA DASYRACHIS;

EID: 0033008034     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1999-13991     Document Type: Article

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