Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:Quinone oxidoreductase in rat liver

Cancer Research

Volumn 60, Issue 4, 2000, Pages 957-969

  Kelly, Vincent P ^a   Ellis, Elizabeth M ^a,d   Manson, Margaret M ^b   Chanas, Simon ^a   Moffat, Graeme J ^c   McLeod, Ronald ^a   Judah, David J ^b   Neal, Gordon E ^b   Hayes, John D ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

^d UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3 INDOLEMETHANOL; AFLATOXIN B1; ALDEHYDE REDUCTASE; BENZYL ISOTHIOCYANATE; BETA NAPHTHOFLAVONE; BUTYLATED HYDROXYANISOLE; COUMARIN; ETHOXYQUIN; GLUTATHIONE TRANSFERASE; MALEIC ACID DIETHYL ESTER; OLTIPRAZ; OXIDOREDUCTASE; PHENOBARBITAL; PYRONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRANS STILBENE OXIDE; AFLATOXIN B1 ALDEHYDE REDUCTASE; COUMARIN DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE);

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; GENE OVEREXPRESSION; LIVER CARCINOGENESIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; FISCHER 344 RAT; LIVER; LIVER TUMOR; METABOLISM; PRECANCER; RABBIT; SEX DIFFERENCE;

AFLATOXIN B1; ALDEHYDE REDUCTASE; ANIMALS; COUMARINS; ENZYME INDUCTION; FEMALE; GLUTATHIONE TRANSFERASE; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; PRECANCEROUS CONDITIONS; QUINONE REDUCTASES; RABBITS; RATS; RATS, INBRED F344; SEX FACTORS;

EID: 0034651240     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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