-
1
-
-
0028915798
-
Proline-rich sequences that hind to Src homology 3 domains with individual specificities
-
Alexandropoulos, K., G. Cheng, and D. Baltimore. 1995. Proline-rich sequences that hind to Src homology 3 domains with individual specificities. Proc. Natl. Acad. Sci. USA 92:3110-3114.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3110-3114
-
-
Alexandropoulos, K.1
Cheng, G.2
Baltimore, D.3
-
2
-
-
0030791113
-
Involvement of p53 in cell differentiation and development
-
Almog, N., and V. Rotter. 1997. Involvement of p53 in cell differentiation and development. Biochim. Biophys. Acta 1333:F1-F27.
-
(1997)
Biochim. Biophys. Acta
, vol.1333
-
-
Almog, N.1
Rotter, V.2
-
3
-
-
0028049474
-
Regulation of mdm2 expression by p53: Alternative promoters produce transcripts with nonidentical translation potential
-
Barak, Y., E. Gottlieb, T. Juven-Gershon, and M. Oren. 1994. Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential. Genes Dev. 8:1739-1749.
-
(1994)
Genes Dev.
, vol.8
, pp. 1739-1749
-
-
Barak, Y.1
Gottlieb, E.2
Juven-Gershon, T.3
Oren, M.4
-
4
-
-
0027459198
-
mdm2 expression is induced by wild type p53 activity
-
Barak, Y., T. Juven, R. Haffner, and M. Oren. 1993. mdm2 expression is induced by wild type p53 activity. EMBO J. 12:461-468.
-
(1993)
EMBO J.
, vol.12
, pp. 461-468
-
-
Barak, Y.1
Juven, T.2
Haffner, R.3
Oren, M.4
-
5
-
-
0029781509
-
Functional interaction of beta-catenin with the transcription factor LEF-1
-
Behrens, J., J. P. von Kris, M. Kuhl, L. Bruhn, D. Wedlich, R. Grosschedl, and W. Birchmeier. 1996. Functional interaction of beta-catenin with the transcription factor LEF-1. Nature 382:638-642.
-
(1996)
Nature
, vol.382
, pp. 638-642
-
-
Behrens, J.1
Von Kris, J.P.2
Kuhl, M.3
Bruhn, L.4
Wedlich, D.5
Grosschedl, R.6
Birchmeier, W.7
-
6
-
-
0028568639
-
A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors
-
Blaikie, P., D. Immanuel, J. Wu, N. Li, V. Yajnik, and B. Margolis. 1994. A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors. J. Biol. Chem. 269:32031-32034.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32031-32034
-
-
Blaikie, P.1
Immanuel, D.2
Wu, J.3
Li, N.4
Yajnik, V.5
Margolis, B.6
-
7
-
-
0023339504
-
Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
-
Cahilly-Snyder, L., F. T. Yang, U. Francke, and D. L. George. 1987. Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line. Somat. Cell Mol. Genet. 13:235-244.
-
(1987)
Somat. Cell Mol. Genet.
, vol.13
, pp. 235-244
-
-
Cahilly-Snyder, L.1
Yang, F.T.2
Francke, U.3
George, D.L.4
-
8
-
-
0028221013
-
Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway
-
Chen, C. Y., J. D. Oliner, Q. Zhan, A. J. Fornace, B. Vogelstein, and M. B. Kastan. 1994. Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway. Proc. Natl. Acad. Sci. USA 91:2684-2688.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2684-2688
-
-
Chen, C.Y.1
Oliner, J.D.2
Zhan, Q.3
Fornace, A.J.4
Vogelstein, B.5
Kastan, M.B.6
-
9
-
-
0027222956
-
Mapping of the p53 and mdm-2 interaction domains
-
Chen, J., V. Marechal, and A. J. Levine. 1993. Mapping of the p53 and mdm-2 interaction domains. Mol. Cell. Biol. 13:4107-4114.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4107-4114
-
-
Chen, J.1
Marechal, V.2
Levine, A.J.3
-
10
-
-
0029913730
-
1 arrest and apoptosis functions of the p53 tumor suppressor protein
-
1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol. Cell. Biol. 16:2445-2452.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2445-2452
-
-
Chen, J.1
Wu, X.2
Lin, J.3
Levine, A.J.4
-
11
-
-
0028098165
-
Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas
-
Cordon-Cardo, C., E. Latres, M. Drohnjak, M. R. Oliva, D. Pollack, J. M. Woodruff, V. Marechal, J. Chen, M. F. Brennan, and A. J. Levine. 1994. Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas. Cancer Res. 54:794-799.
-
(1994)
Cancer Res.
, vol.54
, pp. 794-799
-
-
Cordon-Cardo, C.1
Latres, E.2
Drohnjak, M.3
Oliva, M.R.4
Pollack, D.5
Woodruff, J.M.6
Marechal, V.7
Chen, J.8
Brennan, M.F.9
Levine, A.J.10
-
12
-
-
0028946095
-
Non-syntenic amplification of MDM2 and MYCN in human neuroblastoma
-
Corvi, R., L. Savelyeva, S. Breit, A. Wenzel, R. Handgretinger, J. Barak, M. Oren, L. Amler, and M. Schwab. 1995. Non-syntenic amplification of MDM2 and MYCN in human neuroblastoma. Oncogene 10:1081-1086.
-
(1995)
Oncogene
, vol.10
, pp. 1081-1086
-
-
Corvi, R.1
Savelyeva, L.2
Breit, S.3
Wenzel, A.4
Handgretinger, R.5
Barak, J.6
Oren, M.7
Amler, L.8
Schwab, M.9
-
13
-
-
0029590161
-
MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest
-
Dubs-Poterszman, M., B. Tocque, and B. Wasylyk. 1995. MDM2 transformation in the absence of p53 and abrogation of the p107 G1 cell-cycle arrest. Oncogene 11:2445-2449.
-
(1995)
Oncogene
, vol.11
, pp. 2445-2449
-
-
Dubs-Poterszman, M.1
Tocque, B.2
Wasylyk, B.3
-
14
-
-
0027251721
-
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit
-
Durfee, T., K. Becherer, P. L. Chen, S. H. Yeh, Y. Yang, A. E. Kilburn, W. H. Lee, and S. J. Elledge. 1993. The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev. 7:555-569.
-
(1993)
Genes Dev.
, vol.7
, pp. 555-569
-
-
Durfee, T.1
Becherer, K.2
Chen, P.L.3
Yeh, S.H.4
Yang, Y.5
Kilburn, A.E.6
Lee, W.H.7
Elledge, S.J.8
-
15
-
-
0029760621
-
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain
-
Elenbaas, B., M. Dobbelstein, J. Roth, T. Shenk, and A. J. Levine. 1996. The MDM2 oncoprotein binds specifically to RNA through its RING finger domain. Mol. Med. 2:439-451.
-
(1996)
Mol. Med.
, vol.2
, pp. 439-451
-
-
Elenbaas, B.1
Dobbelstein, M.2
Roth, J.3
Shenk, T.4
Levine, A.J.5
-
16
-
-
0025853776
-
Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
-
Fakharzadeh, S. S., S. P. Trusko, and D. L. George. 1991. Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J. 10:1565-1569.
-
(1991)
EMBO J.
, vol.10
, pp. 1565-1569
-
-
Fakharzadeh, S.S.1
Trusko, S.P.2
George, D.L.3
-
17
-
-
0029743891
-
Amplification of MDM2 inhibits MyoD-mediated myogenesis
-
Fiddler, T. A., L. Smith, S. J. Tapscott, and M. J. Thayer. 1996. Amplification of MDM2 inhibits MyoD-mediated myogenesis. Mol. Cell. Biol. 16: 5048-5057.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 5048-5057
-
-
Fiddler, T.A.1
Smith, L.2
Tapscott, S.J.3
Thayer, M.J.4
-
18
-
-
0027498314
-
The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
-
Finlay, C. A. 1993. The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth. Mol. Cell. Biol. 13:301-306.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 301-306
-
-
Finlay, C.A.1
-
19
-
-
0030981049
-
A genetic approach to mapping the p53 binding site in the MDM2 protein
-
Freedman, D. A., C. B. Epstein, J. C. Roth, and A. J. Levine. 1997. A genetic approach to mapping the p53 binding site in the MDM2 protein. Mol. Med. 3:248-259.
-
(1997)
Mol. Med.
, vol.3
, pp. 248-259
-
-
Freedman, D.A.1
Epstein, C.B.2
Roth, J.C.3
Levine, A.J.4
-
20
-
-
0029909203
-
The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage
-
Frise, E., J. A. Knoblich, S. S. Younger, L. Y. Jan, and Y. N. Jan. 1996. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc. Natl. Acad. Sci. USA 93:11925-11932.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11925-11932
-
-
Frise, E.1
Knoblich, J.A.2
Younger, S.S.3
Jan, L.Y.4
Jan, Y.N.5
-
21
-
-
0030199973
-
Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch
-
Guo, M., L. Y. Jan, and Y. N. Jan. 1996. Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17:27-41.
-
(1996)
Neuron
, vol.17
, pp. 27-41
-
-
Guo, M.1
Jan, L.Y.2
Jan, Y.N.3
-
22
-
-
0028147405
-
Physical and functional interaction between wild-type p53 and mdm2 proteins
-
Haines, D. S., J. E. Landers, L. J. Engle, and D. L. George. 1994. Physical and functional interaction between wild-type p53 and mdm2 proteins. Mol. Cell. Biol. 14:1171-1178.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1171-1178
-
-
Haines, D.S.1
Landers, J.E.2
Engle, L.J.3
George, D.L.4
-
24
-
-
0027496935
-
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper, J. W., G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75:805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
25
-
-
0029985647
-
Cell type-specific inhibition of p53-mediated apoptosis by mdm2
-
Haupt, Y., Y. Barak, and M. Oren. 1996. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J. 15:1596-1606.
-
(1996)
EMBO J.
, vol.15
, pp. 1596-1606
-
-
Haupt, Y.1
Barak, Y.2
Oren, M.3
-
26
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt, Y., R. Maya, A. Kazaz, and M. Oren. 1997. Mdm2 promotes the rapid degradation of p53. Nature 387:296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
27
-
-
0025193521
-
The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells
-
Heffetz, D., I. Bushkin, R. Dror, and Y. Zick. 1990. The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells. J. Biol. Chem. 265:2896-2902.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 2896-2902
-
-
Heffetz, D.1
Bushkin, I.2
Dror, R.3
Zick, Y.4
-
28
-
-
0031583962
-
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
-
27a. Honda, R., H. Tanaka, and H. Yasuda. 1997. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett. 420:25-27.
-
(1997)
FEBS Lett.
, vol.420
, pp. 25-27
-
-
Honda, R.1
Tanaka, H.2
Yasuda, H.3
-
29
-
-
0030802364
-
A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
-
Israeli, D., E. Tessler, Y. Haupt, A. Elkeles, S. Wilder, R. Amson, A. Telerman, and M. Oren. 1997. A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J. 16:4384-4392.
-
(1997)
EMBO J.
, vol.16
, pp. 4384-4392
-
-
Israeli, D.1
Tessler, E.2
Haupt, Y.3
Elkeles, A.4
Wilder, S.5
Amson, R.6
Telerman, A.7
Oren, M.8
-
30
-
-
0028834902
-
Rescue of embryonic lethality in Mdm2-delicient mice by absence of p53
-
Jones, S. N., A. E. Roe, L. A. Donehower, and A. Bradley. 1995. Rescue of embryonic lethality in Mdm2-delicient mice by absence of p53. Nature 378: 206-208.
-
(1995)
Nature
, vol.378
, pp. 206-208
-
-
Jones, S.N.1
Roe, A.E.2
Donehower, L.A.3
Bradley, A.4
-
31
-
-
0027501841
-
Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene
-
Juven, T., Y. Barak, A. Zauberman, D. L. George, and M. Oren. 1993. Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene. Oncogene 8:3411-3416.
-
(1993)
Oncogene
, vol.8
, pp. 3411-3416
-
-
Juven, T.1
Barak, Y.2
Zauberman, A.3
George, D.L.4
Oren, M.5
-
32
-
-
0028596158
-
An alternative to SH2 domains for binding tyrosine-phosphorylated proteins
-
Kavanaugh, W. M., and L. T. Williams. 1994. An alternative to SH2 domains for binding tyrosine-phosphorylated proteins. Science 266:1862-1865.
-
(1994)
Science
, vol.266
, pp. 1862-1865
-
-
Kavanaugh, W.M.1
Williams, L.T.2
-
33
-
-
0028818805
-
Asymmetric segregation of Numb and Prospero during cell division
-
Knoblich, J. A., L. Y. Jan, and Y. N. Jan. 1995. Asymmetric segregation of Numb and Prospero during cell division. Nature 377:624-627.
-
(1995)
Nature
, vol.377
, pp. 624-627
-
-
Knoblich, J.A.1
Jan, L.Y.2
Jan, Y.N.3
-
34
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M. H., S. N. Jones, and K. H. Vousden. 1997. Regulation of p53 stability by Mdm2. Nature 387:299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
35
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie, P. H., S. Gorina, V. Marechal, B. Elenbaas, J. Moreau, A. J. Levine, and N. P. Pavletich. 1996. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 274:948-953.
-
(1996)
Science
, vol.274
, pp. 948-953
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
Elenbaas, B.4
Moreau, J.5
Levine, A.J.6
Pavletich, N.P.7
-
36
-
-
0027232042
-
p53 Mutation and MDM2 amplification in human soft tissue sarcomas
-
Leach, F. S., T. Tokino, P. Meltzer, M. Burrell, J. D. Oliner, S. Smith, D. E. Hill, D. Sidransky, K. W. Kinzler, and B. Vogelstein. 1993. p53 Mutation and MDM2 amplification in human soft tissue sarcomas. Cancer Res. 53:2231-2234.
-
(1993)
Cancer Res.
, vol.53
, pp. 2231-2234
-
-
Leach, F.S.1
Tokino, T.2
Meltzer, P.3
Burrell, M.4
Oliner, J.D.5
Smith, S.6
Hill, D.E.7
Sidransky, D.8
Kinzler, K.W.9
Vogelstein, B.10
-
37
-
-
0030871250
-
High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif
-
Li S. C., Z. Songyang, S. J. Vincent, C. Zwahlen, S. Wiley, L. Cantley, L. E. Kay, K. J. Forman, and T. Pawson. 1997. High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif. Proc. Natl. Acad. Sci. USA 94:7204-7209.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7204-7209
-
-
Li, S.C.1
Songyang, Z.2
Vincent, S.J.3
Zwahlen, C.4
Wiley, S.5
Cantley, L.6
Kay, L.E.7
Forman, K.J.8
Pawson, T.9
-
38
-
-
14444281159
-
Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53
-
Lundgren, K., R. Montes de Oca Luna, Y. B. McNeill, E. P. Emerick, B. Spencer, C. R. Barfield, G. Lozano, M. P. Rosenberg, and C. A Finlay. 1997. Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. Genes Dev. 11:714-725.
-
(1997)
Genes Dev.
, vol.11
, pp. 714-725
-
-
Lundgren, K.1
Montes De Oca Luna, R.2
McNeill, Y.B.3
Emerick, E.P.4
Spencer, B.5
Barfield, C.R.6
Lozano, G.7
Rosenberg, M.P.8
Finlay, C.A.9
-
39
-
-
0027999512
-
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes
-
Marechal, V., B. Elenbaas, J. Piette, J. C. Nicolas, and A. J. Levine. 1994. The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes. Mol. Cell. Biol. 14:7414-7420.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 7414-7420
-
-
Marechal, V.1
Elenbaas, B.2
Piette, J.3
Nicolas, J.C.4
Levine, A.J.5
-
40
-
-
0029028353
-
Stimulation of E2F/DP1 transcnptional activity by MDM2 oncoprotein
-
Martin, K., D. Trouche, C. Hagemeier, T. S. Sorensen, N. B. La Thangue, and T. Kouzarides. 1995. Stimulation of E2F/DP1 transcnptional activity by MDM2 oncoprotein. Nature 375:691-694.
-
(1995)
Nature
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorensen, T.S.4
La Thangue, N.B.5
Kouzarides, T.6
-
41
-
-
0001003110
-
XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos
-
Molenaar, M., M. van de Wetering, M. Oosterwegel, M. J. Peterson, S. Godsave, V. Korinek, J. Roose, O. Destree, and H. Clevers. 1996. XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos. Cell 86:391-399.
-
(1996)
Cell
, vol.86
, pp. 391-399
-
-
Molenaar, M.1
Van De Wetering, M.2
Oosterwegel, M.3
Peterson, M.J.4
Godsave, S.5
Korinek, V.6
Roose, J.7
Destree, O.8
Clevers, H.9
-
43
-
-
0026649648
-
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
-
Momand, J., G. P. Zambetti, D. C. Olson, D. George, and A. J. Levine. 1992. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69:1237-1245.
-
(1992)
Cell
, vol.69
, pp. 1237-1245
-
-
Momand, J.1
Zambetti, G.P.2
Olson, D.C.3
George, D.4
Levine, A.J.5
-
44
-
-
0028823020
-
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
-
Montes de Oca Luna, R., D. S. Wagner, and G. Lozano. 1995. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 378:203-206.
-
(1995)
Nature
, vol.378
, pp. 203-206
-
-
Montes De Oca Luna, R.1
Wagner, D.S.2
Lozano, G.3
-
45
-
-
0026740449
-
Amplification of a gene encoding a p53-associated protein in human sarcomas
-
Oliner, J. D., K. W. Kinzler, P. S. Meltzer, D. L. George, and B. Vogelstein. 1992. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 358:80-83.
-
(1992)
Nature
, vol.358
, pp. 80-83
-
-
Oliner, J.D.1
Kinzler, K.W.2
Meltzer, P.S.3
George, D.L.4
Vogelstein, B.5
-
46
-
-
0027325132
-
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
-
Oliner, J. D., J. A. Pietenpol, S. Thiagalingam, J. Gyuris, K. W. Kinzler, and B. Vogelstein. 1993. Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53. Nature 362:857-860.
-
(1993)
Nature
, vol.362
, pp. 857-860
-
-
Oliner, J.D.1
Pietenpol, J.A.2
Thiagalingam, S.3
Gyuris, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
47
-
-
0027179604
-
Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes
-
Olson, D. C., V. Marechal, J. Momand, J. Chen, C. Romocki, and A. J. Levine. 1993. Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes. Oncogene 8:2353-2360.
-
(1993)
Oncogene
, vol.8
, pp. 2353-2360
-
-
Olson, D.C.1
Marechal, V.2
Momand, J.3
Chen, J.4
Romocki, C.5
Levine, A.J.6
-
48
-
-
0027291285
-
Upregulation of mdm-2 expression in Meth a tumor cells tolerating wild-type p53
-
Otto, A., and W. Deppert. 1993. Upregulation of mdm-2 expression in Meth A tumor cells tolerating wild-type p53. Oncogene 8:2591-2603.
-
(1993)
Oncogene
, vol.8
, pp. 2591-2603
-
-
Otto, A.1
Deppert, W.2
-
49
-
-
0027143217
-
The mdm-2 gene is induced in response to UV light in a p53-dependent manner
-
Perry, M. E., J. Piette, J. A. Zawadzki, D. Harvey, and A. J. Levine. 1993. The mdm-2 gene is induced in response to UV light in a p53-dependent manner. Proc Natl. Acad. Sci. USA 90:11623-11627.
-
(1993)
Proc Natl. Acad. Sci. USA
, vol.90
, pp. 11623-11627
-
-
Perry, M.E.1
Piette, J.2
Zawadzki, J.A.3
Harvey, D.4
Levine, A.J.5
-
50
-
-
0027673764
-
The p53-mdm2 autoregulatory feedback loop: A paradigm for the regulation of growth control by p53?
-
Picksley, S. M., and D. P. Lane. 1993. The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53? Bioessays 15:689-690.
-
(1993)
Bioessays
, vol.15
, pp. 689-690
-
-
Picksley, S.M.1
Lane, D.P.2
-
51
-
-
0027964904
-
Immunochemical analysis of the interaction of p53 with MDM2;-fine mapping of the MDM2 binding site on p53 using synthetic peptides
-
Picksley, S. M., B. Vojtesek, A. Sparks, and D. P. Lane. 1994. Immunochemical analysis of the interaction of p53 with MDM2;-fine mapping of the MDM2 binding site on p53 using synthetic peptides. Oncogene 9:2523-2529.
-
(1994)
Oncogene
, vol.9
, pp. 2523-2529
-
-
Picksley, S.M.1
Vojtesek, B.2
Sparks, A.3
Lane, D.P.4
-
52
-
-
0030800922
-
Mdm2: Keeping p53 under control
-
Piette, J., H. Neel, and V. Marechal. 1997. Mdm2: keeping p53 under control. Oncogene 15:1001-1010.
-
(1997)
Oncogene
, vol.15
, pp. 1001-1010
-
-
Piette, J.1
Neel, H.2
Marechal, V.3
-
53
-
-
0032549704
-
Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92:713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.-W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
54
-
-
0027196974
-
Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations
-
Reifenberger, G., L. Liu, K. Ichimura, E. E. Schmidt, and V. P. Collins. 1993. Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res. 53:2736-2739.
-
(1993)
Cancer Res.
, vol.53
, pp. 2736-2739
-
-
Reifenberger, G.1
Liu, L.2
Ichimura, K.3
Schmidt, E.E.4
Collins, V.P.5
-
55
-
-
0027947609
-
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
-
Rhyu, M. S., L. Y. Jan, and Y. N. Jan. 1994. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76:477-491.
-
(1994)
Cell
, vol.76
, pp. 477-491
-
-
Rhyu, M.S.1
Jan, L.Y.2
Jan, Y.N.3
-
56
-
-
0032518917
-
Nucleocytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein
-
53a. Roth, J., M. Dobbelstein, D. A. Freedman, and A. J. Levine. 1998. Nucleocytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein. EMBO J. 17:554-564.
-
(1998)
EMBO J.
, vol.17
, pp. 554-564
-
-
Roth, J.1
Dobbelstein, M.2
Freedman, D.A.3
Levine, A.J.4
-
57
-
-
0030930853
-
Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module
-
Salcini, A. E., S. Confalonieri, M. Doria, E. Santolini, E. Tassi, O. Minenkova, G. Cesareni, P. G. Pelicci, and F. P. Di. 1997. Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. Genes Dev. 11:2239-2249.
-
(1997)
Genes Dev.
, vol.11
, pp. 2239-2249
-
-
Salcini, A.E.1
Confalonieri, S.2
Doria, M.3
Santolini, E.4
Tassi, E.5
Minenkova, O.6
Cesareni, G.7
Pelicci, P.G.8
Di, F.P.9
-
58
-
-
0030696331
-
Induction of Mdm2 and enhancement of cell survival by bFGF
-
Shaulian, E., D. Reznitzky, O. Shifman, G. Blandino, A. Amsterdam, A. Yayon, and M. Oren. 1997. Induction of Mdm2 and enhancement of cell survival by bFGF. Oncogene 15:2717-2725.
-
(1997)
Oncogene
, vol.15
, pp. 2717-2725
-
-
Shaulian, E.1
Reznitzky, D.2
Shifman, O.3
Blandino, G.4
Amsterdam, A.5
Yayon, A.6
Oren, M.7
-
59
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington, R., E. I. Rogaev, Y. Liang, E. A. Rogaeva, G. Levesque, M. Ikeda, H. Chi, C. Lin, G. Li, K. Holman, et al. 1995. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375:754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
-
61
-
-
0029824669
-
Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: Transforming ability and frequent detection in human cancer
-
Sigalas, I., A. H. Calvert, J. J. Anderson, D. E. Neal, and J. Lunec. 1996. Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer. Nat. Med. 2:912-917.
-
(1996)
Nat. Med.
, vol.2
, pp. 912-917
-
-
Sigalas, I.1
Calvert, A.H.2
Anderson, J.J.3
Neal, D.E.4
Lunec, J.5
-
62
-
-
0029010308
-
The phosphotyrosine interaction domain of SHC recognizes tyrosine phosphorylated NPXY motif
-
Songyang, Z., B. Margolis, M. Chaudhuri, S. E. Shoelson, and L. C. Cantley. 1995. The phosphotyrosine interaction domain of SHC recognizes tyrosine phosphorylated NPXY motif. J. Biol. Chem. 270:14863-14866.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 14863-14866
-
-
Songyang, Z.1
Margolis, B.2
Chaudhuri, M.3
Shoelson, S.E.4
Cantley, L.C.5
-
63
-
-
0030860911
-
Repression of p53-mediated transcription by MDM2: A dual mechanism
-
Thut, C. J., J. A. Goodrich, and R. Tjian. 1997. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev. 11:1974-1986.
-
(1997)
Genes Dev.
, vol.11
, pp. 1974-1986
-
-
Thut, C.J.1
Goodrich, J.A.2
Tjian, R.3
-
64
-
-
0024980213
-
numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
-
Uemura, T., S. Shepherd, L. Ackerman, L. Y. Jan, and Y. N. Jan. 1989. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58:349-360.
-
(1989)
Cell
, vol.58
, pp. 349-360
-
-
Uemura, T.1
Shepherd, S.2
Ackerman, L.3
Jan, L.Y.4
Jan, Y.N.5
-
65
-
-
0030250783
-
Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate
-
Verdi, J. M., R. Schmandt, A. Bashirullah, S. Jacob, R. Salvino, C. G. Craig, A. E. Program, H. D. Lipshitz, and C. J. McGlade. 1996. Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate. Curr. Biol. 6:1134-1145.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1134-1145
-
-
Verdi, J.M.1
Schmandt, R.2
Bashirullah, A.3
Jacob, S.4
Salvino, R.5
Craig, C.G.6
Program, A.E.7
Lipshitz, H.D.8
McGlade, C.J.9
-
66
-
-
0027244853
-
The p53-mdm-2 autoregulatory feedback loop
-
Wu, X., J. H. Bayle, D. Olson, and A. J. Levine. 1993. The p53-mdm-2 autoregulatory feedback loop. Genes Dev. 7:1126-1132.
-
(1993)
Genes Dev.
, vol.7
, pp. 1126-1132
-
-
Wu, X.1
Bayle, J.H.2
Olson, D.3
Levine, A.J.4
-
67
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein MDM2
-
Xiao Z., J. Chen, A. J. Levine, N. Modjtahedi, J. Xing, W. R. Sellers, and D. M. Livingston. 1995. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature 375:694-698.
-
(1995)
Nature
, vol.375
, pp. 694-698
-
-
Xiao, Z.1
Chen, J.2
Levine, A.J.3
Modjtahedi, N.4
Xing, J.5
Sellers, W.R.6
Livingston, D.M.7
-
68
-
-
0029131447
-
A functional p53-responsive intronic promoter is contained within the human mdm2 gene
-
Zauberman, A., D. Flusberg, Y. Haupt, Y. Barak, and M. Oren 1995. A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nucleic Acids Res. 23:2584-2592.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 2584-2592
-
-
Zauberman, A.1
Flusberg, D.2
Haupt, Y.3
Barak, Y.4
Oren, M.5
-
69
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
64a. Zhang, Y., Y. Xiong, and W. G. Yarbrough. 1998. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92:725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
70
-
-
0030200217
-
Assymetric localization of a mammalian Numb homolog during mouse cortical neurogenesis
-
Zhong, W., J. N. Feder, M. Jiang, L. Y. Jan, and Y. N. Jan. 1996. Assymetric localization of a mammalian Numb homolog during mouse cortical neurogenesis. Neuron 17:43-53.
-
(1996)
Neuron
, vol.17
, pp. 43-53
-
-
Zhong, W.1
Feder, J.N.2
Jiang, M.3
Jan, L.Y.4
Jan, Y.N.5
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