-
1
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25: 585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
2
-
-
0025472467
-
Telomeres, telomerase and senescence
-
Greider CW. Telomeres, telomerase and senescence. Bioessays 1990; 12: 363-369.
-
(1990)
Bioessays
, vol.12
, pp. 363-369
-
-
Greider, C.W.1
-
3
-
-
0025787643
-
Telomere loss: Mitotic clock or genetic time bomb?
-
Harley CB. Telomere loss: mitotic clock or genetic time bomb? Mutation Res 1991; 256: 271-282.
-
(1991)
Mutation Res
, vol.256
, pp. 271-282
-
-
Harley, C.B.1
-
4
-
-
0033996493
-
Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation
-
Krupp G, Klapper W, Parwaresch R. Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation. Cell Mol Life Sci 2000; 57: 464-486.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 464-486
-
-
Krupp, G.1
Klapper, W.2
Parwaresch, R.3
-
5
-
-
0034081874
-
Aging clock: The watchmaker's masterpiece
-
Ishikawa F. Aging clock: the watchmaker's masterpiece. Cell Mol Life Sci 2000; 57: 698-704.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 698-704
-
-
Ishikawa, F.1
-
6
-
-
0033957897
-
Telomeres, telomerase and myc. An update
-
Cerni C. Telomeres, telomerase and myc. An update. Mutat Res 2000; 462: 31-47.
-
(2000)
Mutat Res
, vol.462
, pp. 31-47
-
-
Cerni, C.1
-
7
-
-
0032907528
-
Cellular senescence and cancer
-
Wynford-Thomas D. Cellular senescence and cancer. J Pathol 1999; 187: 100-111.
-
(1999)
J Pathol
, vol.187
, pp. 100-111
-
-
Wynford-Thomas, D.1
-
8
-
-
0030657690
-
The restriction point and control of cell proliferation
-
Planas-Silva MD, Weinberg RA. The restriction point and control of cell proliferation. Curr Opin Cell Biol 1997; 9: 768-772.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 768-772
-
-
Planas-Silva, M.D.1
Weinberg, R.A.2
-
9
-
-
0030513456
-
The cell cycle-theory and application to cancer
-
Parwaresch R, Rudolph P. The cell cycle-theory and application to cancer. Oncologie 1996; 19: 464-472.
-
(1996)
Oncologie
, vol.19
, pp. 464-472
-
-
Parwaresch, R.1
Rudolph, P.2
-
10
-
-
0031710479
-
The INK4a/ARF tumor suppressor: One gene-two products-two pathways
-
Chin L, Pomerantz J, DePinho RA. The INK4a/ARF tumor suppressor: one gene-two products-two pathways. Trends Biochem Sci 1998; 23: 291-296.
-
(1998)
Trends Biochem Sci
, vol.23
, pp. 291-296
-
-
Chin, L.1
Pomerantz, J.2
DePinho, R.A.3
-
11
-
-
0029563009
-
Telomeres: Beginning to understand the end
-
Zakian V. Telomeres: Beginning to understand the end. Science 1995; 270: 1601-1607.
-
(1995)
Science
, vol.270
, pp. 1601-1607
-
-
Zakian, V.1
-
12
-
-
0031000884
-
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
-
Makarov VL, Hirose Y, Langmore JP. Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 1997; 88: 657-666.
-
(1997)
Cell
, vol.88
, pp. 657-666
-
-
Makarov, V.L.1
Hirose, Y.2
Langmore, J.P.3
-
13
-
-
0024325562
-
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
-
Morin GB. The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 1989; 59: 521-529.
-
(1989)
Cell
, vol.59
, pp. 521-529
-
-
Morin, G.B.1
-
14
-
-
0032765047
-
Studies of the molecular mechanisms in the regulation of telomerase activity
-
Liu J-P. Studies of the molecular mechanisms in the regulation of telomerase activity. FASEB J 1999; 13: 2091-2104.
-
(1999)
FASEB J
, vol.13
, pp. 2091-2104
-
-
Liu, J.-P.1
-
15
-
-
0028564951
-
Specific association of human telomerase activity with immortal cells and cancer
-
Kim NW, Piatyszec MA, Prowse KR et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011-2015.
-
(1994)
Science
, vol.266
, pp. 2011-2015
-
-
Kim, N.W.1
Piatyszec, M.A.2
Prowse, K.R.3
-
16
-
-
0025731583
-
Structure and function of telomeres
-
Blackburn EH. Structure and function of telomeres. Nature 1991; 350: 569-573.
-
(1991)
Nature
, vol.350
, pp. 569-573
-
-
Blackburn, E.H.1
-
17
-
-
0033553455
-
Telomeres do D-Loop-T-Loop
-
Greider CW. Telomeres do D-Loop-T-Loop. Cell 1999; 97: 419-422.
-
(1999)
Cell
, vol.97
, pp. 419-422
-
-
Greider, C.W.1
-
18
-
-
0031047642
-
Block in anaphase chromosome separation caused by a telomerase template mutation
-
Kirk KE, Harmon BP, Reichardt IK et al. Block in anaphase chromosome separation caused by a telomerase template mutation. Science 1997; 275: 1478-1481.
-
(1997)
Science
, vol.275
, pp. 1478-1481
-
-
Kirk, K.E.1
Harmon, B.P.2
Reichardt, I.K.3
-
19
-
-
0029894237
-
Telomere length regulation
-
Greider CW. Telomere length regulation. Annu Rev Biochem 1996; 65: 337-365.
-
(1996)
Annu Rev Biochem
, vol.65
, pp. 337-365
-
-
Greider, C.W.1
-
20
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn EH. Switching and signaling at the telomere. Cell 2001; 106: 661-673.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
21
-
-
0013462065
-
A highly conserved repetitive DNA sequence (TTAGGG)n, present at the telomeres of human chromosomes
-
Moyzis RK, Buckingham JM, Cram LS et al. A highly conserved repetitive DNA sequence (TTAGGG)n, present at the telomeres of human chromosomes. Proc Natl Acad Sci USA 1988; 85: 6622-6626.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6622-6626
-
-
Moyzis, R.K.1
Buckingham, J.M.2
Cram, L.S.3
-
22
-
-
0037148342
-
Telomeres, aging and cancer: In search of a happy ending
-
Kim S, Kaminker P, Campisi J, Telomeres, aging and cancer: In search of a happy ending. Oncogene 2002; 21: 503-511.
-
(2002)
Oncogene
, vol.21
, pp. 503-511
-
-
Kim, S.1
Kaminker, P.2
Campisi, J.3
-
23
-
-
0026085703
-
Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16
-
Wilkie AO, Higgs DR, Rack KA et al. Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16. Cell 1991; 64: 595-606.
-
(1991)
Cell
, vol.64
, pp. 595-606
-
-
Wilkie, A.O.1
Higgs, D.R.2
Rack, K.A.3
-
24
-
-
0019568388
-
All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′-terminus
-
Klobutcher LA, Swanton MT, Donini P, Prescott DM. All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3′-terminus. Proc Natl Acad Sci USA 1981; 78: 3015-3019.
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 3015-3019
-
-
Klobutcher, L.A.1
Swanton, M.T.2
Donini, P.3
Prescott, D.M.4
-
26
-
-
0032489012
-
TRF2 protects human telomeres from end-to-end fusion
-
van Steensel B, Smogorzewska A, de Lange T. TRF2 protects human telomeres from end-to-end fusion. Cell 1998; 92: 401-413.
-
(1998)
Cell
, vol.92
, pp. 401-413
-
-
Van Steensel, B.1
Smogorzewska, A.2
De Lange, T.3
-
27
-
-
0031036350
-
A mammalian telomerase-associated protein
-
Harrington L, McPhail T, Mar V et al. A mammalian telomerase-associated protein. Science 1997; 275: 973-977.
-
(1997)
Science
, vol.275
, pp. 973-977
-
-
Harrington, L.1
McPhail, T.2
Mar, V.3
-
28
-
-
0031800617
-
Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase
-
LaBranche H, Dupuis S, Ben-David Y et al. Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase. Nat Genet 1998; 19: 199-202.
-
(1998)
Nat Genet
, vol.19
, pp. 199-202
-
-
LaBranche, H.1
Dupuis, S.2
Ben-David, Y.3
-
29
-
-
0032553473
-
Tankyrase, a poly (ADP-ribose) polymerase at human telomeres
-
Smith S, Giriat I, Schmitt A, de Lange T. Tankyrase, a poly (ADP-ribose) polymerase at human telomeres. Science 1998; 282: 1484-1487.
-
(1998)
Science
, vol.282
, pp. 1484-1487
-
-
Smith, S.1
Giriat, I.2
Schmitt, A.3
De Lange, T.4
-
30
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CM. Telomeres shorten during ageing of human fibroblasts. Nature 1990; 345: 458-460.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.M.3
-
31
-
-
0037148271
-
Telomerase in the human organism
-
Collins K, Mitchell JR. Telomerase in the human organism. Oncogene 2002; 21: 564-579.
-
(2002)
Oncogene
, vol.21
, pp. 564-579
-
-
Collins, K.1
Mitchell, J.R.2
-
32
-
-
0031922795
-
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals
-
Iwama H, Ohyashiki K, Ohyashiki JH et al. Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Hum Genet 1998; 102: 397-402.
-
(1998)
Hum Genet
, vol.102
, pp. 397-402
-
-
Iwama, H.1
Ohyashiki, K.2
Ohyashiki, J.H.3
-
33
-
-
0023034140
-
Variability at the telomeres of the human X/Y pseudoautomosal region
-
Cooke HJ, Smith BA. Variability at the telomeres of the human X/Y pseudoautomosal region. Cold Spring Harbor Symp Quant Biol 1986; 51: 213-219.
-
(1986)
Cold Spring Harbor Symp Quant Biol
, vol.51
, pp. 213-219
-
-
Cooke, H.J.1
Smith, B.A.2
-
34
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie N, Dempster M, Dunlop M et al. Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990; 346: 866-868.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.1
Dempster, M.2
Dunlop, M.3
-
35
-
-
0033553536
-
Mammalian telomeres end in a large duplex loop
-
Griffith JD, Comeau L, Rosenfield S et al. Mammalian telomeres end in a large duplex loop. Cell 1999; 97: 503-514.
-
(1999)
Cell
, vol.97
, pp. 503-514
-
-
Griffith, J.D.1
Comeau, L.2
Rosenfield, S.3
-
37
-
-
0022402513
-
Identification of a specific telomere terminal transferase activity in Tetrahymena
-
Greider CW, Blackburn EH. Identification of a specific telomere terminal transferase activity in Tetrahymena. Cell 1985; 43: 405-413.
-
(1985)
Cell
, vol.43
, pp. 405-413
-
-
Greider, C.W.1
Blackburn, E.H.2
-
38
-
-
0023663881
-
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
-
Greider CW, Blackburn EH. The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity. Cell 1987; 51: 887-898.
-
(1987)
Cell
, vol.51
, pp. 887-898
-
-
Greider, C.W.1
Blackburn, E.H.2
-
39
-
-
0029096515
-
The RNA component of human telomerase
-
Feng J, Funk WD, Wang S-S et al. The RNA component of human telomerase. Science 1995; 269: 1236-1241.
-
(1995)
Science
, vol.269
, pp. 1236-1241
-
-
Feng, J.1
Funk, W.D.2
Wang, S.-S.3
-
40
-
-
0030668722
-
Human telomerase contains evolutionarily conserved catalytic and structural subunits
-
Harrington L, Zhou W, McPhail T. Human telomerase contains evolutionarily conserved catalytic and structural subunits. Genes Dev 1997; 11: 3109-3115.
-
(1997)
Genes Dev
, vol.11
, pp. 3109-3115
-
-
Harrington, L.1
Zhou, W.2
McPhail, T.3
-
41
-
-
0028990123
-
Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
-
Collins K, Kobayashi R, Greider CW. Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme. Cell 1995; 81: 677-686.
-
(1995)
Cell
, vol.81
, pp. 677-686
-
-
Collins, K.1
Kobayashi, R.2
Greider, C.W.3
-
42
-
-
0024978857
-
A telomeric sequence in the RNA of Tetrahymena telomerase is required for telomere repeat synthesis
-
Greider CW, Blackburn EH. A telomeric sequence in the RNA of Tetrahymena telomerase is required for telomere repeat synthesis. Nature 1989; 337: 331-337.
-
(1989)
Nature
, vol.337
, pp. 331-337
-
-
Greider, C.W.1
Blackburn, E.H.2
-
43
-
-
0029154735
-
Functional characterization and developmental regulation of mouse telomerase RNA
-
Blasco MA, Funk W, Villeponteau B, Greider CW. Functional characterization and developmental regulation of mouse telomerase RNA. Science 1995; 269: 1267-1270.
-
(1995)
Science
, vol.269
, pp. 1267-1270
-
-
Blasco, M.A.1
Funk, W.2
Villeponteau, B.3
Greider, C.W.4
-
44
-
-
0025279059
-
In vivo alteration of telomere sequences caused by mutated Tetrahymena telomerase RNAs
-
Yu GL, Bradley JD, Attardi LD. In vivo alteration of telomere sequences caused by mutated Tetrahymena telomerase RNAs. Nature 1990; 344: 126-132.
-
(1990)
Nature
, vol.344
, pp. 126-132
-
-
Yu, G.L.1
Bradley, J.D.2
Attardi, L.D.3
-
45
-
-
0030819894
-
Telomerase catalytic subunit homologs from fission yeast and human
-
Nakamura TM, Morin GB, Chapman KB et al. Telomerase catalytic subunit homologs from fission yeast and human. Science 1997; 277: 955-959.
-
(1997)
Science
, vol.277
, pp. 955-959
-
-
Nakamura, T.M.1
Morin, G.B.2
Chapman, K.B.3
-
46
-
-
0030938901
-
Reverse transcriptase motifs in the catalytic subunit of telomerase
-
Lingner J, Hughes TR, Shevchenko A et al. Reverse transcriptase motifs in the catalytic subunit of telomerase. Science 1997; 276: 561-567.
-
(1997)
Science
, vol.276
, pp. 561-567
-
-
Lingner, J.1
Hughes, T.R.2
Shevchenko, A.3
-
47
-
-
0027486026
-
Sequence-specific DNA primer effects on telomerase polymerization activity
-
Lee MS, Blackburn EH. Sequence-specific DNA primer effects on telomerase polymerization activity. Mol Cell Biol 1993; 13: 6586-6599.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6586-6599
-
-
Lee, M.S.1
Blackburn, E.H.2
-
48
-
-
0029895352
-
Processing of non-telomeric 3' ends by telomerase: Default template alignment and endonucleolytic cleavage
-
Melek M, Greene EC, Shippen DE. Processing of non-telomeric 3' ends by telomerase: default template alignment and endonucleolytic cleavage. Mol Cell Biol 1996; 16: 3437-3445.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 3437-3445
-
-
Melek, M.1
Greene, E.C.2
Shippen, D.E.3
-
49
-
-
0029091386
-
Activation of telomerase in human lymphocytes and haematopoietic progenitor cells
-
Hiyama K, Hirai Y, Kyoizumi S et al. Activation of telomerase in human lymphocytes and haematopoietic progenitor cells. J Immunol 1995; 155: 3711-3715.
-
(1995)
J Immunol
, vol.155
, pp. 3711-3715
-
-
Hiyama, K.1
Hirai, Y.2
Kyoizumi, S.3
-
50
-
-
0030010433
-
Detection of telomerase activity in malignant and nonmalignant skin conditions
-
Taylor RS, Ramirez RD, Ogoshi M et al. Detection of telomerase activity in malignant and nonmalignant skin conditions. J Invest Dermatol 1996; 106: 759-765.
-
(1996)
J Invest Dermatol
, vol.106
, pp. 759-765
-
-
Taylor, R.S.1
Ramirez, R.D.2
Ogoshi, M.3
-
51
-
-
0029829887
-
Telomerase activity in human intestine
-
Hiyama E, Hiyama K, Tatsumoto N et al. Telomerase activity in human intestine. Int J Oncol 1996; 9: 453-458.
-
(1996)
Int J Oncol
, vol.9
, pp. 453-458
-
-
Hiyama, E.1
Hiyama, K.2
Tatsumoto, N.3
-
52
-
-
0031036132
-
Telomerase activity concentrates in the mitotically active segments of human hair follicles
-
Ramirez RD, Wright WE, Shay JW, Taylor RS. Telomerase activity concentrates in the mitotically active segments of human hair follicles. J Invest Dermatol 1997; 108: 113-117.
-
(1997)
J Invest Dermatol
, vol.108
, pp. 113-117
-
-
Ramirez, R.D.1
Wright, W.E.2
Shay, J.W.3
Taylor, R.S.4
-
53
-
-
0030787753
-
Telomerase activity in benign endometrium and endometrial carcinoma
-
Brien TP, Kallakury BV, Lowry CV et al. Telomerase activity in benign endometrium and endometrial carcinoma. Cancer Res 1997; 57: 2760-2764.
-
(1997)
Cancer Res
, vol.57
, pp. 2760-2764
-
-
Brien, T.P.1
Kallakury, B.V.2
Lowry, C.V.3
-
54
-
-
0029748585
-
Telomeres and telomerase in human leukaemias
-
Shay JW, Werbin H, Wright WE. Telomeres and telomerase in human leukaemias. Leukemia 1996; 10: 1255-1261.
-
(1996)
Leukemia
, vol.10
, pp. 1255-1261
-
-
Shay, J.W.1
Werbin, H.2
Wright, W.E.3
-
55
-
-
0037148401
-
Regulation of the human telomerase reverse transcriptase gene
-
Ducrest A-L, Szutorisz H, Lingner J, Nabholz M. Regulation of the human telomerase reverse transcriptase gene. Oncogene 2002; 21: 541-552.
-
(2002)
Oncogene
, vol.21
, pp. 541-552
-
-
Ducrest, A.-L.1
Szutorisz, H.2
Lingner, J.3
Nabholz, M.4
-
56
-
-
0032962953
-
The human telomerase catalytic subunit hTERT: Organisation of the gene and characterization of the promoter
-
Cong YS, Wen J, Bacchetti S. The human telomerase catalytic subunit hTERT: organisation of the gene and characterization of the promoter. Hum Mol Genet 1999; 8: 137-142.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 137-142
-
-
Cong, Y.S.1
Wen, J.2
Bacchetti, S.3
-
57
-
-
2642610318
-
Myc activates telomerase
-
Wang J, Xie LY, Allan S et al. Myc activates telomerase. Genes Dev 1998; 12: 1769-1774.
-
(1998)
Genes Dev
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
-
58
-
-
0032911694
-
Direct activation of TERT transcription by c-myc
-
Wu KJ, Grandori C, Amacker M et al. Direct activation of TERT transcription by c-myc. Nat Genet 1999; 21: 220-224.
-
(1999)
Nat Genet
, vol.21
, pp. 220-224
-
-
Wu, K.J.1
Grandori, C.2
Amacker, M.3
-
59
-
-
0030008177
-
Telomerase activation by the E6 gene product of human papilloma-virus type 16
-
Klingelhutz AJ, Foster SA, McDougall JK. Telomerase activation by the E6 gene product of human papilloma-virus type 16. Nature 1996; 380: 79-82.
-
(1996)
Nature
, vol.380
, pp. 79-82
-
-
Klingelhutz, A.J.1
Foster, S.A.2
McDougall, J.K.3
-
60
-
-
0031763632
-
Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells
-
Burger AM, Fiebig HH, Kuettel MR et al. Effect of oncogene expression on telomerase activation and telomere length in human endothelial, fibroblast and prostate epithelial cells. Int J Oncol 1998; 13: 1043-1048.
-
(1998)
Int J Oncol
, vol.13
, pp. 1043-1048
-
-
Burger, A.M.1
Fiebig, H.H.2
Kuettel, M.R.3
-
61
-
-
0031846028
-
A human vascular endothelial cell model to study angiogenesis and tumorigenesis
-
Rhim JS, Tsai WP, Chen ZQ et al. A human vascular endothelial cell model to study angiogenesis and tumorigenesis. Carcinogenesis 1998; 19: 673-681.
-
(1998)
Carcinogenesis
, vol.19
, pp. 673-681
-
-
Rhim, J.S.1
Tsai, W.P.2
Chen, Z.Q.3
-
62
-
-
0031006856
-
Bcl-2 modulates telomerase activity
-
Mandal M, Kumar R. Bcl-2 modulates telomerase activity. J Biol Chem 1997; 272: 14183-14187.
-
(1997)
J Biol Chem
, vol.272
, pp. 14183-14187
-
-
Mandal, M.1
Kumar, R.2
-
63
-
-
9844232032
-
Reexpession of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition
-
Xu HJ, Zhou Y, Ji W et al. Reexpession of the retinoblastoma protein in tumor cells induces senescence and telomerase inhibition. Oncogene 1997; 15: 2589-2596.
-
(1997)
Oncogene
, vol.15
, pp. 2589-2596
-
-
Xu, H.J.1
Zhou, Y.2
Ji, W.3
-
64
-
-
0031933319
-
Growth arrest of immortalized human keratinocytes and suppression of telomerase activity by p21WAF1 gene expression
-
Kallassy M, Martel N, Damour O et al. Growth arrest of immortalized human keratinocytes and suppression of telomerase activity by p21WAF1 gene expression. Mol Carcinogen 1998; 21: 26-36.
-
(1998)
Mol Carcinogen
, vol.21
, pp. 26-36
-
-
Kallassy, M.1
Martel, N.2
Damour, O.3
-
65
-
-
0031027618
-
Control of telomere length by the human telomeric protein TRF1
-
van Steensel B, de Lange T. Control of telomere length by the human telomeric protein TRF1. Nature 1997; 385: 740-743.
-
(1997)
Nature
, vol.385
, pp. 740-743
-
-
Van Steensel, B.1
De Lange, T.2
-
66
-
-
0029013310
-
Absence of p53 allows direct immortalization of haematopoietic cells by the myc and raf oncogenes
-
Metz T, Harris AW, Adams JM. Absence of p53 allows direct immortalization of haematopoietic cells by the myc and raf oncogenes. Cell 1995; 82: 29-36.
-
(1995)
Cell
, vol.82
, pp. 29-36
-
-
Metz, T.1
Harris, A.W.2
Adams, J.M.3
-
67
-
-
0032509350
-
Telomerase is controlled by protein kinase C alpha in human breast cancer cells
-
Li H, Zhao L, Yang Z et al. Telomerase is controlled by protein kinase C alpha in human breast cancer cells. J Biol Chem 1998; 273: 33436-33442.
-
(1998)
J Biol Chem
, vol.273
, pp. 33436-33442
-
-
Li, H.1
Zhao, L.2
Yang, Z.3
-
68
-
-
0030755955
-
Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells
-
Li H, Zhao L, Funder JW, Liu J-P. Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells. J Biol Chem 1997; 272: 16729-16732.
-
(1997)
J Biol Chem
, vol.272
, pp. 16729-16732
-
-
Li, H.1
Zhao, L.2
Funder, J.W.3
Liu, J.-P.4
-
69
-
-
0033532056
-
Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
-
Kang SS, Kwon T, Kwon DY et al. Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit. J Biol Chem 1999; 274: 13085-13090.
-
(1999)
J Biol Chem
, vol.274
, pp. 13085-13090
-
-
Kang, S.S.1
Kwon, T.2
Kwon, D.Y.3
-
70
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco MA, Lee H-W, Hande MD et al. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 1997; 91: 25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.-W.2
Hande, M.D.3
-
71
-
-
0032499210
-
Essential role of mouse telomerase in highly proliferative organs
-
Lee HW, Blasco MA, Gottlieb GJ et al. Essential role of mouse telomerase in highly proliferative organs. Nature 1998; 392: 569-574.
-
(1998)
Nature
, vol.392
, pp. 569-574
-
-
Lee, H.W.1
Blasco, M.A.2
Gottlieb, G.J.3
-
72
-
-
0033525558
-
Longevity, stress response and cancer in aging telomerase-deficient mouse
-
Rudolph KL, Chang S, Lee HW et al. Longevity, stress response and cancer in aging telomerase-deficient mouse. Cell 1999; 96: 701-712.
-
(1999)
Cell
, vol.96
, pp. 701-712
-
-
Rudolph, K.L.1
Chang, S.2
Lee, H.W.3
-
73
-
-
0037148270
-
New ways not to make ends meet: Telomerase, DNA damage proteins and heterochromatin
-
Chan S W-L, Blackburn EH. New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin. Oncogene 2002; 21: 553-563.
-
(2002)
Oncogene
, vol.21
, pp. 553-563
-
-
Chan, S.W.-L.1
Blackburn, E.H.2
-
74
-
-
0033553516
-
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Chin L, Artandi SE, Shen Q et al. p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell 1999; 97: 527-538.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Chin, L.1
Artandi, S.E.2
Shen, Q.3
-
75
-
-
0029162563
-
Telomere elongation in immortal human cells without detectable telomerase activity
-
Bryan TM, Englezou A, Gupta J et al. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 1995; 14: 4240-4248.
-
(1995)
EMBO J
, vol.14
, pp. 4240-4248
-
-
Bryan, T.M.1
Englezou, A.2
Gupta, J.3
-
76
-
-
0030824031
-
Telomere maintenance without telomerase
-
Biessmann H, Mason JM. Telomere maintenance without telomerase. Chromosoma 1997; 106: 63-69.
-
(1997)
Chromosoma
, vol.106
, pp. 63-69
-
-
Biessmann, H.1
Mason, J.M.2
-
78
-
-
0028938262
-
Telomerase activity in normal leukocytes and in haematologic malignancies
-
Counter CM, Gupta J, Harley CB et al. Telomerase activity in normal leukocytes and in haematologic malignancies. Blood 1995; 85: 2315-2320.
-
(1995)
Blood
, vol.85
, pp. 2315-2320
-
-
Counter, C.M.1
Gupta, J.2
Harley, C.B.3
-
79
-
-
0028077099
-
Evidence for a mitotic clock in human haematopoietic stem cells: Loss of telomeric DNA with age
-
Vaziri H, Dragowska W, Allosopp RC et al. Evidence for a mitotic clock in human haematopoietic stem cells: loss of telomeric DNA with age. Proc Natl Acad Sci USA 1994; 91: 9857-9860.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9857-9860
-
-
Vaziri, H.1
Dragowska, W.2
Allosopp, R.C.3
-
80
-
-
0029937268
-
Telomerase activity in normal B-lymphocytes and non-Hodgkin's lymphomas
-
Norrback K-F, Dahlenborg K, Carlsson R, Roos G. Telomerase activity in normal B-lymphocytes and non-Hodgkin's lymphomas. Blood 1996; 88: 222-229.
-
(1996)
Blood
, vol.88
, pp. 222-229
-
-
Norrback, K.-F.1
Dahlenborg, K.2
Carlsson, R.3
Roos, G.4
-
81
-
-
0029894199
-
Regulated expression of telomerase activity in human T lymphocyte development and activation
-
Weng N-P, Levine BL, June CH, Hodes RJ. Regulated expression of telomerase activity in human T lymphocyte development and activation. J Exp Med 1996; 183: 2471-2479.
-
(1996)
J Exp Med
, vol.183
, pp. 2471-2479
-
-
Weng, N.-P.1
Levine, B.L.2
June, C.H.3
Hodes, R.J.4
-
82
-
-
0031202137
-
Telomerase is up-regulated in human germinal center B cells in vivo and can be re-expressed in memory B cells activated in vitro
-
Hu BT, Lee SC, Marin E et al. Telomerase is up-regulated in human germinal center B cells in vivo and can be re-expressed in memory B cells activated in vitro. J Immunol 1997; 159: 1068-1071.
-
(1997)
J Immunol
, vol.159
, pp. 1068-1071
-
-
Hu, B.T.1
Lee, S.C.2
Marin, E.3
-
83
-
-
0012950854
-
Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
-
Son NH, Murray S, Yanovski J et al. Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age. J Immunol 2000; 165: 1191-1196.
-
(2000)
J Immunol
, vol.165
, pp. 1191-1196
-
-
Son, N.H.1
Murray, S.2
Yanovski, J.3
-
85
-
-
0027956728
-
Telomerase activity in vivo in human malignant haematopoietic cells
-
Nilsson P, Mehle C, Remes K, Roos G. Telomerase activity in vivo in human malignant haematopoietic cells. Oncogene 1994; 9: 3043-3048.
-
(1994)
Oncogene
, vol.9
, pp. 3043-3048
-
-
Nilsson, P.1
Mehle, C.2
Remes, K.3
Roos, G.4
-
86
-
-
0032528448
-
Telomerase activity in Hodgkin's disease
-
Norrback K-F., Enblad G, Erlanson M et al. Telomerase activity in Hodgkin's disease. Blood 1998; 92: 567-573.
-
(1998)
Blood
, vol.92
, pp. 567-573
-
-
Norrback, K.-F.1
Enblad, G.2
Erlanson, M.3
-
87
-
-
0033967047
-
Telomerase activity in preleukaemia and acute myelogenous leukaemia
-
Li B, Yang J, Andrews C et al. Telomerase activity in preleukaemia and acute myelogenous leukaemia. Leuk Lymphoma 2000; 36: 579-587.
-
(2000)
Leuk Lymphoma
, vol.36
, pp. 579-587
-
-
Li, B.1
Yang, J.2
Andrews, C.3
-
88
-
-
0028340950
-
Telomere shortening associated with disease evolution patterns in myelodysplastic syndromes
-
Ohyashiki JH, Ohyashiki K, Fujimura T et al. Telomere shortening associated with disease evolution patterns in myelodysplastic syndromes. Cancer Res 1994; 54: 3557-3560.
-
(1994)
Cancer Res
, vol.54
, pp. 3557-3560
-
-
Ohyashiki, J.H.1
Ohyashiki, K.2
Fujimura, T.3
-
89
-
-
0033973802
-
Telomerase activity and telomere length in acute and chronic leukaemia, pre and post-ex vivo culture
-
Engelhardt M, Mackenzie K, Drullinsky P et al. Telomerase activity and telomere length in acute and chronic leukaemia, pre and post-ex vivo culture. Cancer Res 2000; 60: 610-617.
-
(2000)
Cancer Res
, vol.60
, pp. 610-617
-
-
Engelhardt, M.1
Mackenzie, K.2
Drullinsky, P.3
-
90
-
-
0033052012
-
Accelerated telomere shortening and telomerase activation in Fanconi's anaemia
-
Leteurtre F, Li X, Guardiola P et al. Accelerated telomere shortening and telomerase activation in Fanconi's anaemia. Br J of Haematol 1999; 105: 883-893.
-
(1999)
Br J of Haematol
, vol.105
, pp. 883-893
-
-
Leteurtre, F.1
Li, X.2
Guardiola, P.3
-
91
-
-
0030964322
-
Clinical implications of telomerase activity levels in acute leukaemia
-
Ohyashiki JH, Ohyashiki K, Iwama K et al. Clinical implications of telomerase activity levels in acute leukaemia. Clin Cancer Res 1997; 3: 619-625.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 619-625
-
-
Ohyashiki, J.H.1
Ohyashiki, K.2
Iwama, K.3
-
92
-
-
0029953160
-
Telomerase activity in human acute myelogenous leukaemia: Inhibition of telomerase activity by differentiation-inducing agents
-
Zhang W, Piatyszek MA, Kobayashi T et al. Telomerase activity in human acute myelogenous leukaemia: inhibition of telomerase activity by differentiation-inducing agents. Clin Cancer Res 1996; 2: 799-803.
-
(1996)
Clin Cancer Res
, vol.2
, pp. 799-803
-
-
Zhang, W.1
Piatyszek, M.A.2
Kobayashi, T.3
-
93
-
-
0031962410
-
Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy
-
Engelhardt M, Ozkaynak MF, Drullinsky P et al. Telomerase activity and telomere length in pediatric patients with malignancies undergoing chemotherapy. Leukemia 1998; 12: 13-24.
-
(1998)
Leukemia
, vol.12
, pp. 13-24
-
-
Engelhardt, M.1
Ozkaynak, M.F.2
Drullinsky, P.3
-
94
-
-
0031050032
-
Telomerase activity and cytogenetic changes in chronic myeloid leukaemia with disease progression
-
Ohyashiki K, Ohyashiki JH, Iwama S et al. Telomerase activity and cytogenetic changes in chronic myeloid leukaemia with disease progression. Leukemia 1997; 11: 190-194.
-
(1997)
Leukemia
, vol.11
, pp. 190-194
-
-
Ohyashiki, K.1
Ohyashiki, J.H.2
Iwama, S.3
-
95
-
-
0032855045
-
Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage
-
Trentin L, Ballon G, Ometto L et al. Telomerase activity in chronic lymphoproliferative disorders of B-cell lineage. Br J of Haematol 1999; 106: 662-668.
-
(1999)
Br J of Haematol
, vol.106
, pp. 662-668
-
-
Trentin, L.1
Ballon, G.2
Ometto, L.3
-
96
-
-
0033953479
-
Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse
-
Remes K, Norrback K-F, Rosenquist R et al. Telomere length and telomerase activity in malignant lymphomas at diagnosis and relapse. Br J of Cancer 2000; 82: 601-607.
-
(2000)
Br J of Cancer
, vol.82
, pp. 601-607
-
-
Remes, K.1
Norrback, K.-F.2
Rosenquist, R.3
-
97
-
-
0037148326
-
Clinical utility of telomerase in cancer
-
Hiyama E, Hiyama K. Clinical utility of telomerase in cancer. Oncogene 2002; 21: 643-649.
-
(2002)
Oncogene
, vol.21
, pp. 643-649
-
-
Hiyama, E.1
Hiyama, K.2
-
98
-
-
0030323040
-
Technical improvement in determining telomerase activity in haematologic neoplasias: A possibility of single cell determination of telomerase activity
-
Ohyashiki K, Ohyashiki JH, Toyama K. Technical improvement in determining telomerase activity in haematologic neoplasias: a possibility of single cell determination of telomerase activity. Hum Cell 1996; 9: 295-300.
-
(1996)
Hum Cell
, vol.9
, pp. 295-300
-
-
Ohyashiki, K.1
Ohyashiki, J.H.2
Toyama, K.3
-
99
-
-
0033455559
-
Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
-
Herbert B-S, Pitts AE, Baker SI et al. Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death. Proc Natl Acad Sci, 1999; 96: 14276-14281.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 14276-14281
-
-
Herbert, B.-S.1
Pitts, A.E.2
Baker, S.I.3
-
100
-
-
0029655485
-
Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines
-
Strahl C, Blackburn EH. Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Mol Cell Biol 1996; 16: 53-65.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 53-65
-
-
Strahl, C.1
Blackburn, E.H.2
-
101
-
-
0037148329
-
Telomerase inhibition, oligonucleotides and clinical trials
-
Corey RD. Telomerase inhibition, oligonucleotides and clinical trials. Oncogene 2002; 21: 631-637.
-
(2002)
Oncogene
, vol.21
, pp. 631-637
-
-
Corey, R.D.1
-
102
-
-
0031727943
-
G-quadruplex DNA: A target for drug design
-
Jean-Louis M, Claude H. G-quadruplex DNA: a target for drug design. Nat Med 1998; 4: 1366-1367.
-
(1998)
Nat Med
, vol.4
, pp. 1366-1367
-
-
Jean-Louis, M.1
Claude, H.2
-
103
-
-
0032539451
-
Accelerated telomere loss in young recipients of allogeneic bone-marrow transplants
-
Wynn RF, Cross MA, Hatton C et al. Accelerated telomere loss in young recipients of allogeneic bone-marrow transplants. Lancet 1998; 351: 178-181.
-
(1998)
Lancet
, vol.351
, pp. 178-181
-
-
Wynn, R.F.1
Cross, M.A.2
Hatton, C.3
-
104
-
-
0031962972
-
Changes of telomere length in children after haematopoietic stem cells transplantation
-
Akiyama M, Hoshi Y, Sakurai H et al. Changes of telomere length in children after haematopoietic stem cells transplantation. Bone Marrow Transplant 1998; 21: 167-171.
-
(1998)
Bone Marrow Transplant
, vol.21
, pp. 167-171
-
-
Akiyama, M.1
Hoshi, Y.2
Sakurai, H.3
-
105
-
-
0035863831
-
Accelerated telomere shortening in haematological lineages is limited to the first year following stem cell transplantation
-
Rufer N, Brummendorf TH, Chpuis B et al. Accelerated telomere shortening in haematological lineages is limited to the first year following stem cell transplantation. Blood 2001; 97: 575-577.
-
(2001)
Blood
, vol.97
, pp. 575-577
-
-
Rufer, N.1
Brummendorf, T.H.2
Chpuis, B.3
-
106
-
-
0033989539
-
Formation of functional tissue from transplanted adenocortical cells expresses telomerase reverse transcriptase
-
Thomas M, Yang L, Hornsby PJ. Formation of functional tissue from transplanted adenocortical cells expresses telomerase reverse transcriptase. Nat Biotechnol 2000; 18: 39-42.
-
(2000)
Nat Biotechnol
, vol.18
, pp. 39-42
-
-
Thomas, M.1
Yang, L.2
Hornsby, P.J.3
-
107
-
-
0029866564
-
The reactivation of telomerase activity in cancer progression
-
Shay JW, Wright WE. The reactivation of telomerase activity in cancer progression. Trends Genet 1996; 12: 129-131.
-
(1996)
Trends Genet
, vol.12
, pp. 129-131
-
-
Shay, J.W.1
Wright, W.E.2
|