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Volumn 19, Issue 6, 1996, Pages 464-472

The Cell Cycle – Theory and Application to Cancer

Author keywords

Cell cycle; Checkpoint; Cyclin; Cyclin dependent kinase; Cyclin kinase inhibitors; p53; Rb

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLINE; PROTEIN P53; RETINOBLASTOMA PROTEIN;

EID: 0030513456     PISSN: 22965270     EISSN: None     Source Type: Journal    
DOI: 10.1159/000218858     Document Type: Article
Times cited : (37)

References (82)
  • 1
    • 0028906240 scopus 로고
    • Cell proliferation kinetics of normal and tumour tissue in vitro: Quiescent reproductive cells and the cycling reproductive fraction
    • Baker FL, Sanger IJ, Rodgers RW, Jabboury K, Mangini OR: Cell proliferation kinetics of normal and tumour tissue in vitro: Quiescent reproductive cells and the cycling reproductive fraction, Cell Prolif 1995;28:1-15.
    • (1995) Cell Prolif , vol.28 , pp. 1-15
    • Baker, F.L.1    Sanger, I.J.2    Rodgers, R.W.3    Jabboury, K.4    Mangini, O.R.5
  • 2
    • 84990557416 scopus 로고
    • Origin and kinetics of resident tissue macrophages, Parabiosis studies with radiolabelled leucocytes
    • Parwaresch MR, Wackcr HH: Origin and kinetics of resident tissue macrophages, Parabiosis studies with radiolabelled leucocytes, Cell Tissue Kinet 1984:17: 25-39.
    • (1984) Cell Tissue Kinet , vol.17 , pp. 25-39
    • Parwaresch, M.R.1    Wackcr, H.H.2
  • 3
    • 0017099420 scopus 로고
    • Arndt D: 'Hie peripheral kinetics of human radio-labeled eosinophils
    • Parwaresch MR, Walle AJ, Arndt D: 'Hie peripheral kinetics of human radio-labeled eosinophils, Virchows Arch B Cell Pathol 1976:21:57-66.
    • (1976) Virchows Arch B Cell Pathol , vol.21 , pp. 57-66
    • Parwaresch, M.R.1    Walle, A.J.2
  • 4
    • 0018880062 scopus 로고
    • An unusual labeling index pattern of neutrophilic granulocytes after a 3H-thymidinc flash labeling injection
    • Parwaresch MR, Walle AJ, Voigt J: An unusual labeling index pattern of neutrophilic granulocytes after a 3H-thymidinc flash labeling injection, Virchows Arch B Cell Pathol 1980:33:177-185.
    • (1980) Virchows Arch B Cell Pathol , vol.33 , pp. 177-185
    • Parwaresch, M.R.1    Walle, A.J.2    Voigt, J.3
  • 5
    • 0028589378 scopus 로고
    • Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
    • Hall PA, Coates PJ, Ansari B, Hopwood D: Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis, J Cell Sci 1994;107:3569-3577.
    • (1994) J Cell Sci , vol.107 , pp. 3569-3577
    • Hall, P.A.1    Coates, P.J.2    Ansari, B.3    Hopwood, D.4
  • 6
    • 0028019173 scopus 로고
    • Genetics of growth arrest and cell death: Key determinants of tissue homeostasis
    • Hall PA, Lane DP: Genetics of growth arrest and cell death: Key determinants of tissue homeostasis, Fur J Cancer 1994;30A:2101-2112.
    • (1994) Fur J Cancer , vol.30A , pp. 2101-2112
    • Hall, P.A.1    Lane, D.P.2
  • 7
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • Harley CB: Telomere loss: Mitotic clock or genetic time bomb? Mutat Res 1991;256:271-282.
    • (1991) Mutat Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 8
    • 0027109075 scopus 로고
    • Cancer: P53. Guardian of the genome
    • Lane DP: Cancer: p53. guardian of the genome, Nature 1992358:15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 9
    • 0027934570 scopus 로고
    • DcPinho RA: P53-dependcnt apoptosis produced by Rb-defi-ciency in the developing mouse lens
    • Morgenbesser SD, Williams BO, Jacks T, DcPinho RA: p53-dependcnt apoptosis produced by Rb-defi-ciency in the developing mouse lens, Nature 1994:371:72-74.
    • (1994) Nature , vol.371 , pp. 72-74
    • Morgenbesser, S.D.1    Williams, B.O.2    Jacks, T.3
  • 10
    • 0028087776 scopus 로고
    • Tumour biology, p53. Guardian of Rb
    • White F,: Tumour biology, p53. guardian of Rb, Nature 1994:371:21-22.
    • (1994) Nature , vol.371 , pp. 21-22
    • White, F.1
  • 11
  • 12
    • 0026693966 scopus 로고
    • Animal cell cycles and their control
    • Norbury C, Nurse P: Animal cell cycles and their control, Annu Rev Biochem 1992:61:441-470.
    • (1992) Annu Rev Biochem , vol.61 , pp. 441-470
    • Norbury, C.1    Nurse, P.2
  • 13
    • 0025988705 scopus 로고
    • Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates
    • Norbury C, Blow J, Nurse P: Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates, EMBOJ 1991:10:3321-3329.
    • (1991) EMBOJ , vol.10 , pp. 3321-3329
    • Norbury, C.1    Blow, J.2    Nurse, P.3
  • 15
    • 0029051233 scopus 로고
    • Cyclin ubiquitination: The destructive end of mitosis
    • Murray A: Cyclin ubiquitination: The destructive end of mitosis, Cell 1995:81:149-152.
    • (1995) Cell , vol.81 , pp. 149-152
    • Murray, A.1
  • 16
    • 0028950016 scopus 로고
    • Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2
    • Desai D, Wesseling HC, Fisher RP, Morgan DO: Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2. Mol Cell Biol 1995:15:345-350.
    • (1995) Mol Cell Biol , vol.15 , pp. 345-350
    • Desai, D.1    Wesseling, H.C.2    Fisher, R.P.3    Morgan, D.O.4
  • 17
    • 0029007160 scopus 로고
    • A proliferative p53-respon-sivc element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeal
    • Gualberto A, Ilixon ML, Finco IS, Perkins ND, Nabel GJ, Baldwin ASI: A proliferative p53-respon-sivc element mediates tumor necrosis factor alpha induction of the human immunodeficiency virus type 1 long terminal repeal, Mol Cell Biol 1995:15: 3450-3459.
    • (1995) Mol Cell Biol , vol.15 , pp. 3450-3459
    • Gualberto, A.1    Ilixon, M.L.2    Finco, I.S.3    Perkins, N.D.4    Nabel, G.J.5    Baldwin, A.6
  • 18
    • 0025246110 scopus 로고
    • Universal control mechanism regulating the onset of M-phase
    • Nurse P: Universal control mechanism regulating the onset of M-phase, Nature 1990:344:503-508.
    • (1990) Nature , vol.344 , pp. 503-508
    • Nurse, P.1
  • 19
    • 0027007963 scopus 로고
    • Role of phosphorylation in p34cdc2 activation: Identification of an activating kinase
    • Solomon MJ, Lee T, Kirschner MW: Role of phosphorylation in p34cdc2 activation: Identification of an activating kinase, Mol Biol Cell 1992:3:13-27.
    • (1992) Mol Biol Cell , vol.3 , pp. 13-27
    • Solomon, M.J.1    Lee, T.2    Kirschner, M.W.3
  • 20
    • 0027585031 scopus 로고
    • Targets of cyclin-dependent protein kinases
    • Nigg EA: Targets of cyclin-dependent protein kinases, CurrOpin Cell Biol 1993:5:187-193.
    • (1993) Curropin Cell Biol , vol.5 , pp. 187-193
    • Nigg, E.A.1
  • 21
    • 0027336491 scopus 로고
    • Mammalian Gl cyclins
    • Sherr CJ: Mammalian Gl cyclins, Cell 1993:73: 1059-1065.
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 22
    • 0028171292 scopus 로고
    • Gl phase progression: Cycling on cue
    • Sherr CJ: Gl phase progression: Cycling on cue, Cell 1994;79:551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 23
    • 0028358931 scopus 로고
    • Cyclin E controls S phase progression and its down-regulaiion during Drosophila embryogenesis is required lor the arrest of cell pro lileration
    • Knoblich JA, Sauer K, Jones L, Richardson H, Saint R, Lehner CF: Cyclin E controls S phase progression and its down-regulaiion during Drosophila embryogenesis is required lor the arrest of cell pro lileration, Cell 1994:77:107-120.
    • (1994) Cell , vol.77 , pp. 107-120
    • Knoblich, J.A.1    Sauer, K.2    Jones, L.3    Richardson, H.4    Saint, R.5    Lehner, C.F.6
  • 24
    • 0026320075 scopus 로고
    • Cyclin A is required for the onset of DNA replication in mammalian fibroblasts
    • Girard F, Strausfeld IJ, Fernandez A, Lamb NJC: Cyclin A is required for the onset of DNA replication in mammalian fibroblasts, Cell 1991;67: 1169-1179.
    • (1991) Cell , vol.67 , pp. 1169-1179
    • Girard, F.1    Strausfeld, I.J.2    Fernandez, A.3    Lamb, N.4
  • 25
  • 26
    • 0028872607 scopus 로고
    • Differential regulation of E2F and Spl -mediated transcription by G1 cyclins
    • Shao Z, Robbins PD: Differential regulation of E2F and Spl -mediated transcription by G1 cyclins, Oncogene 1995:10:221-228.
    • (1995) Oncogene , vol.10 , pp. 221-228
    • Shao, Z.1    Robbins, P.D.2
  • 27
    • 0027944251 scopus 로고
    • Cyclin G is a transcriptional target of the p53 tumor suppressor protein
    • Okamoto K, Beach D: Cyclin G is a transcriptional target of the p53 tumor suppressor protein, EM BO J 1994;13:4816-4822.
    • (1994) EM BO J , vol.13 , pp. 4816-4822
    • Okamoto, K.1    Beach, D.2
  • 29
    • 0027426029 scopus 로고
    • A cdc2-related kinase PSSAI, RE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule
    • Kobayashi S, Ishiguro K, Omori A, Takamatsu M, Arioka M, Imahori K, IJchida T: A cdc2-related kinase PSSAI, RE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline-directed protein kinase associated with microtubule, FEBS Lett 1993:335:171-175.
    • (1993) FEBS Lett , vol.335 , pp. 171-175
    • Kobayashi, S.1    Ishiguro, K.2    Omori, A.3    Takamatsu, M.4    Arioka, M.5    Imahori, K.6    Ijchida, T.7
  • 30
    • 0028590113 scopus 로고
    • Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
    • Feaver WJ, Svejstrup JQ, Henry NL, Kornberg RD: Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK, Cell 1994: 79:1103-1109.
    • (1994) Cell , vol.79 , pp. 1103-1109
    • Feaver, W.J.1    Svejstrup, J.Q.2    Henry, N.L.3    Kornberg, R.D.4
  • 32
    • 0027938209 scopus 로고
    • Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
    • Hunter R, Pines J: Cyclins and cancer II: Cyclin D and CDK inhibitors come of age, Cell 1994:79: 573-582.
    • (1994) Cell , vol.79 , pp. 573-582
    • Hunter, R.1    Pines, J.2
  • 35
    • 0028899480 scopus 로고
    • Separate domains of p2l involved in the inhibition of Cdk kinase and PCNA
    • Chen J, Jackson PK, Kirschner MW, Dutta A: Separate domains of p2l involved in the inhibition of Cdk kinase and PCNA, Nature 1995:374:386-389.
    • (1995) Nature , vol.374 , pp. 386-389
    • Chen, J.1    Jackson, P.K.2    Kirschner, M.W.3    Dutta, A.4
  • 36
    • 0026619053 scopus 로고
    • The complexities of proliferatingcell nuclear antigen
    • McCormick D, Hall PA: The complexities of proliferatingcell nuclear antigen, Histopathology 1992: 21:591-594.
    • (1992) Histopathology , vol.21 , pp. 591-594
    • McCormick, D.1    Hall, P.A.2
  • 37
    • 0028176483 scopus 로고
    • Cloning of p27Kipl, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimilogenic signals
    • Polyak K, Lee MH, Erdjument Bromage H, Koff A, Roberts JM, Tempst P, Massaguc J: Cloning of p27Kipl, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimilogenic signals, Cell 1994:78:59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument Bromage, H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6    Massaguc, J.7
  • 38
    • 0028988158 scopus 로고
    • Cloning of p57KIP2. A cyclin-dcpendent kinase inhibitor with unique domain structure and tissue distribution
    • Lee MH, Reynisdottir I, Massaguc J: Cloning of p57KIP2. a cyclin-dcpendent kinase inhibitor with unique domain structure and tissue distribution, Genes Dev 1995:9:639-649.
    • (1995) Genes Dev , vol.9 , pp. 639-649
    • Lee, M.H.1    Reynisdottir, I.2    Massaguc, J.3
  • 39
    • 0028988159 scopus 로고
    • Elledge SJ: P57KIP2. A structurally distrinct member of the p21C1P1 Cdk inhibitor family, is a candidate tumor suppressor gene
    • Matsuoka S, Edwards MC, Bai C, Parker S, Zhang P, Baldini A, Harper JW, Elledge SJ: p57KIP2. a structurally distrinct member of the p21C1P1 Cdk inhibitor family, is a candidate tumor suppressor gene, Genes Dev 1995:9:650-662.
    • (1995) Genes Dev , vol.9 , pp. 650-662
    • Matsuoka, S.1    Edwards, M.C.2    Bai, C.3    Parker, S.4    Zhang, P.5    Baldini, A.6    Harper, J.W.7
  • 40
    • 0028582034 scopus 로고
    • Growth suppression by pis, a pl6INK4/, MTSI- and p 141NK4B/M rS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • Guan KL, Jenkins CW, Li Y, Nichols MA, Wu X, O'Keefe CL, Matera AG, Xiong Y: Growth suppression by pis, a pl6INK4/, MTSI- and p 141NK4B/M rS2-related CDK6 inhibitor, correlates with wild-type pRb function, Genes Dev 1994:8:2939-2952.
    • (1994) Genes Dev , vol.8 , pp. 2939-2952
    • Guan, K.L.1    Jenkins, C.W.2    Li, Y.3    Nichols, M.A.4    Wu, X.5    O'keefe, C.L.6    Matera, A.G.7    Xiong, Y.8
  • 41
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p!9 and pl8. Are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • Hirai H, Roussel ME Kato JY, Ashmun RA, Sherr CJ: Novel INK4 proteins, p!9 and pl8. are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol Cell Biol 1995:15:2672-2681.
    • (1995) Mol Cell Biol , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.E.2    Kato, J.Y.3    Ashmun, R.A.4    Sherr, C.J.5
  • 43
    • 0024425887 scopus 로고
    • Checkpoints: Controls that ensure the order of cell cycle events
    • Hartwell LH, Weinert TA: Checkpoints: Controls that ensure the order of cell cycle events, Science 1989:246:629-634.
    • (1989) Science , vol.246 , pp. 629-634
    • Hartwell, L.H.1    Weinert, T.A.2
  • 44
    • 0028009849 scopus 로고
    • The cell cycle and the retinoblastoma protein family
    • Ewen ME: The cell cycle and the retinoblastoma protein family, Cancer Metastasis Rev 1994:13: 45-66.
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 45-66
    • Ewen, M.E.1
  • 45
    • 0028204538 scopus 로고
    • The 1993 Walter Hubert Lecture: The role of the p53 tumour-suppressor gene in lumorigenesis
    • Levine AJ, Perry ME, Chang A, Silver A, Dittmer D, Wu M, Welsh D: The 1993 Walter Hubert Lecture: The role of the p53 tumour-suppressor gene in lumorigenesis, Br J Cancer 1994;69:409-416.
    • (1994) Br J Cancer , vol.69 , pp. 409-416
    • Levine, A.J.1    Perry, M.E.2    Chang, A.3    Silver, A.4    Dittmer, D.5    Wu, M.6    Welsh, D.7
  • 46
    • 0027447696 scopus 로고
    • Tumor-suppressor p53 and the cell cycle
    • Perry ME, Levine AJ: Tumor-suppressor p53 and the cell cycle, Curr Opin Genet Dev 1993;3:50-54.
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 50-54
    • Perry, M.E.1    Levine, A.J.2
  • 47
    • 0028175990 scopus 로고
    • The p53-dependent gamma-ray response of GADD45
    • Zhan Q, Bae I, Kastan MB, Fornace AJJ: The p53-dependent gamma-ray response of GADD45. Cancer Res 1994:54:2755-2760.
    • (1994) Cancer Res , vol.54 , pp. 2755-2760
    • Zhan, Q.1    Bae, I.2    Kastan, M.B.3    Fornace, A.4
  • 51
    • 0028872743 scopus 로고
    • Mitotic forces control a ccll-cycle checkpoint
    • Li X, Nicklas RB: Mitotic forces control a ccll-cycle checkpoint, Nature 1995:373:630-632.
    • (1995) Nature , vol.373 , pp. 630-632
    • Li, X.1    Nicklas, R.B.2
  • 53
    • 0028171096 scopus 로고
    • Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells
    • Andreasscn PR, Margolis RL: Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells, J Cell Biol 1994:127:789-802.
    • (1994) J Cell Biol , vol.127 , pp. 789-802
    • Reasscn, P.R.1    Margolis, R.L.2
  • 54
    • 0028891783 scopus 로고
    • Apoptosis, oncosis, and necrosis, An overview of cell death
    • Majno G, Joris I: Apoptosis, oncosis, and necrosis, An overview of cell death, Am J Pathol 1995:146: 3-15.
    • (1995) Am J Pathol , vol.146 , pp. 3-15
    • Majno, G.1    Joris, I.2
  • 55
    • 0028326952 scopus 로고
    • An evolutionary perspective of apoptosis
    • Vaux DL, Haecker G, Strasser A: An evolutionary perspective of apoptosis, Cell 1994:76:777-779.
    • (1994) Cell , vol.76 , pp. 777-779
    • Vaux, D.L.1    Haecker, G.2    Strasser, A.3
  • 56
  • 58
    • 0027302720 scopus 로고
    • Barrett's esophagus: Cell cycle abnormalities in advancing stages of neoplastic progression
    • Reid BJ, Sanchez CA, Blount PL, Levine DS: Barrett's esophagus: Cell cycle abnormalities in advancing stages of neoplastic progression, Gastroenterology 1993:105:119-129.
    • (1993) Gastroenterology , vol.105 , pp. 119-129
    • Reid, B.J.1    Sanchez, C.A.2    Blount, P.L.3    Levine, D.S.4
  • 59
    • 0025129170 scopus 로고
    • The clinical assessment of proliferation and growth in human tumours: Evaluation of methods and applications as prognostic variables
    • Quinn CM, Wright NA: The clinical assessment of proliferation and growth in human tumours: Evaluation of methods and applications as prognostic variables, J Pathol 1990:160:93-102.
    • (1990) J Pathol , vol.160 , pp. 93-102
    • Quinn, C.M.1    Wright, N.A.2
  • 60
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H: Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984:133: 1710-1715.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 61
    • 0025810796 scopus 로고
    • Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67
    • Gerdes J, Li L, Schluter C, Cuchrow M, Wohlenberg C, Gerlach C, Stahmer I, Kloth S, Brandt E, Flad H-D: Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 1991:138:867-873.
    • (1991) Am J Pathol , vol.138 , pp. 867-873
    • Gerdes, J.1    Li, L.2    Schluter, C.3    Cuchrow, M.4    Wohlenberg, C.5    Gerlach, C.6    Stahmer, I.7    Kloth, S.8    Brandt, E.9    Flad, H.-D.10
  • 62
    • 0027361196 scopus 로고
    • The cell proliferation-associated antigen of antibody Ki-67: A very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins
    • Schlüter C, Duchrow M, Wohlenberg C, Becker MUG, Key G, Flad H-D, Gerdes J: The cell proliferation-associated antigen of antibody Ki-67: A very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins, J Cell Biol 1993:123: 513-522.
    • (1993) J Cell Biol , vol.123 , pp. 513-522
    • Schlüter, C.1    Duchrow, M.2    Wohlenberg, C.3    Becker, M.4    Key, G.5    Flad, H.-D.6    Gerdes, J.7
  • 63
    • 0028167518 scopus 로고
    • The labeling of proliferating cells by Ki67 and Mib-1 antibodies depends on the binding of a nuclear protein to the DNA
    • Lopez F, Belloc F, Lacombe F, Dumain P, Feiffers J, Bernard P, Boisseau MR: The labeling of proliferating cells by Ki67 and Mib-1 antibodies depends on the binding of a nuclear protein to the DNA, Exp Cell Res 1994:210:145-153.
    • (1994) Exp Cell Res , vol.210 , pp. 145-153
    • Lopez, F.1    Belloc, F.2    Lacombe, F.3    Dumain, P.4    Feiffers, J.5    Bernard, P.6    Boisseau, M.R.7
  • 64
    • 0027163046 scopus 로고
    • Little missed markers and Ki-67
    • Schwarting R: Little missed markers and Ki-67. Lab Invest 1993:68:597-599.
    • (1993) Lab Invest , vol.68 , pp. 597-599
    • Schwarting, R.1
  • 65
    • 0027265154 scopus 로고
    • New Ki-67-equiva-lent murine monoclonal antibodies (MIB 1-3) generated against bacteriallv expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope
    • Key G, Becker MHG, Baron B, Duchrow M, Schluter C, Flad II-D, Gerdes J: New Ki-67-equiva-lent murine monoclonal antibodies (MIB 1-3) generated against bacteriallv expressed parts of the Ki-67 cDNA containing three 62 base pair repetitive elements encoding for the Ki-67 epitope, Lab Invest 1993:68:629-636.
    • (1993) Lab Invest , vol.68 , pp. 629-636
    • Key, G.1    Becker, M.2    Baron, B.3    Duchrow, M.4    Schluter, C.5    Flad, I.-D.6    Gerdes, J.7
  • 66
    • 0027771382 scopus 로고
    • Hauberg M, Tiemann M, Parwaresch R: Determination of the growth fraction in non-Hodgkin's lymphomas by monoclonal antibody Ki-S5 directed against a formalin-resistant epitope of the Ki-67 antigen
    • Kreipe H, Wacker HH, Heidebrecht HJ, Haas K, Hauberg M, Tiemann M, Parwaresch R: Determination of the growth fraction in non-Hodgkin's lymphomas by monoclonal antibody Ki-S5 directed against a formalin-resistant epitope of the Ki-67 antigen, Am J Pathol 1993:142:1689-1694.
    • (1993) Am J Pathol , vol.142 , pp. 1689-1694
    • Kreipe, H.1    Wacker, H.H.2    Heidebrecht, H.J.3    Haas, K.4
  • 67
    • 0028793582 scopus 로고
    • Diagnostic assessment of two novel proliferation-specific antigens in benign and malignant melanocytic lesions
    • Rudolph P, Lappe T, Schubert C, Schmidt D, Parwaresch RM, Christophers E: Diagnostic assessment of two novel proliferation-specific antigens in benign and malignant melanocytic lesions, Am J Pathol 1995:147:1615-1625.
    • (1995) Am J Pathol , vol.147 , pp. 1615-1625
    • Rudolph, P.1    Lappe, T.2    Schubert, C.3    Schmidt, D.4    Parwaresch, R.M.5    Christophers, E.6
  • 68
    • 0027830543 scopus 로고
    • Assessment of the growth fraction in prostate cancer by means of the nuclear proliferation associated formalin-resistant antigen Ki-S5
    • Rudolph P, Lappe T, Kreipe H, Parwaresch MR, Schmidt D: Assessment of the growth fraction in prostate cancer by means of the nuclear proliferation associated formalin-resistant antigen Ki-S5. Verh Dtsch C, es Pathol 1993;77:98-102.
    • (1993) Verh Dtsch C, Es Pathol , vol.77 , pp. 98-102
    • Rudolph, P.1    Lappe, T.2    Kreipe, H.3    Parwaresch, M.R.4    Schmidt, D.5
  • 71
    • 0025275171 scopus 로고
    • Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA), Structural conservation and the detection of a nucleolar form
    • Waseem NH, Lane DP: Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA), Structural conservation and the detection of a nucleolar form, J Cell Sci 1990;96:121-129.
    • (1990) J Cell Sci , vol.96 , pp. 121-129
    • Waseem, N.H.1    Lane, D.P.2
  • 72
    • 0027761101 scopus 로고
    • Comparison of three cell cycle associated antigens as markers of proliferative activity and prognosis in breast carcinoma
    • Gillett CE, Barnes DM, Camplejohn RS: Comparison of three cell cycle associated antigens as markers of proliferative activity and prognosis in breast carcinoma, J Clin Pathol 1993:46:1126-1128.
    • (1993) J Clin Pathol , vol.46 , pp. 1126-1128
    • Gillett, C.E.1    Barnes, D.M.2    Camplejohn, R.S.3
  • 73
    • 0025219285 scopus 로고    scopus 로고
    • Review: Assessment of cell proliferation in histological material
    • Hall PA, Levison DA: Review: Assessment of cell proliferation in histological material, J Clin Pathol 1999:43:184-192.
    • (1999) J Clin Pathol , vol.43 , pp. 184-192
    • Hall, P.A.1    Levison, D.A.2
  • 74
    • 0022896243 scopus 로고
    • Topoisomerase II: A specific marker for cell proliferation
    • Heck MMS, Earnshaw WC: Topoisomerase II: A specific marker for cell proliferation, J Cell Biol 1986:103:2569-2581.
    • (1986) J Cell Biol , vol.103 , pp. 2569-2581
    • Heck, M.1    Earnshaw, W.C.2
  • 75
    • 0027160745 scopus 로고
    • Molecular cloning of partial cDNAs for rat DNA topoisomerase II isoforms and their differential expression in brain development
    • Tsutsui K, Okada S, Watanabe M, Shohmori T, Seki S, Inoue Y: Molecular cloning of partial cDNAs for rat DNA topoisomerase II isoforms and their differential expression in brain development, J Biol Chem 1993:268:19076-19083.
    • (1993) J Biol Chem , vol.268 , pp. 19076-19083
    • Tsutsui, K.1    Okada, S.2    Watanabe, M.3    Shohmori, T.4    Seki, S.5    Inoue, Y.6
  • 80
    • 0025829609 scopus 로고
    • Antigen retrieval in formalin-fixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections
    • Shi S-R, Key ME, Kalra KL: Antigen retrieval in formalin-fixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections, J Histochem Cytochem 1991;39:741-748.
    • (1991) J Histochem Cytochem , vol.39 , pp. 741-748
    • Shi, S.-R.1    Key, M.E.2    Kalra, K.L.3
  • 81
    • 0027135951 scopus 로고
    • Update on proliferation-associated antibodies applicable to formalin-fixed paraffin-embedded tissue and their clinical applications
    • Yu CC-W, Filipe MI: Update on proliferation-associated antibodies applicable to formalin-fixed paraffin-embedded tissue and their clinical applications, Histochem J 1993 25:843-853.
    • (1993) Histochem J , vol.25 , pp. 843-853
    • Yu, C.-W.1    Filipe, M.I.2
  • 82
    • 0027463825 scopus 로고
    • Prognostic significance of a formalin-resistant nuclear proliferation antigen in mammary carcinomas as determined by the monoclonal antibody Ki-Sl
    • Kreipe H, Aim P, Olsson H, Hauberg M, Fischer L, Parwaresch R: Prognostic significance of a formalin-resistant nuclear proliferation antigen in mammary carcinomas as determined by the monoclonal antibody Ki-Sl, Am J Pathol 1993:142:651-657.
    • (1993) Am J Pathol , vol.142 , pp. 651-657
    • Kreipe, H.1    Aim, P.2    Olsson, H.3    Hauberg, M.4    Fischer, L.5    Parwaresch, R.6


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