15-Deoxy-Δ12,14-prostaglandin J2 and Thiazolidinediones Activate the MEK/ERK Pathway through Phosphatidylinositol 3-Kinase in Vascular Smooth Muscle Cells

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 48950-48955

  Takeda, Kotaro ^a   Ichiki, Toshihiro ^a   Tokunou, Tomotake ^a   Iino, Naoko ^a   Takeshita, Akira ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; ELECTROPHORESIS; ENZYME INHIBITION; MUSCLE; RNA;

LIGANDS;

ENZYMES;

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; BEZAFIBRATE; DNA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 3 KINASE; PIOGLITAZONE; PROTEIN KINASE B; RIBOSOME RNA; RNA 18S; THYMIDINE; TRITIUM; TROGLITAZONE; UNCLASSIFIED DRUG; UO 126; WORTMANNIN; 15 DEOXY 12,14 PROSTAGLANDIN J2; 15-DEOXY-12,14-PROSTAGLANDIN J2; ANDROSTANE DERIVATIVE; BIOLOGICAL RESPONSE MODIFIER; CELL RECEPTOR; CHROMAN DERIVATIVE; DRUG DERIVATIVE; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASES; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PROSTAGLANDIN D2; PROTEIN C FOS; PROTO ONCOGENE PROTEINS C FOS; THIAZOLE DERIVATIVE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR EFFECT; DNA SYNTHESIS; DRUG EFFECT; ENZYME ACTIVATION; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; THORACIC AORTA; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG POTENTIATION; ENZYMOLOGY; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RAT STRAIN; SIGNAL TRANSDUCTION;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMAL; BIOLOGICAL RESPONSE MODIFIERS; CELLS, CULTURED; CHROMANS; ENZYME ACTIVATION; ENZYME INHIBITORS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PHOSPHORYLATION; PROSTAGLANDIN D2; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; THIAZOLES; THYMIDINE; TRANSCRIPTION FACTORS;

EID: 0035966105     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108722200     Document Type: Article

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