-
1
-
-
0030666222
-
Innate immunity: The virtues of a nonclonal system of recognition
-
Medzhitov R., Janeway C.A. Jr. Innate immunity: the virtues of a nonclonal system of recognition. Cell. 91:1997;295-298.
-
(1997)
Cell
, vol.91
, pp. 295-298
-
-
Medzhitov, R.1
Janeway C.A., Jr.2
-
2
-
-
0034680145
-
Toll-like receptors in the induction of the innate immune response
-
Aderem A., Ulevitch R.J. Toll-like receptors in the induction of the innate immune response. Nature. 406:2000;782-787.
-
(2000)
Nature
, vol.406
, pp. 782-787
-
-
Aderem, A.1
Ulevitch, R.J.2
-
3
-
-
0036069958
-
Genetic approaches to the study of Toll-like receptor function
-
Takeuchi O., Akira S. Genetic approaches to the study of Toll-like receptor function. Microbes Infect. 4:2002;887-895.
-
(2002)
Microbes Infect.
, vol.4
, pp. 887-895
-
-
Takeuchi, O.1
Akira, S.2
-
4
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R., Preston-Hurlburt P., Janeway C.A. Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 388:1997;394-397.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway C.A., Jr.3
-
6
-
-
0032526861
-
The human Toll signaling pathway: Divergence of nuclear factor κ B and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6)
-
Muzio M., Natoli G., Saccani S., Levrero M., Mantovani A. The human Toll signaling pathway: divergence of nuclear factor. κ B and JNK/SAPK activation upstream of tumor necrosis factor receptor-associated factor 6 (TRAF6) J. Exp. Med. 187:1998;2097-2101.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 2097-2101
-
-
Muzio, M.1
Natoli, G.2
Saccani, S.3
Levrero, M.4
Mantovani, A.5
-
7
-
-
0032133278
-
MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
-
Medzhitov R., Preston-Hurlburt P., Kopp E., Stadlen A., Chen C., Ghosh S., Janeway C.A. Jr. MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol. Cell. 2:1998;253-258.
-
(1998)
Mol. Cell
, vol.2
, pp. 253-258
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Kopp, E.3
Stadlen, A.4
Chen, C.5
Ghosh, S.6
Janeway C.A., Jr.7
-
8
-
-
0033952268
-
TAK1 mediates an activation signal from Toll-like receptor(s) to nuclear factor- κ B in lipopolysaccharide-stimulated macrophages
-
Irie T., Muta T., Takeshige K. TAK1 mediates an activation signal from Toll-like receptor(s) to nuclear factor-. κ B in lipopolysaccharide-stimulated macrophages FEBS Lett. 467:2000;160-164.
-
(2000)
FEBS Lett.
, vol.467
, pp. 160-164
-
-
Irie, T.1
Muta, T.2
Takeshige, K.3
-
9
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF- κB activity
-
Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-. κB activity Annu. Rev. Immunol. 18:2000;621-663.
-
(2000)
Annu. Rev. Immunol.
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
10
-
-
0033596121
-
Activators and target genes of Rel/NF- κB transcription factors
-
Pahl H.L. Activators and target genes of Rel/NF-. κB transcription factors Oncogene. 18:1999;6853-6866.
-
(1999)
Oncogene
, vol.18
, pp. 6853-6866
-
-
Pahl, H.L.1
-
11
-
-
0035920176
-
A novel IκB protein, Iκ B- ζ, induced by proinflammatory stimuli, negatively regulates nuclear factor- κ B in the nuclei
-
Yamazaki S., Muta T., Takeshige K. A novel. IκB protein, Iκ B- ζ, induced by proinflammatory stimuli, negatively regulates nuclear factor- κ B in the nuclei J. Biol. Chem. 276:2001;27657-27662.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27657-27662
-
-
Yamazaki, S.1
Muta, T.2
Takeshige, K.3
-
12
-
-
0031017618
-
MAP3K-related kinase involved in NF- κB induction by TNF, CD95 and IL-1
-
Malinin N.L., Boldin M.P., Kovalenko A.V., Wallach D. MAP3K-related kinase involved in NF-. κB induction by TNF, CD95 and IL-1 Nature. 385:1997;540-544.
-
(1997)
Nature
, vol.385
, pp. 540-544
-
-
Malinin, N.L.1
Boldin, M.P.2
Kovalenko, A.V.3
Wallach, D.4
-
13
-
-
0030611595
-
IκB kinase- β: NF- κB activation and complex formation with IκB kinase- α and NIK
-
Woronicz J.D., Gao X., Cao Z., Rothe M., Goeddel D.V. IκB kinase- β: NF- κB activation and complex formation with IκB kinase- α and NIK Science. 278:1997;866-869.
-
(1997)
Science
, vol.278
, pp. 866-869
-
-
Woronicz, J.D.1
Gao, X.2
Cao, Z.3
Rothe, M.4
Goeddel, D.V.5
-
14
-
-
0034819316
-
Essential roles of CD14 and lipopolysaccharide-binding protein for activation of Toll-like receptor (TLR)2 as well as TLR4. Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations
-
Muta T., Takeshige K. Essential roles of CD14 and lipopolysaccharide-binding protein for activation of Toll-like receptor (TLR)2 as well as TLR4. Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations. Eur. J. Biochem. 268:2001;4580-4589.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 4580-4589
-
-
Muta, T.1
Takeshige, K.2
-
15
-
-
0034283837
-
The Rel/NF- κB family: Friend and foe
-
Perkins N.D. The Rel/NF-. κB family: friend and foe Trends Biochem. Sci. 25:2000;434-440.
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 434-440
-
-
Perkins, N.D.1
-
16
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald K.A., Palsson-McDermott E.M., Bowie A.G., Jefferies C.A., Mansell A.S., Brady G., Brint E., Dunne A., Gray P., Harte M.T., McMurray D., Smith D.E., Sims J.E., Bird T.A., O'Neill L.A.J. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature. 413:2001;78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
McMurray, D.11
Smith, D.E.12
Sims, J.E.13
Bird, T.A.14
O'Neill, L.A.J.15
-
17
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng T., Barton G.M., Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2:2001;835-841.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
18
-
-
0037084504
-
All TRAFs are not created equal: Common and distinct molecular mechanisms of TRAF-mediated signal transduction
-
Chung J.Y., Park Y.C., Ye H., Wu H. All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J. Cell Sci. 115:2002;679-688.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 679-688
-
-
Chung, J.Y.1
Park, Y.C.2
Ye, H.3
Wu, H.4
-
19
-
-
0032930861
-
Alymphoplasia is caused by a point mutation in the mouse gene encoding NF- κ B-inducing kinase
-
Shinkura R., Kitada K., Matsuda F., Tashiro K., Ikuta K., Suzuki M., Kogishi K., Serikawa T., Honjo T. Alymphoplasia is caused by a point mutation in the mouse gene encoding NF-. κ B-inducing kinase Nat. Genet. 22:1999;74-77.
-
(1999)
Nat. Genet.
, vol.22
, pp. 74-77
-
-
Shinkura, R.1
Kitada, K.2
Matsuda, F.3
Tashiro, K.4
Ikuta, K.5
Suzuki, M.6
Kogishi, K.7
Serikawa, T.8
Honjo, T.9
-
20
-
-
0035896422
-
Defective lymphotoxin- β receptor-induced NF- κB transcriptional activity in NIK-deficient mice
-
Yin L., Wu L., Wesche H., Arthur C.D., White J.M., Goeddel D.V., Schreiber R.D. Defective lymphotoxin-. β receptor-induced NF- κB transcriptional activity in NIK-deficient mice Science. 291:2001;2162-2165.
-
(2001)
Science
, vol.291
, pp. 2162-2165
-
-
Yin, L.1
Wu, L.2
Wesche, H.3
Arthur, C.D.4
White, J.M.5
Goeddel, D.V.6
Schreiber, R.D.7
-
21
-
-
0035809310
-
Essential role of nuclear factor (NF)- κ B-inducing kinase and inhibitor of κ B ( IκB ) kinase α in NF- κB activation through lymphotoxin β receptor, but not through tumor necrosis factor receptor I
-
Matsushima A., Kaisho T., Rennert P.D., Nakano H., Kurosawa K., Uchida D., Takeda K., Akira S., Matsumoto M. Essential role of nuclear factor (NF)-. κ B-inducing kinase and inhibitor of κ B ( IκB ) kinase α in NF- κB activation through lymphotoxin β receptor, but not through tumor necrosis factor receptor I J. Exp. Med. 193:2001;631-636.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 631-636
-
-
Matsushima, A.1
Kaisho, T.2
Rennert, P.D.3
Nakano, H.4
Kurosawa, K.5
Uchida, D.6
Takeda, K.7
Akira, S.8
Matsumoto, M.9
-
22
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2
-
Schwandner R., Dziarski R., Wesche H., Rothe M., Kirschning C.J. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol. Chem. 274:1999;17406-17409.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17406-17409
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
Rothe, M.4
Kirschning, C.J.5
-
23
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H., Takeuchi O., Kawai T., Kaisho T., Sato S., Sanjo H., Matsumoto M., Hoshino K., Wagner H., Takeda K., Akira S. A Toll-like receptor recognizes bacterial DNA. Nature. 408:2000;740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
24
-
-
0037184115
-
Activation of macrophages by linear ( 1→3 )- β -D-Glucans. Implications for the recognition of fungi by innate immunity
-
Kataoka K., Muta T., Yamazaki S., Takeshige K. Activation of macrophages by linear (. 1→3 )- β -D-Glucans. Implications for the recognition of fungi by innate immunity J. Biol. Chem. 277:2002;36825-36831.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36825-36831
-
-
Kataoka, K.1
Muta, T.2
Yamazaki, S.3
Takeshige, K.4
-
25
-
-
0026590541
-
Dithiocarbamates as potent inhibitors of nuclear factor κ B activation in intact cells
-
Schreck R., Meier B., Männel D.N., Dröge W., Baeuerle P.A. Dithiocarbamates as potent inhibitors of nuclear factor. κ B activation in intact cells J. Exp. Med. 175:1992;1181-1194.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 1181-1194
-
-
Schreck, R.1
Meier, B.2
Männel, D.N.3
Dröge, W.4
Baeuerle, P.A.5
-
26
-
-
0030771914
-
2 in NF- κB activation by either cytokine in both primary and transformed endothelial cells
-
2 in NF- κB activation by either cytokine in both primary and transformed endothelial cells J. Biol. Chem. 272:1997;25941-25950.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25941-25950
-
-
Bowie, A.G.1
Moynagh, P.N.2
O'Neill, L.A.J.3
-
27
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase- β
-
Yin M.-J., Yamamoto Y., Gaynor R.B. The anti-inflammatory agents aspirin and salicylate inhibit the activity of. IκB kinase- β Nature. 396:1998;77-80.
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.-J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
28
-
-
0032189348
-
Proteasome inhibitors: Valuable new tools for cell biologists
-
Lee D.H., Goldberg A.L. Proteasome inhibitors: valuable new tools for cell biologists. Trends Cell Biol. 8:1998;397-403.
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 397-403
-
-
Lee, D.H.1
Goldberg, A.L.2
-
29
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T., Adachi O., Ogawa T., Takeda K., Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity. 11:1999;115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
30
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF- κB by Toll-like receptor 3
-
Alexopoulou L., Holt A.C., Medzhitov R., Flavell R.A. Recognition of double-stranded RNA and activation of NF-. κB by Toll-like receptor 3 Nature. 413:2001;732-738.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
31
-
-
0034175930
-
The IKK complex: An integrator of all signals that activate NF- κB ?
-
Israël A. The IKK complex: an integrator of all signals that activate NF-. κB ? Trends Cell Biol. 10:2000;129-133.
-
(2000)
Trends Cell Biol.
, vol.10
, pp. 129-133
-
-
Israël, A.1
-
32
-
-
0035282213
-
IκB -independent control of NF- κB activity by modulatory phosphorylations
-
Schmitz M.L., Bacher S., Kracht M. IκB -independent control of NF- κB activity by modulatory phosphorylations Trends Biochem. Sci. 26:2001;186-190.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 186-190
-
-
Schmitz, M.L.1
Bacher, S.2
Kracht, M.3
-
33
-
-
0036234459
-
Missing pieces in the NF- κB puzzle
-
Ghosh S., Karin M. Missing pieces in the NF-. κB puzzle Cell. 109:2002;S81-S96.
-
(2002)
Cell
, vol.109
-
-
Ghosh, S.1
Karin, M.2
|