-
1
-
-
0010458624
-
The isolation of cancer producing hydrocarbon from coal tar. Parts I, II, and III
-
Cook J.W., Hewett C.L., Hieger I. The isolation of cancer producing hydrocarbon from coal tar. Parts I, II, and III. J. Chem. Soc. 1933;395-405.
-
(1933)
J. Chem. Soc.
, pp. 395-405
-
-
Cook, J.W.1
Hewett, C.L.2
Hieger, I.3
-
2
-
-
0003326836
-
Trace enrichment and HPLC analysis of PAHs in edible oils and fat products, using liquid chromatography on electron acceptor stationary phases in connection with reverse phase and fluorescence detection
-
P. Garrigues, & M. Lamotte. Langhorne, PA: Gordon and Breach Science Publishers
-
Perrin J., Poirot N., Liska P., Hanras C., Theinpont A., Felix G. Trace enrichment and HPLC analysis of PAHs in edible oils and fat products, using liquid chromatography on electron acceptor stationary phases in connection with reverse phase and fluorescence detection. Garrigues P., Lamotte M. Proceedings of 13th International Symposium on Polynuclear Aromatic Hydrocarbons. 1993;Gordon and Breach Science Publishers, Langhorne, PA.
-
(1993)
Proceedings of 13th International Symposium on Polynuclear Aromatic Hydrocarbons
-
-
Perrin, J.1
Poirot, N.2
Liska, P.3
Hanras, C.4
Theinpont, A.5
Felix, G.6
-
3
-
-
0002303936
-
Relevance of polycyclic aromatic hydrocarbons as environmental carcinogens
-
P. Garrigues, & M. Lamotte. Langhorne, PA: Gordon and Breach Science Publishers
-
Grimmer G. Relevance of polycyclic aromatic hydrocarbons as environmental carcinogens. Garrigues P., Lamotte M. Proceedings of 13th International Symposium on Polynuclear Aromatic Hydrocarbons. 1993;31-41 Gordon and Breach Science Publishers, Langhorne, PA.
-
(1993)
Proceedings of 13th International Symposium on Polynuclear Aromatic Hydrocarbons
, pp. 31-41
-
-
Grimmer, G.1
-
4
-
-
0030932664
-
Determination of urinary metabolites of polycyclic aromatic hydrocarbons (PAH) for the risk assessment of PAH-exposed workers
-
Grimmer G., Jacob J., Dettbarn G., Naujack K.W. Determination of urinary metabolites of polycyclic aromatic hydrocarbons (PAH) for the risk assessment of PAH-exposed workers. Int. Arch. Occup. Environ. Health. 69:1997;231-239.
-
(1997)
Int. Arch. Occup. Environ. Health
, vol.69
, pp. 231-239
-
-
Grimmer, G.1
Jacob, J.2
Dettbarn, G.3
Naujack, K.W.4
-
5
-
-
0033565866
-
Polycyclic aromatic hydrocarbons in the diet
-
Phillips D.H. Polycyclic aromatic hydrocarbons in the diet. Mutat. Res. 443:1999;139-147.
-
(1999)
Mutat. Res.
, vol.443
, pp. 139-147
-
-
Phillips, D.H.1
-
6
-
-
0020431144
-
Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons
-
Conney A. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons. Cancer Res. 42:1982;4875-4917.
-
(1982)
Cancer Res.
, vol.42
, pp. 4875-4917
-
-
Conney, A.1
-
7
-
-
0018425446
-
Double stranded DNA stereo-selectively binds benzo[a]pyrene diol epoxides
-
Meehan T., Straub K. Double stranded DNA stereo-selectively binds benzo[a]pyrene diol epoxides. Nature. 277:1979;410-412.
-
(1979)
Nature
, vol.277
, pp. 410-412
-
-
Meehan, T.1
Straub, K.2
-
8
-
-
0024442239
-
DNA adducts from carcinogenic and non-carcinogenic enantiomers of benzo[a]pyrene dihydrodiol epoxide
-
Cheng S., Hilton B., Roman J., Dipple A. DNA adducts from carcinogenic and non-carcinogenic enantiomers of benzo[a]pyrene dihydrodiol epoxide. Chem. Res. Toxicol. 2:1989;334-340.
-
(1989)
Chem. Res. Toxicol.
, vol.2
, pp. 334-340
-
-
Cheng, S.1
Hilton, B.2
Roman, J.3
Dipple, A.4
-
10
-
-
0030911969
-
Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells
-
Hanrahan C.J., Bacolod M.D., Vyas R.R., Liu T., Geacintov N.E., Loechler E.L., Basu A.K. Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells. Chem. Res. Toxicol. 10:1997;369-377.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 369-377
-
-
Hanrahan, C.J.1
Bacolod, M.D.2
Vyas, R.R.3
Liu, T.4
Geacintov, N.E.5
Loechler, E.L.6
Basu, A.K.7
-
11
-
-
0030783590
-
2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: Configuration of the adduct bond is more important than those of the hydroxyl groups
-
2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: configuration of the adduct bond is more important than those of the hydroxyl groups. Biochemistry. 36:1997;13263-13269.
-
(1997)
Biochemistry
, vol.36
, pp. 13263-13269
-
-
Shukla, R.1
Jelinsky, S.2
Liu, T.3
Geacintov, N.E.4
Loechler, E.L.5
-
12
-
-
0030610081
-
2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G→A) in a 5′-CGT-3′ sequence context
-
2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G→A) in a 5′-CGT-3′ sequence context. Biochemistry. 36:1997;10256-10261.
-
(1997)
Biochemistry
, vol.36
, pp. 10256-10261
-
-
Shukla, R.1
Liu, T.2
Geacintov, N.E.3
Loechler, E.L.4
-
13
-
-
0032587376
-
2-dG adduct of (+)-anti-B[a]PDE induces G→A mutations in a 5′-AGA-3′ sequence context
-
2-dG adduct of (+)-anti-B[a]PDE induces G→A mutations in a 5′-AGA-3′ sequence context. Carcinogenesis. 20:1999;261-268.
-
(1999)
Carcinogenesis
, vol.20
, pp. 261-268
-
-
Shukla, R.1
Geacintov, N.E.2
Loechler, E.L.3
-
14
-
-
0027217587
-
Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis
-
Rodriguez H., Loechler E.L. Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis. Carcinogenesis. 14:1993;373-383.
-
(1993)
Carcinogenesis
, vol.14
, pp. 373-383
-
-
Rodriguez, H.1
Loechler, E.L.2
-
15
-
-
0027466342
-
Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: What controls mutagenic specificity?
-
Rodriguez H., Loechler E.L. Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: what controls mutagenic specificity? Biochemistry. 32:1993;1759-1769.
-
(1993)
Biochemistry
, vol.32
, pp. 1759-1769
-
-
Rodriguez, H.1
Loechler, E.L.2
-
16
-
-
0028812136
-
Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene
-
Rodriguez H., Loechler E.L. Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene. Mutat. Res. 326:1995;29-37.
-
(1995)
Mutat. Res.
, vol.326
, pp. 29-37
-
-
Rodriguez, H.1
Loechler, E.L.2
-
17
-
-
0027185882
-
Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene)
-
Shibutani S., Margulis L.A., Geacintov N.E., Grollman A.P. Translesional synthesis on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Biochemistry. 32:1993;7531-7541.
-
(1993)
Biochemistry
, vol.32
, pp. 7531-7541
-
-
Shibutani, S.1
Margulis, L.A.2
Geacintov, N.E.3
Grollman, A.P.4
-
18
-
-
0034730101
-
In vitro replication of primer-templates containing benzo[a]pyrene adducts by exonuclease-deficient Escherichia coli DNA polymerase I (Klenow fragment): Effect of sequence context on lesion bypass
-
Alekseyev Y.O., Romano L.J. In vitro replication of primer-templates containing benzo[a]pyrene adducts by exonuclease-deficient Escherichia coli DNA polymerase I (Klenow fragment): effect of sequence context on lesion bypass. Biochemistry. 39:2000;10431-10438.
-
(2000)
Biochemistry
, vol.39
, pp. 10431-10438
-
-
Alekseyev, Y.O.1
Romano, L.J.2
-
19
-
-
0031870798
-
Effect of single benzo[a]pyrene diol epoxide-deoxyguanosine adducts on the action of DNA polymerases in vitro
-
Lipinski L.J., Ross H.L., Zajc B., Sayer J.M., Jerina D.M., Dipple A. Effect of single benzo[a]pyrene diol epoxide-deoxyguanosine adducts on the action of DNA polymerases in vitro. Int. J. Oncol. 13:1998;269-273.
-
(1998)
Int. J. Oncol.
, vol.13
, pp. 269-273
-
-
Lipinski, L.J.1
Ross, H.L.2
Zajc, B.3
Sayer, J.M.4
Jerina, D.M.5
Dipple, A.6
-
20
-
-
0027057787
-
DNA polymerase action on benzo[a]pyrene-DNA adducts
-
Hruszkewycz A.M., Canella K.A., Peltonen K., Kotrappa L., Dipple A. DNA polymerase action on benzo[a]pyrene-DNA adducts. Carcinogenesis. 13:1992;2347-2352.
-
(1992)
Carcinogenesis
, vol.13
, pp. 2347-2352
-
-
Hruszkewycz, A.M.1
Canella, K.A.2
Peltonen, K.3
Kotrappa, L.4
Dipple, A.5
-
21
-
-
0030466095
-
Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2′-deoxyguanosine DNA adducts: Marked effects of host cell, sequence context, and chirality
-
Moriya M., Spiegel S., Fernandes A., Amin S., Liu T., Geacintov N., Grollman A.P. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2′-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality. Biochemistry. 35:1996;16646-16651.
-
(1996)
Biochemistry
, vol.35
, pp. 16646-16651
-
-
Moriya, M.1
Spiegel, S.2
Fernandes, A.3
Amin, S.4
Liu, T.5
Geacintov, N.6
Grollman, A.P.7
-
23
-
-
0033736066
-
The processing of a benzo[a]pyrene adduct into a frameshift or a base substitution mutation requires a different set of genes in Escherichia coli
-
Lenne-Samuel N., Janel-Bintz R., Kolbanovskiy A., Geacintov N., Fuchs R. The processing of a benzo[a]pyrene adduct into a frameshift or a base substitution mutation requires a different set of genes in Escherichia coli. Mol. Microbiol. 38:2000;299-307.
-
(2000)
Mol. Microbiol.
, vol.38
, pp. 299-307
-
-
Lenne-Samuel, N.1
Janel-Bintz, R.2
Kolbanovskiy, A.3
Geacintov, N.4
Fuchs, R.5
-
24
-
-
0028970884
-
2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G→A and G→C, in addition to G→T, mutations
-
2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G→A and G→C, in addition to G→T, mutations. Biochemistry. 34:1995;13545-13553.
-
(1995)
Biochemistry
, vol.34
, pp. 13545-13553
-
-
Jelinsky, S.A.1
Liu, T.2
Geacintov, N.E.3
Loechler, E.L.4
-
25
-
-
0034977788
-
Differences between the mutational consequences of replication of cis- and trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-deoxyguanosine adducts in M13mp7L2 constructs
-
Ponten I., Kroth H., Sayer J.M., Dipple A., Jerina D.M. Differences between the mutational consequences of replication of cis- and trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-deoxyguanosine adducts in M13mp7L2 constructs. Chem. Res. Toxicol. 14:2001;720-726.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 720-726
-
-
Ponten, I.1
Kroth, H.2
Sayer, J.M.3
Dipple, A.4
Jerina, D.M.5
-
26
-
-
0028027609
-
Primer extension by various polymerases using oligonucleotide templates containing stereoisomeric benzo[a]pyrene-deoxyadenosine adducts
-
Christner D.F., Lakshman M.K., Sayer J.M., Jerina D.M., Dipple A. Primer extension by various polymerases using oligonucleotide templates containing stereoisomeric benzo[a]pyrene-deoxyadenosine adducts. Biochemistry. 33:1994;14297-14305.
-
(1994)
Biochemistry
, vol.33
, pp. 14297-14305
-
-
Christner, D.F.1
Lakshman, M.K.2
Sayer, J.M.3
Jerina, D.M.4
Dipple, A.5
-
27
-
-
0032977003
-
Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo[a]pyrene 7,8-diol 9, 10-epoxide-deoxyadenosine adducts
-
Page J.E., Pilcher A.S., Yagi H., Sayer J.M., Jerina D.M., Dipple A. Mutational consequences of replication of M13mp7L2 constructs containing cis-opened benzo[a]pyrene 7,8-diol 9, 10-epoxide-deoxyadenosine adducts. Chem. Res. Toxicol. 12:1999;258-263.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 258-263
-
-
Page, J.E.1
Pilcher, A.S.2
Yagi, H.3
Sayer, J.M.4
Jerina, D.M.5
Dipple, A.6
-
28
-
-
0000933858
-
Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: Exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene
-
Buening M.K., Wislocki P.G., Levin W., Yagi H., Thakker D.R., Akagi H., et al. Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene. Proc. Natl Acad. Sci. USA. 75:1978;5358-5361.
-
(1978)
Proc. Natl Acad. Sci. USA
, vol.75
, pp. 5358-5361
-
-
Buening, M.K.1
Wislocki, P.G.2
Levin, W.3
Yagi, H.4
Thakker, D.R.5
Akagi, H.6
-
29
-
-
0018353765
-
Sites of inhibition of in vitro DNA synthesis in carcinogen- and UV-treated φ X174 DNA
-
Moore P., Strauss B.S. Sites of inhibition of in vitro DNA synthesis in carcinogen- and UV-treated φ X174 DNA. Nature. 278:1979;664-666.
-
(1979)
Nature
, vol.278
, pp. 664-666
-
-
Moore, P.1
Strauss, B.S.2
-
30
-
-
0025876653
-
Effects of benzo[a]pyrene-DNA adducts on a reconstituted replication system
-
Brown W.C., Romano L.J. Effects of benzo[a]pyrene-DNA adducts on a reconstituted replication system. Biochemistry. 30:1991;1342-1350.
-
(1991)
Biochemistry
, vol.30
, pp. 1342-1350
-
-
Brown, W.C.1
Romano, L.J.2
-
31
-
-
0037085366
-
Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts
-
Shen X., Sayer J.M., Kroth H., Ponten I., O'Donnell M., Woodgate R., et al. Efficiency and accuracy of SOS-induced DNA polymerases replicating benzo[a]pyrene-7,8-diol 9,10-epoxide A and G adducts. J. Biol. Chem. 277:2002;5265-5274.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5265-5274
-
-
Shen, X.1
Sayer, J.M.2
Kroth, H.3
Ponten, I.4
O'Donnell, M.5
Woodgate, R.6
-
32
-
-
0037023677
-
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts
-
Chiapperino D., Kroth H., Kramarczuk I.H., Sayer J.M., Masutani C., Hanaoka F., et al. Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. J. Biol. Chem. 277:2002;11765-11771.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11765-11771
-
-
Chiapperino, D.1
Kroth, H.2
Kramarczuk, I.H.3
Sayer, J.M.4
Masutani, C.5
Hanaoka, F.6
-
34
-
-
0037206593
-
Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase ζ in vitro
-
Simhadri S., Kramata P., Zajc B., Sayer J., Jerina D., Hinkle D., Wei C. Benzo[a]pyrene diol epoxide-deoxyguanosine adducts are accurately bypassed by yeast DNA polymerase ζ in vitro. Mutat. Res. 508:2002;137.
-
(2002)
Mutat. Res.
, vol.508
, pp. 137
-
-
Simhadri, S.1
Kramata, P.2
Zajc, B.3
Sayer, J.4
Jerina, D.5
Hinkle, D.6
Wei, C.7
-
35
-
-
0034327408
-
Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro
-
Zhang Y., Yuan F., Wu X., Wang M., Rechkoblit O., Taylor J.S., et al. Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro. Nucl. Acids Res. 28:2000;4138-4146.
-
(2000)
Nucl. Acids Res.
, vol.28
, pp. 4138-4146
-
-
Zhang, Y.1
Yuan, F.2
Wu, X.3
Wang, M.4
Rechkoblit, O.5
Taylor, J.S.6
-
36
-
-
0033804390
-
Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens
-
Seo K.Y., Jelinsky S.A., Loechler E.L. Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens. Mutat. Res. 463:2000;215-246.
-
(2000)
Mutat. Res.
, vol.463
, pp. 215-246
-
-
Seo, K.Y.1
Jelinsky, S.A.2
Loechler, E.L.3
-
37
-
-
0026794922
-
2-Gua, the major adduct of activated benzo[a]pyrene, when studied in an Escherichia coli plasmid using site-directed methods
-
2-Gua, the major adduct of activated benzo[a]pyrene, when studied in an Escherichia coli plasmid using site-directed methods. Carcinogenesis. 13:1992;1415-1425.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1415-1425
-
-
Mackay, W.1
Benasutti, M.2
Drouin, E.3
Loechler, E.L.4
-
38
-
-
0032560636
-
Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies
-
Page J.E., Zajc B., Oh-hara T., Lakshman M.K., Sayer J.M., Jerina D.M., Dipple A. Sequence context profoundly influences the mutagenic potency of trans-opened benzo[a]pyrene 7,8-diol 9,10-epoxide-purine nucleoside adducts in site-specific mutation studies. Biochemistry. 37:1998;9127-9137.
-
(1998)
Biochemistry
, vol.37
, pp. 9127-9137
-
-
Page, J.E.1
Zajc, B.2
Oh-hara, T.3
Lakshman, M.K.4
Sayer, J.M.5
Jerina, D.M.6
Dipple, A.7
-
39
-
-
0037006977
-
Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: Evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment)
-
Alekseyev Y.O., Romano L.J. Effects of benzo[a]pyrene adduct stereochemistry on downstream DNA replication in vitro: evidence for different adduct conformations within the active site of DNA polymerase I (Klenow fragment). Biochemistry. 41:2002;4467-4479.
-
(2002)
Biochemistry
, vol.41
, pp. 4467-4479
-
-
Alekseyev, Y.O.1
Romano, L.J.2
-
41
-
-
0031568308
-
Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 Å resolution
-
Kiefer J.R., Mao C., Hansen C.J., Basehore S.L., Hogrefe H.H., Braman J.C., Beese L.S. Crystal structure of a thermostable Bacillus DNA polymerase I large fragment at 2.1 Å resolution. Structure. 5:1997;95-108.
-
(1997)
Structure
, vol.5
, pp. 95-108
-
-
Kiefer, J.R.1
Mao, C.2
Hansen, C.J.3
Basehore, S.L.4
Hogrefe, H.H.5
Braman, J.C.6
Beese, L.S.7
-
42
-
-
0032518524
-
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal
-
Kiefer J., Mao C., Braman J., Beese L. Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature. 391:1998;304-307.
-
(1998)
Nature
, vol.391
, pp. 304-307
-
-
Kiefer, J.1
Mao, C.2
Braman, J.3
Beese, L.4
-
43
-
-
0029056926
-
Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5 Å resolution: Structural basis for thermostability
-
Korolev S., Nayal M., Barnes W.M., Di Cera E., Waksman G. Crystal structure of the large fragment of Thermus aquaticus DNA polymerase I at 2.5 Å resolution: structural basis for thermostability. Proc. Natl Acad. Sci. USA. 92:1995;9264-9268.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 9264-9268
-
-
Korolev, S.1
Nayal, M.2
Barnes, W.M.3
Di Cera, E.4
Waksman, G.5
-
44
-
-
0028983795
-
Crystal structure of Thermus aquaticus DNA polymerase
-
Kim Y., Eom S.H., Wang J., Lee D.S., Suh S.W., Steitz T.A. Crystal structure of Thermus aquaticus DNA polymerase. Nature. 376:1995;612-616.
-
(1995)
Nature
, vol.376
, pp. 612-616
-
-
Kim, Y.1
Eom, S.H.2
Wang, J.3
Lee, D.S.4
Suh, S.W.5
Steitz, T.A.6
-
45
-
-
0035369086
-
Structure of the replicating complex of a pol α family DNA polymerase
-
Franklin M.C., Wang J., Steitz T.A. Structure of the replicating complex of a pol α family DNA polymerase. Cell. 105:2001;657-667.
-
(2001)
Cell
, vol.105
, pp. 657-667
-
-
Franklin, M.C.1
Wang, J.2
Steitz, T.A.3
-
46
-
-
0031883128
-
Structural insights into DNA polymerase β fidelity: Hold it tight if you want it right
-
Beard W., Wilson S. Structural insights into DNA polymerase β fidelity: hold it tight if you want it right. Curr. Biol. 5:1998;R7-R13.
-
(1998)
Curr. Biol.
, vol.5
-
-
Beard, W.1
Wilson, S.2
-
47
-
-
0033581011
-
DNA polymerases: Structural diversity and common mechanisms
-
Steitz T. DNA polymerases: structural diversity and common mechanisms. J. Biol. Chem. 274:1999;17395-17398.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17395-17398
-
-
Steitz, T.1
-
49
-
-
0030592095
-
Structure of Taq ploymerase with DNA at the polymerase active site
-
Eom S.H., Wang J., Steitz T.A. Structure of Taq ploymerase with DNA at the polymerase active site. Nature. 382:1996;278-281.
-
(1996)
Nature
, vol.382
, pp. 278-281
-
-
Eom, S.H.1
Wang, J.2
Steitz, T.A.3
-
50
-
-
0034595517
-
Crystal structure of a pol α family DNA polymerase from the hyperthermiphilic archaeon Thermococcus sp 9°N-7
-
Rodriguez A., Park H.-W., Mao C., Beese L. Crystal structure of a pol α family DNA polymerase from the hyperthermiphilic archaeon Thermococcus sp 9°N-7. J. Mol. Biol. 299:2000;447-462.
-
(2000)
J. Mol. Biol.
, vol.299
, pp. 447-462
-
-
Rodriguez, A.1
Park, H.-W.2
Mao, C.3
Beese, L.4
-
51
-
-
0035997351
-
Active site tightness and substrate fit in DNA replication
-
Kool E.T. Active site tightness and substrate fit in DNA replication. Annu. Rev. Biochem. 71:2002;191-219.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 191-219
-
-
Kool, E.T.1
-
53
-
-
0025783442
-
Fidelity mechanisms in DNA replication
-
Echols H., Goodman M. Fidelity mechanisms in DNA replication. Annu. Rev. Biochem. 60:1991;477-511.
-
(1991)
Annu. Rev. Biochem.
, vol.60
, pp. 477-511
-
-
Echols, H.1
Goodman, M.2
-
54
-
-
0030924437
-
Hydrogen bonding revisited: Geometric selection as a principal determinant of DNA replication fidelity
-
Goodman M.F. Hydrogen bonding revisited: geometric selection as a principal determinant of DNA replication fidelity. Proc. Natl Acad. Sci. USA. 94:1997;10493-10495.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 10493-10495
-
-
Goodman, M.F.1
-
56
-
-
0032535528
-
Crystal structure of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: Structural basis for nucleotide incorporation
-
Li Y., Korolev S., Waksman G. Crystal structure of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation. EMBO J. 17:1998;7514-7525.
-
(1998)
EMBO J.
, vol.17
, pp. 7514-7525
-
-
Li, Y.1
Korolev, S.2
Waksman, G.3
-
57
-
-
0027220197
-
Conformational coupling in DNA polymerase fidelity
-
Johnson K. Conformational coupling in DNA polymerase fidelity. Annu. Rev. Biochem. 62:1993;685-713.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 685-713
-
-
Johnson, K.1
-
58
-
-
0026026192
-
An induced-fit kinetic mechanism for DNA replication fidelity: Direct measurement by single-turnover kinetics
-
Wong I., Patel S.S., Johnson K.A. An induced-fit kinetic mechanism for DNA replication fidelity: direct measurement by single-turnover kinetics. Biochemistry. 30:1991;526-537.
-
(1991)
Biochemistry
, vol.30
, pp. 526-537
-
-
Wong, I.1
Patel, S.S.2
Johnson, K.A.3
-
59
-
-
0031774216
-
Replication of non-hydrogen bonded bases by DNA polymerases: A mechanism for steric matching
-
Kool E.T. Replication of non-hydrogen bonded bases by DNA polymerases: a mechanism for steric matching. Biopolymers. 48:1998;3-17.
-
(1998)
Biopolymers
, vol.48
, pp. 3-17
-
-
Kool, E.T.1
-
60
-
-
0034678016
-
Mimicking the structure and function of DNA: Insights into DNA stability and replication
-
Kool E.T., Morales J.C., Guckian K.M. Mimicking the structure and function of DNA: insights into DNA stability and replication. Angew. Chem., Int. Ed. Engl. 39:2000;990-1009.
-
(2000)
Angew. Chem., Int. Ed. Engl.
, vol.39
, pp. 990-1009
-
-
Kool, E.T.1
Morales, J.C.2
Guckian, K.M.3
-
61
-
-
0030930760
-
Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
-
Sawaya M., Prasad R., Wilson S., Kraut J., Pelletier H. Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: evidence for an induced fit mechanism. Biochemistry. 36:1997;11205-11215.
-
(1997)
Biochemistry
, vol.36
, pp. 11205-11215
-
-
Sawaya, M.1
Prasad, R.2
Wilson, S.3
Kraut, J.4
Pelletier, H.5
-
62
-
-
0029817866
-
Crystal structures of human DNA polymerase β complexed with DNA: Implications for catalytic mechanism, processivity, and fidelity
-
Pelletier H., Sawaya M.R., Wolfle W., Wilson S.H., Kraut J. Crystal structures of human DNA polymerase β complexed with DNA: implications for catalytic mechanism, processivity, and fidelity. Biochemistry. 35:1996;12742-12761.
-
(1996)
Biochemistry
, vol.35
, pp. 12742-12761
-
-
Pelletier, H.1
Sawaya, M.R.2
Wolfle, W.3
Wilson, S.H.4
Kraut, J.5
-
63
-
-
0032518398
-
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
-
Doublie S., Tabor S., Long A., Richardson C., Ellenberger T. Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution. Nature. 391:1998;251-258.
-
(1998)
Nature
, vol.391
, pp. 251-258
-
-
Doublie, S.1
Tabor, S.2
Long, A.3
Richardson, C.4
Ellenberger, T.5
-
64
-
-
0034711010
-
Functional hydrogen-bonding map of the minor groove binding tracks of six DNA polymerases
-
Morales J.C., Kool E.T. Functional hydrogen-bonding map of the minor groove binding tracks of six DNA polymerases. Biochemistry. 39:2000;12979-12988.
-
(2000)
Biochemistry
, vol.39
, pp. 12979-12988
-
-
Morales, J.C.1
Kool, E.T.2
-
65
-
-
0033577360
-
Minor groove interactions between polymerase and DNA: More essential to replication than Watson-Crick hydrogen bonds
-
Morales J., Kool E. Minor groove interactions between polymerase and DNA: More essential to replication than Watson-Crick hydrogen bonds. J. Am. Chem. Soc. 121:1999;2323-2324.
-
(1999)
J. Am. Chem. Soc.
, vol.121
, pp. 2323-2324
-
-
Morales, J.1
Kool, E.2
-
66
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang H., Chopra R., Verdine G., Harrison S. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science. 282:1998;1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Verdine, G.3
Harrison, S.4
-
67
-
-
0028033532
-
Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase
-
Zinnen S., Hsieh J.C., Modrich P. Misincorporation and mispaired primer extension by human immunodeficiency virus reverse transcriptase. J. Biol. Chem. 269:1994;24195-24202.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24195-24202
-
-
Zinnen, S.1
Hsieh, J.C.2
Modrich, P.3
-
68
-
-
0028075950
-
Proofreading DNA recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I
-
Carver T.E. Jr, Hochstrasser R.A., Millar D.P. Proofreading DNA recognition of aberrant DNA termini by the Klenow fragment of DNA polymerase I. Proc. Natl Acad. Sci. USA. 91:1994;10670-10674.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 10670-10674
-
-
Carver T.E., Jr.1
Hochstrasser, R.A.2
Millar, D.P.3
-
69
-
-
0036382913
-
Toward understanding the mutagenicity of an environmental carcinogen: Structural insights into nucleotide incorporation preferences
-
Perlow R.A., Broyde S. Toward understanding the mutagenicity of an environmental carcinogen: structural insights into nucleotide incorporation preferences. J. Mol. Biol. 322:2002;291-309.
-
(2002)
J. Mol. Biol.
, vol.322
, pp. 291-309
-
-
Perlow, R.A.1
Broyde, S.2
-
70
-
-
0035366319
-
Evading the proofreading machinery of a replicative DNA polymerase: Induction of a mutation by an environmental carcinogen
-
Perlow R.A., Broyde S. Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen. J. Mol. Biol. 309:2001;519-536.
-
(2001)
J. Mol. Biol.
, vol.309
, pp. 519-536
-
-
Perlow, R.A.1
Broyde, S.2
-
71
-
-
0026033193
-
Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant
-
Patel S.S., Wong I., Johnson K.A. Pre-steady-state kinetic analysis of processive DNA replication including complete characterization of an exonuclease-deficient mutant. Biochemistry. 30:1991;511-525.
-
(1991)
Biochemistry
, vol.30
, pp. 511-525
-
-
Patel, S.S.1
Wong, I.2
Johnson, K.A.3
-
72
-
-
0032086491
-
Coordinated leading and lagging strand DNA synthesis on a minicircular template
-
Lee J., Chastain P.D., Kusakabe T., Griffith J.D., Richardson C.C. Coordinated leading and lagging strand DNA synthesis on a minicircular template. Mol. Cell. 1:1998;1001-1010.
-
(1998)
Mol. Cell.
, vol.1
, pp. 1001-1010
-
-
Lee, J.1
Chastain, P.D.2
Kusakabe, T.3
Griffith, J.D.4
Richardson, C.C.5
-
75
-
-
0031820604
-
Effects of bulky polycyclic aromatic hydrocarbon adducts on DNA replication by exonuclease deficient T7 and T4 DNA polymerases
-
Keohavong P., Shukla R., Melacrinos A., Day B., Reha-Krantz L. Effects of bulky polycyclic aromatic hydrocarbon adducts on DNA replication by exonuclease deficient T7 and T4 DNA polymerases. DNA Cell Biol. 17:1998;541-549.
-
(1998)
DNA Cell Biol.
, vol.17
, pp. 541-549
-
-
Keohavong, P.1
Shukla, R.2
Melacrinos, A.3
Day, B.4
Reha-Krantz, L.5
-
76
-
-
0035916294
-
Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: Evidence for inhibition of the catalytically active ternary complex formation
-
Alekseyev Y., Dzantiev L., Romano L. Effects of benzo[a]pyrene DNA adducts on Escherichia coli DNA polymerase I (Klenow fragment) primer-template interactions: evidence for inhibition of the catalytically active ternary complex formation. Biochemistry. 40:2001;2282-2290.
-
(2001)
Biochemistry
, vol.40
, pp. 2282-2290
-
-
Alekseyev, Y.1
Dzantiev, L.2
Romano, L.3
-
77
-
-
0032518374
-
A mechanism for all polymerases
-
Steitz T.A. A mechanism for all polymerases. Nature. 391:1998;231-232.
-
(1998)
Nature
, vol.391
, pp. 231-232
-
-
Steitz, T.A.1
-
79
-
-
0022537369
-
Mechanism of DNA polymerase I: Exonuclease/polymerase activity switch and DNA sequence dependence of pyrophosphorolysis and misincorporation reactions
-
Mizrahi V., Benkovic P., Benkovic S.J. Mechanism of DNA polymerase I: exonuclease/polymerase activity switch and DNA sequence dependence of pyrophosphorolysis and misincorporation reactions. Proc. Natl Acad. Sci. USA. 83:1986;5769-5773.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 5769-5773
-
-
Mizrahi, V.1
Benkovic, P.2
Benkovic, S.J.3
-
80
-
-
0026785756
-
Minimal kinetic mechanism for misincorporation by DNA polymerase I (Klenow fragment)
-
Eger B.T., Benkovic S.J. Minimal kinetic mechanism for misincorporation by DNA polymerase I (Klenow fragment). Biochemistry. 31:1992;9227-9236.
-
(1992)
Biochemistry
, vol.31
, pp. 9227-9236
-
-
Eger, B.T.1
Benkovic, S.J.2
-
81
-
-
0028892284
-
Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction
-
Cosman M., Hingerty B.E., Geacintov N.E., Broyde S., Patel D.J. Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction. Biochemistry. 34:1995;15334-15350.
-
(1995)
Biochemistry
, vol.34
, pp. 15334-15350
-
-
Cosman, M.1
Hingerty, B.E.2
Geacintov, N.E.3
Broyde, S.4
Patel, D.J.5
-
82
-
-
0030721639
-
Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction
-
Feng B., Gorin A., Hingerty B.E., Geacintov N.E., Broyde S., Patel D.J. Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction. Biochemistry. 36:1997;13769-13779.
-
(1997)
Biochemistry
, vol.36
, pp. 13769-13779
-
-
Feng, B.1
Gorin, A.2
Hingerty, B.E.3
Geacintov, N.E.4
Broyde, S.5
Patel, D.J.6
-
83
-
-
0026527186
-
Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA
-
Cosman M., de los Santos C., Fiala R., Hingerty B.E., Singh S.B., Ibanez V., et al. Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA. Proc. Natl Acad. Sci. USA. 89:1992;1914-1918.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1914-1918
-
-
Cosman, M.1
De los Santos, C.2
Fiala, R.3
Hingerty, B.E.4
Singh, S.B.5
Ibanez, V.6
-
84
-
-
0033533495
-
Primer length dependence of binding of DNA polymerase I Klenow fragment to template-primer complexes containing site-specific bulky lesions
-
Rechkoblit O., Amin S., Geacintov N.E. Primer length dependence of binding of DNA polymerase I Klenow fragment to template-primer complexes containing site-specific bulky lesions. Biochemistry. 38:1999;11834-11843.
-
(1999)
Biochemistry
, vol.38
, pp. 11834-11843
-
-
Rechkoblit, O.1
Amin, S.2
Geacintov, N.E.3
-
85
-
-
0034556629
-
Error-prone lesion bypass by human DNA polymerase η
-
Zhang Y., Yuan F., Wu X., Rechkoblit O., Taylor J.S., Geacintov N.E., Wang Z. Error-prone lesion bypass by human DNA polymerase η Nucl. Acids Res. 28:2000;4717-4724.
-
(2000)
Nucl. Acids Res.
, vol.28
, pp. 4717-4724
-
-
Zhang, Y.1
Yuan, F.2
Wu, X.3
Rechkoblit, O.4
Taylor, J.S.5
Geacintov, N.E.6
Wang, Z.7
-
87
-
-
0035997344
-
Error-prone repair DNA polymerases in prokaryotes and eukaryotes
-
Goodman M.F. Error-prone repair DNA polymerases in prokaryotes and eukaryotes. Annu. Rev. Biochem. 71:2002;17-50.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 17-50
-
-
Goodman, M.F.1
-
88
-
-
0035812849
-
Crystal structure of a Y-family DNA polymerase in action: A mechanism for error-prone and lesion-bypass replication
-
Ling H., Boudsocq F., Woodgate R., Yang W. Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication. Cell. 107:2001;91-102.
-
(2001)
Cell
, vol.107
, pp. 91-102
-
-
Ling, H.1
Boudsocq, F.2
Woodgate, R.3
Yang, W.4
-
89
-
-
0029633186
-
AMBER, a package of computer programs applying molecular mechanics, normal mode analysis, molecular dynamics, and free energy calculations to simulate the structural and energetic properties of molecules
-
Pearlman D.A., Case D.A., Caldwell J.W., Ross W.S., Cheatham T.E.I., DeBolt S., et al. AMBER, a package of computer programs applying molecular mechanics, normal mode analysis, molecular dynamics, and free energy calculations to simulate the structural and energetic properties of molecules. Comp. Phys. Commun. 91:1995;1-41.
-
(1995)
Comp. Phys. Commun.
, vol.91
, pp. 1-41
-
-
Pearlman, D.A.1
Case, D.A.2
Caldwell, J.W.3
Ross, W.S.4
Cheatham, T.E.I.5
DeBolt, S.6
-
90
-
-
0029011701
-
A second generation force field for the simulation of proteins, nucleic acids, and organic molecules
-
Cornell W.D., Cieplak P., Bayly C.I., Gould I.R., Merz K., Ferguson D., et al. A second generation force field for the simulation of proteins, nucleic acids, and organic molecules. J. Am. Chem. Soc. 117:1995;5179-5197.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 5179-5197
-
-
Cornell, W.D.1
Cieplak, P.2
Bayly, C.I.3
Gould, I.R.4
Merz, K.5
Ferguson, D.6
-
91
-
-
0032922174
-
A modified version of the Cornell force field with improved sugar pucker phases and helical repeat
-
Cheatham T., Cieplak P., Kollman P., et al. A modified version of the Cornell force field with improved sugar pucker phases and helical repeat. J. Biomol. Struct. Dynam. 16:1999;845-862.
-
(1999)
J. Biomol. Struct. Dynam.
, vol.16
, pp. 845-862
-
-
Cheatham, T.1
Cieplak, P.2
Kollman, P.3
-
92
-
-
0031788539
-
Molecular dynamics and continuum solvent studies of the stability of polyG-polyC and polyA-polyT DNA duplexes in solution
-
Cheatham T.E. III, Srinivasan J., Case D.A., Kollman P.A. Molecular dynamics and continuum solvent studies of the stability of polyG-polyC and polyA-polyT DNA duplexes in solution. J. Biomol. Struct. Dynam. 16:1998;265-280.
-
(1998)
J. Biomol. Struct. Dynam.
, vol.16
, pp. 265-280
-
-
Cheatham T.E. III1
Srinivasan, J.2
Case, D.A.3
Kollman, P.A.4
-
95
-
-
33846823909
-
Particle Mesh Ewald - An N log(N) method for Ewald sums in large systems
-
Darden T.A., York D., Pedersen L. Particle Mesh Ewald - an N log(N) method for Ewald sums in large systems. J. Chem. Phys. 98:1993;10089-10092.
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10092
-
-
Darden, T.A.1
York, D.2
Pedersen, L.3
-
96
-
-
0033954256
-
The Protein Data Bank
-
Berman H.M., Westbrook J., Feng Z., Gilliland G., Bhat T.N., Weissig H., et al. The Protein Data Bank. Nucl. Acids Res. 28:2000;235-242.
-
(2000)
Nucl. Acids Res.
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
-
97
-
-
84990406847
-
Dielectric effects in biopolymers: The theory of ionic saturation revisited
-
Hingerty B., Ritchie R., Ferrell T., Turner J. Dielectric effects in biopolymers: the theory of ionic saturation revisited. Biopolymers. 24:1985;427-439.
-
(1985)
Biopolymers
, vol.24
, pp. 427-439
-
-
Hingerty, B.1
Ritchie, R.2
Ferrell, T.3
Turner, J.4
-
98
-
-
0001006487
-
Simulaid: A collection of utilities designed to help setting up molecular dynamics simulations
-
Mezei M. Simulaid: a collection of utilities designed to help setting up molecular dynamics simulations. J. Comp. Chem. 18:1997;812-815.
-
(1997)
J. Comp. Chem.
, vol.18
, pp. 812-815
-
-
Mezei, M.1
-
99
-
-
0021107965
-
Solvent-accessible surfaces of proteins and nucleic acids
-
Connolly M.L. Solvent-accessible surfaces of proteins and nucleic acids. Science. 221:1983;709-713.
-
(1983)
Science
, vol.221
, pp. 709-713
-
-
Connolly, M.L.1
-
100
-
-
0029027343
-
Complete and tissue-independent methylation of CpG sites in the p53 gene: Implications for mutations in human cancers
-
Tornaletti S., Pfeifer G.P. Complete and tissue-independent methylation of CpG sites in the p53 gene: implications for mutations in human cancers. Oncogene. 10:1995;1493-1499.
-
(1995)
Oncogene
, vol.10
, pp. 1493-1499
-
-
Tornaletti, S.1
Pfeifer, G.P.2
|