The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G → a) in a 5'-CGT-3' sequence context

Biochemistry

Volumn 36, Issue 33, 1997, Pages 10256-10261

  Shukla, Rajiv ^a   Liu, Tongming ^b   Geacintov, Nicholas E ^b   Loechler, Edward L ^a  

^a Boston University   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; BENZO[A]PYRENE; NUCLEIC ACID BASE; BENZO(A)PYRENE 7,8 DIHYDRODIOL 9,10 EPOXIDE DNA; BENZO(A)PYRENE-7,8-DIHYDRODIOL-9,10-EPOXIDE-DNA; BENZO[A]PYRENE 7,8 DIHYDRODIOL 9,10 OXIDE; MUTAGENIC AGENT; SUPF TRNA; TRANSFER RNA;

ARTICLE; DNA ADDUCT; DNA CONFORMATION; DNA SEQUENCE; FRAMESHIFT MUTATION; GENE DELETION; GENE INSERTION; GENE MUTATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PLASMID; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SOS CHROMOTEST; CHEMISTRY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MUTAGENESIS; MUTATION; SUPPRESSOR GENE;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA ADDUCTS; GENES, SUPPRESSOR; MUTAGENESIS; MUTAGENS; MUTATION; PLASMIDS; RNA, TRANSFER;

EID: 0030610081     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970541+     Document Type: Article

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