How stereochemistry affects mutagenesis by N2-deoxyguanosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene: Configuration of the adduct bond is more important than those of the hydroxyl groups

Biochemistry

Volumn 36, Issue 43, 1997, Pages 13263-13269

  Shukla, Rajiv ^a   Jelinsky, Scott ^a   Liu, Tongming ^b   Geacintov, Nicholas E ^b   Loechler, Edward L ^a  

^a Boston University   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; 7,8,9,10 TETRAHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE 9,10 OXIDE; DEOXYGUANOSINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CHEMICAL MUTAGENESIS; DNA ADDUCT; GENE MUTATION; HYPOTHESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; STEREOCHEMISTRY; STRUCTURE ANALYSIS;

BASE SEQUENCE; BENZOPYRENES; DNA ADDUCTS; HYDROXYL RADICAL; MOLECULAR CONFORMATION; MUTAGENESIS; OLIGONUCLEOTIDES; PLASMIDS; STEREOISOMERISM;

EID: 0030783590     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971195z     Document Type: Article

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