Coordinated leading and lagging strand DNA synthesis on a minicircular template

Molecular Cell

Volumn 1, Issue 7, 1998, Pages 1001-1010

  Lee, Joonsoo ^a   Chastain II, Paul D ^b   Kusakabe, Takahiro ^a,c   Griffith, Jack D ^b   Richardson, Charles C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIRCULAR DNA; DNA; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE GAMMA; DNA PRIMASE; HELICASE; OKAZAKI FRAGMENTS; SINGLE STRANDED DNA; VIRUS DNA;

ARTICLE; BACTERIOPHAGE T7; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; CONFORMATION; DNA REPLICATION; DNA TEMPLATE; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ULTRASTRUCTURE;

BACTERIOPHAGE T7; BASE SEQUENCE; BINDING SITES; DNA; DNA HELICASES; DNA POLYMERASE III; DNA PRIMASE; DNA REPLICATION; DNA, CIRCULAR; DNA, SINGLE-STRANDED; DNA, VIRAL; DNA-BINDING PROTEINS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; TEMPLATES, GENETIC;

EID: 0032086491     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80100-8     Document Type: Article

References (39)

1. Alberts, B.M., Barry, J., Bedinger, P., Formosa, T., Jongeneel, C.V., and Kreuzer, K.N. (1983). Studies on DNA replication in the bacteriophage T4 in vitro system. Cold Spring Harbor Symp. Quant. Biol. 47, 655-668.
2. Alberts, B.M., Morris, C., Mace, D., Sinha, N., Bittner, M., and Moran, L. (1975). Reconstruction of the T4 bacteriophage DNA replication apparatus from purified components. In DNA Synthesis and Its Regulation, M. Goulian, P. Hanawalt, and C.F. Fox, eds. (Menlo Park, CA: W.A. Benjamin), pp. 241-269.
3. Arai, N., and Kornberg, A. (1981). Rep protein as a helicase in an active, isolatable replication fork of duplex φX 174 DNA. J. Biol. Chem. 256, 5294-5298.
4. Bernstein, J.A., and Richardson, C.C. (1988). A 7kd region of the bacteriophage T7 gene 4 protein is required for primase but not for helicase activity. Proc. Natl. Acad. Sci. USA 85, 396-400.
5. Chase, J.W., and Williams, K.R. (1986). Single-stranded DNA binding proteins required for DNA replication. Annu. Rev. Biochem. 55, 103-136.
6. Debyser, Z., Tabor, S., and Richardson, C.C. (1994). Coordination of leading and lagging strand DNA synthesis at the replication fork of bacteriophage T7. Cell 77, 157-166.
7. Doublié, S., Tabor, S., Long, A., Richardson, C.C., and Ellenberger, T. (1998). Crystal structure of bacteriophage T7 DNA polymerase complex at 2.2 Å resolution. Nature 391, 251-258.
8. Egelman, E.H., Yu, X., Wild, R., Hingorani, M.M., and Patel, S.S. (1995). Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases. Proc. Natl. Acad. Sci. USA 92, 3869-3873.
9. Fire, A., and Xu, S.-Q. (1995). Rolling replication of short DNA circles. Proc. Natl. Acad. Sci. USA 92, 4641-4645.
10. Griffith, J., and Christiansen, G. (1978). Electron microscope visualization of chromatin and other DNA-protein complexes. Annu. Rev. Biophys. Bioeng. 7, 19-35.
11. 1-ATPase. Proc. Natl. Acad. Sci. USA 94, 5012-5017.
12. Huber, H.E., Tabor, S., and Richardson, C.C. (1987). Escherichia coli thioredoxin stabilizes complexes of bacteriophage T7 DNA polymerase and primed templates. J. Biol. Chem. 262, 16212-16223.
13. Kim, S., Dallmann, H.G., McHenry, C.S., and Marian, K.J. (1996). τ couples the leading-and lagging-strand polymerases at the Escherichia coli DNA replication fork. J. Biol. Chem. 271, 21406-21412.
14. Kim, Y.T., Tabor, S., Bortner, C., Griffith, J.D., and Richardson, C.C. (1992a). Purification and characterization of the bacteriophage T7 gene 2.5 protein. J. Biol. Chem. 267, 15022-15031.
15. Kim, Y.T., Tabor, S., Churchich, J.E., and Richardson, C.C. (1992b). Interactions of the gene 2.5 protein and DNA polymerase of bacteriophage T7. J. Biol. Chem. 267, 15032-15040.
16. Kim, Y.T., and Richardson, C.C. (1993). Bacteriophage T7 gene 2.5 protein: an essential protein for DNA replication. Proc. Natl. Acad. Sci. USA 90, 10173-10177.
17. Kim, Y.T., and Richardson, C.C. (1994). Acidic carboxyl-terminal domain of gene 2.5 protein of bacteriophage T7 is essential for protein-protein interactions. J. Biol. Chem. 269, 5270-5278.
18. Lechner, R.L., and Richardson, C.C. (1983). A preformed, topologically stable replication fork: characterization of leading strand DNA synthesis catalyzed by T7 DNA polymerase and gene 4 protein. J. Biol. Chem. 258, 11185-11196.
19. Lohman, T.M., and Ferrari, M.E. (1994). Escherichia coli single-stranded DNA-binding protein: multiple DNA-binding modes and cooperativities. Annu. Rev. Biochem. 63, 527-570.
20. Maki, H., Maki, S., and Kornberg, A. (1988). DNA polymerase III holoenzyme of Escherichia coli. IV. The holoenzyme is an asymmetric dimer with twin active sites. J. Biol. Chem. 263, 6570-6578.
21. Matson, S.W., and Richardson, C.C. (1983). DNAdependent nucleoside 5′-triphosphatase activity of the gene 4 protein of bacteriophage T7. J. Biol. Chem. 258, 14009-14016.
22. Matson, S.W., Tabor, S., and Richardson, C.C. (1983). The gene 4 protein of bacteriophage T7: characterization of helicase activity. J. Biol. Chem. 258, 14017-14024.
23. McHenry, C.S. (1991). DNA polymerase III holoenzyme, components, structure, and mechanism of a true replication complex. J. Biol. Chem. 266, 19127-19130.
24. Mendelman, L.V., and Richardson, C.C. (1991). Requirements for primer synthesis by bacteriophage T7 63-kDa gene 4 protein: roles of template sequence and T7 56-kDa gene 4 protein. J. Biol. Chem. 266, 23240-23250.
25. Nakai, H., and Richardson, C.C. (1986). Interactions of the DNA polymerase and gene 4 protein of bacteriophage T7: protein-protein and protein-DNA interactions involved in RNA-primed DNA synthesis. J. Biol. Chem. 261, 15208-15216.
26. Nakai, H., and Richardson, C.C. (1988). Leading and lagging strand synthesis at the replication fork of bacteriophage T7: distinct properties of T7 gene 4 protein as a helicase and primase. J. Biol. Chem. 263, 9818-9830.
27. Notarnicola, S.M., Park, K., Griffith, J.D., and Richardson, C.C. (1995). A domain of the gene 4 helicase/primase of bacteriophage T7 required for the formation of an active hexamer. J. Biol. Chem. 270, 20215-20224.
28. Notarnicola, S.M., Mulcahy, H.L., Lee, J., and Richardson, C.C. (1997). The acidic carboxyl terminus of the bacteriophage T7 gene 4 helicase/primase interacts with T7 DNA polymerase. J. Biol. Chem. 272, 18425-18433.
29. Onrust, R., Finkelstein, J., Turner, J., Naktinis, V., and O'Donnell, M. (1995). Assembly of a chromosomal replication machine: two polymerases, a clamp loader, and sliding clamps in a one holoenzyme particle. J. Biol. Chem. 270, 13366-13377.
30. Park, K., Debyser, Z., Tabor, S., Richardson, C.C., and Griffith, J.D. (1998). Formation of a DNA loop at the replication fork generated by bacteriophage T7 replication proteins. J. Biol. Chem. 273, in press.
31. Richardson, C.C. (1983). Bacteriophage T7: minimal requirements for the replication of a duplex DNA molecule. Cell 33, 315-317.
32. Romano, L.J., and Richardson, C.C. (1979). Characterization of the ribonucleic acid primers and the deoxyribonucleic acid product synthesized by the DNA polymerase and gene 4 protein of bacteriophage T7. J. Biol. Chem. 254, 10483-10489.
33. Scherzinger, E., Lanka, E.F., and Hillenbrand, G. (1979). Role of bacteriophage T7 DNA primase in the initiation of DNA strand synthesis. Nucleic Acids Res. 4, 4151-4163.
34. Tabor, S., and Richardson, C.C. (1981). Template recognition sequence for RNA primer synthesis by the gene 4 protein of bacteriophage T7. Proc. Natl. Acad. Sci. USA 78, 205-209.
35. Tabor, S., and Richardson, C.C. (1987). Escherichia coli thioredoxin confers processivity on the DNA polymerase activity of the gene 5 protein of bacteriophage T7. J. Biol. Chem. 262, 16224-16232.
36. Tabor, S., and Richardson, C.C. (1995). A single residue in DNA polymerase of the Escherichia coli DN A polymerase I family is critical for distinguishing between deoxy-and dideoxynucleotides. Proc. Natl. Acad. Sci. USA 92, 6339-6343.
37. Tougu, K., and Marians, J.K. (1996). The interaction between helicase and primase sets the replication fork clock. J. Biol. Chem. 271, 21398-21405.
38. Yuzhakov, A., Turner, J., and O'Donnell, M. (1996). Replisome assembly reveals the basis for asymmetric function in leading and lagging strand replication. Cell 86, 877-886.
39. Wu, C.A., Zechner, E.L., Hughes, A.J., Franden, M.A., McHenry, C.S., and Marians, K.J. (1994). Coordinated leading and lagging strand synthesis at the E. coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme. J. Biol. Chem. 267, 4064-4073.