The processing of a Benzo(a)pyrene adduct into a frameshift or a base substitution mutation requires a different set of genes in Escherichia coli

Molecular Microbiology

Volumn 38, Issue 2, 2000, Pages 299-307

  Lenne Samuel, Nathalie ^a   Janel Bintz, Regine ^a   Kolbanovskiy, Aleksandr ^b   Geacintov, Nicholas E ^b   Fuchs, Robert P P ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; DIHYDROXYBENZO[A]PYRENE OXIDE; DNA POLYMERASE; GUANINE DERIVATIVE; HOLOENZYME;

ARTICLE; BACTERIAL GENE; ESCHERICHIA COLI; FRAMESHIFT MUTATION; GENE CONTROL; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

BACTERIAL PROTEINS; BASE PAIRING; BENZO(A)PYRENE; CARCINOGENS, ENVIRONMENTAL; DNA ADDUCTS; DNA REPLICATION; DNA, BACTERIAL; DNA-DIRECTED DNA POLYMERASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FRAMESHIFT MUTATION; GENES, BACTERIAL; MUTAGENESIS, SITE-DIRECTED; MUTAGENS; SOS RESPONSE (GENETICS);

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA; PROKARYOTA;

EID: 0033736066     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.02116.x     Document Type: Article

References (30)

1. Lesions in DNA: Hurdles for polymerases
2. SOS mutagenesis results from up-regulation of translesion synthesis
3. N-2-aminofluorene and N-2-acetylaminofluorene adducts: The local sequence context of an adduct and its chemical structure determine its replication properties
4. Binding and mutation spectra of the carcinogen N-2-aminofluorene. A correlation between the conformation of the premutagenic lesion and the mutation specificity
5. Sequence-dependent modulation of frameshift mutagenesis at Narl-derived mutation hot spots
6. Mismatch amplification mutation assay (MAMA): Application to the c-H-ras gene
7. DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo(a)pyrene dihydrodiol epoxide
8. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons
9. Replication of damaged DNA: Molecular defect in Xeroderma pigmentosum variant cells
10. NMR solution structures of stereoisomeric covalent polycyclic aromatic carcinogen-DNA adducts: Principles, patterns, and diversity
11. Analysis of cytokine mRNA and DNA: Detection and quantitation by competitive polymerase chain reaction
12. Sequence specific mutagenesis of the major (+)-anti-benzo(a)pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in E. coli cells
13. SOS and Mayday: Multiple inducible mutagenic pathways in E. coli
14. The major, N2-Gua adduct of the (+)-antibenzo(a)pyrene diol epoxide is capable of inducing G→A and G→C, in addition to G→T, mutations
15. Cellular strategies for accommodating replication-hindering adducts in DNA: Control by the SOS response in E. coli
16. Alkylation of polyguanylic acid at the 2-amino group and phosphate by the potent mutagen (+/-)-7beta,8alpha-dihydroxy-9beta, 10beta-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene
17. Molecular modeling of the major adduct of (+)-anti-B[a]PDE (N2-dG) in the eight conformations and the five DNA sequences most relevant to base substitution mutagenesis
18. A hypothesis for what conformation of the major adduct of (+)-anti-B[a]PDE(N2-dG) causes G → T versus G → A mutations based upon a correlation between mutagenesis and molecular modeling results
19. Carcinogen-induced frameshift mutagenesis in repetitive sequences
20. Mutagenesis by (+)-anti-B(a)P-N2-Gua, the major adduct of activated benzo(a)pyrene, when studied in an E. coli plasmid using site directed methods
21. Synthesis and characterization of covalent adducts derived from the binding of benzo[a]pyrene diol expoxide to a -GGG- sequence in a deoxyoligonucleotide
22. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: Marked effects of host cell, sequence context, and chirality
23. SOS factors involved in translesion synthesis
24. Mutational specificity of the (+)-anti-diol epoxide of B(a)P in a supF gene of an E. coli plasmid: DNA sequence context effects influences hot spots, mutagenic specificity and the extent of SOS enhancement of mutagenesis
25. Isolation and characterization of oligodeoxynucleotides containing dG-N2-AAF and oxidation products of dG-C8-AAF
26. Translesional synthesis on DNA template containing a single stereoisomer of dG(+)- or dG(-)-anti-BPDE (7,8-dihydro-anti-9, 10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrenene)
27. The major, N2-dG adduct of (+)-anti-B(a)PDE shows a dramatic different mutagenic specificity (predominantly G → A) in a 5'-CGT-3' sequence context
28. The major N2-dG adduct of (+)-anti-B(a)PDE induces G → A mutations in a 5'-AGA-3' sequence context
29. Leading versus lagging strand mutagenesis induced by 7,8-dihydro-8-oxo-2'-deoxyguanosine in E. coli
30. Benzo[a]pyrene diol epoxides as intermediates in nucleic acid binding in vitro and in vivo