In vivo and in vitro activation of caspase-8 and -3 associated with Helicobacter pylori infection

Microbes and Infection

Volumn 4, Issue 7, 2002, Pages 713-722

  Ashktorab, Hassan ^a,b   Neapolitano, Mattew ^b   Bomma, Chandara ^b   Allen, Cornel ^a,b   Ahmed, Amel ^a,b   Dubois, Andre ^c   Naab, Tammy ^b   Smoot, Duane T ^a,b  

^a HOWARD UNIVERSITY CANCER CENTER   (United States)

^b HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

AGS cells; Apoptosis; Caspase 3; Caspase 8; DFF45; Helicobacter pylori; Immunohistochemistry; PARP; Rhesus monkeys

Indexed keywords

BACTERIAL PROTEIN; CASPASE 3; CASPASE 8; DNA FRAGMENTATION FACTOR 45; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; CARCINOMA CELL; CELL STIMULATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME DEGRADATION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; MONKEY; NONHUMAN; PRIORITY JOURNAL; STAINING; STOMACH ADENOCARCINOMA; STOMACH MUCOSA; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; ENZYME ACTIVATION; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; HAPLORHINI; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLY(ADP-RIBOSE) POLYMERASES; PROTEINS; STOMACH; TUMOR CELLS, CULTURED;

ANIMALIA; HELICOBACTER; HELICOBACTER PYLORI; MACACA MULATTA;

EID: 0036286129     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1286-4579(02)01591-5     Document Type: Article

References (53)

1. Helicobacter pylori and cell proliferation of the gastric mucosa: Possible implications for gastric carcinogenesis
2. Apoptosis in gastric epithelial cells is induced by Helicobacter pylori and accompanied by increased expression of BAK
3. Helicobacter pylori infection does not increase gastric antrum mucosal cell proliferation
4. The effect of class II major histocompatibility complex expression on adherence of Helicobacter pylori and induction of apoptosis in gastric epithelial cells: A mechanism for T helper cell type 1-mediated damage
5. Increase in proliferation and apoptosis of gastric epithelial cells early in the natural history of Helicobacter pylori infection
6. Induction of gastric epithelial apoptosis by Helicobacter pylori
7. Helicobacter pylori virulence and genetic geography
8. Proliferation and apoptosis in gastric antral epithelial cells of patients infected with Helicobacter pylori
9. Disease-specific Helicobacter pylori virulence factors: The unfulfilled promise
10. Relationship of Helicobacter pylori CagA status to gastric cell proliferation and apoptosis
11. Increased gastric epithelial cell apoptosis associated with colonization with cagA+ Helicobacter pylori strains
12. Helicobacter pylori induces apoptosis in gastric mucosa through an upregulation of Bax expression in humans
13. Helicobacter pylori inhibits gastric cell cycle
14. Helicobacter pylori inhibits the G1 to S transition in AGS gastric epithelial cells
15. Regulation of apoptosis by differential expression of waf1, p53 and bcl2 in gastric epithelial cells exposed to Helicobacter pylori
16. Epithelial intestinal cell apoptosis induced by Helicobacter pylori depends on expression of the cag pathogenicity island phenotype
17. Mechanisms and genes of cellular suicide
18. Caspases: The executioners of apoptosis
19. Caspases: Intracellular signaling by proteolysis
20. The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32
21. Transient poly(ADP-ribosyl)ation of nuclear proteins and role of poly(ADP-ribose) polymerase in the early stages of apoptosis
22. Proteolysis of poly(ADP-ribose) polymerase by caspase 3: Kinetics of cleavage of mono(ADP-ribosyl)ated and DNA-bound substrates
23. The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis
24. Inhibition of apoptosis-associated DNA fragmentation activity in nonapoptotic cells: The role of DNA fragmentation factor-45 (DFF45/ICAD)
25. Cytosolic nuclease activated by caspase-3 and inhibited by DFF-45
26. CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45
27. Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria
28. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
29. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
30. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
31. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
32. Host specificity of Helicobacter pylori strains and host responses in experimentally challenged nonhuman primates
33. Transient and persistent experimental infection of nonhuman primates with Helicobacter pylori: Implications for human disease
34. Helicobacter pylori strain-specific genotypes and modulation of the gastric epithelial cell cycle
35. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
36. Activation of caspase 3 during Legionella pneumophila-induced apoptosis
37. Recruitment of apoptotic cysteine proteases (caspases) in influenza virus-induced cell death
38. Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis
39. Salmonella typhimurium invasion induces apoptosis in infected macrophages
40. Caspase-dependent apoptosis during infection with Cryptosporidium parvum
41. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
42. Virulence factors of Helicobacter pylori in Korean isolates do not influence proinflammatory cytokine gene expression and apoptosis in human gastric epithelial cells, nor do these factors influence the clinical outcome
43. Apoptotic signaling pathway activated by Helicobacter pylori infection and increase of apoptosis-inducing activity under serum-starved conditions
44. NF-kappa B-dependent inhibition of apoptosis is essential for host cell survival during Rickettsia rickettsii infection
45. Inhibition of apoptosis in chlamydia-infected cells: Blockade of mitochondrial cytochrome c release and caspase activation
46. Helicobacter pylori causes DNA damage in gastric epithelial cells
47. Influence of Helicobacter pylori on reactive oxygen-induced gastric epithelial cell injury
48. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
49. Differential modulation of apoptosis sensitivity in CD95 type I and type II cells
50. Country-specific constancy by age in cagA+ proportion of Helicobacter pylori infections
51. The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
52. Biochemical pathways of caspase activation during apoptosis
53. The modulation of host cell apoptosis by intracellular bacterial pathogens