Helicobacter pylori cagA+ strains and dissociation of gastric epithelial cell proliferation from apoptosis

Journal of the National Cancer Institute

Volumn 89, Issue 12, 1997, Pages 863-868

  Peek Jr , Richard M ^a,b   Moss, Steven F ^c   Tham, Kyi T ^a,b   Pérez Pérez, Guillermo I ^a   Wang, Shaobai ^c   Miller, Geraldine G ^a   Atherton, John C ^a   Holt, Peter R ^c   Blaser, Martin J ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DEPARTMENT OF VETERANS AFFAIRS   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; ARTICLE; BACTERIAL VIRULENCE; CANCER RISK; CELL PROLIFERATION; CHRONIC GASTRITIS; DISEASE ASSOCIATION; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; RISK ASSESSMENT; STOMACH CANCER; STOMACH EPITHELIUM; STRAIN DIFFERENCE;

EID: 1842331503     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/89.12.863     Document Type: Article

References (36)

1. Morris A, Nicholson G. Ingestion of Campylobacter pyloridis causes gastritis and raised fasting gastric pH. Am J Gastroenterol 1987; 82:192-9.
2. Marshall BJ, Armstrong JA, McGechie DB, Glancy RJ. Attempt to fulfill Koch's postulates for pyloric Campylobacter. Med J Aust 1985; 142:436-9.
3. Dooley CP, Cohen H, Fitzgibbons PL, Appleman MD, Perez-Perez GI, Blaser MJ. Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med 1989;321:1562-6.
4. Karnes WE Jr, Samloff IM, Siurala M, Kekki M, Sipponen P, Kim SW, et al. Positive serum antibody and negative tissue staining for Helicobacter pylori in subjects with atrophic body gastritis. Gastroenterology 1991;101:167-74.
5. Nomura A, Stemmermann GN, Chyou P, Kato I, Perez-Perez GI, Blaser MJ. Helicobacter pylori infection and gastric carcinoma in a population of Japanese Americans in Hawaii. N Engl J Med 1991;325:1132-6.
6. Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, et al. Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 1991;325: 1127-31.
7. Correa P. Human gastric carcinogenesis: a multistep and multifactorial process-First American Cancer Society Award Lecture on cancer epidemiology and prevention. Cancer Res 1996;52:6735-40.
8. Forman D. Helicobacter pylori infection: a novel risk factor in the etiology of gastric cancer [editorial]. J Natl Cancer Inst 1991; 83:1702-3.
9. Kuipers EJ, Perez-Perez GI, Meuwissen SG, Blaser MJ. Helicobacter pylori and atrophic gastritis: importance of the cagA status. J Natl Cancer Inst 1995;87:1777-80.
10. Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, et al. Infection with Helicobacter pylori strains possessing cagA associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995;55:2111-5.
11. Crabtree JE, Wyatt JI, Sobala GM, Miller G, Tompkins DS, Primrose JN, et al. Systemic and mucosal humoral responses to Helicobacter pylori in gastric cancer. Gut 1993;34:1339-43.
12. Atherton JC, Cao P, Peek RM Jr, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995;270:17771-7.
13. Bechi P, Balzi M, Becciolini A, Maugeri A, Raggi CC, Amorosi A, et al. Helicobacter pylori and cell proliferation of the gastric mucosa: possible implications for gastric carcinogenesis. Am J Gastroenterol 1996;91:271-6.
14. Fraser AG, Sim R, Sankey EA, Dhillon AP, Pounder RE. Effect of eradication of Helicobacter pylori on gastric epithelial cell proliferation. Aliment Pharmacol Ther 1994;8:167-73.
15. Crabtree JE, Taylor JD, Wyatt JI, Heatley RV, Shallcross TM, Tompkins DS, et al. Mucosal IgA recognition of Helicobacter pylori 120 kDa protein, peptic ulceration, and gastric pathology. Lancet 1991;338:332-5.
16. + Helicobacter pylori strains. Lab Invest 1995;71:760-70.
17. Moss SF, Calam J, Agarwal B, Wang S, Holt PR. Induction of gastric epithelial apoptosis by Helicobacter pylori. Gut 1996;38:498-501.
18. Mannick EE, Bravo LE, Zarama G, Realpe JL, Zhang XJ, Ruiz B, et al. Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res 1996;56:3238-43.
19. Vaux DL, Strasser A. The molecular biology of apoptosis. Proc Natl Acad Sci U S A 1996; 93:2239-44.
20. Perez-Perez GI, Dworkin BM, Chodos JE, Blaser MJ. Campylobacter pylori antibodies in humans. Ann Intern Med 1988;109:11-7.
21. Gray SF, Wyatt JI, Rathbone BJ. Simplified techniques for identifying Campylobacter pyloridis [letter]. J Clin Pathol 1986;39:1279.
22. Maniatis T, Fritsch EF, Sambrook J. Molecular cloning: a laboratory manual. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory, 1982.
23. Tummuru MK, Cover TL, Blaser MJ. Cloning and expression of a high-molecular-mass major antigen of Helicobacter pylori: evidence of linkage to cytotoxin production. Infect Immun 1993;61:1799-809.
24. Cattoretti G, Becker MH, Key G, Duchrow M, Schluter C, Galle J, et al. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections. J Pathol 1992;168: 357-63.
25. Thompson CB. Apoptosis in the pathogenesis and treatment of disease. Science 1995;267: 1456-62.
26. Que FG, Gores GJ. Cell death by apoptosis: basic concepts and disease relevance for the gastroenterologist. Gastroenterology 1996;110: 1238-43.
27. Bedi A, Pasricha PJ, Akhtar AJ, Barber JP, Bedi GC, Giardiello FM, et al. Inhibition of apoptosis during development of colorectal cancer. Cancer Res 1995;55:1811-6.
28. Moss SF, Scholes JV, Holt PR. Abnormalities of epithelial apoptosis in multistep colorectal neoplasia demonstrated by terminal deoxyuridine nick end labeling. Dig Dis Sci 1996;41: 2238-47.
29. Chow KW, Bank S, Ahn J, Roberts J, Blumstein M, Kranz V. Helicobacter pylori infection does not increase gastric antrum mucosal cell proliferation. Am J Gastroenterol 1995;90: 64-6.
30. Chen Y, Zychlinsky A. Apoptosis induced by bacterial pathogens. Microb Pathog 1994;17: 203-12.
31. Crabtree JE, Shallcross TM, Heatley RV, Wyatt JI. Mucosal tumour necrosis factor alpha and interleukin-6 in patients with Helicobacter pylori associated gastritis. Gut 1991;32: 1473-7.
32. Beg AA, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science 1996;274:782-4.
33. Wang CY, Mayo MW, Baldwin AS Jr. TNF-and cancer therapy-induced apoptosis: potentiation by inhibition of NF-κB. Science 1996; 274:784-7.
34. Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM. Suppression of TNF-α-induced apoptosis by NF-κB. Science 1996; 274:787-9.
35. + Helicobacter pylori strains induce enhanced activation of transcription factor NF-κB in gastric epithelial cells. J Leuk Biol 1995;28(Suppl):A134.
36. Munzenmaier A, Pahl HL, Covacci A, Bereswill S, Baeuerle PA, Kist M. Helicobacter pylori activates transcription factor NF-κB in CATO-III cells. Gut 1996;39:A-55.