Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 423, Issue 1-2, 1999, Pages 91-101

  Qu, Guang Zhi ^a   Dubeau, Louis ^b   Narayan, Ajita ^a   Yu, Mimi C ^b   Ehrlich, Melanie ^a  

^a TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Chromosome rearrangement; DNA hypomethylation; Heterochromatin; Ovarian cancer

Indexed keywords

SATELLITE DNA;

ARTICLE; CENTROMERE; CHROMOSOME 1; CHROMOSOME 16; CONTROLLED STUDY; CYSTADENOMA; DNA METHYLATION; DNA SEQUENCE; FEMALE; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; NUMERICAL CHROMOSOME ABERRATION; OVARY TUMOR; PRIORITY JOURNAL; STRUCTURAL CHROMOSOME ABERRATION;

5-METHYLCYTOSINE; CARCINOMA; CELL TRANSFORMATION, NEOPLASTIC; CENTROMERE; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 16; CYTOSINE; DNA METHYLATION; DNA, NEOPLASM; DNA, SATELLITE; FEMALE; HUMANS; OVARIAN NEOPLASMS;

EID: 0001992028     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(98)00229-2     Document Type: Article

References (55)

1. S. Heim, F. Mitelman, Cancer Cytogenetics, Wiley-Liss, New York, 1995.
2. V. Brito-Babapulle, N.B. Atkin, Break points in chromosome #1 abnormalities of 218 human neoplasms, Cancer Genet. Cytogenet. 4 (1981) 215-225.
3. O. Oliveros, E. Yunis, Chromosome evolution in retinoblastoma, Cancer Genet. Cytogenet. 82 (1995) 155-160.
4. F. Mertens, B. Johansson, M. Hoglund, F. Mitelman, Chromosomal imbalance maps of malignant solid tumors: a cytogenetic survey of 3185 neoplasms, Cancer Res. 57 (1997) 2765-2780.
5. H. Iwabuchi, M. Sakamoto, H. Sakunaga, Y.Y. Ma, M.L. Carcangiu, D. Pinkel, T.L. Yang-Feng, J.W. Gray, Genetic analysis of benign, low-grade, and high-grade ovarian tumors, Cancer Res. 55 (1995) 6172-6180.
6. M. Steenman, B. Redeker, M. de Meulemeester, K. Wiesmeijer, P.A. Voute, A. Westerveld, R. Slater, M. Mannens, Comparative genomic hybridization analysis of Wilms tumors, Cytogenet. Cell Genet. 77 (1997) 296-303.
7. M. Jeanpierre, C. Turleau, A. Aurias, M. Prieur, F. Ledeist, A. Fischer, E. Viegas-Pequignot, An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome, Hum. Molec. Genet. 2 (1993) 731-735.
8. P. Miniou, M. Jeanpierre, V. Blanquet, V. Sibella, D. Bonneau, C. Herbelin, A. Fischer, A. Niveleau, E.T. Viegas-Pequignot, Abnormal methylation pattern in constitutive and facultative (X inactive chromosome) heterochromatin of ICF patients, Hum. Molec. Genet. 3 (1994) 2093-2102.
9. D.F.C.M. Smeets, U. Moog, C.M.R. Weemaes, G. Vaes-Peeters, G.F.M. Merkx, J.P. Niehof, G. Hamers, ICF syndrome: a new case and review of the literature, Hum. Genet. 94 (1994) 240-246.
10. D. Kipling, P.E. Warburton, Centromeres, CENP-B and Tigger too, Trends Genet. 13 (1997) 141-145.
11. A.R. Mitchell, P. Jeppesen, L. Nicol, H. Morrison, D. Kipling, Epigenetic control of mammalian centromere protein binding: does DNA methylation have a role?, J. Cell. Sci. 109 (1996) 2199-2206.
12. X. Nan, P. Tate, E. Li, A. Bird, DNA methylation specifies chromosomal localization of MeCP2, Mol. Cell. Biol. 16 (1996) 414-421.
13. N. Pandis, Y. Jin, L. Gorunova, C. Petersson, G. Bardi, I. Idvall, B. Johansson, C. Ingvar, N. Mandahl, F. Mitelman, S. Heim, Chromosome analysis of 97 primary breast carcinomas: identification of eight karyotypic subgroups, Genes Chrom. Cancer 12 (1995) 173-185.
14. M.J. Tymms, A.Y. Ng, R.S. Thomas, B.C. Schutte, J. Zhou, H.J. Eyre, G.R. Sutherland, A. Seth, M. Rosenberg, T. Papas, C. Debouck, I. Kola, A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer, Oncogene 15 (1997) 2449-2462.
15. I. Bieche, M.-H. Champeme, R. Lidereau, A tumor suppressor gene on chromosome 1p32-pter controls the amplification of MYC family genes in breast cancer, Cancer Res. 54 (1994) 4274-4276.
16. H. Enomoto, T. Ozaki, E. Takahashi, N. Nomura, S. Tabata, H. Takahashi, N. Ohnuma, M. Tanabe, J. Iwai, H. Yoshida et al., Identification of human DAN gene, mapping to the putative neuroblastoma tumor suppressor locus, Oncogene 9 (1994) 2785-2791.
17. I. Newsham, A. Kindler-Rohrborn, D. Daub, W. Cavenee, A constitutional BWS-related t(11;16) chromosome translocation occurring in the same region of chromosome 16 implicated in Wilms tumors, Genes Chrom. Cancer 12 (1995) 1-7.
18. F.H. Thompson, J. Emerson, D. Alberts, Y. Liu, X.Y. Guan, A. Burgess, S. Fox, R. Taetle, R. Weinstein, R. Makar et al., Clonal chromosome abnormalities in 54 cases of ovarian carcinoma, Cancer Genet. Cytogenet. 73 (1994) 33-45.
19. M. Kiechle-Schwarz, T. Bauknecht, J. Schmidt, L. Walz, A. Pfleiderer, Recurrent cytogenetic aberrations in human ovarian carcinomas, Cancer Detect. Prev. 19 (1995) 234-243.
20. R.B. Deger, S.A. Faruqi, J.S. Noumoff, Karyotypic analysis of 32 malignant epithelial ovarian tumors, Cancer Genet. Cytogenet. 96 (1997) 166-173.
21. F. Mitelman, B. Johansson, F. Mertens, Catalog of Chromosome Aberrations in Cancer, Wiley-Liss, New York, 1994.
22. P. Cheng, C. Schmutte, K.F. Cofer, J.C. Felix, M.C. Yu, L. Dubeau, Alterations in DNA methylation are early, but not initial, events in ovarian tumorigenesis, Br. J. Cancer 75 (1997) 396-402.
23. A. Almeida, N. Kokalj-Vokac, D. Lefrancois, E. ViegasPequignot, M. Jeanpierre, B. Dutrillaux, B. Malfoy, Hypomethylation of classical satellite DNA and chromosome instability in lymphoblastoid cell lines, Hum. Genet. 91 (1993) 538-546.
24. R.K. Moyzis, K.L. Albright, M.F. Bartholdi, L.S. Cram, L.L. Deaven, C.E. Hildebrand, N.E. Joste, J.L. Longmire, J. Meyne, T. Schwarzacher-Robinson, Human chromosomespecific repetitive DNA sequences: novel markers for genetic analysis, Chromosoma 95 (1987) 375-386.
25. J.S. Waye, S.J. Durfy, D. Pinkel, S. Kenwrick, M. Patterson, K.E. Davies, H.F. Willard, Chromosome-specific alpha satellite DNA from human chromosome: 1. Hierarchical structure and genomic organization of polymorphic domain spanning several hundred kilobase pairs of centromeric DNA, Genomics 1 (1987) 43-51.
26. W. Ji, R. Hernandez, X.-Y. Zhang, G. Qu, A. Frady, M. Varela, M. Ehrlich, DNA demethylation and pericentromeric rearrangements of chromosome 1, Mutat. Res. 379 (1997) 33-41.
27. G. Snedecor, W. Cochran, Statistical Methods, 6th edn., The Iowa State Univ. Press, Ames, IA, 1967.
28. L. Dubeau, The cell of origin of ovarian epithelial tumors and the ovarian surface epithelium dogma: does the emperor have no clothes?, Gynecol. Oncol., in press, 1998.
29. M.A. Gama-Sosa, R.Y.-H. Wang, K.C. Kuo, C.W. Gehrke, M. Ehrlich, The 5-methylcytosine content of highly repeated sequences in human DNA, Nucleic Acids Res. 11 (1983) 3087-3095.
30. S. Feinstein, V.R. Racaniello, M. Ehrlich, C.W. Gehrke, D.A. Miller, O.J. Miller, Pattern of undermethylation of the major satellite DNA of mouse sperm, Nucleic Acids Res. 13 (1985) 3969-3978.
31. V. Chapman, L. Forrester, J. Sanford, N. Hastie, J. Rossant, Cell lineage-specific undermethylation of mouse repetitive DNA, Nature 307 (1984) 284-286.
32. J. Diebold, I. Deisenhofer, G.B. Baretton, S. Blasenbreu, B. Suchy, K. Schneiderbanger, W. Meier, C.J. Haas, U. Lohrs, Interphase cytogenetic analysis of serous ovarian tumors of low malignant potential: comparison with serous cystadenomas and invasive serous carcinomas, Lab. Invest. 75 (1996) 473-485.
33. G. Chenevix-Trench, J. Kerr, T. Hurst, Y.C. Shih, D. Purdie, L. Bergman, M. Friedlander, B. Sanderson, A. Zournazi, T. Coombs, J.A. Leary, E. Crawford, A.N. Shelling, I. Cooke, T.S. Ganesan, J. Searle, C. Choi, J.C. Barrett, S.K. Khoo, B. Ward, Analysis of loss of heterozygosity and KRAS2 mutations in ovarian neoplasms: clinicopathological correlations, Genes Chrom. Cancer 18 (1997) 75-83.
34. C.-L. Hsieh, M.R. Lieber, CpG methylated minichromosomes become inaccessible for V(D)J recombination after undergoing replication, EMBO J. 11 (1996) 315-325.
35. L.L. McCluskey, L. Dubeau, Biology of ovarian cancer, Curr. Opin. Oncol. 9 (1997) 465-470.
36. J. Zheng, W.F. Benedict, H.J. Xu, S.X. Hu, T.M. Kim, M. Velicescu, M. Wan, K.F. Cofer, L. Dubeau, Genetic disparity between morphologically benign cysts contiguous to ovarian carcinomas and solitary cystadenomas, J. Natl. Cancer Inst. 87 (1995) 1146-1153.
37. A.P. Feinberg, C.W. Gehrke, K.C. Kuo, M. Ehrlich, Reduced genomic 5-methylcytosine content in human colonie neoplasia, Cancer Res. 48 (1988) 1159-1161.
38. P.C. Cheng, J.A. Gosewehr, T.M. Kim, M. Velicescu, M. Wan, J. Zheng, J.C. Felix, K.F. Cofer, P. Luo, B.H. Biela, G. Godorov, L. Dubeau, Potential role of the inactivated X chromosome in ovarian epithelial tumor development, J. Natl. Cancer Inst. 88 (1996) 510-518.
39. G. Qu, P.E. Grundy, A. Narayan, M. Ehrlich, Frequent hypomethylation in Wilms tumors of pericentromeric DNA in chromosomes 1 and 16, Cancer Genet. Cytogenet., in press, 1998.
40. C. Davey, S. Pennings, J. Allan, CpG methylation remodels chromatin structure in vitro, J. Mol. Biol. 267 (1997) 276-288.
41. T. Haaf, The effects of 5-azacytidine and 5-azadeoxycytidine on chromosome structure and function: implications for methylation-associated cellular processes, Pharm. Ther. 65 (1995) 19-46.
42. S.U. Kass, N. Landsberger, A.P. Wolffe, DNA methylation directs a time-dependent repression of transcription initiation, Curr. Biol. 7 (1997) 157-165.
43. P.L. Jones, G.J. Veenstra, P.A. Wade, D. Vermaak, S.U. Kass, N. Landsberger, J. Strouboulis, A.P. Wolffe, Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription, Nat. Genet. 19 (1998) 187-191.
44. S. Schuffenhauer, O. Bartsch, M. Stumm, T. Buchholz, T. Petropoulou, S. Kraft, B. Belohradsky, T. Meitinger, R. Wegner, DNA, FISH and complementation studies in ICF syndrome; DNA hypomethylation of repetitive and single copy loci and evidence for a trans acting factor, Hum. Genet. 96 (1995) 562-571.
45. N. Kokalj-Vokac, A. Almeida, V.-P.E.M. Jeanpierre, B. Malfoy, Specific induction of uncoiling and recombination by azacytidine in classical satellite-containing constitutive heterochromatin, Cytogenet. Cell Genet. 63 (1993) 11-15.
46. R. Hernandez, A. Frady, X.-Y. Zhang, M. Varela, M. Ehrlich, Preferential induction of chromosome 1 multibranched figures and whole-arm deletions in a human pro-B cell line treated with 5-azacytidine or 5-azadeoxycytidine, Cytogenet. Cell Genet. 76 (1997) 196-201.
47. R.Z. Chen, U. Pettersson, C. Beard, L. Jackson-Grusby, R. Jaenisch, DNA hypomethylation leads to elevated mutation rates, Nature 395 (1998) 89-93.
48. R. Singal, R. Ferris, J.A. Little, S.Z. Wang, G.D. Cinder, Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells, Proc. Natl. Acad. Sci. USA 94 (1997) 13724-13729.
49. M.A. Gama-Sosa, V.A. Slagel, R.W. Trewyn, R. Oxenhandler, K.C. Kuo, C.W. Gehrke, M. Ehrlich, The 5-methylcytosine content of DNA from human tumors, Nucleic Acids Res. 11 (1983) 6883-6894.
50. J. Bernardino, C. Roux, A. Almeida, N. Vogt, A. Gibaud, M. Gerbault-Seureau, H. Magdelenat, C.A. Bourgeois, B. Malfoy, B. Dutrillaux, DNA hypomethylation in breast cancer: an independent parameter of tumor progression?, Cancer Genet. Cytogenet. 97 (1997) 83-89.
51. J.G. Herman, A. Merlo, L. Mao, R.G. Lapidus, J.P. Issa, N.B. Davidson, D. Sidransky, S.B. Baylin, Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers, Cancer Res. 55 (1995) 4525-4530.
52. J.R. Graff, J.G. Herman, R.G. Lapidus, H. Chopra, R. Xu, D.F. Jarrard, W.B. Isaacs, P.M. Pitha, N.B. Davidson, S.B. Baylin, E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas, Cancer Res. 55 (1995) 5195-5199.
53. M. Jeanpierre, Human satellite 2 and 3, Annu. Rev. Genet. 37 (1994) 163-171.
54. B. Vissel, K.H. Choo, Human alpha satellite DNA-consensus sequence and conserved regions, Nucleic Acids Res. 15 (1987) 6751-6752.
55. M. Ehrlich, M.A. Gama-Sosa, L.H. Huang, R.M. Midgett, K.C. Kuo, R.A. McCune, C. Gehrke, Amount and distribution of 5-methylcytosine in human DNA from different types of tissues or cells, Nucleic Acids Res. 10 (1982) 2709-2721.