Differential methylation of human LINE-1 retrotransposons in malignant cells

Gene

Volumn 176, Issue 1-2, 1996, Pages 39-44

  Alves, Gilda ^a,b   Tatro, Alicia ^a   Fanning, Thomas ^a  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

Author keywords

Cancer; Long interspersed element; Methylcytosine

Indexed keywords

ARTICLE; BREAST CANCER; CANCER CELL; CELL LINE; CHROMOSOME 15; CONTROLLED STUDY; DNA FLANKING REGION; DNA METHYLATION; DNA SEQUENCE; GENE LOCUS; GERM CELL; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROPOSON; SEQUENCE HOMOLOGY; SOMATIC CELL; SOUTHERN BLOTTING;

HOMO SAPIENS;

EID: 0030591769     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-1119(96)00205-3     Document Type: Article

References (19)

1. Bishop, J.M. (1991) Molecular themes in oncogenesis. Cell 64, 235-248.
2. Bratthauer, G.L. and Fanning, T.G. (1992) Active LINE-1 retrotransposons in human testicular cancer. Oncogene 7, 507-510.
3. Bratthauer, G.L. and Fanning, T.G. (1993) LINE-1 retrotransposon expression in pediatric germ cell tumors. Cancer 71, 2383-2386.
4. Bratthauer, G.L., Cardiff, R.D. and Fanning, T.G. (1994) Expression of LINE-1 retrotransposons in human breast cancer. Cancer 73, 2333-2336.
5. Cooper, G.M. (1990) Oncogenes. Jones and Bartlett, Boston.
6. Dubois, B.L. and Naylor, S.L. (1993) Characterization of NIGMS human/rodent somatic cell hybrid mapping panel 2 by PCR. Genomics 16, 315-319.
7. Fanning, T.G. and Singer, M.F. (1987) LINE-1: a mammalian transposable element. Biochim. Biophys. Acta 910, 203-212.
8. Feinberg, A.P. and Vogelstein, B. (1983) Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301, 89-92.
9. Goelz, S.E., Vogelstein, B., Hamilton, S.R. and Feinberg, A.P. (1985) Hypomethylation of DNA from benign and malignant human colon neoplasias. Science 228, 187-190.
10. Hutchison, C.A., Hardies, S.C., Loeb, D.D., Shehee, W.R. and Edgell, M.H. (1989) LINEs and related retroposons: long interspersed repeated sequences in the eucaryotic genome. In: Berg, D.E. and Howe, M.M. (Eds.), Mobile DNA. American Society for Microbiology, Washington, pp. 593-636.
11. Kallioniemi, A., Kallioniemi, O.-P., Piper, J., Tanner, M., Stokke, T., Chen, L., Smith, H.S., Pinkel, D., Gray, J.W. and Waldman, F.M. (1994) Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. Proc. Natl. Acad. Sci. USA 91, 2156-2160.
12. Kazazian, H.H., Wong, C., Youssoufian, H., Scott, A.F., Phillips, D.G. and Antonarakis, S. (1988) Hemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man. Nature 332, 164-166.
13. Kovalic, D., Kwak, J.-H. and Weisblum, B. (1991) Method for direct cloning of DNA fragments generated by the polymerase chain reaction. Nucleic Acids Res. 19, 4560.
14. Martin, S.L. (1991) LINEs. Curr. Opin. Genet. Dev. 1, 505-508.
15. Miki, Y., Nishisho, I., Horii, A., Miyoshi, Y., Utsunomiya, J., Kinzler, K.W., Vogelstein, B. and Nakamura, Y. (1992) Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer. Cancer Res. 52, 643-645.
16. Morse, B., Rothberg, P.G., South, V.J., Spandorfer, J.M. and Astrin, S.M. (1988) Insertion mutagenesis of the myc locus by LINE-1 sequences in a human breast carcinoma. Nature 333, 87-90.
17. Thayer, R.E., Singer, M.F. and Fanning, T.G. (1993) Undermethylation of LINE-1 sequences in human cells producing a LINE-1-encoded protein. Gene 133, 273-277.
18. Weinberg, R.A. (Ed.) (1989) Oncogenes and the Molecular Origins of Cancer. Cold Spring Harbor Laboratory Press, New York.
19. Weiss, R., Teich, N., Varmus, H. and Coffin, J. (1982) RNA Tumor Viruses. Cold Spring Harbor Laboratory, New York.