-
3
-
-
0013526704
-
Shortening of life and causes of death in mice exposed to single whole-body dose of radiation
-
Lindop P.J., Rotblat J. Shortening of life and causes of death in mice exposed to single whole-body dose of radiation. Nature. 189:1961;645-648.
-
(1961)
Nature
, vol.189
, pp. 645-648
-
-
Lindop, P.J.1
Rotblat, J.2
-
5
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 11:1956;298-300.
-
(1956)
J. Gerontol.
, vol.11
, pp. 298-300
-
-
Harman, D.1
-
6
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
Hayflick L., Moorhead P.S. The serial cultivation of human diploid cell strains. Exp. Cell Res. 25:1961;585-621.
-
(1961)
Exp. Cell Res.
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
7
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37:1965;614-636.
-
(1965)
Exp. Cell Res.
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
8
-
-
73649150958
-
The maintenance of the accuracy of protein synthesis and its relevance to ageing
-
Orgel L.E. The maintenance of the accuracy of protein synthesis and its relevance to ageing. Proc. Natl. Acad. Sci. U. S. A. 49:1963;517-521.
-
(1963)
Proc. Natl. Acad. Sci. U. S. A.
, vol.49
, pp. 517-521
-
-
Orgel, L.E.1
-
9
-
-
0014966610
-
Mistranslation and ageing in Neurospora
-
Lewis C.M., Holliday R. Mistranslation and ageing in Neurospora. Nature. 288:1970;877-880.
-
(1970)
Nature
, vol.288
, pp. 877-880
-
-
Lewis, C.M.1
Holliday, R.2
-
10
-
-
0015496897
-
Altered enzymes in ageing human fibroblasts
-
Holliday R., Tarrant G.M. Altered enzymes in ageing human fibroblasts. Nature. 238:1972;26-30.
-
(1972)
Nature
, vol.238
, pp. 26-30
-
-
Holliday, R.1
Tarrant, G.M.2
-
11
-
-
0015932795
-
Ageing of clones of mammalian cells
-
Orgel L.E. Ageing of clones of mammalian cells. Nature. 243:1973;441-445.
-
(1973)
Nature
, vol.243
, pp. 441-445
-
-
Orgel, L.E.1
-
12
-
-
84883833036
-
Aneuploidy in the degenerative phase of serial cultivation of human cell strains
-
Saksela E., Moorhead P.S. Aneuploidy in the degenerative phase of serial cultivation of human cell strains. Proc. Natl. Acad. Sci. U. S. A. 50:1963;390-395.
-
(1963)
Proc. Natl. Acad. Sci. U. S. A.
, vol.50
, pp. 390-395
-
-
Saksela, E.1
Moorhead, P.S.2
-
13
-
-
0342750060
-
Senescence and the fidelity of protein synthesis in Drosophila
-
Harrison B.J., Holliday R. Senescence and the fidelity of protein synthesis in Drosophila. Nature. 213:1967;990-992.
-
(1967)
Nature
, vol.213
, pp. 990-992
-
-
Harrison, B.J.1
Holliday, R.2
-
14
-
-
0014694440
-
Errors in protein synthesis and clonal senescence in fungi
-
Holliday R. Errors in protein synthesis and clonal senescence in fungi. Nature. 221:1969;1224-1228.
-
(1969)
Nature
, vol.221
, pp. 1224-1228
-
-
Holliday, R.1
-
15
-
-
0016840454
-
A rapid rise in cell variants during the senescence of populations of human fibroblasts
-
Fulder S.J., Holliday R. A rapid rise in cell variants during the senescence of populations of human fibroblasts. Cell. 6:1975;67-73.
-
(1975)
Cell
, vol.6
, pp. 67-73
-
-
Fulder, S.J.1
Holliday, R.2
-
16
-
-
0019274638
-
Senescence of cultured human diploid fibroblasts: Are mutations responsible?
-
Gupta R.S. Senescence of cultured human diploid fibroblasts: are mutations responsible? J. Cell Physiol. 103:1980;209-216.
-
(1980)
J. Cell Physiol.
, vol.103
, pp. 209-216
-
-
Gupta, R.S.1
-
17
-
-
0017159508
-
Decreased fidelity of DNA polymerase activity isolated from ageing human fibroblasts
-
Linn S., Kairis M., Holliday R. Decreased fidelity of DNA polymerase activity isolated from ageing human fibroblasts. Proc. Natl. Acad. Sci. U. S. A. 73:1976;2818-2822.
-
(1976)
Proc. Natl. Acad. Sci. U. S. A.
, vol.73
, pp. 2818-2822
-
-
Linn, S.1
Kairis, M.2
Holliday, R.3
-
18
-
-
0019880374
-
Increased error frequency of DNA polymerases from senescent human fibroblasts
-
Murray V., Holliday R. Increased error frequency of DNA polymerases from senescent human fibroblasts. J. Mol. Biol. 146:1981;55-76.
-
(1981)
J. Mol. Biol.
, vol.146
, pp. 55-76
-
-
Murray, V.1
Holliday, R.2
-
19
-
-
0020473253
-
Changes in DNA polymerases α, β and γ during the replicative life-span of cultured human fibroblasts
-
Krauss S.W., Linn S. Changes in DNA polymerases α, β and γ during the replicative life-span of cultured human fibroblasts. Biochemistry. 21:1982;1002-1009.
-
(1982)
Biochemistry
, vol.21
, pp. 1002-1009
-
-
Krauss, S.W.1
Linn, S.2
-
20
-
-
36949073539
-
A theory of ageing
-
Maynard Smith J. A theory of ageing. Nature. 184:1959;956-957.
-
(1959)
Nature
, vol.184
, pp. 956-957
-
-
Maynard Smith, J.1
-
21
-
-
0010804575
-
The causes of ageing
-
Maynard Smith J. The causes of ageing. Proc. R. Soc. B. 157:1962;115-127.
-
(1962)
Proc. R. Soc. B
, vol.157
, pp. 115-127
-
-
Maynard Smith, J.1
-
22
-
-
0016647491
-
Chromosome changes during the in vitro ageing of MRC-5 human fibroblasts
-
Thompson K.V.A., Holliday R. Chromosome changes during the in vitro ageing of MRC-5 human fibroblasts. Exp. Cell Res. 96:1975;1-6.
-
(1975)
Exp. Cell Res.
, vol.96
, pp. 1-6
-
-
Thompson, K.V.A.1
Holliday, R.2
-
23
-
-
0018183683
-
The longevity of diploid and polyploid human fibroblasts: Evidence against the somatic mutation theory of cellular ageing
-
Thompson K.V.A., Holliday R. The longevity of diploid and polyploid human fibroblasts: evidence against the somatic mutation theory of cellular ageing. Exp. Cell Res. 112:1978;281-287.
-
(1978)
Exp. Cell Res.
, vol.112
, pp. 281-287
-
-
Thompson, K.V.A.1
Holliday, R.2
-
24
-
-
0018377134
-
A mortalisation theory for the control of cell proliferation and for the origin of immortal cell lines
-
Shall S., Stein W.D. A mortalisation theory for the control of cell proliferation and for the origin of immortal cell lines. J. Theor. Biol. 76:1979;219-231.
-
(1979)
J. Theor. Biol.
, vol.76
, pp. 219-231
-
-
Shall, S.1
Stein, W.D.2
-
25
-
-
0019778446
-
Predictions of the somatic mutation and mortalization theories of cellular ageing are contrary to experimental observations
-
Holliday R., Kirkwood T.B.L. Predictions of the somatic mutation and mortalization theories of cellular ageing are contrary to experimental observations. J. Theor. Biol. 93:1981;627-642.
-
(1981)
J. Theor. Biol.
, vol.93
, pp. 627-642
-
-
Holliday, R.1
Kirkwood, T.B.L.2
-
26
-
-
0000934386
-
Cytogenetic studies in leucocytes on the general population: Subjects of ages 65 years and more
-
Jacobs P.A., Brunton M., Court Brown W.M. Cytogenetic studies in leucocytes on the general population: subjects of ages 65 years and more. Ann. Hum. Genet. Lond. 27:1964;353-362.
-
(1964)
Ann. Hum. Genet. Lond.
, vol.27
, pp. 353-362
-
-
Jacobs, P.A.1
Brunton, M.2
Court Brown, W.M.3
-
27
-
-
0027930347
-
Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesis blocked lymphocytes
-
Fenech M., Neville S., Rinaldi J. Sex is an important variable affecting spontaneous micronucleus frequency in cytokinesis blocked lymphocytes. Mutat. Res. 313:1994;203-207.
-
(1994)
Mutat. Res.
, vol.313
, pp. 203-207
-
-
Fenech, M.1
Neville, S.2
Rinaldi, J.3
-
28
-
-
0018380453
-
Enumeration of 6-thioguanine resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo
-
Strauss G.H., Albertini R.J. Enumeration of 6-thioguanine resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo. Mutat. Res. 61:1979;353-379.
-
(1979)
Mutat. Res.
, vol.61
, pp. 353-379
-
-
Strauss, G.H.1
Albertini, R.J.2
-
29
-
-
0019861273
-
Induction of 8-azaguanine resistance and sister chromatid exchange in human lymphocytes exposed to mitomycin C and X-rays in vitro
-
Evans H.J., Vijaylaxmi Induction of 8-azaguanine resistance and sister chromatid exchange in human lymphocytes exposed to mitomycin C and X-rays in vitro. Nature. 292:1981;601-605.
-
(1981)
Nature
, vol.292
, pp. 601-605
-
-
Evans, H.J.1
Vijaylaxmi2
-
30
-
-
0020459885
-
Human lymphocytes resistant to 6-thioguanine increases with age
-
Morley A.A., Cox S., Holliday R. Human lymphocytes resistant to 6-thioguanine increases with age. Mech. Ageing Dev. 19:1982;21-26.
-
(1982)
Mech. Ageing Dev.
, vol.19
, pp. 21-26
-
-
Morley, A.A.1
Cox, S.2
Holliday, R.3
-
31
-
-
0026603009
-
In vivo human somatic mutation: Frequency and spectrum with age
-
Grist S.A., McCarron M., Kutlaca A., Turner D.R., Morley A.A. In vivo human somatic mutation: frequency and spectrum with age. Mutat. Res. 266:1992;189-196.
-
(1992)
Mutat. Res.
, vol.266
, pp. 189-196
-
-
Grist, S.A.1
McCarron, M.2
Kutlaca, A.3
Turner, D.R.4
Morley, A.A.5
-
32
-
-
0027400411
-
Effect of dietary restriction on in vivo somatic mutation in mice
-
Dempsey J.L., Pfeiffer M., Morley A.A. Effect of dietary restriction on in vivo somatic mutation in mice. Mutat. Res. 291:1993;141-145.
-
(1993)
Mutat. Res.
, vol.291
, pp. 141-145
-
-
Dempsey, J.L.1
Pfeiffer, M.2
Morley, A.A.3
-
33
-
-
0032408795
-
Somatic mutation and ageing
-
Morley A.A. Somatic mutation and ageing. Ann. N. Y. Acad. Sci. 854:1998;20-22.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.854
, pp. 20-22
-
-
Morley, A.A.1
-
35
-
-
0030470572
-
Neoplastic transformation: The contrasting stability of human and mouse cells
-
T. Lindahl. New York: Cold Spring Harbor Laboratory Press
-
Holliday R. Neoplastic transformation: the contrasting stability of human and mouse cells. Lindahl T. Genetic Instability in Cancer. Cancer Surveys. 28:1996;103-115 Cold Spring Harbor Laboratory Press, New York.
-
(1996)
Genetic Instability in Cancer. Cancer Surveys
, vol.28
, pp. 103-115
-
-
Holliday, R.1
-
37
-
-
0029131290
-
The somatic mutation theory of ageing
-
Morley A.A. The somatic mutation theory of ageing. Mutat. Res. 338:1995;19-23.
-
(1995)
Mutat. Res.
, vol.338
, pp. 19-23
-
-
Morley, A.A.1
-
38
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl T. Instability and decay of the primary structure of DNA. Nature. 362:1993;709-715.
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
39
-
-
0025827425
-
Mutations and epimutations in mammalian cells
-
Holliday R. Mutations and epimutations in mammalian cells. Mutat. Res. 250:1991;351-363.
-
(1991)
Mutat. Res.
, vol.250
, pp. 351-363
-
-
Holliday, R.1
-
40
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman K.B., Ames B.N. The free radical theory of aging matures. Physiol. Rev. 78:1998;547-581.
-
(1998)
Physiol. Rev.
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
41
-
-
0032425350
-
Mitochondrial mutations and age
-
Ozawa T. Mitochondrial mutations and age. Ann. N. Y. Acad. Sci. 854:1998;128-154.
-
(1998)
Ann. N. Y. Acad. Sci.
, vol.854
, pp. 128-154
-
-
Ozawa, T.1
-
42
-
-
0030028185
-
Somatic mutations are frequent and increase with age in human kidney epithelial cells
-
Martin G.M., Ogburn C.E., Colgin L.M., Gown A.M., Edland S.D., Monnat R.J. Somatic mutations are frequent and increase with age in human kidney epithelial cells. Hum. Mol. Genet. 5:1996;215-221.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 215-221
-
-
Martin, G.M.1
Ogburn, C.E.2
Colgin, L.M.3
Gown, A.M.4
Edland, S.D.5
Monnat, R.J.6
|