Up-regulation of inducible nitric oxide synthase in the substantia nigra by lipopolysaccharide causes microglial activation and neurodegeneration

Neurobiology of Disease

Volumn 12, Issue 1, 2003, Pages 35-45

  Arimoto, Toyoko ^a,b   Bing, Guoying ^a  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Inducible nitric oxide synthase; Inflammation; Lipopolysaccharide; Microglia; Neurodegeneration; Nitric oxide

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; DEXAMETHASONE; GLUCOCORTICOID; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; SUBSTANTIA NIGRA; UPREGULATION; WESTERN BLOTTING;

EID: 0037330339     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-9961(02)00017-7     Document Type: Article

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