Temporal, regional, and cell-specific changes of iNOS expression after intrastriatal microinjection of interferon gamma and bacterial lipopolysaccharide

Journal of Chemical Neuroanatomy

Volumn 18, Issue 4, 2000, Pages 167-179

  Heneka, Michael T ^a   Dumitrescu, Lucia ^a   Löschmann, Peter A ^a   Wüllner, Ulrich ^a   Klockgether, Thomas ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Astrocytes; ED1; Glial fibrillary acidic protein; In vivo; Inducible nitric oxide synthase; Microglia; Nitric oxide

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; GLIAL FIBRILLARY ACIDIC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL SPECIFICITY; CONTROLLED STUDY; CORPUS CALLOSUM; CORPUS STRIATUM; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME INDUCTION; ENZYME SYNTHESIS; EPITOPE MAPPING; MACROPHAGE ACTIVATION; MICROINJECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; ASTROCYTES; CORPUS CALLOSUM; CORPUS STRIATUM; GLIAL FIBRILLARY ACIDIC PROTEIN; IN SITU NICK-END LABELING; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MALE; MICROGLIA; MICROINJECTIONS; NEURITIS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, WISTAR; TYROSINE;

EID: 0034001158     PISSN: 08910618     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-0618(00)00041-7     Document Type: Article

References (43)

1. Becher B., Antel J.P. Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia. Glia. 18:1996;1-10.
2. Beckman J.S., Ye Y.Z., Anderson P.G., Chen J., Acavitti M.A., Tarpey M.M., White C.R. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol. Chem. Hoppe Seyler. 375:1994;81-88.
3. Benveniste, E.N., 1995. Cytokine production. In: Ransom, B., Kettenmann, H. (eds.), Neuroglia. Oxford University Press, New York, pp. 700-713.
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
5. Breder C.D., Hazuka C., Ghayur T., Klug C., Huginin M., Yasuda K., Teng M., Saper C.B. Regional induction of tumor necrosis factor α expression in the mouse brain after systemic lipopolysaccharide administration. Proc. Natl. Acad. Sci. USA. 91:1994;11393-11397.
6. Bredt D.S., Snyder S.H. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme. Proc. Natl. Acad. Sci. USA. 87:1990;682-685.
7. Buttery L.D., Evans T.J., Springall D.R., Carpenter A., Cohen J., Polak J.M. Immunochemical localization of inducible nitric oxide synthase in endotoxin treated rats. Lab-Invest. 71:1994;755-764.
8. Calka J., Wolf G., Schmitt W. Induction of cytosolic NADPH diaphorase/nitric oxide synthasein reactive microglia/macrophages after quiniolinic acid lesions in the rat striatum: an electron and light microscopical study. Histochem. Cell Biol. 105:1996;81-89.
9. Chao C.C., Hu S., Sheng W.S., Bu D., Bukrinsky M.I., Peterson P.K. Cytokine stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia. 16:1996;276-284.
10. Choi D.W., Koh J., Peters S. Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J. Neurosci. 8:1988;185-196.
11. Corradin S.B., Mauel J., Donini S.D., Quattrochi E., Ricciardi-Castagnoli P. Inducible nitric oxide synthase activity of cloned murine microglial cells. Glia. 7:1993;255-262.
12. Dawson T.M., Dawson V.L., Snyder S.H. A novel neuronal messenger molecule in brain: the free radical, nitric oxide. Ann. Neurol. 32:1992;297-311.
13. Dawson V.L., Brahmbhatt H.P., Mong J.A., Dawson T.M. Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology. 33:1994;1425-1430.
14. Dijkstra C.D., Döpp E.A., Joling P., Kraal G. The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology. 54:1985;589-599.
15. Ding M., St.-Pierre B.A., Parkinson J.F., Medberry P, Wong J.L., Rogers N.E., Ignarro L.J., Merrill J.E. Inducible nitric oxide synthase and nitric oxide production in human fetal astrocytes and microglia. A kinetic analysis. J. Biol. Chem. 272:1997;11327-11335.
16. Flaris N.A., Densmore T.L., Molleston M.C., Hickey W.F. Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction. Glia. 7:1993;34-40.
17. Frey E.A., Miller D.S., Jahr T.G., Sundan A., Bazil V., Espevik T., Finlay B.B., Wright S.D. Soluble CD 14 participates in the responses of cells to lipopolysaccharide. J. Exp. Med. 176:1992;1665-1671.
18. Galea E., Feinstein D.L., Reis D.J. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. USA. 89:1992;10945-10949.
19. Galea E., Reis D.J., Fox E.S., Xu H., Feinstein D.L. CD 14 mediates endotoxin induction of nitric oxide synthase in cultured brain glial cells. J. Neuroimmunol. 64:1996;19-28.
20. Garcion E., Sindji L., Montero-Menei C., Andre C., Brachet P., Darcy F. Expression of inducible nitric oxide synthase during rat brain inflammation: regulation by 1,25-dihydroxyvitamin D3. Glia. 22:1998;282-294.
21. Graeber M.B., Streit W.J., Kiefer R., Schoen S.W., Kreutzberg G.W. New expression of myelomonocytic antigens by microglia and perivascular cells following lethal motor neuron injury. J. Neuroimmunol. 27:1990;121-132.
22. Guilian D., Chen J., Ingeman J.E., George J.K., Noponen M. The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain. J. Neurosci. 12:1989;4416-4429.
23. Hibbs J.B., Taintor R.R., Vavrin Z. Macrophage cytotoxicity: role for L-arginine deaminase and iminon nitrogenoxidation to nitrite. Science. 235:1987;473-476.
24. Heneka M.T., Löschmann P.-A., Gleichmann M., Weller M., Schulz J.B., Wüllner U., Klockgether T. Induction of nitric oxide synthase and nitric oxide mediated apoptosis in neuronal PC 12 cells after stimulation with Tumor Necrosis Factor-α/lipopolysaccharide. J. Neurochem. 71:1998;88-94.
25. Heneka M.T., Schmidlin A., Wiesinger H. Induction of argininosuccinate synthetase in rat brain glial cells after striatal microinjection of immunostimulants. J. Cereb. Blood Flow Metab. 19:1999;898-907.
26. Hu J., Van Eldik L.J. S100β induces apoptotic cell death in cultured astrocytes via a nitric oxide-dependent pathway. Biochim. Biophys. Acta. 1313:1996;239-245.
27. Kitamura Y., Takahashi H., Matsuoko Y., Tooyama I., Kimura H., Nomura Y., Taniguchi T. In vivo induction of inducible nitric oxide synthase by microinjection with interferon-γ and lipopolysaccharide in rat hippocampus. Glia. 18:1996;233-243.
28. König J.F.R., Klippel R.A. The Rat Brain: A Stereotaxic Atlas of the Forebrain and Lower Parts of the Brainstem. 1963;Williams and Wilkins, Baltimore.
29. Lyons C.R., Orloff G.J., Cunningham J.M. Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line. J. Biol. Chem. 267:1992;6370-6374.
30. Minc-Golomb D., Tsarfaty I., Schwartz J.P. Expression of inducible nitric oxide synthase by neurons following exposure to endotoxin and cytokine. Br. J. Pharmacol. 112:1994;720-722.
31. Moncada S., Palmer R.M., Higgs E.A. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43:1991;109-134.
32. Montero-Menei C.N., Sindji L., Garcion E., Mege M., Couez D., Gamelin E., Darcy F. Early events of the inflammatory reaction induced in rat brain by lipopolysaccharide intracerebral injection: relative contribution of peripherial monocytes and activated microglia. Brain Res. 24:1996;55-66.
33. Murphy S., Gryzbicki P. Glial NO: normal and pathological roles. Neuroscientist. 2:1996;90-99.
34. Pitossi F., del Rey A., Kabiersch A., Besedovsky H. Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice. J. Neurosci. Res. 48:1997;287-298.
35. Schmidlin A., Wiesinger H. Argininosuccinate synthetase: localisation in astrocytes and role in the production of glial nitric oxide. Glia. 24:1998;428-436.
36. Simmons M.L., and. Murphy S. Induction of nitric oxide synthase in glial cells. J. Neurochem. 59:1992;897-905.
37. Skaper S.D., Facci L., Leon A. Inflammatory mediator stimulation of astrocytes and meningeal fibroblasts induces neuronal degeneration via the nitridergic pathway. J. Neurochem. 64:1995;266-276.
38. Smith M.A., Richey Harris P.L., Sayre L.M., Beckman J.S., Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J. Neurosci. 17:1997;2653-2657.
39. Streit W.J. Microglial cells. Ransom B., Kettenmann H. Neuroglia. 1995;85-96 Oxford University Press, New York.
40. Stuehr D.J., Marletta M.A. Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide. Proc. Natl. Acad. Sci. USA. 82:1985;7738-7742.
41. Stuehr D.J., Nathan C.F. Nitric oxide, a macrophage product responsible for cytosis and respiratory inhibition in tumor target cells. J. Exp. Med. 169:1989;1543-1555.
42. Takeuchi A., Isobe K., Miyaishi O., Sawada M., Fan Z.-H., Nakashima I., Kiuchi K. Microglial NO induces delayed neuronal death following acute injury in the striatum. Eur. J. Neurosci. 10:1998;1613-1620.
43. Ulevitch R.J., Tobias P.S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 13:1995;437-457.