The degenerative effect of a single intranigral injection of LPS on the dopaminergic system is prevented by dexamethasone, and not mimicked by rh-TNF-α IL-1β IFN-γ

Journal of Neurochemistry

Volumn 81, Issue 1, 2002, Pages 150-157

  Castano A ^a   Herrera, A J ^a   Cano, J ^a   Machado, A ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

Author keywords

Basal ganglia; Dexamethasone protection; Dopaminergic system; LPS induced neurodeganeration; Parkinson's disease; Pro inflammatory cytokines

Indexed keywords

DEXAMETHASONE; GAMMA INTERFERON; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; RECOMBINANT GAMMA INTERFERON; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; ENZYME ACTIVITY; FEMALE; GLIA CELL; INFLAMMATION; MACROPHAGE; MICROGLIA; NERVE CELL DEGENERATION; NERVE DEGENERATION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; BIOGENIC MONOAMINES; CATECHOLAMINES; CELL SURVIVAL; CORPUS STRIATUM; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DOPAMINE; FEMALE; INTERFERON TYPE II; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MICROGLIA; MICROINJECTIONS; NEURODEGENERATIVE DISEASES; NEURONS; PARKINSON DISEASE, SECONDARY; RATS; RECOMBINANT PROTEINS; SUBSTANTIA NIGRA; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE 3-MONOOXYGENASE;

ANIMALIA;

EID: 0036077851     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00799.x     Document Type: Article

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