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Volumn 9, Issue 2, 2003, Pages 562-570

Flavopiridol-related proinflammatory syndrome is associated with induction of interleukin-6

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; BASIC FIBROBLAST GROWTH FACTOR; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOKINE; FLAVOPIRIDOL; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 0037317194     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (30)

References (55)
  • 1
    • 0034722901 scopus 로고    scopus 로고
    • Small molecule modulators of cyclin-dependent kinases for cancer therapy
    • Senderowicz, A. M. Small molecule modulators of cyclin-dependent kinases for cancer therapy. Oncogene. 19: 6600-6606, 2000.
    • (2000) Oncogene , vol.19 , pp. 6600-6606
    • Senderowicz, A.M.1
  • 2
    • 0033375469 scopus 로고    scopus 로고
    • Flavopiridol: The first cyclin-dependent kinase inhibitor in human clinical trials
    • Senderowicz, A. M. Flavopiridol: the first cyclin-dependent kinase inhibitor in human clinical trials. Invest. New Drugs, 17: 313-320, 1999.
    • (1999) Invest. New Drugs , vol.17 , pp. 313-320
    • Senderowicz, A.M.1
  • 4
    • 0029665778 scopus 로고    scopus 로고
    • Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells
    • Carlson, B. A., Dubay, M. M., Sausville, E. A., Brizuela, L., and Worland. P. J. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells. Cancer Res., 56: 2973-2978, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2973-2978
    • Carlson, B.A.1    Dubay, M.M.2    Sausville, E.A.3    Brizuela, L.4    Worland, P.J.5
  • 8
    • 0033231301 scopus 로고    scopus 로고
    • Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes
    • Melillo, G., Sausville, E. A., Cloud, K., Lahusen, T., Varesio, L., and Senderowicz, A. M. Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes. Cancer Res., 59: 5433-5437, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 5433-5437
    • Melillo, G.1    Sausville, E.A.2    Cloud, K.3    Lahusen, T.4    Varesio, L.5    Senderowicz, A.M.6
  • 11
    • 0005751758 scopus 로고    scopus 로고
    • Clinical trials referral resource. Clinical trials of flavopiridol
    • Wright, J., Blamer, G. L., and Cheson, B. D. Clinical trials referral resource. Clinical trials of flavopiridol. Oncology (Huntingt), 12: 1018, 1023-1024, 1998.
    • (1998) Oncology (Huntingt) , vol.12 , Issue.1018 , pp. 1023-1024
    • Wright, J.1    Blamer, G.L.2    Cheson, B.D.3
  • 12
    • 0033955395 scopus 로고    scopus 로고
    • Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: A University of Chicago Phase II consortium study
    • Stadler, W. M., Vogelzang, N. J., Amato, R., Sosman, J., Taber, D., Liebowitz, D., and Vokes, E. E. Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: a University of Chicago Phase II consortium study. J. Clin. Oncol., 18: 371-375, 2000.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 371-375
    • Stadler, W.M.1    Vogelzang, N.J.2    Amato, R.3    Sosman, J.4    Taber, D.5    Liebowitz, D.6    Vokes, E.E.7
  • 15
    • 0033545342 scopus 로고    scopus 로고
    • Acute-phase proteins and other systemic responses to inflammation
    • Published erratum in N. Engl. J. Med., 340: 1376, 1999
    • Gabay, C., and Kushner, I, Acute-phase proteins and other systemic responses to inflammation (Published erratum in N. Engl. J. Med., 340: 1376, 1999). N. Engl. J. Med., 340: 448-454, 1999.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 448-454
    • Gabay, C.1    Kushner, I.2
  • 16
    • 0028095919 scopus 로고
    • The acute phase response
    • Baumann, H., and Gauldie, J. The acute phase response. Immunol. Today, 15: 74-80, 1994.
    • (1994) Immunol. Today , vol.15 , pp. 74-80
    • Baumann, H.1    Gauldie, J.2
  • 17
    • 0030589152 scopus 로고    scopus 로고
    • Initiation of acute phase response and synthesis of cytokines
    • Koj, A. Initiation of acute phase response and synthesis of cytokines. Biochim. Biophys. Acta, 1317: 84-94, 1996.
    • (1996) Biochim. Biophys. Acta , vol.1317 , pp. 84-94
    • Koj, A.1
  • 18
    • 0029593490 scopus 로고
    • The acute phase response and the hematopoietic system: The role of cytokines
    • Trey, J. E., and Kushner, I. The acute phase response and the hematopoietic system: the role of cytokines. Crit. Rev. Oncol. Hematol., 21: 1-18, 1995.
    • (1995) Crit. Rev. Oncol. Hematol. , vol.21 , pp. 1-18
    • Trey, J.E.1    Kushner, I.2
  • 21
    • 0033105768 scopus 로고    scopus 로고
    • Resolving conflicting signals: Cross inhibition of cytokine signaling pathways
    • Begley, C. G., and Nicola, N. A. Resolving conflicting signals: cross inhibition of cytokine signaling pathways. Blood, 93: 1443-1447, 1999.
    • (1999) Blood , vol.93 , pp. 1443-1447
    • Begley, C.G.1    Nicola, N.A.2
  • 22
    • 0032922288 scopus 로고    scopus 로고
    • Molecular regulation of cytokine gene expression during the immune response
    • Viola, J. P., and Rao, A. Molecular regulation of cytokine gene expression during the immune response. J. Clin. Immunol., 19: 98-108, 1999.
    • (1999) J. Clin. Immunol. , vol.19 , pp. 98-108
    • Viola, J.P.1    Rao, A.2
  • 23
    • 0033874108 scopus 로고    scopus 로고
    • Proinflammatory cytokines
    • Dinarello, C. A. Proinflammatory cytokines. Chest, 118: 503-508, 2000.
    • (2000) Chest , vol.118 , pp. 503-508
    • Dinarello, C.A.1
  • 25
    • 0029904810 scopus 로고    scopus 로고
    • Flavopiridol: A cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells
    • Bible, K. C., and Kaufmann, S. H. Flavopiridol: a cytotoxic flavone that induces cell death in noncycling A549 human lung carcinoma cells. Cancer Res., 56: 4856-4861, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 4856-4861
    • Bible, K.C.1    Kaufmann, S.H.2
  • 26
    • 0032533599 scopus 로고    scopus 로고
    • Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53
    • Byrd, J. C., Shinn, C., Waselenko, J. K., Fuchs, E. J., Lehman, T. A., Nguyen, P. L., Flinn, I. W., Diehl, L. F., Sausville, E., and Grever, M. R. Flavopiridol induces apoptosis in chronic lymphocytic leukemia cells via activation of caspase-3 without evidence of bcl-2 modulation or dependence on functional p53. Blood, 92: 3804-3816, 1998.
    • (1998) Blood , vol.92 , pp. 3804-3816
    • Byrd, J.C.1    Shinn, C.2    Waselenko, J.K.3    Fuchs, E.J.4    Lehman, T.A.5    Nguyen, P.L.6    Flinn, I.W.7    Diehl, L.F.8    Sausville, E.9    Grever, M.R.10
  • 29
    • 0033960068 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol
    • Li, Y., Bhuiyan, M., Alhasan, S., Senderowicz, A. M., and Sarkar, F. H. Induction of apoptosis and inhibition of c-erbB-2 in breast cancer cells by flavopiridol. Clin. Cancer Res., 6: 223-229, 2000.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 223-229
    • Li, Y.1    Bhuiyan, M.2    Alhasan, S.3    Senderowicz, A.M.4    Sarkar, F.H.5
  • 31
    • 0002504382 scopus 로고    scopus 로고
    • Preclinical and clinical development of Protein serine-threonine Kinase inhibitors
    • Senderowicz, A., Murgo, A., and Kalil, N. Preclinical and clinical development of Protein serine-threonine Kinase inhibitors. South American Journal of Cancer, 3: 95-112, 2000.
    • (2000) South American Journal of Cancer , vol.3 , pp. 95-112
    • Senderowicz, A.1    Murgo, A.2    Kalil, N.3
  • 33
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • Taga, T., and Kishimoto, T. Gp130 and the interleukin-6 family of cytokines. Annu. Rev. Immunol., 15: 797-819, 1997.
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 34
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira, S., Taga, T., and Kishimoto, T. Interleukin-6 in biology and medicine. Adv. Immunol., 54: 1-78, 1993.
    • (1993) Adv. Immunol. , vol.54 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 36
    • 0029147155 scopus 로고
    • Toxicity and efficacy of escalating dosages of recombinant human interleukin-6 after chemotherapy in patients with breast cancer or non-small-cell lung cancer
    • Veldhuis, G. J., Willemse, P. H., Sleijfer, D. T., van der Graaf, W. T., Groen, H. J., Limburg, P. C., Mulder, N. H., and de Vries, E. G. Toxicity and efficacy of escalating dosages of recombinant human interleukin-6 after chemotherapy in patients with breast cancer or non-small-cell lung cancer, J. Clin. Oncol., 13: 2585-2593, 1995.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 2585-2593
    • Veldhuis, G.J.1    Willemse, P.H.2    Sleijfer, D.T.3    Van der Graaf, W.T.4    Groen, H.J.5    Limburg, P.C.6    Mulder, N.H.7    De Vries, E.G.8
  • 39
    • 0033386539 scopus 로고    scopus 로고
    • Protein kinase C targeting in antineo-plastic treatment strategies
    • Jarvis, W. D., and Grant, S. Protein kinase C targeting in antineo-plastic treatment strategies. Investig. New Drugs, 17: 227-240, 1999.
    • (1999) Investig. New Drugs , vol.17 , pp. 227-240
    • Jarvis, W.D.1    Grant, S.2
  • 43
    • 0029075385 scopus 로고
    • A phase I trial of recombinant human interleukin-6 in patients with myelodysplastic syndromes and thrombocytopenia
    • Gordon, M. S., Nemunaitis, J., Hoffman, R., Paquette, R. L., Rosenfeld, C., Manfreda, S., Isaacs, R., and Nimer, S. D. A phase I trial of recombinant human interleukin-6 in patients with myelodysplastic syndromes and thrombocytopenia. Blood, 85: 3066-3076, 1995.
    • (1995) Blood , vol.85 , pp. 3066-3076
    • Gordon, M.S.1    Nemunaitis, J.2    Hoffman, R.3    Paquette, R.L.4    Rosenfeld, C.5    Manfreda, S.6    Isaacs, R.7    Nimer, S.D.8
  • 44
    • 0031183766 scopus 로고    scopus 로고
    • The role of nuclear factor-kappa B in cytokine gene regulation
    • Blackwell, T. S., and Christman, J. W. The role of nuclear factor-kappa B in cytokine gene regulation. Am. J. Respir. Cell Mol. Biol., 17: 3-9, 1997.
    • (1997) Am. J. Respir. Cell Mol. Biol. , vol.17 , pp. 3-9
    • Blackwell, T.S.1    Christman, J.W.2
  • 45
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin, A. S., Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu. Rev. Immunol., 14: 649-683, 1996.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin A.S., Jr.1
  • 46
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins, N. D., Felzien, L. K., Betts, J. C., Leung, K., Beach, D. H., and Nabel, G. J. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science, 275: 523-527, 1997.
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 47
    • 0030198344 scopus 로고    scopus 로고
    • Protein kinase cascades activated by stress and inflammatory cytokines
    • Kyriakis, J. M., and Avruch, J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays, 18: 567-577, 1996.
    • (1996) Bioessays , vol.18 , pp. 567-577
    • Kyriakis, J.M.1    Avruch, J.2
  • 48
    • 0033616588 scopus 로고    scopus 로고
    • Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression
    • Wysk, M., Yang, D. D., Lu, H. T., Flavell, R. A., and Davis, R. J. Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression. Proc. Natl. Acad. Sci. USA, 96: 3763-3768, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3763-3768
    • Wysk, M.1    Yang, D.D.2    Lu, H.T.3    Flavell, R.A.4    Davis, R.J.5
  • 51
    • 2842605597 scopus 로고
    • Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-beta 2
    • Chen, L., Mory, Y., Zilberstein, A., and Revel, M. Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-beta 2. Proc. Natl. Acad. Sci. USA, 85: 8037-8041, 1988.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8037-8041
    • Chen, L.1    Mory, Y.2    Zilberstein, A.3    Revel, M.4
  • 52
    • 0025321245 scopus 로고
    • Antitumor activity of recombinant interleukin 6 in mice
    • Mule, J. J., McIntosh, J. K., Jablons, D. M., and Rosenberg, S. A. Antitumor activity of recombinant interleukin 6 in mice. J. Exp. Med., 171: 629-636, 1990.
    • (1990) J. Exp. Med. , vol.171 , pp. 629-636
    • Mule, J.J.1    McIntosh, J.K.2    Jablons, D.M.3    Rosenberg, S.A.4
  • 53
    • 0026760711 scopus 로고
    • Interleukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells
    • Ullmann, C. D., Schlom, J., and Greiner, J. W. Interleukin-6 increases carcinoembryonic antigen and histocompatibility leukocyte antigen expression on the surface of human colorectal carcinoma cells. J. Immunother., 12: 231-241, 1992.
    • (1992) J. Immunother. , vol.12 , pp. 231-241
    • Ullmann, C.D.1    Schlom, J.2    Greiner, J.W.3
  • 54
    • 0035045564 scopus 로고    scopus 로고
    • Multiple myeloma. Advances in disease biology: Therapeutic implications
    • Anderson, K. C. Multiple myeloma. Advances in disease biology: therapeutic implications. Semin. Hematol., 38: 6-10, 2001.
    • (2001) Semin. Hematol. , vol.38 , pp. 6-10
    • Anderson, K.C.1
  • 55
    • 0034123859 scopus 로고    scopus 로고
    • Malignancy: Identification of predictors of disease status and progression in patients with myeloma (MM)
    • Salem, M., Elbaz, O., Zahran, M., Elbaz, A., Elgamal, S., Eteba, S., and Mahmoud, L. A. Malignancy: identification of predictors of disease status and progression in patients with myeloma (MM). Hematology, 5: 41-45, 2000.
    • (2000) Hematology , vol.5 , pp. 41-45
    • Salem, M.1    Elbaz, O.2    Zahran, M.3    Elbaz, A.4    Elgamal, S.5    Eteba, S.6    Mahmoud, L.A.7


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