Cell and molecular biology of myoblast fusion

International Review of Cytology

Volumn 225, Issue , 2003, Pages 33-89

  Abmayr, Susan M ^a   Balagopalan, Lakshmi ^a   Galletta, Brian J ^a   Hong, Sue Jean ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Adhesion; Drosophila; Fusion; Myoblast fusion; Myogenesis; Signaling; Skeletal muscle

Indexed keywords

CADHERIN; CALPAIN; CALPASTATIN; CELL ADHESION MOLECULE; CELL SURFACE PROTEIN; FUSION ASSOCIATED MEMBRANE PROTEIN; HYBRID PROTEIN; MEMBRANE LIPID; MEMBRANE PROTEIN; MYOBLAST SURFACE PROTEIN; NERVE CELL ADHESION MOLECULE; PHOSPHOLIPID; PROSTAGLANDIN; PROTEIN KINASE C; SCLEROPROTEIN; UNCLASSIFIED DRUG;

CELL ADHESION; CELL DIFFERENTIATION; CELL FUSION; CELL ULTRASTRUCTURE; CYTOSKELETON; DROSOPHILA; EMBRYO DEVELOPMENT; GENE; GENE LOCUS; GENETICS; HUMAN; MAMMAL; MESODERM; MUSCLE CELL; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; REVIEW; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SYNCYTIUM; TISSUE CULTURE; VERTEBRATE;

MAMMALIA; VERTEBRATA;

EID: 0037262161     PISSN: 00747696     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0074-7696(05)25002-7     Document Type: Review

References (259)

1. Adamo, S., Caporale, C., Nervi, C., Ceci, R., and Molinaro, M. (1989). Activity and regulation of calcium-, phospholipid-dependent protein kinase in differentiating chick myogenic cells. J. Cell Biol. 108, 153-158.
2. Andres, V., and Walsh, K. (1996). Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis. J. Cell Biol. 132, 657-666.
3. Antin, P. B., Forry-Schaudies, S., Friedman, T. M., Tapscott, S. J., and Holtzer, H. (1981). Taxol induces postmitotic myoblasts to assemble interdigitating microtubule-myosin arrays that exclude actin filaments. J. Cell Biol. 90, 300-308.
4. Artero, R. D., Castanon, I., and Baylies, M. K. (2001). The immunoglobulin-like protein Hibris functions as a dose-dependent regulator of myoblast fusion and is differentially controlled by Ras and Notch signaling. Development 128, 4251-4264.
5. Bahjaoui-Bouhaddi, M., Padilla, F., Nicolet, M., Cifuentes-Diaz, C., Fellmann, D., and Mege, R. M. (1997). Localized deposition of M-cadherin in the glomeruli of the granular layer during the postnatal development of mouse cerebellum. J. Comp. Neurol. 378, 180-195.
6. Balagopalan, L., Keller, C. A., and Abmayr, S. M. (2001). Loss-of-function mutations reveal that the Drosophila nautilus gene is not essential for embryonic myogenesis or viability. Dev. Biol. 231, 374-382.
7. Balcerzak, D., Poussard, S., Brustis, J. J., Elamrani, N., Soriano, M., Cottin, P., and Ducastaing, A. (1995). An antisense oligodeoxyribonucleotide to m-calpain mRNA inhibits myoblast fusion. J. Cell Sci. 108, 2077-2082.
8. Balcerzak, D., Cottin, P., Poussard, S., Cucuron, A., Brustis, J. J., and Ducastaing, A. (1998). Calpastatin-modulation of m-calpain activity is required for myoblast fusion. Eur. J. Cell Biol. 75, 247-253.
9. Barnoy, S., Glaser, T., and Kosower, N. S. (1998). The calpain-calpastatin system and protein degradation in fusing myoblasts. Biochim. Biophys. Acta 1402, 52-60.
10. Bar-Sagi, D., and Prives, J. (1983). Trifluoperazine, a calmodulin antagonist, inhibits muscle cell fusion. J. Cell Biol. 97, 1375-1380.
11. Bashaw, G. J., and Goodman, C. S. (1999). Chimeric axon guidance receptors: The cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion. Cell 97, 917-926.
12. Bashaw, G. J., Kidd, T., Murray, D., Pawson, T., and Goodman, C. S. (2000). Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the Roundabout receptor. Cell 101, 703-715.
13. Bate, M. (1990). The embryonic development of larval muscles in Drosophila. Development 110, 791-804.
14. Bate, M. (1993). The mesoderm and its derivatives. In "The Development of Drosophila melanogaster" (M. Bate and A. Martinez Arias, Eds.), pp. 1013-1090. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
15. Bate, M., and Rushton, E. (1993). Myogenesis and muscle patterning in Drosophila. C. R. Acad. Sci. Paris 316, 1055-1061.
16. Baylies, M. K., and Bate, M. (1996). twist: A myogenic switch in Drosophila. Science 272, 1481-1484.
17. Baylies, M. K., Bate, M., and Ruiz Gomez, M. (1998). Myogenesis: A view from Drosophila. Cell 93, 921-927.
18. 2+ signaling during terminal differentiation (fusion) of human myoblasts. Proc. Natl. Acad. Sci. USA 97, 7627-7632.
19. Bischoff, R. (1978). Myoblast Fusion. In "Membrane Fusion" (G. Poste and G. L. Nicolson, Eds.), pp. 127-179. North-Holland Publishing Company, New York.
20. Bischoff, R. (1994). The satellite cell and muscle regeneration. In "Myogenesis" (A. G. Engel and C. Franszini-Armstrong, Eds.), pp. 97-118. McGraw-Hill, New York.
21. Black, B. L., and Olson, E. N. (1998). Transcriptional control of muscle development by myocyte enhancer factor-2 (MEF2) proteins. Annu. Rev. Cell Dev. Biol. 14, 167-196.
22. Borkowski, O. M., Brown, N. H., and Bate, M. (1995). Anterior-posterior subdivision and the diversification of the mesoderm in Drosophila. Development 121, 4183-4193.
23. Bornemann, A., and Schmalbruch, H. (1994). Immunocytochemistry of M-cadherin in mature and regenerating rat muscle. Anat. Rec. 239, 119-125.
24. Bour, B. A., O'Brien, M. A., Lockwood, W. L., Goldstein, E. S., Bodmer, R., Taghert, P. H., Abmayr, S. M., and Nguyen, H. T. (1995). Drosophila MEF2, a transcription factor that is essential for myogenesis. Genes Dev. 9, 730-741.
25. Bour, B. A., Chakravarti, M., West, J. M., and Abmayr, S. M. (2000). Drosophila SNS, a member of the immunoglobulin superfamily that is essential for myoblast fusion. Genes Dev. 14, 1498-1511.
26. Bradshaw, J. P., Darkes, M. J., Harroun, T. A., Katsaras, J., and Epand, R. M. (2000). Oblique membrane insertion of viral fusion peptide probed by neutron diffraction. Biochemistry 39, 6581-6585.
27. Brand-Saberi, B., and Christ, B. (1999). Genetic and epigenetic control of muscle development in vertebrates. Cell Tissue Res. 296, 199-212.
28. Buckingham, M. (2001). Skeletal muscle formation in vertebrates. Curr. Opin. Genet. Dev. 11, 440-448.
29. Bullough, P. A., Hughson, F. M., Skehel, J. J., and Wiley, D. C. (1994). Structure of influenza haemagglutinin at the pH of membrane fusion. Nature 371, 37-43.
30. Bunch, T. A., and Brower, D. L. (1993). Drosophila cell adhesion molecules. Curr. Top. Dev. Biol. 28, 81-123.
31. Capiati, D. A., Tellez-Inon, M. T., and Boland, R. L. (1999). Participation of protein kinase C alpha in 1,25-dihydroxy-vitamin D3 regulation of chick myoblast proliferation and differentiation. Mol. Cell. Endocrinol. 153, 39-45.
32. Carmena, A., Bate, M., and Jimenez, F. (1995). lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis. Genes Dev. 9, 2373-2383.
33. Carmena, A., Gisselbrecht, S., Harrison, J., Jimenez, F., and Michelson, A. M. (1998). Combinatorial signaling codes for progressive determination of cell fates in the Drosophila embryonic mesoderm. Genes Dev. 12, 3910-3922.
34. Carr, C. M., and Kim, P. S. (1993). A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell 73, 823-832.
35. Charlton, C. A., Mohler, W. A., Radice, G. L., Hynes, R. O., and Blau, H. M. (1997). Fusion competance of myoblasts rendered genetically null for N-cadherin in culture. J. Cell Biol. 138, 331-336.
36. Charlton, C. A., Mohler, W. A., and Blau, H. M. (2000). Neural cell adhesion molecule (NCAM) and myoblast fusion. Dev. Biol. 221, 112-119.
37. Chen, E. H., and Olson, E. N. (2001). Antisocial, an intracellular adaptor protein, is required for myoblast fusion in Drosophila. Dev. Cell 1, 705-715.
38. Constantin, B., Cognard, C., and Raymond, G. (1996). Myoblast fusion requires cytosolic calcium elevation but not activation of voltage-dependent calcium channels. Cell Calcium 19, 365-374.
39. Cooper, E. (2001). A new role for ion channels in myoblast fusion. J. Cell Biol. 153, F9-12.
40. Couch, C. B., and Strittmatter, W. J. (1983). Rat myoblast fusion requires metalloendoprotease activity. Cell 32, 257-265.
41. Couch, C. B., and Strittmatter, W. J. (1984). Specific blockers of myoblast fusion inhibit a soluble and not the membrane-associated metalloendoprotease in myoblasts. J. Biol. Chem. 259, 5396-5399.
42. Cremer, H., Lange, R., Christoph, A., Plomann, M., Vopper, G., Roes, J., Brown, R., Baldwin, S., Kraemer, P., Scheff, S., Barthels, D., Rajewsky, K., and Willr, W. (1994). Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning. Nature 367, 455-459.
43. Cunningham, B. A., Hoffman, S., Rutishauser, U., Hemperly, J. J., and Edelman, G. M. (1983). Molecular topography of the neural cell adhesion molecule N-CAM: Surface orientation and location of sialic acid-rich and binding regions. Proc. Natl. Acad. Sci. USA 80, 3116-3120.
44. Cunningham, B. A., Hemperley, J. J., Murray, B. A., Prediger, E. A., Brackenbury, R., and Edelman, G. M. (1987). Neural cell adhesion molecule: Structure, immunoglobulin-like domains, cell surface modulation and alternative splicing. Science 236, 799-806.
45. David, J. D., and Higginbotham, C. A. (1981). Fusion of chick embryo skeletal myoblasts: Interactions of prostaglandin E1, adenosine 3′:5′ monophosphate, and calcium influx. Dev. Biol. 82, 308-316.
46. David, J. D., See, W. M., and Higginbotham, C. A. (1981). Fusion of chick embryo skeletal myoblasts: Role of calcium influx preceding membrane union. Dev. Biol. 82, 297-307.
47. David, J. D., Faser, C. R., and Perrot, G. P. (1990). Role of protein kinase C in chick embryo skeletal myoblast fusion. Dev. Biol. 139, 89-99.
48. Davis, D. B., Delmonte, A. J., Ly, C. T., and McNally, E. M. (2000). Myoferlin, a candidate gene and potential modifier of muscular dystrophy. Hum. Mol. Genet. 9, 217-226.
49. Davis, D. B., Doherty, K. R., Delmonte, A. J., and McNally, E. M. (2002). Calcium-sensitive phospholipid binding properties of normal and mutant ferlin C2 domains. J. Biol. Chem. 277, 22883-22888.
50. Den, H., Malinzak, D. A., Keating, H. J., and Rosenberg, A. (1975). Influence of concanavalin A, wheat germ agglutinin, and soybean agglutinin on the fusion of myoblasts in vitro. J. Cell Biol. 67, 826-834.
51. Dickson, G., Gower, H. J., Barton, C. H., Prentice, H. M., Elsom, V. L., Moore, S. E., Cox, R. D., Quinn, C.,Putt, W., and Walsh, F. S. (1987). Human muscle neural cell adhesion molecule (N-CAM): Identification of a muscle-specific sequence in the extracellular domain. Cell 50, 1119-1130.
52. Dickson, G., Peck, D., Moore, S. E., Barton, C. H., and Walsh, F. S. (1990). Enhanced myogenesis in NCAM-transfected mouse myoblasts. Nature 344, 348-351.
53. Doberstein, S. K., Fetter, R. D., Mehta, A. Y., and Goodman, C. S. (1997). Genetic analysis of myoblast fusion: blown fuse is required for progression beyond the prefusion complex. J. Cell Biol. 136, 1249-1261.
54. Donalies, M., Cramer, M., Ringwald, M., and Starzinski-Powitz, A. (1991). Expression of M-cadherin, a member of the cadherin multigene family, correlates with differentiation of skeletal muscle cells. Proc. Natl. Acad. Sci. USA 88, 8024-8028.
55. Dourdin, N., Brustis, J. J., Balcerzak, D., Elamrani, N., Poussard, S., Cottin, P., and Ducastaing, A. (1997). Myoblast fusion requires fibronectin degradation by exteriorized m-calpain. Exp. Cell Res. 235, 385-394.
56. Dourdin, N., Balcerzak, D., Brustis, J. J., Poussard, S., Cottin, P., and Ducastaing, A. (1999). Potential m-calpain substrates during myoblast fusion. Exp. Cell Res. 246, 433-442.
57. Draeger, A., Weeds, A. G., and Fitzsimons, R. B. (1987). Primary, secondary and tertiary myotubes in developing skeletal muscle: A new approach to the analysis of human myogenesis. J. Neurol. Sci. 81, 19-43.
58. Drysdale, R., Rushton, E., and Bate, M. (1993). Genes required for embryonic muscle development in Drosophila melanogaster. Roux's Arch. Dev. Biol. 202, 276-295.
59. Duan, H., Skeath, J. B., and Nguyen, H. T. (2001). Drosophila Lame duck, a novel member of the Gli superfamily, acts as a key regulator of myogenesis by controlling fusion-competent myoblast development. Development 128, 4489-4500.
60. Duchek, P., Somogyi, K., Jekely, G., Beccari, S., and Rorth, P. (2001). Guidance of cell migration by the Drosophila PDGF/VEGF receptor. Cell 107, 17-26.
61. Duxson, M. J., Usson, Y., and Harris, A. J. (1989). The origin of secondary myotubes in mammalian skeletal muscles: Ultrastructural studies. Development 107, 743-750.
62. Dworak, H. A., and Sink, H. (2002). Myoblast fusion in Drosophila. Bioessays 24, 591-601.
63. Dworak, H. A., Charles, M. A., Pellerano, L. B., and Sink, H. (2001). Characterization of Drosophila hibris, a gene related to human nephrin. Development 128, 4265-4276.
64. Ebisui, C., Tsujinaka, T., Kido, Y., Iijima, S., Yano, M., Shibata, H., Tanaka, T., and Mori, T. (1994). Role of intracellular proteases in differentiation of L6 myoblast cells. Biochem. Mol. Biol. Int. 32, 515-521.
65. Elamrani, N., Brustis, J. J., Dourdin, N., Balcerzak, D., Poussard, S., Cottin, P., and Ducastaing, A. (1995). Desmin degradation and Ca(2+)-dependent proteolysis during myoblast fusion. Biol. Cell 85, 177-183.
66. Ellis, R. E., Jacobson, D. M., and Horvitz, H. R. (1991). Genes required for the engulfment of cell corpses during programmed cell death in Caenorhabditis elegans. Genetics 129, 79-94.
67. Engel, L. C., Egar, M. W., and Przybylski, R. J. (1985). Morphological characterization of actively fusing L6 myoblasts. Eur. J. Cell Biol. 39, 360-365.
68. Entwistle, A., Curtis, D. H., and Zalin, R. J. (1986). Myoblast fusion is regulated by a prostanoid of the one series independently of a rise in cyclic AMP. J. Cell Biol. 103, 857-866.
69. Entwistle, A., Zalin, R. J., Bevan, S., and Warner, A. E. (1988). The control of chick myoblast fusion by ion channels operated by prostaglandins and acetylcholine. J. Cell Biol. 106, 1693-1702.
70. Epand, R. M. (1998). Lipid polymorphism and protein-lipid interactions. Biochim. Biophys. Acta 1376, 353-368.
71. Epand, R. M. (2000). Membrane fusion. Biosci. Rep. 20, 435-441.
72. Epand, R. M., Maekawa, S., Yip, C. M., and Epand, R. F. (2001). Protein-induced formation of cholesterol-rich domains. Biochemistry 40, 10514-10521.
73. Erickson, M. R. S., Galletta, B. J., and Abmayr, S. M. (1997). Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure and cytoskeletal organization. J. Cell Biol. 138, 589-603.
74. Fadok, V. A., Bratton, D. L., Frasch, S. C., Warner, M. L., and Henson, P. M. (1998). The role of phosphatidylserine in recognition of apoptotic cells by phagocytes. Cell Death Differ. 5, 551-562.
75. Fadok, V. A., Bratton, D. L., and Henson, P. M. (2001). Phagocyte receptors for apoptotic cells: Recognition, uptake, and consequences. J. Clin. Invest. 108, 957-962.
76. Farzaneh, F., Entwistle, A., and Zalin, R. J. (1989). Protein kinase C mediates the hormonally regulated plasma membrane fusion of avian embryonic skeletal muscle. Exp. Cell Res. 181, 298-304.
77. Fazeli, S., Wells, D. J., Hobbs, C., and Walsh, F. S. (1996). Altered secondary myogenesis in transgenic animals expressing the neural cell adhesion molecule under the control of a skeletal muscle alphaactin promoter. J. Cell Biol. 135, 241-251.
78. Feller, S. M., Knudsen, B., and Hanafusa, H. (1995). Cellular proteins binding to the first Src homology 3 (SH3) domain of the proto-oncogene product c-Crk indicate Crk-specific signaling pathways. Oncogene 10, 1465-1473.
79. Feller, S. M., Posern, G., Voss, J., Kardinal, C., Sakkab, D., Zheng, J., and Knudsen, B. S. (1998). Physiological signals and oncogenesis mediated through Crk family adapter proteins. J. Cell Physiol. 177, 535-552.
80. Frasch, M. (1999). Controls in patterning and diversification of somatic muscles during Drosophila embryogenesis. Curr. Opin. Genet. Dev. 9, 522-529.
81. Friedlander, M., and Fischman, D. A. (1977). Surface antigens of the embryonic chick myoblast: Expression on freshly trypsinized cells. J. Supramol. Struct. 7, 323-338.
82. Friedlander, M., and Fischman, D. A. (1979). Immunological studies of the embryonic muscle cell surface. Antiserum to the prefusion myoblast. J. Cell Biol. 81, 193-214.
83. Fulton, A. B., Prives, J., Farmer, S. R., and Penman, S. (1981). Developmental reorganization of the skeletal framework and its surface lamina in fusing muscle cells. J. Cell Biol. 91, 103-112.
84. Furlong, E. E., Andersen, E. C., Null, B., White, K. P., and Scott, M. P. (2001). Patterns of gene expression during Drosophila mesoderm development. Science 293, 1629-1633.
85. Galletta, B. J., Niu, X.-P., Erickson, M. R. S., and Abmayr, S. M. (1999). Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC. Gene 228, 243-252.
86. Galliano, M. F., Huet, C., Frygelius, J., Polgren, A., Wewer, U. M., and Engvall, E. (2000). Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha-actinin-2, is required for myoblast fusion. J. Biol. Chem. 275, 13933-13939.
87. Geiger, B., and Ayalon, O. (1992). Cadherins. Annu. Rev. Cell Biol. 8, 307-332.
88. Gennarini, G., Rougon, G., Deagostini-Bazin, H., Hirn, M., and Goridis, C. (1984). Studies on the transmembrane disposition of the neural cell adhesion molecule N-CAM. A monoclonal antibody recognizing a cytoplasmic domain and evidence for the presence of phosphoserine residues. Eur. J. Biochem. 142, 57-64.
89. Gibralter, D., and Turner, D. C. (1985). Dual adhesion systems of chick myoblasts. Dev. Biol. 112, 292-307.
90. Gilfix, B. M., and Sanwal, B. D. (1980). Inhibition of myoblast fusion by tunicamycin and pantomycin. Biochem. Biophys. Res. Commun. 96, 1184-1191.
91. Gorza, L., and Vitadello, M. (2000). Reduced amount of the glucose-regulated protein GRP94 in skeletal myoblasts results in loss of fusion competence. FASEB J. 14, 461-475.
92. Gregorio, C. C., Granzier, H., Sorimachi, H., and Labeit, S. (1999). Muscle assembly: A titanic achievement? Curr. Opin. Cell Biol. 11, 18-25.
93. Hakeda-Suzuki, S., Ng, J., Tzu, J., Dietzl, G., Sun, Y., Harms, M., Nardine, T., Luo, L., and Dickson, B. J. (2002). Rac function and regulation during Drosophila development. Nature 416, 438-442.
94. Hall, A. (1998). Rho GTPases and the actin cytoskeleton. Science 279, 509-514.
95. Harden, N., Loh, H. Y., Chia, W., and Lim, L. (1995). A dominant inhibitory version of the small GTP-binding Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila. Development 121, 903-914.
96. Harris, H. A., Murrills, R. J., and Komm, B. S. (1997). Expression of meltrin-alpha mRNA is not restricted to fusagenic cells. J. Cell. Biochem. 67, 136-142.
97. Hasegawa, H., Kiyokawa, E., Tanaka, S., Nagashima, K., Gotoh, N., Shibuya, M., Kurata, T., and Matsuda, M. (1996). DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane. Mol. Cell. Biol. 16, 1770-1776.
98. Henson, P. M., Bratton, D. L., and Fadok, V. A. (2001a). Apoptotic cell removal. Curr. Biol. 11, R795-805.
99. Henson, P. M., Bratton, D. L., and Fadok, V. A. (2001b). The phosphatidylserine receptor: A crucial molecular switch? Nat. Rev. Mol. Cell Biol. 2, 627-633.
100. Herman, B. A., and Fernandez, S. M. (1978). Changes in membrane dynamics associated with myogenic cell fusion. J. Cell. Physiol. 94, 253-264.
101. Herman, B. A., and Fernandez, S. M. (1982). Dynamics and topographical distribution of surface glycoproteins during myoblast fusion: A resonance energy transfer study. Biochemistry 21, 3275-3283.
102. Hernandez, L. D., Hoffman, L. R., Wolfsberg, T. G., and White, J. M. (1996). Virus-cell and cell-cell fusion. Annu. Rev. Cell Dev. Biol. 12, 627-661.
103. Hoffman, S., and Edelman, G. M. (1983). Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule. Proc. Natl. Acad. Sci. USA 80, 5762-5766.
104. Hoffmann, P. R., deCathelineau, A. M., Ogden, C. A., Leverrier, Y., Bratton, D. L., Daleke, D. L., Ridley, A. J., Fadok, V. A., and Henson, P. M. (2001). Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J. Cell Biol. 155, 649-659.
105. Hollnagel, A., Grund, C., Franke, W. W., and Arnold, H. H. (2002). The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. Mol. Cell. Biol. 22, 4760-4770.
106. Holtzer, H., Croop, J., Dienstman, S., Ishikawa, H., and Somlyo, A. P. (1975). Effects of cytochaslasin B and colcemide on myogenic cultures. Proc. Natl. Acad. Sci. USA 72, 513-517.
107. Hortsch, M., and Goodman, C. S. (1991). Cell and substrate adhesion molecules in Drosophila. Annu. Rev. Cell Biol. 7, 505-557.
108. Horwitz, A., Wight, A., Ludwig, P., and Cornell, R. (1978). Interrelated lipid alterations and their influence on the proliferation and fusion of cultured myogenic cells. J. Cell Biol. 77, 334-357.
109. Horwitz, A., Wight, A., and Knudsen, K. (1979). A role for lipid in myoblast fusion. Biochem. Biophys. Res. Commun. 86.
110. Kalderon, N. (1980). Muscle cell fusion. In "Membrane-Membrane Interactions" (N. B. Gilula Ed.), pp. 99-118. Raven Press, New York.
111. Kalderon, N., and Gilula, N. B. (1979). Membrane events involved in myoblast fusion. J. Cell Biol. 81, 411-425.
112. Kania, A., Han, P. L., Kim, Y. T., and Bellen, H. (1993). Neuromusculin, a Drosophila gene expressed in peripheral neuronal precursors and muscles, encodes a cell adhesion molecule. Neuron 11, 673-687.
113. Kaufman, S. J., Foster, R. F., Haye, K. R., and Faiman, L. E. (1985). Expression of a developmentally regulated antigen on the surface of skeletal and cardiac muscle cells. J. Cell Biol. 100, 1977-1987.
114. Keller, C. A., Grill, M. A., and Abmayr, S. M. (1998). A role for nautilus in the differentiation of muscle precursors. Dev. Biol. 202, 157-171.
115. Kelly, K. K., Meadows, S. M., and Cripps, R. M. (2002). Drosophila MEF2 is a direct regulator of Actin57B transcription in cardiac, skeletal, and visceral muscle lineages. Mech. Dev. 110, 39-50,
116. Kent, C., Schimmel, S. D., and Vagelos, P. R. (1974). Lipid composition of plasma membranes from developing chick muscle cells in culture. Biochim, Biophys. Acta 360, 312-321.
117. Kestila, M., Lenkkeri, U., Mannikko, M., Lamerdin, J., McCready, P., Putaala, H., Ruotsalainen, V., Morita, T., Nissinen, M., Peltonen, L., Holmberg, C., Olsen, A., and Tryggvason, K. (1998). Positionally cloned gene for a novel glomerular protein - Nephrin - is mutated in congenital nephrotic syndrome. Mol. Cell 1, 572-582.
118. Kim, S. S., Kim, J. H., Kim, H. S., Park, D. E., and Chung, C. H. (2000). Involvement of the theta-type protein kinase C in translocation of myristoylated alanine-rich C kinase substrate (MARCKS) during myogenesis of chick embryonic myoblasts. Biochem. J. 347(pt. 1), 139-146.
119. Kinnunen, P. K., and Holopainen, J. M. (2000). Mechanisms of initiation of membrane fusion: Role of lipids. Biosci. Rep. 20, 465-482.
120. Kiyokawa, E., Hashimoto, Y., Kobayashi, S., Sugimura, H., Kurata, T., and Matsuda, M. (1998). Activation of Racl by a Crk SH3-binding protein, DOCK180. Genes Dev. 12, 3331-3336.
121. Knudsen, K. A. (1985). The calcium-dependent myoblast adhesion that precedes fusion is dependent on glycoproteins. J. Cell Biol. 101, 891-897.
122. Knudsen, K. A. (1990). Cell adhesion molecules in myogenesis. Curr. Opin. Cell Biol. 2, 902-906.
123. Knudsen, K. A. (1992). Fusion of myoblasts. In "Membrane Fusion" (J. Wilschut and D. Hoekstra, Eds.), pp. 601-626. Marcel Dekker, Inc., New York.
124. Knudsen, K. A., and Horwitz, A. F. (1977). Tandem events in myoblast fusion. Dev. Biol. 58, 328-338.
125. Knudsen, K. A., and Horwitz, A. F. (1978). Differential inhibition of myoblast fusion. Dev. Biol. 66, 294-307.
126. Knudsen, K. A., Smith, L., and McElwee, S. (1989). Involvement of cell surface phosphatidylinositol-anchored glycoproteins in cell-cell adhesion of chick embryo myoblasts. J. Cell Biol. 109, 1779-1786.
127. Knudsen, K. A., McElwee, S. A., and Myers, L. (1990a). A role for the neural cell adhesion molecule, NCAM, in myoblast interaction during myogenesis. Dev. Biol. 138, 159-168.
128. 2+-dependent adhesion molecule, N-Cadherin, in myoblast interaction during myogenesis. Exp. Cell Res. 188, 175-184.
129. Kolodziej, P. A., Timpe, L. C., Mitchell, K. J., Fried, S. R., Goodman, C. S., Jan, L. Y., and Jan, Y. N. (1996). frazzled encodes a Drosophila member of the DCC immunoglobulin subfamily and is required for CNS and motor axon guidance. Cell 87, 197-204.
130. Kuch, C., Winnekendonk, D., Butz, S., Unvericht, U., Kemler, R., and Starzinski-Powitz, A. (1997). M-cadherin-mediated cell adhesion and complex formation with the catenins in myogenic mouse cells. Exp. Cell Res. 232, 331-338.
131. Kurisaki, T., Masuda, A., Osumi, N., Nabeshima, Y., and Fujisawa-Sehara, A. (1998). Spatially- and temporally-restricted expression of meltrin alpha (ADAM-12) and beta (ADAM-19) in mouse embryo. Mech. Dev. 73, 211-215.
132. Kwak, K. B., Chung, S. S., Kim, O. M., Kang, M. S., Ha, D. B., and Chung, C. H. (1993). Increase in the level of m-calpain correlates with the elevated cleavage of filamin during myogenic differentiation of embryonic muscle cells. Biochim. Biophys. Acta 1175, 243-249.
133. Lee, H. U., and Kaufman, S. J. (1981). Use of monoclonal antibodies in the analysis of myoblast development. Dev. Biol. 81, 81-95.
134. Lenkkeri, U., Mannikko, M., McCready, P., Lamerdin, J., Gribouval, O., Niaudet, P., Antignac, C., Kashtan, C. E., Holmberg, C., Olsen, A., Kestila, M., and Tryggvason, K. (1999). Structure of the gene for congenital nephrotic syndrome of the Finnish type (NPHS1) and characterization of mutations. Am. J. Hum. Genet. 64, 51-61.
135. Leptin, M. (1991). twist and snail as positive and negative regulators during Drosophila mesoderm development. Genes Dev. 5, 1568-1576.
136. Li, H., Choudhary, S. K., Milner, D. J., Munir, M. I., Kuisk, I. R., and Capetanaki, Y. (1994). Inhibition of desmin expression blocks myoblast fusion and interferes with the myogenic regulators MyoD and myogenin. J. Cell Biol. 124, 827-841.
137. Lilly, B., Galewsky, S., Firulli, A. B., Schulz, R. A., and Olson, E. N. (1994). D-MEF2: A MADS box transcription factor expressed in differentiating mesoderm and muscle cell lineages during Drosophila embryogenesis. Proc. Natl. Acad. Sci. USA 91, 5662-5666.
138. Lin, M. H., Bour, B. A., Abmayr, S. M., and Storti, R. V. (1997). Ectopic expression of MEF2 in the epidermis induces epidermal expression of muscle genes and abnormal muscle development in Drosophila. Dev. Biol. 182, 240-255.
139. Lin, Q., Schwarz, J., Bucana, C., and Olson, E. N. (1997). Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. Science 276, 1404-1407.
140. Lindau, M., and Almers, W. (1995). Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion. Curr. Opin. Cell Biol. 7, 509-517.
141. Lipton, B. H., and Konigsberg, I. R. (1972). A fine-structural analysis of the fusion of myogenic cells. J. Cell Biol. 53, 348-364.
142. Lognonne, J. L., and Wahrmann, J. P. (1988). A cell surface phosphoprotein of 48 kDa specific for myoblast fusion. Cell Differ. 22, 245-258.
143. Luo, L., Liao, Y. J., Jan, L. Y., and Jan, Y. N. (1994). Distinct morphogenetic functions of similar small GTPases: Drosophila Drac-is involved in axonal outgrowth and myoblast fusion. Genes Dev. 8, 1787-1802.
144. Lyles, J. M., Linnemann, D., and Bock, E. (1984). Biosynthesis of the D2-cell adhesion molecule: Post-translational modifications, intracellular transport, and developmental changes. J. Cell Biol. 99, 2082-2091.
145. MacCalman, C. D., Bardeesy, N., Holland, P. C., and Blaschuk, O. W. (1992). Noncoordinate developmental regulation of N-cadherin, N-CAM, integrin and fibronectin mRNA levels during myoblast terminal differentiation. Dev. Dyn. 195, 127-132.
146. Machado, C., and Andrew, D. J. (2000). D-Titin: A giant protein with dual roles in chromosomes and muscles. J. Cell Biol. 151, 639-652.
147. Maeland A. D., Bloor, J. W., and Brown, N. H. (1996). Characterization of singles bar a new mutant in Drosophila melanogaster required for muscle development. Mol. Biol. Cell 7, 39a.
148. Matsuda, M., and Kurata, T. (1996). Emerging components of the Crk oncogene product: The first identified adaptor protein. Cell. Signal. 8, 335-340.
149. Mayer, A. (2001). What drives membrane fusion in eukaryotes? Trends Biochem. Sci. 26, 717-723.
150. Mayer, B. J., and Hanafusa, H. (1990). Mutagenic analysis of the v-crk oncogene: Requirement for SH2 and SH3 domains and correlation between increased cellular phosphotyrosine and transformation. J. Virol. 64, 3581-3589.
151. Mege, R. M., Goudou, D., Diaz, C., Nicolet, M., Garcia, L., Geraud, G., and Rieger, F. (1992). N-cadherin and N-CAM in myoblast fusion: Compared localisation and effect of blockade by peptides and antibodies. J. Cell Sci. 103, 897-906.
152. Menon, S. D., and Chia, W. (2001). Drosophila rolling pebbles: A multidomain protein required for myoblast fusion that recruits D-Titin in response to the myoblast attractant Dumbfounded. Dev. Cell 1, 691-703.
153. Michelson, A. M., Abmayr, S. M., Bate, M., Martinez Arias, A., and Maniatis, T. (1990). Expression of a MyoD family member prefigures muscle pattern in Drosophila embryos. Genes Dev. 4, 2086-2097.
154. Molkentin, J. D., and Olson, E. N. (1996). Combinatorial control of muscle development by basic helix-loop-helix and MADS-box transcription factors. Proc. Natl. Acad. Sci. USA 93, 9366-9373.
155. Moore, R., and Walsh, F. S. (1993). The cell adhesion molecule M-cadherin is specifically expressed in developing and regenerating, but not denervated skeletal muscle. Development 117, 1409-1420.
156. Moore, S. E., Thompson, J., Kirkness, V., Dickson, J. G., and Walsh, F. S. (1987). Skeletal muscle neural cell adhesion molecule (N-CAM): Changes in protein and mRNA species during myogenesis of muscle cell lines. J. Cell Biol. 105, 1377-1386.
157. Morris, G. E., and Head, L. P. (1985). Monoclonal antibodies to intermediate filaments in chick muscle cell cultures. Exp. Cell Res. 158, 177-191.
158. Moscoso, L. M., Cremer, H., and Sanes, J. R. (1998). Organization and reorganization of neuromuscular junctions in mice lacking neural cell adhesion molecule, tenascin-C, or fibroblast growth factor-5. J. Neurosci. 18, 1465-1477.
159. Nakanishi, M., Hirayama, E., and Kim, J. (2001). Characterisation of myogenic cell membrane: II. Dynamic changes in membrane lipids during the differentiation of mouse C2 myoblast cells. Cell Biol. Int. 25, 971-979.
160. Nakornchai, S., Falconer, A. R., Fisher, D., Goodall, A. H., Hallinan, T., and Lucy, J. A. (1981). Effects of retinol, fatty acids and glycerol monooleate on the fusion of chick embryo myoblasts in vitro. Biochim. Biophys. Acta 643, 152-160.
161. Nameroff, M., and Munar, E. (1976). Inhibition of cellular differentiation by phospholipase C. II. Separation of fusion and recognition among myogenic cells. Dev. Biol. 49, 288-293.
162. Nameroff, M., Trotter, J. A., Keller, J. M., and Munar, E. (1973). Inhibition of cellular differentiation by phospholipase C. I. Effects of the enzyme on myogenesis and chondrogenesis in vitro. J. Cell Biol. 58, 107-118.
163. Nishihara, H., Kobayashi, S., Hashimoto, Y., Ohba, F., Mochizuki, N., Kurata, T., Nagashima, K., and Matsuda, M. (1999). Non-adherent cell-specific expresion of DOCK2, a member of the human CDM-family proteins. Biochim. Biophys. Acta 1452, 179-187.
164. Nishizuka, Y. (1986). Studies and perspectives of protein kinase C. Science 233, 305-312.
165. Nolan, K. M., Barrett, K., Lu, Y., Hu, K.-Q., Vincent, S., and Settleman, J. (1998). Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev. 12, 3337-3342.
166. Nose, A., Isshiki, T., and Takeichi, M. (1998). Regional specification of muscle progenitors in Drosophila: The role of the msh homeobox gene. Development 125, 215-223.
167. Oda, H., Uemura, T., Harada, Y., Iwai, Y., and Takeichi, M. (1994). A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell-cell adhesion. Dev. Biol. 165, 716-726.
168. Olson, E. N., Perry, M., and Schulz, R. A. (1995). Regulation of muscle differentiation by the MEF2 family of MADS box transcription factors. Dev. Biol. 172, 2-14.
169. Ontell, M., and Kozeka, K. (1984). The organogenesis of murine striated muscle: A cytoarchitectural study. Am. J. Anat. 171, 133-148.
170. Paine, M. J., Desmond, H. P., Theakston, R. D., and Crampton, J. M. (1992). Purification, cloning, and molecular characterization of a high molecular weight hemorrhagic metalloprotease, jararhagin, from Bothrops jararaca venom. Insights into the disintegrin gene family. J. Biol. Chem. 267, 22869-22876.
171. Patel, B. N., and Van Vactor, D. L. (2002). Axon guidance: The cytoplasmic tail. Curr. Opin. Cell Biol. 14, 221-229.
172. Paterson, B. M., Walldorf, U., Eldridge, J., Dubendorfer, A., Frasch, M., and Gehring, W. J. (1991). The Drosophila homologue of vertebrate myogenic-determination genes encodes a transiently expressed nuclear protein marking primary myogenic cells. Proc. Natl. Acad. Sci USA 88, 3782-3786.
173. Paululat, A., Burchard, S., and Renkawitz-Pohl, R. (1995). Fusion from myoblasts to myotubes is dependent on the rolling stone gene (rost) of Drosophila. Development 121, 2611-2620.
174. Paululat, A., Goubeaud, A., Damm, C., Knirr, S., Burchard, S., and Renkawitz-Pohl, R. (1997). The mesodermal expression of rolling stone (rost) is essential for myoblast fusion in Drosophila and encodes a potential transmembrane protein. J. Cell Biol. 138, 337-348.
175. Paululat, A., Holz, A., and Renkawitz-Pohl, R. (1999). Essential genes for myoblast fusion in Drosophila embryogenesis. Mech. Dev. 83, 17-26.
176. Peck, D., and Walsh, F. S. (1993). Differential effects of over-expressed neural cell adhesion molecule isoforms on myoblast fusion. J. Cell Biol. 123, 1587-1595.
177. Peuvot, J., Schanck, A., Lins, L., and Brasseur, R. (1999). Are the fusion processes involved in birth, life and death of the cell depending on tilted insertion of peptides into membranes? J. Theor. Biol. 198, 173-181.
178. Pfenninger, K. H., and Bunge, R. P. (1974). Freeze-fracturing of nerve growth cones and young fibers. A study of developing plasma membrane. J. Cell Biol. 63, 180-196.
179. Pinto da Silva, P., and Nogueira, M. L. (1977). Membrane fusion during secretion. A hypothesis based on electron microscope observation of Phytophthora palmivora zoospores during encystment. J. Cell Biol. 73, 161-181.
180. Podleski, T. R., Greenberg, I., Schlessinger, J., and Yamada, K. M. (1979). Fibronectin delays the fusion of L6 myoblasts. Exp. Cell Res. 122, 317-326.
181. Poste, G., and Allison, A. C. (1973). Membrane fusion. Biochim. Biophys. Acta 300, 421-465.
182. Pouliot, Y., Holland, P. C., and Blaschuk, O. W. (1990). Developmental regulation of a cadherin during the differentiation of skeletal myoblasts. Dev. Biol. 141, 292-298.
183. Pouliot, Y., Gravel, M., and Holland, P. C. (1994). Developmental regulation of M-cadherin in the terminal differentiation of skeletal myoblasts. Dev. Dyn. 200, 305-312.
184. Primakoff, P., and Myles, D. G. (2000). The ADAM gene family: Surface proteins with adhesion and protease activity. Trends Genet. 16, 83-87.
185. Primakoff, P., Hyatt, H., and Tredick-Kline, J. (1987). Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion. J. Cell Biol. 104, 141-149.
186. Prives, J. (1993). Calcium signal transduction pathway and myoblast fusion. In "Signal Transduction during Biomembrane Fusion" (D. H. O'Day, Ed.), pp. 181-195. Academic Press, San Diego, CA.
187. Prives, J., and Shinitzky, M. (1977). Increased membrane fluidity precedes fusion of muscle cells. Nature 268, 761-763.
188. Prokop, A., Landgraf, M., Rushton, E., Broadie, K., and Bate, M. (1996). Presynaptic development at the Drosophila neuromuscular junction: Assembly and localization of presynaptic active zones. Neuron 17, 617-626.
189. Radice, G. L., Rayburn, H., Matsunami, H., Knudsen, K. A., Takeichi, M., and Hynes, R. O. (1997). Developmental defects in mouse embryos lacking N-cadherin. Dev. Biol. 181, 64-78.
190. Ramos, R. G., Igloi, G. L., Lichte, B., Baumann, U., Maier, D., Schneider, T., Brandstatter, J. H., Frohlich, A., and Fischbach, K. E (1993). The irregular chiasm C-roughest locus of Drosophila, which affects axonal projections and programmed cell death, encodes a novel immunoglobulin-like protein. Genes Dev. 7, 2533-2547.
191. Ranganayakulu, G., Zhao, B., Dokidis, A., Molkentin, J. D., Olson, E. N., and Schulz, R. A. (1995). A series of mutations in the D-MEF2 transcription factor reveal multiple functions in larval and adult myogenesis in Drosophila. Dev. Biol. 171, 169-181.
192. Rapuano, M., Ross, A. F., and Prives, J. (1989). Opposing effects of calcium entry and phorbol esters on fusion of chick muscle cells. Dev. Biol. 134, 271-278.
193. Rash, J. E., and Fambrough, D. (1973). Ultrastructural and electrophysiological correlates of cell coupling and cytoplasmic fusion during myogenesis in vitro. Dev. Biol. 30, 166-186.
194. Rau, A., Buttgereit, D., Holz, A., Fetter, R., Doberstein, S. K., Paululat, A., Staudt, N., Skeath, J., Michelson, A. M., and Renkawitz-Pohl, R. (2001). rolling pebbles (rols) is required in Drosophila muscle precursors for recruitment of myoblasts for fusion. Development 128, 5061-5073.
195. Reddien, P. W., and Horvitz, H. R. (2000). CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in C. elegans. Nat. Cell Biol. 2, 131-136.
196. Ridley, A. J., and Hall, A. (1992). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70, 389-399.
197. Rose, O., Rohwedel, J., Reinhardt, S., Bachmann, M., Cramer, M., Rotter, M., Wobus, A., and Starzinski-Powitz, A. (1994). Expression of M-cadherin protein in myogenic cells during prenatal mouse development and differentiation of embryonic stem cells in culture. Dev. Dyn. 201, 245-259.
198. Rose, O., Grund, C., Reinhardt, S., Starzinski-Powitz, A., and Franke, W. W. (1995). Contactus adherens, a special type of plaque-bearing adhering junction containing M-cadherin, in the granule cell layer of the cerebellar glomerulus. Proc. Natl. Acad. Sci. USA 92, 6022-6026.
199. Rosen, G. D., Sanes, J. R., LaChance, R., Cunningham, J. M., Roman, J., and Dean, D. C. (1992). Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Cell 69, 1107-1119.
200. Rosenthal, N. (1989). Muscle cell differentiation. Curr. Opin. Cell Biol. 1, 1094-1101.
201. Rudnicki, M., and Jaenisch, R. (1995). The MyoD family of transcription factors and skeletal myogenesis. BioEssays 17, 203-209.
202. Ruiz-Gomez, M., Coutts, N., Price, A., Taylor, M. V., and Bate, M. (2000). Drosophila Dumbfounded: A myoblast attractant essential for fusion. Cell 102, 189-198.
203. Ruiz-Gomez, M., Coutts, N., Suster, M. L., Landgraf, M., and Bate, M. (2002). myoblasts incompetent encodes a zinc finger transcription factor required to specify fusion-competent myoblasts in Drosophila. Development 129, 133-141.
204. Rushton, E., Drysdale, R., Abmayr, S. M., Michelson, A. M., and Bate, M. (1995). Mutations in a novel gene, myoblast city, provide evidence in support of the founder cell hypothesis for Drosophila muscle development. Development 121, 1979-1988.
205. Sandra, A., Leon, M. A., and Przybylski, R. J. (1977). Suppression of myoblast fusion by concanavalin A: Possible involvement of membrane fluidity. J. Cell Sci. 28, 251-272.
206. Sanger, J. W. (1974). The use of cytochalasin B to distinguish myoblasts from fibroblasts in cultures of developing chick striated muscle. Proc. Natl. Acad. Sci. USA 71, 3621-3625.
207. Sanger, J. W., and Holtzer, H. (1972). Cytochalasin B: Effects on cell morphology, cell adhesion, and mucupolysaccharide synthesis. Proc. Natl. Acad. Sci. USA 69, 253-257.
208. Sanger, J. W., Holtzer, S., and Holtzer, H. (1971). Effects of cytochalasin B on muscle cells in tissue culture. Nature 229, 121-123.
209. San Martin, B., and Bate, M. (2001). Hindgut visceral mesoderm requires an ectodermal template for normal development in Drosophila. Development 128, 233-242.
210. Schudt, C., van der Bosch, J., and Pette, D. (1973). Inhibition of muscle cell fusion in vitro by Mg2+ and K+- ions. FEBS Lett, 32, 296-298.
211. Schutzle, U. B., Wakelam, M. J., and Pette, D. (1984). Prostaglandins and cyclic AMP stimulate creatine kinase synthesis but not fusion in cultured embryonic chick muscle cells. Biochim. Biophys. Acta 805, 204-210.
212. Seale, P., Asakura, A., and Rudnicki, M. A. (2001). The potential of muscle stem cells. Dev. Cell 1, 333-342.
213. Sessions, A., and Horwitz, A. F. (1981). Myoblast aminophospholipid asymmetry differs from that of fibroblasts. FEBS Lett. 134, 75-78.
214. Sessions, A., and Horwitz, A. F. (1983). Differentiation-related differences in the plasma membrane phospholipid asymmetry of myogenic and fibrogenic cells. Biochim. Biophys. Acta 728, 103-111.
215. Settleman, J. (2001). Rac 'n Rho: The music that shapes a developing embryo. Dev. Cell 1, 321-331.
216. Shimada, Y. (1971). Electron microscope observations on the fusion of chick myoblasts in vitro. J. Cell Biol. 48, 128-142.
217. Sink, H., Rehm, E. J., Richstone, L., Bulls, Y. M., and Goodman, C. S. (2001). sidestep encodes a target-derived attractant essential for motor axon guidance in Drosophila. Cell 105, 57-67.
218. Sorkin, B. C., Hoffman, S., Edelman, G. M., and Cunningham, B. A. (1984). Sulfation and phosphorylation of the neural cell adhesion molecule, N-CAM. Science 225, 1476-1478.
219. Steiner, S., Manley, G., and Adams, T. (1984). Effect of inhibitors of the lipoxygenase pathway on mouse myoblast fusion. Exp. Cell Res. 155, 289-293.
220. Strunkelnberg, M., Bonengel, B., Moda, L. M., Hertenstein, A., de Couet, H. G., Ramos, R. G., and Fischbach, K. F. (2001). rst and its paralogue kirre act redundantly during embryonic muscle development in Drosophila. Development 128, 4229-4239.
221. Tajbakhsh, S., Rocancourt, D., Cossu, G., and Buckingham, M. (1997). Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD. Cell 89, 127-138.
222. Tao, J. X., and Ip, W. (1991). Site-specific antibodies block kinase A phosphorylation of desmin in vitro and inhibit incorporation of myoblasts into myotubes. Cell Motil. Cytoskeleton 19, 109-120.
223. Taylor, G. M., and Sanders, D. A. (1999). The role of the membrane-spanning domain sequence in glycoprotein-mediated membrane fusion. Mol. Biol. Cell 10, 2803-2815.
224. Taylor, M. V. (2000). Muscle development: Molecules of myoblast fusion. Curr. Biol. 10, R646-648.
225. Taylor, M. V. (2002a). Drosophila development: Novel signal elicits visceral response. Curr. Biol. 12, R102-104.
226. Taylor, M. V. (2002b). Muscle differentiation: How two cells become one. Curr. Biol. 12, R224-228.
227. Taylor, M. V., Beatty, K. E., Hunter, H. K., and Baylies, M. K. (1995). Drosophila MEF2 is regulated by twist and is expressed in both the primordia and differentiated cells of the embyronic somatic, visceral and heart musculature. Mech. Dev. 50, 29-41.
228. Temm-Grove, C. J., Wert, D., Thompson, V. F., Allen, R. E., and Goll, D. E. (1999). Microinjection of calpastatin inhibits fusion in myoblasts. Exp. Cell Res. 247, 293-303.
229. Tepass, U., Gruszynski-DeFeo, E., Haag, T. A., Omatyar, L., Torok, T., and Hartenstein, V. (1996). shotgun encodes Drosophila E-cadherin and is preferentially required during cell rearrangement in the neurectoderm and other morphogenetically active epithelia. Genes Dev. 10, 672-685.
230. Toutant, M., and Sobel, A. (1987). Protein phosphorylation in response to the tumor promoter TPA is dependent on the state of differentiation of muscle cells. Dev. Biol. 124, 370-378.
231. Trinick, J., and Tskhovrebova, L. (1999). Titin: A molecular control freak. Trends Cell Biol. 9, 377-380.
232. Uemura, T., Oda, H., Kraut, R., Hayashi, S., Kotaoka, Y., and Takeichi, M. (1996). Zygotic Drosophila E-cadherin expression is required for processes of dynamic epithelial cell rearrangement in the Drosophila embryo. Genes Dev. 10, 659-671.
233. van den Eijnde, S. M., van den Hoff, M. J., Reutelingsperger, C. P., van Heerde, W. L., Henfling, M. E., Vermeij-Keers, C., Schutte, B., Borgers, M., and Ramaekers, F. C. (2001). Transient expression of phosphatidylserine at cell-cell contact areas is required for myotube formation. J. Cell Sci. 114, 3631-3642.
234. 2+ on the rate of muscle cell fusion. Exp. Cell Res. 82, 433-438.
235. van Meer, G. (1989). Lipid traffic in animal cells. Annu. Rev. Cell Biol. 5, 247-275.
236. Venuti, J. M., and Cserjesi, P. (1996). Molecular embryology of skeletal myogenesis. In "Current Topics in Developmental Biology". (R. A. Pedersen and G. P. Schatten, Eds.), pp. 169-206. Academic Press, San Diego, CA.
237. Wakelam, M. J. (1983). Inositol phospholipid metabolism and myoblast fusion. Biochem. J. 214, 77-82.
238. Wakelam, M. J. O, (1985). The fusion of myoblasts. Biochem. J. 228, 1-12.
239. 2+. Biochem. J. 202, 723-729.
240. Walsh, F. S., and Phillips, E. (1981). Specific changes in cellular glycoproteins and surface proteins during myogenesis in clonal muscle cells. Dev. Biol. 81, 229-237.
241. Ward, S., Argon, Y., and Nelson, G. A. (1981). Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans. J. Cell Biol. 91, 26-44.
242. Weidekamm, E., Schudt, C., and Brdiczka, D. (1976). Physical properties of muscle cell membranes during fusion. A fluorescence polarization study with the ionophore A23187. Biochim. Biophys. Acta 443, 169-180.
243. Weintraub, H., Davis, R., Tapscott, S., Thayer, M., Krause, M., Benezra, R., Blackwell, T. K., Turner, D., Rupp, R., Hollenberg, S., Zhuang, Y., and Lassar, A. (1991). The myoD gene family: Nodal point during specification of the muscle cell lineage. Science 251, 761-766.
244. Wilson, S. J., McEwan, J. C., Sheard, P. W., and Harris, A. J. (1992). Early stages of myogenesis in a large mammal: Formation of successive generations of myotubes in sheep tibialis cranialis muscle. J. Muscle Res. Cell Motil. 13, 534-550.
245. Wolfsberg, T. G., and White, J. M. (1996). ADAMs in fertilization and development. Dev. Biol. 180, 389-401.
246. Wong, K., Ren, X. R., Huang, Y. Z., Xie, Y., Liu, G., Saito, H., Tang, H., Wen, L., Brady-Kalnay, S. M., Mei, L., Wu, J. Y., Xiong, W. C., and Rao, Y. (2001). Signal transduction in neuronal migration: Roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. Cell 107, 209-221.
247. Wood, G. K., Tomasiewicz, H., Rutishauser, U., Magnuson, T., Quirion, R., Rochford, J., and Srivastava, L. K. (1998). NCAM-180 knockout mice display increased lateral ventricle size and reduced prepulse inhibition of startle. Neuroreport 9, 461-466.
248. Wu, Y. C., and Horvitz, H. R. (1998). C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392, 501-504.
249. Yaffe, D. (1971). Developmental changes preceding cell fusion during muscle differentiation in vitro. Exp. Cell Res. 66, 33-48.
250. Yagami-Hiromasa, T., Sato, T., Kurisaki, T., Kamijo, K., Nabeshima, Y., and Fujisawa-Sehara, A. (1995). A metalloprotease-disintegrin participating in myoblast fusion. Nature 377, 652-656.
251. Yeagle, P. L. (1985). Cholesterol and the cell membrane. Biochim. Biophys. Acta 822, 267-287.
252. Young, P. E., Richman, A. M., Ketchum, A. S., and Kiehart, D. P. (1993). Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function. Genes Dev. 7, 29-41.
253. Yun, K., and Wold, B. (1996). Skeletal muscle determination and differentiation: Story of a core regulatory network and its context. Curr. Opin. Cell Biol. 8, 877-889.
254. Zalin, R. J. (1977). Prostaglandins and myoblast fusion. Dev. Biol. 59, 241-248.
255. Zalin, R. J. (1987). The role of hormones and prostanoids in the in vitro proliferation and differentiation of human myoblasts. Exp. Cell Res. 172, 265-281.
256. Zeschnigk, M., Kozian, D., Kuch, C., Schmoll, M., and Starzinski-Powitz, A. (1995). Involvement of M-cadherin in terminal differentiation of skeletal muscles. J. Cell Sci. 108, 2973-2981.
257. Zhang, Y., Featherstone, D., Davis, W., Rushton, E., and Broadie, K. (2000). Drosophila D-titin is required for myoblast fusion and skeletal muscle striation. J. Cell Sci. 113, 3103-3115.
258. Zimmerberg, J. (2001). How can proteolipids be central players in membrane fusion? Trends Cell Biol. 11, 233-235.
259. Zimmerberg, J., Vogel, S. S., and Chernomordik, L. V. (1993). Mechanisms of membrane fusion. Annu. Rev. Biophys. Biomol. Struct. 22, 433-466.