What drives membrane fusion in eukaryotes?

Trends in Biochemical Sciences

Volumn 26, Issue 12, 2001, Pages 717-723

  Mayer, Andreas ^a  

^a FRIEDRICH MIESCHER LABORATORY OF THE MAX PLANCK SOCIETY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; LIPID; PROTEIN; RAB PROTEIN;

CELL ORGANELLE; EUKARYOTIC CELL; EXOCYTOSIS; EXPERIMENTAL MODEL; LIPID BILAYER; MEMBRANE BINDING; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TRANSPORT; REVIEW; SACCHAROMYCES CEREVISIAE;

ANIMALS; BIOLOGICAL TRANSPORT; ENDOCYTOSIS; EUKARYOTIC CELLS; EXOCYTOSIS; INTRACELLULAR MEMBRANES; LIPID BILAYERS; MACROMOLECULAR SUBSTANCES; MEMBRANE FUSION; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; PROTEIN TRANSPORT; SNARE PROTEINS; VESICULAR TRANSPORT PROTEINS;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0035663883     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)01984-3     Document Type: Review

References (59)

1. Protein complexes in transport vesicle targeting
2. SNAREs and the specificity of membrane fusion
3. Rab proteins as membrane organizers
4. Membrane fusion and exocytosis
5. Structure and function of fusion pores in exocytosis and ectoplasmic membrane fusion
6. How can proteolipids be central players in membrane fusion?
7. Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy
8. Coiled coils in both intracellular vesicle and viral membrane fusion
9. Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
10. Yeast mitochondrial dynamics: Fusion, division, segregation, and shape
11. Mitochondrial transmission during mating in Saccharomyces cerevisiae is determined by mitochondrial fusion and fission and the intramitochondrial segregation of mitochondrial DNA
12. SNAREpins: Minimal machinery for membrane fusion
13. Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors
14. Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs
15. Mimicry and mechanism in phospholipid models of membrane fusion
16. Geranylgeranylated SNAREs are dominant inhibitors of membrane fusion
17. The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion
18. 2+ and drives membrane fusion
19. 2+-dependent steps leading to secretion in chromaffin cells from mouse adrenal slices
20. Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis
21. Exocytic mechanism studied by truncated and zero layer mutants of the C-terminus of SNAP-26
22. Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity
23. Ordering the final events in yeast exocytosis
24. Calcium can disrupt the SNARE protein complex on sea urchin egg secretory vesicles without irreversibly blocking fusion
25. 2+ sensitivity
26. Homotypic vacuolar fusion mediated by t- and v-SNAREs
27. Defining the functions of trans-SNARE pairs
28. SNAREpins are functionally resistant to disruption by NSF and α-SNAP
29. Vacuole acidification is required for trans-SNARE pairing, LMA1 release, and homotypic fusion
30. Trans-complex formation of proteolipid channels in the terminal phase of membrane fusion
31. 2+/calmodulin signals the completion of docking and triggers a late step of vacuole fusion
32. Control of the terminal step of membrane fusion by protein phosphatase 1
33. +-ATPase
34. Animal plasma membrane energization by chemiosmotic H+ V-ATPases
35. Calmodulin regulates endosome fusion
36. Regulation of intra-Golgi transport by calcium
37. 2+ in late endosome-lysosome heterotypic fusion and in the reformation of lysosomes from hybrid organelles
38. 2+ sensitivity on secretory exocytosis
39. Distinct effects of α-SNAP, 14-3-3 proteins, and calmodulin on priming and triggering of regulated exocytosis
40. 2+-stimulated secretion by modulating membrane-attached exocytic machinery
41. 2+ and GTP: Essential components in vesicular trafficking between the endoplasmic reticulum and Golgi apparatus
42. Fusion of endosomes involved in synaptic vesicle recycling
43. Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles
44. Synaptic vesicle membrane proteins interact to form a multimeric complex
45. The V0 sector of the V-ATPase, synaptobrevin, and synaptophysin are associated on synaptic vesicles in a Triton X-100-resistant, freeze-thawing sensitive complex
46. Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast
47. Isolation and characterization of SYS genes from yeast, multicopy suppressors of the functional loss of the transport GTPase Ypt6p
48. Got1p and Sft2p: Membrane proteins involved in traffic to the Golgi complex
49. Staurosporine blocks evoked release of FM1-44 but not acetylcholine from frog motor nerve terminals
50. The exocytotic event in chromaffin cells revealed by patch amperometry
51. In vitro reconstitution of neurotransmitter release
52. 2+ and protein kinase C via distinct mechanisms
53. The 'focal membrane fusion' model revisited: Toward a unifying structural concept of biological membrane fusion
54. Increase in the number of presynaptic large intramembrane particles during synaptic transmission at the Torpedo nerve-electroplaque junction
55. Bending membranes to the task: Structural intermediates in bilayer fusion
56. Organelle membrane fusion: A novel function for the syntaxin homolog Ufe1p in ER membrane fusion
57. The translocon: A dynamic gateway at the ER membrane
58. ER membrane protein complex required for nuclear fusion
59. Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiae