Are the fusion processes involved in birth, life and death of the cell depending on tilted insertion of peptides into membranes?

Journal of Theoretical Biology

Volumn 198, Issue 2, 1999, Pages 173-181

  Peuvot, Jacques ^a   Schanck, André ^b   Lins, Laurence ^c   Brasseur, Robert ^c  

^a UCB PHARMA   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PEPTIDE; VIRUS HEMAGGLUTININ;

CAENORHABDITIS ELEGANS; CELL DEATH; EBOLA VIRUS; HEPATITIS B VIRUS; INFESTATION; INFLUENZA VIRUS; MEMBRANE FUSION; MEMBRANE STABILIZATION; MEMBRANE STRUCTURE; MOLECULAR MODEL; MUSCLE DEVELOPMENT; PLASMODIUM; PRIORITY JOURNAL; PROTEIN TRANSPORT; REVIEW; RUBELLA VIRUS; VIRUS INFECTION;

CAENORHABDITIS ELEGANS; EBOLA VIRUS; HEPATITIS B VIRUS; INFLUENZA VIRUS; RUBELLA VIRUS;

EID: 0033591307     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.1999.0908     Document Type: Article

References (64)

1. Arends, M. J. & Wyllie, A. H. (1991). Apoptosis: Mechanisms and roles in pathology. Int. Rev. Exp. Pathol. 32, 223-254.
2. Arruda, S., Bomfim, G., Knights, R., Huima-Byron, T. & Riley, L. W. (1993). Cloning of an M. tuberculosis DNA fragment associated with entry and survival inside cells. Science 261, 1454-1457.
3. Blobel, C. P., Myles, D. G., Primakoff, P. & White, J. M. (1990). Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence. J. Cell Biol. 111, 69-78.
4. Blobel, C. P., Wolfsberg, T. G., Turck, C. W., Myles, D. G., Primakoff, P. & White, J. M. (1992). A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion. Nature 356, 248-252.
5. Boël, P., Wildmann, C., Sensi, M.-L., Brasseur, R., Renauld, J.-C., Coulie, P., Boon, T. & Van Der Bruggen, P. (1995). BAGE: A new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes. Immunity 2, 167-175.
6. Brasseur, R. (1991). Differentiation of lipid-associating helices by use of three-dimensional molecular hydrophobicity potential calculations. J. Biol. Chem. 24, 16120-16127.
7. Brasseur, R. & Ruysschaert, J. M. (1986). Conformation and mode of organization of amphiphilic membrane components : A conformational analysis. Biochem. J. 238, 1-11.
8. Brasseur, R., Vandenbranden, M., Cornet, B., Burny, A. & Ruysschaert, J. M. (1990). Orientation into the lipid bilayer of an asymmetric amphipathic helical peptide located at the N-terminus of viral fusion proteins. Biochim. Biophys. Acta 1029, 267-273.
9. Brasseur, R., Vanloo, B., Deleys, R., Lins, L., Labeur, C., Taveirne, J., Ruysschaert, J. M. & Rosseneu, M. (1993). Synthetic model peptides for apolipoproteins. I. Design and properties of synthetic model peptides for the amphipathic helices of the plasma apolipoproteins. Biochim. Biophys. Acta 1170, 1-7.
10. Brasseur, R., Pillot, T., Lins, L., Vandekerckhove, J. & Rosseneu, M. (1997). Peptides in membranes: Tipping the balance of membrane stability. Trends Biochem. Sci. 22, 167-171.
11. Briggs, M. S., Cornell, D. G., Dluhy, R. A. & Gierasch, L. M. (1986). Conformations of signal peptides induced by lipids suggest initial steps in protein export. Science 233, 206-208.
12. Cerami, C., Frevert, U., Sinnis, P., Takacs, B., Clavijo, P., Santos, M. J. & Nussenzweig, V. (1992). The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein of plasmodium falciparum sporozoites. Cell 70, 1021-1033.
13. Chernomordik, L. V., Leikina, E., Frolov, V., Bronk, P. & Zimmerberg, J. (1997). An early stage of membrane fusion mediated by the low pH conformation of influenza hemagglutinin depends upon membrane lipids. J. Cell Biol. 136, 81-93.
14. Ducarme, Ph., Rahman, M. & Brasseur, R. (1998). IMPALA: A simple restraint field to simulate the biological membrane in molecular structure studies. Protein-struct. Funct. & Genet. 30, 357-371.
15. Ellens, H., Siegel, D. P., Alford, D., Yeagle, P. L., Boni, L., Lis, L. J., Quinn, P. J. & Bentz, J. (1989). Membrane fusion and inverted phases. Biochemistry 28, 3692-3703.
16. Epand, R. M., Cheetham, J. J., Epand, R. F., Yeagle, P. L., Richardson, C. D., Rockwell, A. & Degrado, W. F. (1992). Peptide models for the membrane destabilizing actions of viral fusion proteins. Biopolymers 32, 309-314.
17. Gaillard, J. L., Berche, P., Frebel, C., Gouin, E. & Cossart, P. (1991). Entry of L. Monocytogenes into cells is mediated by internalin, a repeat-protein reminiscent of surface antigens from gram-positive cocci. Cell 65, 1127-1141.
18. Gallaher, W. R., Segrest, J. P. & Hunter, E. (1992). Are fusion peptides really "sided" insertional helices? Cell 70, 531-532.
19. + ALL involve GTPase-activating protein, phospholipase C-γ1, and phosphatidylinositol 3′-kinase. Leukemia 8, 115-120.
20. Grignani, F., De Matteis, S., Nervi, C., Tomassoni, L., Gelmetti, V., Cioce, M., Fanelli, M., Ruthardt, M., Ferrara, F., Zamir, I., Seiser, C., Grignani, F., Lazar, M. A., Minucci, S. & Pelicci, P. G. (1998). Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia. Nature 391, 815-818.
21. Harter, C., James, P., Bachi, T., Semenza, G. & Brunner, J. (1989). Hydrophobic binding of the ectodomain of influenza hemagglutinin to membranes occurs through the "Fusion Peptide". J. Biol. Chem. 264, 6459-6464.
22. Horth, M., Lambrecht, B., Chuah Lay Khim, M., Bex, F., Thiriart, C., Ruysschaert, J. M., Burny, A. & Brasseur, R. (1991). Theoretical and functional analysis of the SIV fusion peptide. EMBO J. 10, 2747-2755.
23. Hu, P., Hornick, J. L., Glasky, M. S., Yun, A., Milkie, M. N., Khawli, L. A., Anderson, P. M. & Epstein, A. L. (1996). A chimeric lym-1/interleukin 2 fusion protein for increasing tumor vascular permeability and enhancing antibody uptake. Cancer Res. 56, 4998-5004.
24. Huovila, A-P. J., Almeida, E. A. C. & White, J. M. (1996). ADAMs and cell fusion. Curr. Opin. Cell Biol. 8, 692-699.
25. Isberg, R. R., Voorhis, D. L. & Falkow, S. (1987). Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells. Cell 50, 769-778.
26. Ishiguro, R., Kimura, N. & Takahashi, S. (1993). Orientation of fusion-active synthetic peptides in phospholipid bilayers: Determination by Fourier transform infrared spectroscopy. Biochemistry 32, 9792-9797.
27. Killian, J. A., De Jong, A. M. Ph., Bijvelt, J., Verkleij, A. J. & De Kruijff, B. (1990). Induction of non-bilayer lipid structures by functional signal peptides. EMBO J. 9, 815-819.
28. Le, L., Brasseur, R., Wemers, C., Meulemans, G. & Burny, A. (1988). Fusion(F) protein gene of newcastle disease virus: Sequence and hydrophobicity comparative analysis between virulent and avirulent strains. Virus Genes 1(4), 333-350.
29. 2-terminus of influenza HA-2. J. Biol. Chem. 262, 6500-6505.
30. Lingnau, A., Domann, E., Hudel, M., Bock, M., NichterLein, T., Wehland, J. & Chakraborty, T. (1995). Expression of the Listeria monocytogenes EGD inLA and inLB genes, whose products mediate bacterial entry into tissue culture cell lines, by PrfA-dependent and -independent mechanisms. Infec. Immunity 63, 3896-3903.
31. Lingnau, A., Chakraborty, T., Niebuhr, K., Domann, E. & Wehland, J. (1996). Identification and purification of novel internalin-related proteins in Listeria monocytogenes and Listeria ivanovii. Infec. Immunity 64, 1002-1006.
32. Longo, M. L., Waring, A. J. & Hammer, D. A. (1997). Interaction of the influenza hemagglutinin fusion peptide with lipid bilayers: Area expansion and permeation. Biophys. J. 73, 1430-1439.
33. Macosko, J. C., Kim, C-H. & Shin, Y-K. (1997). The membrane topology of the fusion peptide region of influenza hemagglutinin determined by spin-labeling EPR. J. Mol. Biol. 267, 1139-1148.
34. 2-terminal SIV fusion peptide into the lipid bilayer. FEBS Lett. 333, 325-330.
35. 2-terminal extremity of simian immunodeficiency virus gp32 and their mode of insertion into the lipid bilayer: An infrared spectroscopy study. J. Virol. 68(2), 1139-1148.
36. Menard, R., Sultan, A. A., Cortes, C., Altszuler, R., van Dijk, M. R., Janse, C. J., Waters, A. P., NussenZweig, R. S. & Nussenzweig, V. (1997). Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes. Nature 385, 336-340.
37. Muga, A., Neugebauer, W., Hirama, T. & Surewicz, W. K. (1994). Membrane interaction and conformational properties of the putative fusion peptide of PH-30, a protein active in sperm-egg fusion. Biochemistry 33, 4444-4448.
38. Munoz-Barroso, I., Durell, S., Sakaguchi, K., Appella, E. & Blumenthal, R. (1998). Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41. J. Cell Biol. 140, 315-323.
39. Myles, D. G. & Primakoff, P. (1997). Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg. Biol. Reprod. 56, 320-327.
40. Myles, D. G., Kimmel, L. H., Blobel, C. P., White, J. M. & Primakoff, P. (1994). Identification of a binding site in the disintegrin domain of fertilin required for sperm-egg fusion. Proc. Nat. Acad. Sci. U.S.A. 91, 4195-4198.
41. Nieva, J. L., Nir, S., Muga, A., Goni, F. M. & Wilschut, J. (1994). Interaction of the HIV-1 fusion peptide with phospholipid vesicles: Different structural requirements for fusion and leakage. Biochemistry 33, 3201-3209.
42. Ortega-Barria, E. & Pereira, M. E. A. (1991). A novel T. cruzi heparin-binding protein promotes fibroblast adhesion and penetration of engineered bacteria and trypanosomes into mammalian cells. Cell 67, 411-421.
43. Pereira, F. B., Goni, F. M., Muga, A. & Nieva, J. L. (1997). Permeabilization and fusion of uncharged lipid vesicles induced by the HIV-1 fusion peptide adopting an extended conformation: Dose and sequence effects. Biophys. J. 73, 1977-1986.
44. Pillot, T., Goethals, M., Vanloo, B., Talussot, C., Brasseur, R., Vendekerckhove, J., Rosseneu, M. & Lins, L. (1996). Fusogenic properties of the C-terminal domain of the Alzheimer β-amyloid peptide. J. Biol. Chem. 271, 28757-28765.
45. Pillot, T., Lins, L., Goethals, M., Vanloo, B., Baert, J., Vandekerckhove, J., Rosseneu, M. & Brasseur, R. (1997). The 118-135 peptide of the human prion protein forms amyloid fibrils and induces liposome fusion. J. Mol. Biol. 274, 381-393.
46. Podbilewicz, B. (1996). ADM-1, a protein with metalloprotease- and disintegrin-like domains, is expressed in syncytial organs, sperm, and sheath cells of sensory organs in Caenorhabditis elegans. Mol. Biol. Cell 7, 1877-1893.
47. Primakoff, P., Hyatt, H. & Tredick-Kline, J. (1987). Identification and purification of a sperm surface protein with a potential role in sperm-egg membrane fusion. J. Cell Biol. 104, 141-149.
48. Rafalski, M., Lear, J. D. & Degrado, W. F. (1990). Phospholipid interactions of synthetic peptides representing the N-terminus of HIV gp41. Biochemistry 29, 7917-7922.
49. Rahman, M. & Brasseur, R. (1994). WinMGM: A fast CPK molecular graphics program for analyzing molecular structure. J. Mol. Graphics 12, 212-219.
50. Rahman, M., Lins, L., Thomas-Soumarmon, A. & Brasseur, R. (1997). Are amphipathic asymmetric peptides ubiquitous structures for membrane destabilisation? J. Mol. Model 3, 203-215.
51. Rodriguez-Crespo, I., Nunez, E., Gomez-Gutierrez, J., Yelamos, B., Albar, J. P., Peterson, D. L. & Gavilanes, F. (1995). Phospholipid interaction of the putative fusion peptide of hepatitis B virus surface antigen S protein. J. Gen. Virol. 76, 301-308.
52. Rodriguez-Crespo, I., Gomez-Gutierrez, J., Encinar, J. A., Gonzalez-Ros, J. M., Albar, J. P., Peterson, D. L. & Gavilanes, F. (1996). Structural properties of the putative fusion peptide of hepatitis B virus upon interaction with phospholipids. Circular dichroism and Fourier-transform infrared spectroscopy studies. Eur. J. Biochem. 242, 243-248.
53. Ruiz-Arguello, M. B., Goni, F. M., Pereira, F. B. & Nieva, J. L. (1998). Phosphatidylinositol-dependent membrane fusion induced by a putative fusogenic sequence of Ebola virus. J. Virol. 72(3), 1775-1781.
54. Schanck, A., Brasseur, R. & Peuvot, J. (1998). Destabilization of a model membrane by a predicted fusion peptide of fertilin α. J. Chim. Phys. 95, 467-473.
55. Siegel, D. P. (1993). Energetics of intermediates in membrane fusion: Comparison of stalk and inverted micellar intermediate mechanisms. Biophys. J. 65, 2124-2140.
56. Talmud, P., Lins, L. & Brasseur, R. (1996). Prediction of signal peptide functional properties: A study of the orientation and angle of insertion of yeast invertase mutants and human apolipoprotein B signal peptide variants. Protein Eng. 9, 317-321.
57. Tatulian, S. A., Hinterdorfer, P., Baber, G. & Tamm, L. K. (1995). Influenza hemagglutinin assumes a tilted conformation during membrane fusion as determined by attenuated total reflection FTIR spectroscopy. EMBO J. 14, 5514-5523.
58. Uren, A. G. & Vaux, D. L. (1996). Molecular and clinical aspects of apoptosis. Pharmacol. Ther. 72, 37-50.
59. Vonèche, V., Portetelle, D., Kettmann, R., Willems, L., Limbach, K., Paoletti, E., Ruysschaert, J. M., Burny, A. & Brasseur, R. (1992). Fusogenic segments of bovine leukemia virus and simian immunodeficiency virus are interchangeable and mediate fusion by means of oblique insertion in the lipid bilayer of their target cells. Proc. Nat. Acad. Sci. U.S.A. 89, 3810-3814.
60. Wolfsberg, T. G., Bazan, J. F., Blobel, C. P., Myles, D. G., Primakoff, P. & White, J. M. (1993). The precursor region of a protein active in sperm-egg fusion contains a metalloprotease and a disintegrin domain: Structural, functional, and evolutionary implications. Proc. Nat. Acad. Sci. U.S.A. 90, 10783-10787.
61. Wolfsberg, T. G., Straight, P. D., Gerena, R. L., Huovila, A-P. J., Primakoff, P., Myles, D. G. & White, J. M. (1995). ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with A Disintegrin And Metalloprotease domain. Develop. Biol. 169, 378-383.
62. Yagami-Hiromasa, T., Sato, T., Kurisaki, T., Kamijo, K., Nabeshima, Y. I. & Fujisawa-Sehara, A. (1995). A metalloprotease-disintegrin participating in myoblast fusion. Nature 377, 652-656.
63. Yeagle, P. L., Epand, R. M., Richardson, C. D. & Flanagan, T. D. (1991). Effects of the "fusion peptide" from measles virus on the structure of N-methyl dioleoylphosphatidylethanolamine membranes and their fusion with Sendai virus. Biochim. Biophys. Acta 1065, 49-53.
64. Yoneda, J., Saiki, I., Igarashi, Y., Kobayashi, H., Fujii, H., Ishizaki, Y., Kimizuka, F., Kato, I. & Azuma, I. (1995). Role of the heparin-binding domain of chimeric peptides derived from fibronectin in cell spreading and motility. Exp. Cell. Res. 217, 169-179.