SCOPUS 정보 검색 플랫폼

Volumn 409, Issue 1, 2003, Pages 127-133

Functional analysis of the molecular determinants of cyclooxygenase-2 acetylation by 2-acetoxyphenylhept-2-ynyl sulfide

(5) Hochgesang Jr , G Phillip a Nemeth Cawley, Jennifer F a Rowlinson, Scott W a Caprioli, Richard M a Marnett, Lawrence J a

a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE (United States)

Author keywords

Acetoxyphenylheptynyl sulfide; Acetylation; Cyclooxygenase; Mass spectrometry; Site directed mutagenesis

Indexed keywords

2 ACETOXYPHENYLHEPT 2 YNYLSULFIDE; ACETIC ACID DERIVATIVE; ACETYLSALICYLIC ACID; ARGININE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; HETEROCYCLIC COMPOUND; PHENYLALANINE; SERINE; TYROSINE; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROGEN BOND; MASS SPECTROMETRY; MUTATION; NONHUMAN; PRIORITY JOURNAL; REDUCTION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BINDING SITES; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYANOGEN BROMIDE; CYCLOOXYGENASE 2; ENZYME INHIBITORS; HEPTANES; HYDROGEN; HYDROGEN BONDING; INSECTS; ISOENZYMES; LIGANDS; MASS SPECTROMETRY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN CONFORMATION; SERINE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SULFIDES; TYROSINE;

EID: 0037226126 PISSN: 00039861 EISSN: None Source Type: Journal
DOI: 10.1016/S0003-9861(02)00549-0 Document Type: Article

Times cited : (6)

References (28)

1
- 0031777185
- J.R. Vane, Y.S. Bakhle, R.M. Botting, Annu. Rev. Pharmacol. Toxicol. 38 (1998) 97-120.
- (1998) Annu. Rev. Pharmacol. Toxicol. , vol.38 , pp. 97-120
- Vane, J.R.¹ Bakhle, Y.S.² Botting, R.M.³

2
- 0014217467
- M. Hamberg, B. Samuelsson, J. Biol. Chem. 242 (1967) 5336-5343.
- (1967) J. Biol. Chem. , vol.242 , pp. 5336-5343
- Hamberg, M.¹ Samuelsson, B.²

3
- 0017070560
- T. Miyamoto, N. Ogino, S. Yamamoto, O. Hayaishi, J. Biol. Chem. 251 (1976) 2629-2636.
- (1976) J. Biol. Chem. , vol.251 , pp. 2629-2636
- Miyamoto, T.¹ Ogino, N.² Yamamoto, S.³ Hayaishi, O.⁴

4
- 0026702494
- B.S. Fletcher, D.A. Kujubu, D.M. Perrin, H.R. Herschman, J. Biol. Chem. 267 (1992) 4338-4344.
- (1992) J. Biol. Chem. , vol.267 , pp. 4338-4344
- Fletcher, B.S.¹ Kujubu, D.A.² Perrin, D.M.³ Herschman, H.R.⁴

5
- 0025857560
- D.L. DeWitt, Biochim. Biophys. Acta Lipids Lipid Metab. 1083 (1991) 121-134.
- (1991) Biochim. Biophys. Acta Lipids Lipid Metab. , vol.1083 , pp. 121-134
- DeWitt, D.L.¹

6
- 0030049390
- H.R. Herschman, Biochim. Biophys. Acta Lipids Lipid Metab. 1299 (1996) 125-140.
- (1996) Biochim. Biophys. Acta Lipids Lipid Metab. , vol.1299 , pp. 125-140
- Herschman, H.R.¹

7
- 0031689543
- R.N. DuBois, S.B. Abramson, L. Cro2ord, R.A. Gupta, L.S. Simon, B.A. Van de Putte, P.E. Lipsky, FASEB J. 12 (1998) 1063-1073.
- (1998) FASEB J. , vol.12 , pp. 1063-1073
- DuBois, R.N.¹ Abramson, S.B.² Crofford, L.³ Gupta, R.A.⁴ Simon, L.S.⁵ Van de Putte, B.A.⁶ Lipsky, P.E.⁷

8
- 13444266910
- T.D. Penning, J.J. Talley, S.R. Bertenshaw, J.S. Carter, P.W. Collins, S. Docter, M.J. Graneto, L.F. Lee, J.W. Malecha, J.M. Miyashiro, R.S. Rogers, D.J. Rogier, S.S. Yu, G.D. Anderson, E.G. Burton, J.N. Cogburn, S.A. Gregory, C.M. Kobolt, W.E. Perkins, K. Siebert, A.W. Veenhuizen, Y.Y. Zhang, P.C. Isakson, J. Med. Chem. 40 (1997) 1347-1365.
- (1997) J. Med. Chem. , vol.40 , pp. 1347-1365
- Penning, T.D.¹ Talley, J.J.² Bertenshaw, S.R.³ Carter, J.S.⁴ Collins, P.W.⁵ Docter, S.⁶ Graneto, M.J.⁷ Lee, L.F.⁸ Malecha, J.W.⁹ Miyashiro, J.M.¹⁰ Rogers, R.S.¹¹ Rogier, D.J.¹² Yu, S.S.¹³ Anderson, G.D.¹⁴ Burton, E.G.¹⁵ Cogburn, J.N.¹⁶ Gregory, S.A.¹⁷ Kobolt, C.M.¹⁸ Perkins, W.E.¹⁹ Siebert, K.²⁰ more..

9
- 0033526928
- P. Prasit, Z. Wang, C. Brideau, C.C. Chan, S. Charleson, W. Cromlish, D. Ethier, J.F. Evans, A.W. Ford-Hutchinson, J.Y. Gauthier, R. Gordon, J. Guay, M. Gresser, S. Kargman, B. Kennedy, Y. Leblanc, S. Léger, J. Mancini, G.P. O'Neill, M. Ouellet, M.D. Percival, H. Perrier, D. Riendeau, I. Rodger, Bioorg. Med. Chem. Lett. 9 (1999) 1773-1778.
- (1999) Bioorg. Med. Chem. Lett. , vol.9 , pp. 1773-1778
- Prasit, P.¹ Wang, Z.² Brideau, C.³ Chan, C.C.⁴ Charleson, S.⁵ Cromlish, W.⁶ Ethier, D.⁷ Evans, J.F.⁸ Ford-Hutchinson, A.W.⁹ Gauthier, J.Y.¹⁰ Gordon, R.¹¹ Guay, J.¹² Gresser, M.¹³ Kargman, S.¹⁴ Kennedy, B.¹⁵ Leblanc, Y.¹⁶ Léger, S.¹⁷ Mancini, J.¹⁸ O'Neill, G.P.¹⁹ Ouellet, M.²⁰ more..

10
- 0034624748
- J.J. Talley, D.L. Brown, J.S. Carter, M.J. Graneto, C.M. Koboldt, J.L. Masferrer, W.E. Perkins, R.S. Rogers, A.F. Shaffer, Y.Y. Zhang, B.S. Zweifel, K. Seibert, J. Med. Chem. 43 (2000) 775-777.
- (2000) J. Med. Chem. , vol.43 , pp. 775-777
- Talley, J.J.¹ Brown, D.L.² Carter, J.S.³ Graneto, M.J.⁴ Koboldt, C.M.⁵ Masferrer, J.L.⁶ Perkins, W.E.⁷ Rogers, R.S.⁸ Shaffer, A.F.⁹ Zhang, Y.Y.¹⁰ Zweifel, B.S.¹¹ Seibert, K.¹²

11
- 0034644396
- F.E. Silverstein, G. Faich, J.L. Goldstein, L.S. Simon, T. Pincus, A. Whelton, R. Makuch, G. Eisen, N.M. Agrawal, W.F. Stenson, A.M. Burr, W.W. Zhao, J.D. Kent, J.B. Lefkowith, K.M. Verburg, G.S. Geis, JAMA 284 (2000) 1247-1255.
- (2000) JAMA , vol.284 , pp. 1247-1255
- Silverstein, F.E.¹ Faich, G.² Goldstein, J.L.³ Simon, L.S.⁴ Pincus, T.⁵ Whelton, A.⁶ Makuch, R.⁷ Eisen, G.⁸ Agrawal, N.M.⁹ Stenson, W.F.¹⁰ Burr, A.M.¹¹ Zhao, W.W.¹² Kent, J.D.¹³ Lefkowith, J.B.¹⁴ Verburg, K.M.¹⁵ Geis, G.S.¹⁶

12
- 0034707105
- 2 p following 1528
- C. Bombardier, L. Laine, A. Reicin, D. Shapiro, R. Burgos-Vargas, B. Davis, R. Day, M.B. Ferraz, C.J. Hawkey, M.C. Hochberg, T.K. Kvien, T.J. Schnitzer, N. Engl. J Med. 343 (2000) 1520-1528, 2 p following 1528.
- (2000) N. Engl. J Med. , vol.343 , pp. 1520-1528
- Bombardier, C.¹ Laine, L.² Reicin, A.³ Shapiro, D.⁴ Burgos-Vargas, R.⁵ Davis, B.⁶ Day, R.⁷ Ferraz, M.B.⁸ Hawkey, C.J.⁹ Hochberg, M.C.¹⁰ Kvien, T.K.¹¹ Schnitzer, T.J.¹²

13
- 0032557710
- A.S. Kalgutkar, B.C. Crews, S.W. Rowlinson, C. Garner, K. Seibert, L.J. Marnett, Science 280 (1998) 1268-1270.
- (1998) Science , vol.280 , pp. 1268-1270
- Kalgutkar, A.S.¹ Crews, B.C.² Rowlinson, S.W.³ Garner, C.⁴ Seibert, K.⁵ Marnett, L.J.⁶

14
- 0032548140
- A.S. Kalgutkar, K.R. Kozak, B.C. Crews, G.P. Hochgesang Jr., L.J. Marnett, J. Med. Chem. 41 (1998) 4800-4818.
- (1998) J. Med. Chem. , vol.41 , pp. 4800-4818
- Kalgutkar, A.S.¹ Kozak, K.R.² Crews, B.C.³ Hochgesang G.P., Jr.⁴ Marnett, L.J.⁵

15
- 0019186365
- F.J. Van Der Ouderaa, M. Buytenhek, D.H. Nugteren, D.A. Van Dorp, Eur. J. Biochem. 109 (1980) 1-8.
- (1980) Eur. J. Biochem. , vol.109 , pp. 1-8
- Van Der Ouderaa, F.J.¹ Buytenhek, M.² Nugteren, D.H.³ Van Dorp, D.A.⁴

16
- 0025248570
- D.L. DeWitt, E.A. El-Harith, S.A. Kraemer, M.J. Andrews, E.F. Yao, R.L. Armstrong, W.L. Smith, J. Biol. Chem. 265 (1990) 5192-5198.
- (1990) J. Biol. Chem. , vol.265 , pp. 5192-5198
- DeWitt, D.L.¹ El-Harith, E.A.² Kraemer, S.A.³ Andrews, M.J.⁴ Yao, E.F.⁵ Armstrong, R.L.⁶ Smith, W.L.⁷

17
- 0029056992
- P.J. Loll, D. Picot, R.M. Garavito, Nat. Struct. Biol. 2 (1995) 637-642.
- (1995) Nat. Struct. Biol. , vol.2 , pp. 637-642
- Loll, P.J.¹ Picot, D.² Garavito, R.M.³

18
- 0033551732
- S.W. Rowlinson, B.C. Crews, C.A. Lanzo, L.J. Marnett, J. Biol. Chem. 274 (1999) 23305-23310.
- (1999) J. Biol. Chem. , vol.274 , pp. 23305-23310
- Rowlinson, S.W.¹ Crews, B.C.² Lanzo, C.A.³ Marnett, L.J.⁴

19
- 0035852985
- J.F. Nemeth, G.P.J. Hochgesang, L.J. Marnett, R.M. Caprioli, G.P. Hochensang Jr., Biochemistry 40 (2001) 3109-3116.
- (2001) Biochemistry , vol.40 , pp. 3109-3116
- Nemeth, J.F.¹ Hochgesang, G.P.J.² Marnett, L.J.³ Caprioli, R.M.⁴ Hochensang G.P., Jr.⁵

20
- 12944309750
- G.P. Hochgesang, L.J. Marnett, J. Am. Chem. Soc. 122 (2000) 6514-6515.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 6514-6515
- Hochgesang, G.P.¹ Marnett, L.J.²

21
- 0033546297
- C.J. Rieke, A.M. Mulichak, R.M. Garavito, W.L. Smith, J. Biol. Chem. 274 (1999) 17109-17114.
- (1999) J. Biol. Chem. , vol.274 , pp. 17109-17114
- Rieke, C.J.¹ Mulichak, A.M.² Garavito, R.M.³ Smith, W.L.⁴

22
- 0028783912
- J.A. Mancini, D. Riendeau, J.-P. Falgueyret, P.J. Vickers, G.P. O'Neill, J. Biol. Chem. 270 (1995) 29372-29377.
- (1995) J. Biol. Chem. , vol.270 , pp. 29372-29377
- Mancini, J.A.¹ Riendeau, D.² Falgueyret, J.-P.³ Vickers, P.J.⁴ O'Neill, G.P.⁵

23
- 0035339905
- B.S. Selinsky, K. Gupta, C.T. Sharkey, P.J. Loll, Biochemistry 40 (2001) 5172-5180.
- (2001) Biochemistry , vol.40 , pp. 5172-5180
- Selinsky, B.S.¹ Gupta, K.² Sharkey, C.T.³ Loll, P.J.⁴

24
- 0030461132
- R.G. Kurumbail, A.M. Stevens, J.K. Gierse, J.J. McDonald, R.A. Stegeman, J.Y. Pak, D. Gildehaus, J.M. Miyashiro, T.D. Penning, K. Seibert, P.C. Isakson, W.C. Stallings, Nature 384(1996) 644-648.
- (1996) Nature , vol.384 , pp. 644-648
- Kurumbail, R.G.¹ Stevens, A.M.² Gierse, J.K.³ McDonald, J.J.⁴ Stegeman, R.A.⁵ Pak, J.Y.⁶ Gildehaus, D.⁷ Miyashiro, J.M.⁸ Penning, T.D.⁹ Seibert, K.¹⁰ Isakson, P.C.¹¹ Stallings, W.C.¹²

25
- 0029911267
- C. Luong, A. Miller, J. Barnett, J. Chow, C. Ramesha, M.F. Browner, Nat. Struct. Biol. 3 (1996) 927-933.
- (1996) Nat. Struct. Biol. , vol.3 , pp. 927-933
- Luong, C.¹ Miller, A.² Barnett, J.³ Chow, J.⁴ Ramesha, C.⁵ Browner, M.F.⁶

26
- 0034665857
- M.G. Malkowski, S.L. Ginell, W.L. Smith, R.M. Garavito, Science 289 (2000) 1933-1937.
- (2000) Science , vol.289 , pp. 1933-1937
- Malkowski, M.G.¹ Ginell, S.L.² Smith, W.L.³ Garavito, R.M.⁴

27
- 0035813182
- M.G. Malkowski, E.D. Thuresson, K.M. Lakkides, C.J. Rieke, R. Micielli, W.L. Smith, R.M. Garavito, J. Biol. Chem. 276 (2001) 37547-37555.
- (2001) J. Biol. Chem. , vol.276 , pp. 37547-37555
- Malkowski, M.G.¹ Thuresson, E.D.² Lakkides, K.M.³ Rieke, C.J.⁴ Micielli, R.⁵ Smith, W.L.⁶ Garavito, R.M.⁷

28
- 0028009093
- D. Picot, P.J. Loll, R.M. Garavito, Nature 367 (1994) 243-249.
- (1994) Nature , vol.367 , pp. 243-249
- Picot, D.¹ Loll, P.J.² Garavito, R.M.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.