The N- and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription

Nucleic Acids Research

Volumn 29, Issue 6, 2001, Pages 1373-1380

  Tani, Shoichi ^a   Kurooka, Hisanori ^a   Aoki, Tomokazu ^a   Hashimoto, Nobuo ^a   Honjo, Tasuku ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; DNA; DNA BINDING PROTEIN; NOTCH RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; CONTROLLED STUDY; DNA SEQUENCE; GENE CONSTRUCT; GENE DISRUPTION; GENE LOCUS; GENE MUTATION; GENETIC TRANSCRIPTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION;

ANIMALIA;

EID: 0035869115     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/29.6.1373     Document Type: Article

References (35)

1. The shortest path from the surface to the nucleus: RBP-Jk/Su(H) transcription
2. Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)
3. The Drosophila homolog of the immunoglobulin recombination signal-binding protein regulates peripheral nervous system development
4. Suppressor of Hairless, the Drosophila homolog of the mouse recombination signal-binding protein gene, controls sensory organ cell fates
5. The suppressor of hairless protein participates in notch receptor signaling
6. An activated Notch suppresses neurogenesis and myogenesis by not gliogenesis in mammalian cells
7. δ-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis
8. Notch signalling controls pancreatic cell differentation
9. An activated form of Notch influences the choice between CD4 and CD8 T cell lineages
10. Disruption of the mouse RBP-JΚ gene results in early embryonic dealth
11. Signalling downstream of activated mammalian Notch
12. Nuclear access and action of notch in vivo
13. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
14. Epstein-Barr virus nuclear antigen 2 exerts its transactivating function interaction with recombination signal binding protein RBP-JΚ, the homologue of Drosphila Suppressor of Hairless
15. Mediation of Epstein-Barr virus EBNA2 transactivation by recombination signal-binding protein JΚ
16. Functional replacement of the intracellular region of the Notch1 receptor by Epstein-Barr virus nuclear antigen 2
17. The recombination signal sequence-binding protein RBP-2N function as a transcriptional repressor
18. Masking of the CBF1/RBPJΚ transcriptional repression domain by Epstein-Barr virus EBNA2
19. The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription
20. RBP-JΚ repression activity is mediated a co-repressor and antagonized by the Epstein-Barr virus transription factor EBNA2
21. A histone deacetylase corepressor complex regulates the Notch signal transduction pathway
22. CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
23. LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein
24. Truncated mammalian Notch1 activates CBF1/ RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2
25. Involvement of RBP-J in biological functions of mouse Notch1 and its derivative
26. Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-JΚ or nuclear localization sequences retain the ability to association with RBP-JΚ and activate transcription
27. The intracellular domain of mouse Notch: A constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD
28. Roles of the ankyrin repeats and C-terminal region of the mouse notch1 intracellular region
29. Biochemical and immunological characterization of the DNA binding protein (RBP-JΚ) to mouse JΚ recombination signal sequence
30. EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD223 promoter utilizes a common targeting intermediate, CBF1
31. RBP-L, a transcription factor related to RBP-JΚ
32. Studies on the cell-type specific expression of RBP-L, a RBP-J family member, by replacement insertion of β-galactosidase
33. Site-directed mutagenesis study on DNA binding regions of the mouse homologue of Suppressor of Hairless, RBP-JΚ
34. Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors
35. Functional interaction between the mouse Notch1 intracellular region and histone acetyltransferases PCAF and GCN5