Human MafG is a functional partner for p45 NF-E2 in activating globin gene expression

Blood

Volumn 89, Issue 11, 1997, Pages 3925-3935

  Blank, Volker ^a   Kim, Min J ^a   Andrews, Nancy C ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE ZIPPER PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHICKEN; DNA BINDING; ENHANCER REGION; ERYTHROPOIESIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; MAMMAL; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0030916735     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v89.11.3925     Document Type: Article

References (60)

1. Tuan D, Solomon W, Li Q, London IM: The "beta-like-globin" gene domain in human erythroid cells. Proc Natl Acad Sci USA 82:6384, 1985
2. Grosveld F, van Assendelft GB, Greaves DR, Kollias G: Position-independent, high-level expression of the human β-globin gene in transgenic mice. Cell 51:975, 1987
3. Andrews NC, Orkin SH: Transcriptional control of erythropoiesis. Curr Opin Hematol 1:119, 1994
4. Moi P, Kan YW: Synergistic enhancement of globin gene expression by activator protein-1-like proteins. Proc Natl Acad Sci USA 87:9000, 1990
5. Ney PA, Sorentino BP, Lowrey CH, Nienhuis AW: Inducibility of the HSII enhancer depends on binding of an erythroid specific nuclear protein. Nucleic Acids Res 18:6011, 1990
6. Talbot D, Philipsen S, Fraser P, Grosveld F: Detailed analysis of the site 3 region of the human β-globin dominant control region. EMBO J 9:2169, 1990
7. Moon AM, Ley TJ: Functional properties of the β-globin locus control region in K562 erythroleukemia cells. Blood 77:2272, 1991
8. Talbot D, Grosveld F: The 5′ HS2 of the globin locus control region enhances transcription through the interaction of a multimeric complex binding at two functionally distinct NF-E2 binding sites. EMBO J 10:1391, 1991
9. Pondel MD, George M, Proudfoot NJ: The LCR-like α-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation. Nucleic Acids Res 20:237, 1992
10. Caterina JJ, Donze D, Sun C-W, Ciavatta DJ, Townes TM: Cloning and functional characterization of LCR-F1: A bZIP transcription factor that activates erythroid-specific, human globin gene expression. Nucleic Acids Res 22:2383, 1994
11. Gong Q, McDowell JC, Dean A: Essential role of NF-E2 in remodeling of chromatin structure and transcriptional activation of the epsilon-globin gene in vivo by 5′ hypersensitive site 2 of the beta-globin locus control region. Mol Cell Biol 16:6055, 1996
12. Stamatoyannopoulos JA, Goodwin A, Joyce T, Lowrey CH: NF-E2 and GATA binding motifs are required for the formation of DNase I hypersensitive site 4 of the human β-globin locus control region. EMBO J 14:106, 1995
13. Armstrong JA, Emerson BM: NF-E2 disrupts chromatin structure at human beta-globin locus control region hypersensitive site 2 in vitro. Mol Cell Biol 16:5634, 1996
14. Boyes J, Felsenfeld G: Tissue-specific factors additively increase the probability of the all-or-none formation of a hypersensitive site. EMBO J 15:2496, 1996
15. Mignotte V, Wall L, deBoer E, Grosveld F, Romeo P-H: Two tissue-specific factors bind the erythroid promoter of the human porphobilinogen deaminase gene. Nucleic Acids Res 17:37, 1989
16. Andrews NC, Erdjument-Bromage H, Davidson MB, Tempst P, Orkin SH: Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein. Nature 362:722, 1993
17. Andrews NC, Kotkow KJ, Ney PA, Erdjument-Bromage H, Tempst P, Orkin SH: The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene. Proc Natl Acad Sci USA 90:11488, 1993
18. Ney PA, Andrews NC, Jane SM, Safer B, Purucker ME, Morton CC, Weremowicz S, Goff SC, Orkin SH, Nienhuis AW: Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol 13:5604, 1993
19. Peters LL, Andrews NC, Eicher EM, Davidson MB, Orkin SH, Lux SE: Mouse microcytic anaemia caused by a defect in the gene encoding the globin enhancer-binding protein NF-E2. Nature 362:768, 1993
20. Mohler J, Vani K, Leung S, Epstein A: Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis. Mech Develop 34:3, 1991
21. Bowerman B, Draper BW, Mello CC, Priess JR: The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos. Cell 74:443, 1993
22. Chan JY, Han X-L, Kan YW: Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. Proc Natl Acad Sci USA 90:11371, 1993
23. Luna L, Johnsen O, Skartlien AH, Pedeutour F, Turc-Carel C, Prydz H, Kolsto AB: Molecular cloning of a putative novel human bZIP transcription factor on chromosome 17q22. Genomics 22:553, 1994
24. Moi P, Chan K, Asunis I, Cao A, Kan YW: Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP-1 repeat of the β-globin locus control region. Proc Natl Acad Sci USA 91:9926, 1994
25. Chui DHK, Tang W, Orkin SH: cDNA cloning of murine Nrf2 gene, coding for a p45 NF-E2 related transcription factor. Biochem Biophys Res Commun 209:40, 1995
26. Itoh K, Igarashi K, Hayashi N, Nishizawa M, Yamamoto M: Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins. Mol Cell Biol 15:4184, 1995
27. Oyake T, Itoh K, Motohashi H, Hayashi N, Hoshino H, Nishizawa M, Yamamoto M, Igarashi K: Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with mafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16:6083, 1996
28. Kotkow KJ, Orkin SH: Dependence of globin gene expression in mouse erythroleukemia cells on the NF-E2 heterodimer. Mol Cell Biol 15:4640, 1995
29. Cheng X, Reginato MJ, Andrews NC, Lazar MA: The transcriptional integrator CBP mediates positive crosstalk between nuclear hormone receptors and the hematopoietic bZip protein p45/ NF-E2. Mol Cell Biol 17:1407, 1997
30. Fujiwara KT, Kataoka K, Nishizawa M: Two new members of the maf oncogene family, mafK and mafF, encode nuclear b-Zip proteins lacking putative trans-activator domain. Oncogene 8:2371, 1993
31. Igarashi K, Kataoka K, Itoh K, Hayashi N, Nishizawa M, Yamamoto M: Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367:568, 1994
32. Igarashi K, Itoh K, Motohashi H, Hayashi N, Matuzaki Y, Nakauchi H, Nishizawa M, Yamamoto M: Activity and expression of murine small maf family protein mafK. J Biol Chem 270:7615, 1995
33. Nishizawa M, Kataoka K, Goto N, Fujiwara KT, Kawai S: v-maf, a viral oncogene that encodes a "leucine zipper" motif. Proc Natl Acad Sci USA 86:7711, 1989
34. Swaroop A, Xu J, Pawar H, Jackson A, Skolnick C, Agarwal N: A conserved retina-specific gene encodes a basic motif/leucine zipper domain. Proc Natl Acad Sci USA 89:266, 1992
35. Cordes SP, Barsh GS: The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell 79:1025, 1994
36. Kataoka K, Fujiwara KT, Noda M, Nishizawa M: MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun. Mol Cell Biol 14:7581, 1994
37. Ho I-C, Hodge MR, Rooney JW, Glimcher LH: The protooncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973, 1996
38. Pouponnot C, Nishizawa M, Calothy G, Pierani A: Transcriptional stimulation of the retina-specific QR1 gene upon growth arrest involves a maf-related protein. Mol Cell Biol 15:5563, 1995
39. Rehemtulla A, Warwar R, Kumar R, Ji X, Zack DJ: The basic motif-leucine zipper transcription factor Nrl can positively regulate rhodopsin gene expression. Proc Natl Acad Sci USA 93:191, 1996
40. Sieweke MH, Tekotte H, Frampton J, Graf T: MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation. Cell 85:49, 1996
41. Kataoka K, Igarashi K, Itoh K, Fujiwara KT, Noda M, Yamamoto M, Nishizawa M: Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Mol Cell Biol 15:2180, 1995
42. Igarashi K, Itoh K, Hayashi N, Nishizawa M, Yamamoto M: Conditional expression of the ubiquitous transcription factor mafK induces erythroleukemia cell differentiation. Proc Natl Acad Sci USA 92:7445, 1995
43. Lu SJ, Rowan S, Bani MR, Ben-David Y: Retroviral integration within the Fli-2 locus results in inactivation of the erythroid transcription factor NF-E2 in Friend erythroleukemias: Evidence that NF-E2 is essential for globin expression. Proc Natl Acad Sci USA 91:8398, 1994
44. Johnsen O, Skammelsrud N, Luna L, Nishizawa M, Prydz H, Kolsto A-B: Small maf proteins interact with the human transcription factor TCF11/Nrf1/LCR-F1. Nucleic Acids Res 24:4289, 1996
45. Kotkow KJ, Orkin SH: Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus. Proc Natl Acad Sci USA 93:3514, 1996
46. Reynolds DS, Serafin WE, Faller DV, Wall DA, Abbas AK, Dvorak AM, Austen KF, Stevens RL: Immortalization of murine connective tissue-type mast cells at multiple stages of their differentiation by coculture of splenocytes with fibroblasts that produce Kirsten sarcoma virus. J Biol Chem 263:12783, 1988
47. Greenberg SM, Rosenthal DS, Greeley TA, Tantravahi R, Handin RI: Characterization of a new megakaryocytic cell line: The Dami cell. Blood 72:1968, 1988
48. Sudo K, Chinen K, Nakamura Y: 2058 expressed sequence tags (ESTs) from a human fetal lung cDNA library. Genomics 24:276, 1994
49. Neuhold LA, Wold B: HLH forced dimers: Tethering MyoD to E47 generates a dominant positive myogenic factor insulated from negative regulation by Id. Cell 74:1033, 1993
50. Mizushima S, Nagata S: pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res 18:5322, 1990
51. Strauss EC, Andrews NC, Higgs DR, Orkin SH: In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction. Mol Cell Biol 12:2135, 1992
52. Andrews NC, Faller DV: A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res 19:2499, 1991
53. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual (ed 2). Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1989
54. Baron MH, Maniatis T: Rapid reprogramming of globin gene expression in transient heterokaryons. Cell 46:591, 1986
55. Shaw G, Kamen R: A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659, 1986
56. Lee NH, Weinstock KG, Kirkness EF, Earle-Hughes JA, Fuldner RA, Marmaras S, Glodek A, Gocayne JD, Adams MD, Kerlavage AR, Fraser CM, Ventner JC: Comparative expressed sequence tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment. Proc Natl Acad Sci USA 92:8303, 1995
57. Toki T, Itoh J, Arai K, Kitazawa J, Yokoyama M, Igarahi K, Yamamoto M, Ito E: Abundant expression of erythroid transcription factor p45 NF-E2 mRNA in human peripheral granulocytes. Biochem Biophys Res Commun 219:760, 1996
58. Ney PA, Sorrentino BP, McDonagh KT, Nienhuis AW: Tandem AP-1 binding sites within the human β-globin dominant control region function as an inducible enhancer in erythroid cells. Genes Develop 4:993, 1990
59. Lowrey CH, Bodine DM, Nienhuis AW: Mechanism of DNase I hypersensitive site formation within the human globin locus control region. Proc Natl Acad Sci USA 89:1143, 1992
60. Kerppola TK, Curran T: A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family members. Oncogene 9:3149, 1994