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Volumn 67, Issue 17, 2002, Pages 5938-5945

Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. Characterization of an unusual acetal byproduct

(4) Yoshimura, Yuichi a Moon, Hyung R a Choi, Yongseok a Marquez, Victor E a

a NATIONAL CANCER INSTITUTE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RACEMIC MIXTURES;

ACETYLATION; BYPRODUCTS; CATALYSIS; CONFORMATIONS; HYDROLYSIS; OLEFINS; SYNTHESIS (CHEMICAL);

ORGANIC COMPOUNDS;

[2 ACETOXY 4 (2,2, DIMETHYL 1,2 DIPHENYL 1 SILAPROPOXY)BICYCLO[3.1.0]HEXYL]METHYL ACETATE; [4 (2,2 DIMETHYL 1,1 DIPHENYL 1 SILAPROPOXY) 2 HYDROXYBICYCLO[3.1.0]HEXYL]METHYL ACETATE; ACETAL; ACETALDEHYDE; ADENOSINE DEAMINASE; BICYCLO COMPOUND; NUCLEOSIDE DERIVATIVE; PYRIMIDINE DERIVATIVE; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ACETAL DERIVATIVE; BICYCLO(3.1.0)HEXANE; NUCLEOSIDE;

ACETYLATION; ARTICLE; CATALYSIS; CATALYST; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; ENANTIOSELECTIVITY; REACTION ANALYSIS; STRUCTURE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC CHEMISTRY; STEREOISOMERISM; SYNTHESIS;

ACETALS; ACETYLATION; BICYCLO COMPOUNDS; CATALYSIS; CHEMISTRY, ORGANIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIZATION; LIPASE; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NUCLEOSIDES; STEREOISOMERISM;

EID: 0037162655 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo020249u Document Type: Article

Times cited : (34)

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