Carbocyclic analogues of the potent cytidine deaminase inhibitor 1-(β- D-ribofuranosyl)-1,2-dihydropyrimidin-2-one (zebularine)

Journal of Medicinal Chemistry

Volumn 41, Issue 14, 1998, Pages 2572-2578

  Jeong, Lak Shin ^a,c   Buenger, Greg ^a,d   McCormack, John J ^b   Cooney, David A ^a   Hao, Zhang ^a,e   Marquez, Victor E ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF VERMONT   (United States)

^c Ewha Womans University   (South Korea)

^d Flint AG   (Switzerland)

^e CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (HYDROXYMETHYL) 2,3 DIHYDROXY 4 [PYRIMIDIN 2(1H) ON 1 YL]BICYCLO[3.1.0]HEXANE; ARISTEROMYCIN; CYTIDINE DEAMINASE; CYTIDINE DEAMINASE INHIBITOR; NEPLANOCIN A; UNCLASSIFIED DRUG; ZEBULARINE;

ARTICLE; DRUG MECHANISM; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; HUMAN; MOUSE; NONHUMAN;

ANIMALS; CYTIDINE; CYTIDINE DEAMINASE; ENZYME INHIBITORS; HUMANS; MICE; PYRIMIDINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0000264435     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980111x     Document Type: Article

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