Conformationally locked carbocyclic nucleosides built on a bicyclo[3.1.0]hexane template with a fixed Southern conformation. Synthesis and antiviral activity

Journal of the Chemical Society - Perkin Transactions 1

Volumn , Issue 7, 1997, Pages 1073-1078

  Ezzitouni, Abdallah ^a   Marquez, Victor E ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748590516     PISSN: 0300922X     EISSN: None     Source Type: Journal    
DOI: 10.1039/a604352f     Document Type: Article

References (14)

1. The concept of pseudorotation was introduced and applied for the first time to substituted furanoses by C. Altona and M. Sundaralingam, J. Am. Chem. Soc., 1972, 94, 8205.
2. V. E. Marquez, M. A. Siddiqui, A. Ezzitouni, P. Russ, J. Wang, R. W. Wagner and M. D. Matteucci, J. Med. Chem., 1996, 39, 3739.
3. K.-H. Altmann, R. Kesselring, E. Francotte and G. Rihs, Tetrahedron Lett., 1994, 35, 2331.
4. C. K.-H. Tseng, NIAID, NIH, personal communication.
5. M. A. Siddiqui, H. Ford, Jr, C. George and V. E. Marquez, Nucleosides Nucleotides, 1996, 15, 235.
6. K.-H. Altmann, R. Imwinkelried, R. Kesselring and G. Rih, Tetrahedron Lett., 1994, 35, 7625.
7. A. Ezzitouni, J. J. Barchi, Jr and V. E. Marquez, J. Chem. Soc., Chem. Commun., 1995, 1345.
8. K. Biggadike, A. D. Borthwick, A. M. Exall, B. E. Kirk, S. M. Roberts, P. Youds, A. M. Z. Slawin and D. J. Williams, J. Chem. Soc., Chem. Commun., 1987, 255.
9. K. Biggadike, A. D. Borthwick, D. Evans, A. M. Exall, B. E. Kirk, S. M. Roberts, L. Stephenson and P. Youds, J. Chem. Soc., Perkin Trans. 1, 1988, 549.
10. R. Okazaki, J. Niwa and S. Kato, Bull. Chem. Soc. Jpn., 1988, 61, 1619.
11. T. Shiori, K. Ninomiya and S. Yamada, J. Am. Chem. Soc., 1972, 94, 6203.
12. T. F. Shealy and C. A. O'Dell, J. Heterocycl. Chem., 1976, 13, 1015.
13. K. Divakar and C. B. Reese, J. Chem. Soc., Perkin Trans. 1, 1982, 1171.
14. M. R. Harnden, P. G. Wyatt, M. R. Boyd and D. J. Sutton, J. Med. Chem., 1990, 33, 187.