메뉴 건너뛰기




Volumn 25, Issue 3, 1998, Pages 346-361

Redux signals and NF-κb activation in T cells

Author keywords

Free radicals; Glutathione; I B; NF B; Reactive oxygen species; Redox regulation; Transcription factors

Indexed keywords

GLUTATHIONE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR PROTEIN; REACTIVE OXYGEN METABOLITE; DNA;

EID: 0031595201     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(98)00067-7     Document Type: Review
Times cited : (202)

References (179)
  • 1
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes P. J., Karin M. Nuclear factor-kappaB a pivotal transcription factor in chronic inflammatory diseases . N. Engl. J. Med. 336:1997;1066-1071.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 2
    • 0027193894 scopus 로고
    • Endothelial nuclear factor-kappaB and the initiation of the atherosclerotic lesion
    • Collins T. Endothelial nuclear factor-kappaB and the initiation of the atherosclerotic lesion. Lab. Invest. 68:1993;499-508.
    • (1993) Lab. Invest. , vol.68 , pp. 499-508
    • Collins, T.1
  • 4
    • 0029091013 scopus 로고
    • Selective inhibition of E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 expression by inhibitors of I kappa B-alpha phosphorylation
    • Chen C. C., Rosenbloom C. L., Anderson D. C., Manning A. M. Selective inhibition of E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 expression by inhibitors of I kappa B-alpha phosphorylation. J. Immunol. 155:1995;3538-3545.
    • (1995) J. Immunol. , vol.155 , pp. 3538-3545
    • Chen, C.C.1    Rosenbloom, C.L.2    Anderson, D.C.3    Manning, A.M.4
  • 5
    • 0028047925 scopus 로고
    • Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice
    • Liao F., Andalibi A., Qiao J. H., Allayee H., Fogelman A. M., Lusis A. J. Genetic evidence for a common pathway mediating oxidative stress, inflammatory gene induction, and aortic fatty streak formation in mice. J. Clin. Invest. 94:1994;877-884.
    • (1994) J. Clin. Invest. , vol.94 , pp. 877-884
    • Liao, F.1    Andalibi, A.2    Qiao, J.H.3    Allayee, H.4    Fogelman, A.M.5    Lusis, A.J.6
  • 6
    • 0029664882 scopus 로고    scopus 로고
    • Induction and regulation of NFkappaB during aging: Role of protein kinases
    • Trebilcock G. U., Ponnappan U. Induction and regulation of NFkappaB during aging role of protein kinases . Clin. Immunol. Immunopathol. 79:1996;87-91.
    • (1996) Clin. Immunol. Immunopathol. , vol.79 , pp. 87-91
    • Trebilcock, G.U.1    Ponnappan, U.2
  • 7
    • 0029900649 scopus 로고    scopus 로고
    • Evidence for lowered induction of nuclear factor kappa B in activated human T lymphocytes during aging
    • Trebilcock G. U., Ponnappan U. Evidence for lowered induction of nuclear factor kappa B in activated human T lymphocytes during aging. Gerontology. 42:1996;137-146.
    • (1996) Gerontology , vol.42 , pp. 137-146
    • Trebilcock, G.U.1    Ponnappan, U.2
  • 8
    • 0023176085 scopus 로고
    • An inducible transcription factor activates expression of human immunodeficiency virus in T cells
    • Nabel G., Baltimore D. An inducible transcription factor activates expression of human immunodeficiency virus in T cells. Nature. 326:1987;711-713.
    • (1987) Nature , vol.326 , pp. 711-713
    • Nabel, G.1    Baltimore, D.2
  • 9
    • 0343755626 scopus 로고
    • Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro
    • Kawakami K., Scheidereit C., Roeder R. G. Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro. Proc. Natl. Acad. Sci. USA. 85:1988;4700-4704.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4700-4704
    • Kawakami, K.1    Scheidereit, C.2    Roeder, R.G.3
  • 10
    • 0024276882 scopus 로고
    • The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV
    • Bohnlein E., Lowenthal J. W., Siekevitz M., Ballard D. W., Franza B. R., Greene W. C. The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV. Cell. 53:1988;827-836.
    • (1988) Cell , vol.53 , pp. 827-836
    • Bohnlein, E.1    Lowenthal, J.W.2    Siekevitz, M.3    Ballard, D.W.4    Franza, B.R.5    Greene, W.C.6
  • 11
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1
    • Schreck R., Rieber P., Baeuerle P. A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. EMBO J. 10:1991;2247-2258.
    • (1991) EMBO J. , vol.10 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 12
    • 0028174061 scopus 로고
    • Function and activation of NF-kappa B in the immune system
    • Baeuerle P. A., Henkel T. Function and activation of NF-kappa B in the immune system. Ann. Rev. Immunol. 12:1994;141-179.
    • (1994) Ann. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkel, T.2
  • 13
    • 0026467248 scopus 로고
    • Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines
    • Israel N., Gougerot-Pocidalo M. A., Aillet F., Virelizier J. L. Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines. J. Immunol. 149:1992;3386-3393.
    • (1992) J. Immunol. , vol.149 , pp. 3386-3393
    • Israel, N.1    Gougerot-Pocidalo, M.A.2    Aillet, F.3    Virelizier, J.L.4
  • 14
    • 0025677250 scopus 로고
    • Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus
    • Staal F. J., Roederer M., Herzenberg L. A. Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA. 87:1990;9943-9947.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9943-9947
    • Staal, F.J.1    Roederer, M.2    Herzenberg, L.A.3
  • 17
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and I kappa B proteins: New discoveries and insights
    • Baldwin A. S. Jr. The NF-kappa B and I kappa B proteins new discoveries and insights . Ann. Rev. Immunol. 14:1996;649-683.
    • (1996) Ann. Rev. Immunol. , vol.14 , pp. 649-683
    • Baldwin A.S., Jr.1
  • 18
    • 0030747128 scopus 로고    scopus 로고
    • NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules
    • Baeuerle P. A., Baichwal V. R. NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules. Adv. Immunol. 65:1997;111-137.
    • (1997) Adv. Immunol. , vol.65 , pp. 111-137
    • Baeuerle, P.A.1    Baichwal, V.R.2
  • 19
    • 0028985037 scopus 로고
    • NF-kappa B and rel proteins in innate immunity
    • Kopp E. B., Ghosh S. NF-kappa B and rel proteins in innate immunity. Adv. Immunol. 58:1995;1-27.
    • (1995) Adv. Immunol. , vol.58 , pp. 1-27
    • Kopp, E.B.1    Ghosh, S.2
  • 20
    • 0028308257 scopus 로고
    • Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6
    • Kunsch C., Lang R. K., Rosen C. A., Shannon M. F. Synergistic transcriptional activation of the IL-8 gene by NF-kappa B p65 (RelA) and NF-IL-6. J. Immunol. 153:1994;153-164.
    • (1994) J. Immunol. , vol.153 , pp. 153-164
    • Kunsch, C.1    Lang, R.K.2    Rosen, C.A.3    Shannon, M.F.4
  • 21
    • 0026730105 scopus 로고
    • The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor
    • LeClair K. P., Blanar M. A., Sharp P. A. The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factor. Proc. Natl. Acad. Sci. USA. 89:1992;8145-8149.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 8145-8149
    • Leclair, K.P.1    Blanar, M.A.2    Sharp, P.A.3
  • 22
    • 0027742538 scopus 로고
    • Endothelial activation by hydrogen peroxide. Selective increases of intercellular adhesion molecule-1 and major histocompatibility complex class I
    • Bradley J. R., Johnson D. R., Pober J. S. Endothelial activation by hydrogen peroxide. Selective increases of intercellular adhesion molecule-1 and major histocompatibility complex class I. Am. J. Pathol. 142:1993;1598-1609.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1598-1609
    • Bradley, J.R.1    Johnson, D.R.2    Pober, J.S.3
  • 23
    • 0030007550 scopus 로고    scopus 로고
    • Signals leading to the activation of NF-kappa B transcription factor are stronger in neonatal than adult T lymphocytes
    • Kilpinen S., Henttinen T., Lahdenpohja N., Hulkkonen J., Hurme M. Signals leading to the activation of NF-kappa B transcription factor are stronger in neonatal than adult T lymphocytes. Scand. J. Immunol. 44:1996;85-88.
    • (1996) Scand. J. Immunol. , vol.44 , pp. 85-88
    • Kilpinen, S.1    Henttinen, T.2    Lahdenpohja, N.3    Hulkkonen, J.4    Hurme, M.5
  • 24
    • 0026970404 scopus 로고
    • Nuclear factor kappa B: An oxidative stress-responsive transcription factor of eukaryotic cells (a review)
    • Schreck R., Albermann K., Baeuerle P. A. Nuclear factor kappa B an oxidative stress-responsive transcription factor of eukaryotic cells (a review) . Free Radic. Res. Commun. 17:1992;221-237.
    • (1992) Free Radic. Res. Commun. , vol.17 , pp. 221-237
    • Schreck, R.1    Albermann, K.2    Baeuerle, P.A.3
  • 25
    • 0029739428 scopus 로고    scopus 로고
    • Identification of hydrogen peroxide as the relevant messenger in the activation pathway of transcription factor NF-kappa B
    • Schmidt K. N., Amstad P., Cerutti P., Baeuerle P. A. Identification of hydrogen peroxide as the relevant messenger in the activation pathway of transcription factor NF-kappa B. Adv. Exp. Med. Biol. 387:1996;63-68.
    • (1996) Adv. Exp. Med. Biol. , vol.387 , pp. 63-68
    • Schmidt, K.N.1    Amstad, P.2    Cerutti, P.3    Baeuerle, P.A.4
  • 26
    • 0028006612 scopus 로고
    • Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway
    • Anderson M. T., Staal F. J., Gitler C., Herzenberg L. A. Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway. Proc. Natl. Acad. Sci. USA. 91:1994;11527-11531.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11527-11531
    • Anderson, M.T.1    Staal, F.J.2    Gitler, C.3    Herzenberg, L.A.4
  • 27
    • 0028924841 scopus 로고
    • Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines: Evidence against a universal hypothesis involving oxygen radicals
    • Brennan P., O'Neill L. A. Effects of oxidants and antioxidants on nuclear factor kappa B activation in three different cell lines evidence against a universal hypothesis involving oxygen radicals . Biochim. Biophys. Acta. 1260:1995;167-175.
    • (1995) Biochim. Biophys. Acta. , vol.1260 , pp. 167-175
    • Brennan, P.1    O'Neill, L.A.2
  • 28
    • 0028348239 scopus 로고
    • Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1
    • Galter D., Mihm S., Droge W. Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1. Eur. J. Biochem. 221:1994;639-648.
    • (1994) Eur. J. Biochem. , vol.221 , pp. 639-648
    • Galter, D.1    Mihm, S.2    Droge, W.3
  • 29
    • 0025865317 scopus 로고
    • The inducible transcription activator NF-kappa B: Regulation by distinct protein subunits
    • Baeuerle P. A. The inducible transcription activator NF-kappa B regulation by distinct protein subunits . Biochim. Biophys. Acta. 1072:1991;63-80.
    • (1991) Biochim. Biophys. Acta. , vol.1072 , pp. 63-80
    • Baeuerle, P.A.1
  • 30
  • 31
    • 0028579755 scopus 로고
    • Structural and functional analysis of NF-kappa B. Determinants of DNA binding specificity and protein interaction
    • Schmid R. M., Liptay S., Betts J. C., Nabel G. J. Structural and functional analysis of NF-kappa B. Determinants of DNA binding specificity and protein interaction. J. Biol. Chem. 269:1994;32162-32167.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32162-32167
    • Schmid, R.M.1    Liptay, S.2    Betts, J.C.3    Nabel, G.J.4
  • 32
    • 0022930702 scopus 로고
    • Inducibility of kappa immunoglobulin enhancer-binding protein NF-kappa B by a posttranslational mechanism
    • Sen R., Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein NF-kappa B by a posttranslational mechanism. Cell. 47:1986;921-928.
    • (1986) Cell , vol.47 , pp. 921-928
    • Sen, R.1    Baltimore, D.2
  • 33
    • 0028288927 scopus 로고
    • The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction
    • Chan A. C., Desai D. M., Weiss A. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction. Ann. Rev. Immunol. 12:1994;555-592.
    • (1994) Ann. Rev. Immunol. , vol.12 , pp. 555-592
    • Chan, A.C.1    Desai, D.M.2    Weiss, A.3
  • 34
    • 0028342952 scopus 로고
    • Signal transmission between the plasma membrane and nucleus of T lymphocytes
    • Crabtree G. R., Clipstone N. A. Signal transmission between the plasma membrane and nucleus of T lymphocytes. Ann. Rev. Biochem. 63:1994;1045-1083.
    • (1994) Ann. Rev. Biochem. , vol.63 , pp. 1045-1083
    • Crabtree, G.R.1    Clipstone, N.A.2
  • 35
    • 0029814079 scopus 로고    scopus 로고
    • CD28: A signalling perspective
    • Ward S. G. CD28 a signalling perspective . Biochem. J. 318:1996;361-377.
    • (1996) Biochem. J. , vol.318 , pp. 361-377
    • Ward, S.G.1
  • 36
    • 0029984062 scopus 로고    scopus 로고
    • Antioxidant and redox regulation of gene transcription
    • Sen C. K., Packer L. Antioxidant and redox regulation of gene transcription. FASEB J. 10:1996;709-720.
    • (1996) FASEB J. , vol.10 , pp. 709-720
    • Sen, C.K.1    Packer, L.2
  • 37
    • 0028099150 scopus 로고
    • Signal transduction for nuclear factor-kappa B activation. Proposed location of antioxidant-inhibitable step
    • Suzuki Y. J., Mizuno M., Packer L. Signal transduction for nuclear factor-kappa B activation. Proposed location of antioxidant-inhibitable step. J. Immunol. 153:1994;5008-5015.
    • (1994) J. Immunol. , vol.153 , pp. 5008-5015
    • Suzuki, Y.J.1    Mizuno, M.2    Packer, L.3
  • 38
    • 0029164695 scopus 로고
    • IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase
    • Los M., Schenk H., Hexel K., Baeuerle P. A., Droge W., Schulze-Osthoff K. IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenase. EMBO J. 14:1995;3731-3740.
    • (1995) EMBO J. , vol.14 , pp. 3731-3740
    • Los, M.1    Schenk, H.2    Hexel, K.3    Baeuerle, P.A.4    Droge, W.5    Schulze-Osthoff, K.6
  • 39
    • 0027232067 scopus 로고
    • NF-kappa B and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli M., Chiu J. J., Lenardo M. J. NF-kappa B and Rel participants in a multiform transcriptional regulatory system . Int. Rev. Cytol. 143:1993;1-62.
    • (1993) Int. Rev. Cytol. , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 40
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle P. A., Baltimore D. NF-kappa B ten years after . Cell. 87:1996;13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 41
    • 0024294357 scopus 로고
    • Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor
    • Baeuerle P. A., Baltimore D. Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-kappa B transcription factor. Cell. 53:1988;211-217.
    • (1988) Cell , vol.53 , pp. 211-217
    • Baeuerle, P.A.1    Baltimore, D.2
  • 42
    • 0025078530 scopus 로고
    • Cloning of the p50 DNA binding subunit of NF-kappa B: Homology to rel and dorsal
    • Ghosh S., Gifford A. M., Riviere L. R., Tempst P., Nolan G. P., Baltimore D. Cloning of the p50 DNA binding subunit of NF-kappa B homology to rel and dorsal . Cell. 62:1990;1019-1029.
    • (1990) Cell , vol.62 , pp. 1019-1029
    • Ghosh, S.1    Gifford, A.M.2    Riviere, L.R.3    Tempst, P.4    Nolan, G.P.5    Baltimore, D.6
  • 44
    • 0025073062 scopus 로고
    • NF-kappa B, KBF1, dorsal, and related matters
    • Gilmore T. D. NF-kappa B, KBF1, dorsal, and related matters. Cell. 62:1990;841-843.
    • (1990) Cell , vol.62 , pp. 841-843
    • Gilmore, T.D.1
  • 45
    • 0028971289 scopus 로고
    • Rel/NF-kappa B/I kappa B family: Intimate tales of association and dissociation
    • Verma I. M., Stevenson J. K., Schwarz E. M., Van Antwerp D., Miyamoto S. Rel/NF-kappa B/I kappa B family intimate tales of association and dissociation . Genes Dev. 9:1995;2723-2735.
    • (1995) Genes Dev. , vol.9 , pp. 2723-2735
    • Verma, I.M.1    Stevenson, J.K.2    Schwarz, E.M.3    Van Antwerp, D.4    Miyamoto, S.5
  • 46
    • 0027436597 scopus 로고
    • Proposed NF-kappa B/I kappa B family nomenclature
    • Nabel G. J., Verma I. M. Proposed NF-kappa B/I kappa B family nomenclature. Genes Dev. 7:1993;2063-2063.
    • (1993) Genes Dev. , vol.7 , pp. 2063-2063
    • Nabel, G.J.1    Verma, I.M.2
  • 47
    • 0028834881 scopus 로고
    • Rel/NF-kappa B/I kappa B story
    • Miyamoto S., Verma I. M. Rel/NF-kappa B/I kappa B story. Adv. Cancer Res. 66:1995;255-292.
    • (1995) Adv. Cancer Res. , vol.66 , pp. 255-292
    • Miyamoto, S.1    Verma, I.M.2
  • 48
    • 0025599439 scopus 로고
    • NF-kappa B: A family of inducible and differentially expressed enhancer-binding proteins in human T cells
    • Molitor J. A., Walker W. H., Doerre S., Ballard D. W., Greene W. C. NF-kappa B a family of inducible and differentially expressed enhancer-binding proteins in human T cells . Proc. Natl. Acad. Sci. USA. 87:1990;10028-10032.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 10028-10032
    • Molitor, J.A.1    Walker, W.H.2    Doerre, S.3    Ballard, D.W.4    Greene, W.C.5
  • 49
    • 0025782658 scopus 로고
    • NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit
    • Urban M. B., Schreck R., Baeuerle P. A. NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit. EMBO J. 10:1991;1817-1825.
    • (1991) EMBO J. , vol.10 , pp. 1817-1825
    • Urban, M.B.1    Schreck, R.2    Baeuerle, P.A.3
  • 50
    • 0026742527 scopus 로고
    • The precursor of NF-kappa B p50 has I kappa B-like functions
    • Rice N. R., MacKichan M. L., Israel A. The precursor of NF-kappa B p50 has I kappa B-like functions. Cell. 71:1992;243-253.
    • (1992) Cell , vol.71 , pp. 243-253
    • Rice, N.R.1    MacKichan, M.L.2    Israel, A.3
  • 51
    • 0027195210 scopus 로고
    • Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL
    • Cogswell P. C., Scheinman R. I., Baldwin A. S. Jr. Promoter of the human NF-kappa B p50/p105 gene. Regulation by NF-kappa B subunits and by c-REL. J. Immunol. 150:1993;2794-2804.
    • (1993) J. Immunol. , vol.150 , pp. 2794-2804
    • Cogswell, P.C.1    Scheinman, R.I.2    Baldwin A.S., Jr.3
  • 52
    • 0026066613 scopus 로고
    • Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway
    • Fan C. M., Maniatis T. Generation of p50 subunit of NF-kappa B by processing of p105 through an ATP-dependent pathway. Nature. 354:1991;395-398.
    • (1991) Nature , vol.354 , pp. 395-398
    • Fan, C.M.1    Maniatis, T.2
  • 53
    • 0026842287 scopus 로고
    • The inhibitory ankyrin and activator Rel proteins
    • Nolan G. P., Baltimore D. The inhibitory ankyrin and activator Rel proteins. Curr. Opin. Genet. Dev. 2:1992;211-220.
    • (1992) Curr. Opin. Genet. Dev. , vol.2 , pp. 211-220
    • Nolan, G.P.1    Baltimore, D.2
  • 54
    • 0025943986 scopus 로고
    • The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B
    • Schmitz M. L., Baeuerle P. A. The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B. EMBO J. 10:1991;3805-3817.
    • (1991) EMBO J. , vol.10 , pp. 3805-3817
    • Schmitz, M.L.1    Baeuerle, P.A.2
  • 56
    • 0026774239 scopus 로고
    • Selection of optimal kappa B/Rel DNA-binding motifs: Interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation
    • Kunsch C., Ruben S. M., Rosen C. A. Selection of optimal kappa B/Rel DNA-binding motifs interaction of both subunits of NF-kappa B with DNA is required for transcriptional activation . Mol. Cell. Biol. 12:1992;4412-4421.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4412-4421
    • Kunsch, C.1    Ruben, S.M.2    Rosen, C.A.3
  • 57
    • 0027222952 scopus 로고
    • Acquisition of NFKB1-selective DNA binding by substitution of four amino acid residues from NFKB1 into RelA
    • Coleman T. A., Kunsch C., Maher M., Ruben S. M., Rosen C. A. Acquisition of NFKB1-selective DNA binding by substitution of four amino acid residues from NFKB1 into RelA. Mol. Cell. Biol. 13:1993;3850-3859.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3850-3859
    • Coleman, T.A.1    Kunsch, C.2    Maher, M.3    Ruben, S.M.4    Rosen, C.A.5
  • 58
    • 0028181243 scopus 로고
    • Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs
    • Sun S. C., Ganchi P. A., Beraud C., Ballard D. W., Greene W. C. Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs. Proc. Natl. Acad. Sci. USA. 91:1994;1346-1350.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1346-1350
    • Sun, S.C.1    Ganchi, P.A.2    Beraud, C.3    Ballard, D.W.4    Greene, W.C.5
  • 59
    • 0026570254 scopus 로고
    • Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative
    • Ruben S. M., Narayanan R., Klement J. F., Chen C. H., Rosen C. A. Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative. Mol. Cell. Biol. 12:1992;444-454.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 444-454
    • Ruben, S.M.1    Narayanan, R.2    Klement, J.F.3    Chen, C.H.4    Rosen, C.A.5
  • 61
    • 0026764920 scopus 로고
    • NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes
    • Kang S. M., Tran A. C., Grilli M., Lenardo M. J. NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes. Science. 256:1992;1452-1456.
    • (1992) Science , vol.256 , pp. 1452-1456
    • Kang, S.M.1    Tran, A.C.2    Grilli, M.3    Lenardo, M.J.4
  • 62
    • 0028892099 scopus 로고
    • In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells
    • Algarte M., Lecine P., Costello R., Plet A., Olive D., Imbert J. In vivo regulation of interleukin-2 receptor alpha gene transcription by the coordinated binding of constitutive and inducible factors in human primary T cells. EMBO J. 14:1995;5060-5072.
    • (1995) EMBO J. , vol.14 , pp. 5060-5072
    • Algarte, M.1    Lecine, P.2    Costello, R.3    Plet, A.4    Olive, D.5    Imbert, J.6
  • 63
    • 0028898457 scopus 로고
    • Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex: Role of tumor necrosis factor alpha
    • Pimentel-Muinos F. X., Mazana J., Fresno M. Biphasic control of nuclear factor-kappa B activation by the T cell receptor complex role of tumor necrosis factor alpha . Eur. J. Immunol. 25:1995;179-186.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 179-186
    • Pimentel-Muinos, F.X.1    Mazana, J.2    Fresno, M.3
  • 64
    • 0028902123 scopus 로고
    • Modulation of transcription factor NF kappa B activity by intracellular glutathione levels and by variations of the extracellular cysteine supply
    • Mihm S., Galter D., Droge W. Modulation of transcription factor NF kappa B activity by intracellular glutathione levels and by variations of the extracellular cysteine supply. FASEB J. 9:1995;246-252.
    • (1995) FASEB J. , vol.9 , pp. 246-252
    • Mihm, S.1    Galter, D.2    Droge, W.3
  • 66
    • 0028884935 scopus 로고
    • Studies into the effect of the tyrosine kinase inhibitor herbimycin A on NF-kappa B activation in T lymphocytes. Evidence for covalent modification of the p50 subunit
    • Mahon T. M., O'Neill L. A. Studies into the effect of the tyrosine kinase inhibitor herbimycin A on NF-kappa B activation in T lymphocytes. Evidence for covalent modification of the p50 subunit. J. Biol. Chem. 270:1995;28557-28564.
    • (1995) J. Biol. Chem. , vol.270 , pp. 28557-28564
    • Mahon, T.M.1    O'Neill, L.A.2
  • 68
    • 0027217531 scopus 로고
    • Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin
    • Hayashi T., Ueno Y., Okamoto T. Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin. J. Biol. Chem. 268:1993;11380-11388.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11380-11388
    • Hayashi, T.1    Ueno, Y.2    Okamoto, T.3
  • 69
    • 0030459341 scopus 로고    scopus 로고
    • 2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NF kappa B by PDTC
    • Brennan P., O'Neill L. A. 2-mercaptoethanol restores the ability of nuclear factor kappa B (NF kappa B) to bind DNA in nuclear extracts from interleukin 1-treated cells incubated with pyrollidine dithiocarbamate (PDTC). Evidence for oxidation of glutathione in the mechanism of inhibition of NF kappa B by PDTC. Biochem. J. 320:1996;975-981.
    • (1996) Biochem. J. , vol.320 , pp. 975-981
    • Brennan, P.1    O'Neill, L.A.2
  • 70
    • 0028960452 scopus 로고
    • Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators
    • Schmitz M. L., Stelzer G., Altmann H., Meisterernst M., Baeuerle P. A. Interaction of the COOH-terminal transactivation domain of p65 NF-kappa B with TATA-binding protein, transcription factor IIB, and coactivators. J. Biol. Chem. 270:1995;7219-7226.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7219-7226
    • Schmitz, M.L.1    Stelzer, G.2    Altmann, H.3    Meisterernst, M.4    Baeuerle, P.A.5
  • 71
    • 0023724778 scopus 로고
    • I kappa B: A specific inhibitor of the NF-kappa B transcription factor
    • Baeuerle P. A., Baltimore D. I kappa B: a specific inhibitor of the NF-kappa B transcription factor. Science. 242:1988;540-546.
    • (1988) Science , vol.242 , pp. 540-546
    • Baeuerle, P.A.1    Baltimore, D.2
  • 72
    • 0025304791 scopus 로고
    • Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA
    • Zabel U., Baeuerle P. A. Purified human I kappa B can rapidly dissociate the complex of the NF-kappa B transcription factor with its cognate DNA. Cell. 61:1990;255-265.
    • (1990) Cell , vol.61 , pp. 255-265
    • Zabel, U.1    Baeuerle, P.A.2
  • 73
    • 0027184023 scopus 로고
    • The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers
    • Fujita T., Nolan G. P., Liou H. C., Scott M. L., Baltimore D. The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers. Genes Dev. 7:1993;1354-1363.
    • (1993) Genes Dev. , vol.7 , pp. 1354-1363
    • Fujita, T.1    Nolan, G.P.2    Liou, H.C.3    Scott, M.L.4    Baltimore, D.5
  • 74
    • 0025324450 scopus 로고
    • The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control
    • Ohno H., Takimoto G., McKeithan T. W. The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control. Cell. 60:1990;991-997.
    • (1990) Cell , vol.60 , pp. 991-997
    • Ohno, H.1    Takimoto, G.2    McKeithan, T.W.3
  • 75
    • 0027960940 scopus 로고
    • Genomic structure of the candidate proto-oncogene BCL3
    • McKeithan T. W., Ohno H., Dickstein J., Hume E. Genomic structure of the candidate proto-oncogene BCL3. Genomics. 24:1994;120-126.
    • (1994) Genomics , vol.24 , pp. 120-126
    • McKeithan, T.W.1    Ohno, H.2    Dickstein, J.3    Hume, E.4
  • 76
    • 0026509949 scopus 로고
    • NF-kappa B and related proteins: Rel/dorsal homologies meet ankyrin-like repeats
    • Blank V., Kourilsky P., Israel A. NF-kappa B and related proteins Rel/dorsal homologies meet ankyrin-like repeats . Trends Biochem. Sci. 17:1992;135-140.
    • (1992) Trends Biochem. Sci. , vol.17 , pp. 135-140
    • Blank, V.1    Kourilsky, P.2    Israel, A.3
  • 78
    • 0027332498 scopus 로고
    • The I kappa B proteins: Multifunctional regulators of Rel/NF-kappa B transcription factors
    • Beg A. A., Baldwin A. S. Jr. The I kappa B proteins multifunctional regulators of Rel/NF-kappa B transcription factors . Genes Dev. 7:1993;2064-2070.
    • (1993) Genes Dev. , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin A.S., Jr.2
  • 79
    • 0027536852 scopus 로고
    • The inducible transcription factor NF-kappa B: Structure-function relationship of its protein subunits
    • Grimm S., Baeuerle P. A. The inducible transcription factor NF-kappa B structure-function relationship of its protein subunits . Biochem J. 290:1993;297-308.
    • (1993) Biochem J. , vol.290 , pp. 297-308
    • Grimm, S.1    Baeuerle, P.A.2
  • 80
    • 0026600367 scopus 로고
    • Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: Role of ankyrin repeats in the inhibition of DNA binding activity
    • Inoue J., Kerr L. D., Rashid D., Davis N., Bose H. R. Jr, Verma I. M. Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors role of ankyrin repeats in the inhibition of DNA binding activity . Proc. Natl. Acad. Sci. USA. 89:1992;4333-4337.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4333-4337
    • Inoue, J.1    Kerr, L.D.2    Rashid, D.3    Davis, N.4    Bose H.R., Jr.5    Verma, I.M.6
  • 81
    • 0025200592 scopus 로고
    • The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity
    • Urban M. B., Baeuerle P. A. The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity. Genes Dev. 4:1990;1975-1984.
    • (1990) Genes Dev. , vol.4 , pp. 1975-1984
    • Urban, M.B.1    Baeuerle, P.A.2
  • 82
    • 0026783210 scopus 로고
    • I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: A mechanism for cytoplasmic retention
    • Beg A. A., Ruben S. M., Scheinman R. I., Haskill S., Rosen C. A., Baldwin A. S. Jr. I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B a mechanism for cytoplasmic retention . Genes Dev. 6:1992;1899-1913.
    • (1992) Genes Dev. , vol.6 , pp. 1899-1913
    • Beg, A.A.1    Ruben, S.M.2    Scheinman, R.I.3    Haskill, S.4    Rosen, C.A.5    Baldwin A.S., Jr.6
  • 83
    • 0028986075 scopus 로고
    • Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation
    • Brown K., Gerstberger S., Carlson L., Franzoso G., Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science. 267:1995;1485-1488.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 84
    • 0027451924 scopus 로고
    • In vivo control of NF-kappa B activation by I kappa B alpha
    • Rice N. R., Ernst M. K. In vivo control of NF-kappa B activation by I kappa B alpha. EMBO J. 12:1993;4685-4695.
    • (1993) EMBO J. , vol.12 , pp. 4685-4695
    • Rice, N.R.1    Ernst, M.K.2
  • 85
    • 0030825717 scopus 로고    scopus 로고
    • NF-IL6 and NF-kappa B in cytokine gene regulation
    • Akira S., Kishimoto T. NF-IL6 and NF-kappa B in cytokine gene regulation. Adv. Immunol. 65:1997;1-46.
    • (1997) Adv. Immunol. , vol.65 , pp. 1-46
    • Akira, S.1    Kishimoto, T.2
  • 86
    • 0027207242 scopus 로고
    • Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: A mechanism for NF-kappa B activation
    • Beg A. A., Finco T. S., Nantermet P. V., Baldwin A. S. Jr. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha a mechanism for NF-kappa B activation . Mol. Cell. Biol. 13:1993;3301-3310.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3301-3310
    • Beg, A.A.1    Finco, T.S.2    Nantermet, P.V.3    Baldwin A.S., Jr.4
  • 87
    • 0025854741 scopus 로고
    • Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection
    • Riviere Y., Blank V., Kourilsky P., Israel A. Processing of the precursor of NF-kappa B by the HIV-1 protease during acute infection. Nature. 350:1991;625-626.
    • (1991) Nature , vol.350 , pp. 625-626
    • Riviere, Y.1    Blank, V.2    Kourilsky, P.3    Israel, A.4
  • 88
    • 0027980321 scopus 로고
    • The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B
    • Palombella V. J., Rando O. J., Goldberg A. L., Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B. Cell. 78:1994;773-785.
    • (1994) Cell , vol.78 , pp. 773-785
    • Palombella, V.J.1    Rando, O.J.2    Goldberg, A.L.3    Maniatis, T.4
  • 89
    • 0025266685 scopus 로고
    • Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B
    • Ghosh S., Baltimore D. Activation in vitro of NF-kappa B by phosphorylation of its inhibitor I kappa B. Nature. 344:1990;678-682.
    • (1990) Nature , vol.344 , pp. 678-682
    • Ghosh, S.1    Baltimore, D.2
  • 90
    • 0028929371 scopus 로고
    • Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation
    • Brockman J. A., Scherer D. C., McKinsey T. A., Hall S. M., Qi X., Lee W. Y., Ballard D. W. Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation. Mol. Cell. Biol. 15:1995;2809-2818.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2809-2818
    • Brockman, J.A.1    Scherer, D.C.2    McKinsey, T.A.3    Hall, S.M.4    Qi, X.5    Lee, W.Y.6    Ballard, D.W.7
  • 91
    • 0028985190 scopus 로고
    • Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B
    • Didonato J. A., Mercurio F., Karin M. Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B. Mol. Cell. Biol. 15:1995;1302-1311.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 1302-1311
    • Didonato, J.A.1    Mercurio, F.2    Karin, M.3
  • 92
    • 0028783318 scopus 로고
    • Inactivation of NF-kappa B inhibitor I kappa B alpha: Ubiquitin-dependent proteolysis and its degradation product
    • Li C. C., Dai R. M., Longo D. L. Inactivation of NF-kappa B inhibitor I kappa B alpha ubiquitin-dependent proteolysis and its degradation product . Biochem. Biophys. Res. Commun. 215:1995;292-301.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 292-301
    • Li, C.C.1    Dai, R.M.2    Longo, D.L.3
  • 94
    • 0030070803 scopus 로고    scopus 로고
    • Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha
    • Baldi L., Brown K., Franzoso G., Siebenlist U. Critical role for lysines 21 and 22 in signal-induced, ubiquitin-mediated proteolysis of I kappa B-alpha. J. Biol. Chem. 271:1996;376-379.
    • (1996) J. Biol. Chem. , vol.271 , pp. 376-379
    • Baldi, L.1    Brown, K.2    Franzoso, G.3    Siebenlist, U.4
  • 96
    • 0028978032 scopus 로고
    • Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
    • Traenckner E. B., Pahl H. L., Henkel T., Schmidt K. N., Wilk S., Baeuerle P. A. Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J. 14:1995;2876-2883.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 97
    • 0028970734 scopus 로고
    • Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway
    • Alkalay I., Yaron A., Hatzubai A., Orian A., Ciechanover A., Ben-Neriah Y. Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway. Proc. Natl. Acad. Sci. USA. 92:1995;10599-10603.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10599-10603
    • Alkalay, I.1    Yaron, A.2    Hatzubai, A.3    Orian, A.4    Ciechanover, A.5    Ben-Neriah, Y.6
  • 98
    • 0030600369 scopus 로고    scopus 로고
    • Optimal NF kappa B mediated transcriptional responses in Jurkat T cells exposed to oxidative stress are dependent on intracellular glutathione and costimulatory signals
    • Ginn-Pease M. E., Whisler R. L. Optimal NF kappa B mediated transcriptional responses in Jurkat T cells exposed to oxidative stress are dependent on intracellular glutathione and costimulatory signals. Biochem. Biophys. Res. Commun. 226:1996;695-702.
    • (1996) Biochem. Biophys. Res. Commun. , vol.226 , pp. 695-702
    • Ginn-Pease, M.E.1    Whisler, R.L.2
  • 99
    • 0029131339 scopus 로고
    • Involvement of a putative protein-tyrosine phosphatase and I kappa B-alpha serine phosphorylation in nuclear factor kappa B activation by tumor necrosis factor
    • Menon S. D., Guy G. R., Tan Y. H. Involvement of a putative protein-tyrosine phosphatase and I kappa B-alpha serine phosphorylation in nuclear factor kappa B activation by tumor necrosis factor. J. Biol. Chem. 270:1995;18881-18887.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18881-18887
    • Menon, S.D.1    Guy, G.R.2    Tan, Y.H.3
  • 100
    • 0028277327 scopus 로고
    • Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines
    • Pimentel-Muinos F. X., Munoz-Fernandez M. A., Fresno M. Control of T lymphocyte activation and IL-2 receptor expression by endogenously secreted lymphokines. J. Immunol. 152:1994;5714-5722.
    • (1994) J. Immunol. , vol.152 , pp. 5714-5722
    • Pimentel-Muinos, F.X.1    Munoz-Fernandez, M.A.2    Fresno, M.3
  • 101
    • 0027264083 scopus 로고
    • Nuclear factor kappa B, a mediator of lipopolysaccharide effects
    • Muller J. M., Ziegler-Heitbrock H. W., Baeuerle P. A. Nuclear factor kappa B, a mediator of lipopolysaccharide effects. Immunobiology. 187:1993;233-256.
    • (1993) Immunobiology , vol.187 , pp. 233-256
    • Muller, J.M.1    Ziegler-Heitbrock, H.W.2    Baeuerle, P.A.3
  • 102
    • 0028961589 scopus 로고
    • HIV type 1 protease activation of NF-kappa B within T lymphoid cells
    • Zhang D., Zhang N., Wick M. M., Byrn R. A. HIV type 1 protease activation of NF-kappa B within T lymphoid cells. AIDS Res. Hum. Retroviruses. 11:1995;223-230.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 223-230
    • Zhang, D.1    Zhang, N.2    Wick, M.M.3    Byrn, R.A.4
  • 103
    • 0027462682 scopus 로고
    • Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha
    • Brown K., Park S., Kanno T., Franzoso G., Siebenlist U. Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha. Proc. Natl. Acad. Sci. USA. 90:1993;2532-2536.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2532-2536
    • Brown, K.1    Park, S.2    Kanno, T.3    Franzoso, G.4    Siebenlist, U.5
  • 104
    • 0029977948 scopus 로고    scopus 로고
    • CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappa B/Rel heterodimers
    • Harhaj E. W., Maggirwar S. B., Good L., Sun S. C. CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappa B/Rel heterodimers. Mol. Cell. Biol. 16:1996;6736-6743.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 6736-6743
    • Harhaj, E.W.1    Maggirwar, S.B.2    Good, L.3    Sun, S.C.4
  • 105
    • 0030589362 scopus 로고    scopus 로고
    • Activation of nuclear factor-kappa B via T cell receptor requires a Raf kinase and Ca2+ influx. Functional synergy between Raf and calcineurin
    • Kanno T., Siebenlist U. Activation of nuclear factor-kappa B via T cell receptor requires a Raf kinase and Ca2+ influx. Functional synergy between Raf and calcineurin. J. Immunol. 157:1996;5277-5283.
    • (1996) J. Immunol. , vol.157 , pp. 5277-5283
    • Kanno, T.1    Siebenlist, U.2
  • 107
    • 0022633452 scopus 로고
    • Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide: Differential susceptibility of human lymphocyte functions
    • el-Hag A., Lipsky P. E., Bennett M., Clark R. A. Immunomodulation by neutrophil myeloperoxidase and hydrogen peroxide differential susceptibility of human lymphocyte functions . J. Immunol. 136:1986;3420-3426.
    • (1986) J. Immunol. , vol.136 , pp. 3420-3426
    • El-Hag, A.1    Lipsky, P.E.2    Bennett, M.3    Clark, R.A.4
  • 109
    • 0027269781 scopus 로고
    • 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor
    • 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J. 12:1993;2005-2015.
    • (1993) EMBO J. , vol.12 , pp. 2005-2015
    • Meyer, M.1    Schreck, R.2    Baeuerle, P.A.3
  • 110
    • 0026590541 scopus 로고
    • Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells
    • Schreck R., Meier B., Mannel D. N., Droge W., Baeuerle P. A. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells. J. Exp. Med. 175:1992;1181-1194.
    • (1992) J. Exp. Med. , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Mannel, D.N.3    Droge, W.4    Baeuerle, P.A.5
  • 111
    • 0027521838 scopus 로고
    • Differential induction of nuclear NF-kappa B by protein phosphatase inhibitors in primary and transformed human cells. Requirement for both oxidation and phosphorylation in nuclear translocation
    • Menon S. D., Qin S., Guy G. R., Tan Y. H. Differential induction of nuclear NF-kappa B by protein phosphatase inhibitors in primary and transformed human cells. Requirement for both oxidation and phosphorylation in nuclear translocation. J. Biol. Chem. 268:1993;26805-26812.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26805-26812
    • Menon, S.D.1    Qin, S.2    Guy, G.R.3    Tan, Y.H.4
  • 112
    • 0028150839 scopus 로고
    • Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction
    • Flescher E., Ledbetter J. A., Schieven G. L., Vela-Roch N., Fossum D., Dang H., Ogawa N., Talal N. Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction. J. Immunol. 153:1994;4880-4889.
    • (1994) J. Immunol. , vol.153 , pp. 4880-4889
    • Flescher, E.1    Ledbetter, J.A.2    Schieven, G.L.3    Vela-Roch, N.4    Fossum, D.5    Dang, H.6    Ogawa, N.7    Talal, N.8
  • 113
    • 0031936187 scopus 로고    scopus 로고
    • Pre-exposure to oxidative stress decreases the Nuclear Factor-κB-dependent transcription in T lymphocytes
    • Lahdenpohja N., Savinainen K., Hurme M. Pre-exposure to oxidative stress decreases the Nuclear Factor-κB-dependent transcription in T lymphocytes. J. Immunol. 160:1998;1354-1358.
    • (1998) J. Immunol. , vol.160 , pp. 1354-1358
    • Lahdenpohja, N.1    Savinainen, K.2    Hurme, M.3
  • 114
    • 0029665048 scopus 로고    scopus 로고
    • Involvement of intracellular Ca2+ in oxidant-induced NF-kappa B activation
    • Sen C. K., Roy S., Packer L. Involvement of intracellular Ca2+ in oxidant-induced NF-kappa B activation. FEBS Lett. 385:1996;58-62.
    • (1996) FEBS Lett. , vol.385 , pp. 58-62
    • Sen, C.K.1    Roy, S.2    Packer, L.3
  • 115
    • 0025089369 scopus 로고
    • Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription
    • Hazan U., Thomas D., Alcami J., Bachelerie F., Israel N., Yssel H., Virelizier J. L., Arenzana-Seisdedos F. Stimulation of a human T-cell clone with anti-CD3 or tumor necrosis factor induces NF-kappa B translocation but not human immunodeficiency virus 1 enhancer-dependent transcription. Proc. Natl. Acad. Sci. USA. 87:1990;7861-7865.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 7861-7865
    • Hazan, U.1    Thomas, D.2    Alcami, J.3    Bachelerie, F.4    Israel, N.5    Yssel, H.6    Virelizier, J.L.7    Arenzana-Seisdedos, F.8
  • 116
    • 0028067772 scopus 로고
    • ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction
    • Schieven G. L., Mittler R. S., Nadler S. G., Kirihara J. M., Bolen J. B., Kanner S. B., Ledbetter J. A. ZAP-70 tyrosine kinase, CD45, and T cell receptor involvement in UV- and H2O2-induced T cell signal transduction. J. Biol. Chem. 269:1994;20718-20726.
    • (1994) J. Biol. Chem. , vol.269 , pp. 20718-20726
    • Schieven, G.L.1    Mittler, R.S.2    Nadler, S.G.3    Kirihara, J.M.4    Bolen, J.B.5    Kanner, S.B.6    Ledbetter, J.A.7
  • 117
    • 0029074550 scopus 로고
    • Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells
    • Whisler R. L., Goyette M. A., Grants I. S., Newhouse Y. G. Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells. Arch. Biochem. Biophys. 319:1995;23-35.
    • (1995) Arch. Biochem. Biophys. , vol.319 , pp. 23-35
    • Whisler, R.L.1    Goyette, M.A.2    Grants, I.S.3    Newhouse, Y.G.4
  • 118
    • 0027199115 scopus 로고
    • Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes
    • Schieven G. L., Kirihara J. M., Myers D. E., Ledbetter J. A., Uckun F. M. Reactive oxygen intermediates activate NF-kappa B in a tyrosine kinase-dependent mechanism and in combination with vanadate activate the p56lck and p59fyn tyrosine kinases in human lymphocytes. Blood. 82:1993;1212-1220.
    • (1993) Blood , vol.82 , pp. 1212-1220
    • Schieven, G.L.1    Kirihara, J.M.2    Myers, D.E.3    Ledbetter, J.A.4    Uckun, F.M.5
  • 119
    • 0030958177 scopus 로고    scopus 로고
    • Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappa B/Rel transcription factors
    • Maggirwar S. B., Harhaj E. W., Sun S. C. Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappa B/Rel transcription factors. Mol. Cell. Biol. 17:1997;2605-2614.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2605-2614
    • Maggirwar, S.B.1    Harhaj, E.W.2    Sun, S.C.3
  • 120
    • 0026495105 scopus 로고
    • Evidence for a role of CD28RE as a response element for distinct mitogenic T cell activation signals
    • Civil A., Geerts M., Aarden L. A., Verweij C. L. Evidence for a role of CD28RE as a response element for distinct mitogenic T cell activation signals. Eur. J. Immunol. 22:1992;3041-3043.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 3041-3043
    • Civil, A.1    Geerts, M.2    Aarden, L.A.3    Verweij, C.L.4
  • 121
    • 0029000938 scopus 로고
    • RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter
    • Lai J. H., Horvath G., Subleski J., Bruder J., Ghosh P., Tan T. H. RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter. Mol. Cell Biol. 15:1995;4260-4271.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 4260-4271
    • Lai, J.H.1    Horvath, G.2    Subleski, J.3    Bruder, J.4    Ghosh, P.5    Tan, T.H.6
  • 122
    • 0031204429 scopus 로고    scopus 로고
    • Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells
    • McGuire K. L., Iacobelli M. Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells. J. Immunol. 159:1997;1319-1327.
    • (1997) J. Immunol. , vol.159 , pp. 1319-1327
    • McGuire, K.L.1    Iacobelli, M.2
  • 123
    • 0027410856 scopus 로고
    • The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family: C-Rel, p50, and p65
    • Ghosh P., Tan T. H., Rice N. R., Sica A., Young H. A. The interleukin 2 CD28-responsive complex contains at least three members of the NF kappa B family c-Rel, p50, and p65 . Proc. Natl. Acad. Sci. USA. 90:1993;1696-1700.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1696-1700
    • Ghosh, P.1    Tan, T.H.2    Rice, N.R.3    Sica, A.4    Young, H.A.5
  • 124
    • 0029977948 scopus 로고    scopus 로고
    • CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappa B/Rel heterodimers
    • Harhaj E. W., Maggirwar S. B., Good L., Sun S. C. CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappa B/Rel heterodimers. Mol. Cell Biol. 16:1996;6736-6743.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 6736-6743
    • Harhaj, E.W.1    Maggirwar, S.B.2    Good, L.3    Sun, S.C.4
  • 125
    • 0027581634 scopus 로고
    • Activation of primary human T-lymphocytes through CD2 plus CD28 adhesion molecules induces long-term nuclear expression of NF-kappa B
    • Costello R., Lipcey C., Algarte M., Cerdan C., Baeuerle P. A., Olive D., Imbert J. Activation of primary human T-lymphocytes through CD2 plus CD28 adhesion molecules induces long-term nuclear expression of NF-kappa B. Cell Growth Differ. 4:1993;329-339.
    • (1993) Cell Growth Differ. , vol.4 , pp. 329-339
    • Costello, R.1    Lipcey, C.2    Algarte, M.3    Cerdan, C.4    Baeuerle, P.A.5    Olive, D.6    Imbert, J.7
  • 126
    • 0030004897 scopus 로고    scopus 로고
    • Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
    • Chen Z. J., Parent L., Maniatis T. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell. 84:1996;853-862.
    • (1996) Cell , vol.84 , pp. 853-862
    • Chen, Z.J.1    Parent, L.2    Maniatis, T.3
  • 127
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB
    • Didonato J. A., Hayakawa M., Rothwarf D. M., Zandi E., Karin M. A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Nature. 388:1997;548-554.
    • (1997) Nature , vol.388 , pp. 548-554
    • Didonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 129
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1
    • Malinin N. L., Boldin M. P., Kovalenko A. V., Wallach D. MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature. 385:1997;540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 130
  • 131
    • 0028978217 scopus 로고
    • Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites
    • Sun S. C., Maggirwar S. B., Harhaj E. Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites. J. Biol. Chem. 270:1995;18347-18351.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18347-18351
    • Sun, S.C.1    Maggirwar, S.B.2    Harhaj, E.3
  • 132
    • 0028978032 scopus 로고
    • Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli
    • Traenckner E. B., Pahl H. L., Henkel T., Schmidt K. N., Wilk S., Baeuerle P. A. Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli. EMBO J. 14:1995;2876-2883.
    • (1995) EMBO J. , vol.14 , pp. 2876-2883
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 133
    • 0029896512 scopus 로고    scopus 로고
    • Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors
    • Good L. F., Maggirwar S. B., Kealiher A., Uhlik M., Sun S. C. Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors. Biochem. Biophys. Res. Commun. 223:1996;123-128.
    • (1996) Biochem. Biophys. Res. Commun. , vol.223 , pp. 123-128
    • Good, L.F.1    Maggirwar, S.B.2    Kealiher, A.3    Uhlik, M.4    Sun, S.C.5
  • 134
    • 0028176449 scopus 로고
    • The interleukin-8 AP-1 and kappa B-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization
    • Okamoto S., Mukaida N., Yasumoto K., Rice N., Ishikawa Y., Horiguchi H., Murakami S., Matsushima K. The interleukin-8 AP-1 and kappa B-like sites are genetic end targets of FK506-sensitive pathway accompanied by calcium mobilization. J. Biol. Chem. 269:1994;8582-8589.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8582-8589
    • Okamoto, S.1    Mukaida, N.2    Yasumoto, K.3    Rice, N.4    Ishikawa, Y.5    Horiguchi, H.6    Murakami, S.7    Matsushima, K.8
  • 135
    • 0028973059 scopus 로고
    • Regulation of IκB alpha phosphorylation by PKC- and Ca(2+)-dependent signal transduction pathways
    • Steffan N. M., Bren G. D., Frantz B., Tocci M. J., O'Neill E. A., Paya C. V. Regulation of IκB alpha phosphorylation by PKC- and Ca(2+)-dependent signal transduction pathways. J. Immunol. 155:1995;4685-4691.
    • (1995) J. Immunol. , vol.155 , pp. 4685-4691
    • Steffan, N.M.1    Bren, G.D.2    Frantz, B.3    Tocci, M.J.4    O'Neill, E.A.5    Paya, C.V.6
  • 137
    • 0028268629 scopus 로고
    • Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues
    • Koong A. C., Chen E. Y., Giaccia A. J. Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues. Cancer Res. 54:1994;1425-1430.
    • (1994) Cancer Res. , vol.54 , pp. 1425-1430
    • Koong, A.C.1    Chen, E.Y.2    Giaccia, A.J.3
  • 138
    • 0027417482 scopus 로고
    • Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events
    • Secrist J. P., Burns L. A., Karnitz L., Koretzky G. A., Abraham R. T. Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events. J. Biol. Chem. 268:1993;5886-5893.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5886-5893
    • Secrist, J.P.1    Burns, L.A.2    Karnitz, L.3    Koretzky, G.A.4    Abraham, R.T.5
  • 139
    • 0028140140 scopus 로고
    • Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases
    • Imbert V., Peyron J. F., Farahi Far D., Mari B., Auberger P., Rossi B. Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases. Biochem. J. 297:1994;163-173.
    • (1994) Biochem. J. , vol.297 , pp. 163-173
    • Imbert, V.1    Peyron, J.F.2    Farahi Far, D.3    Mari, B.4    Auberger, P.5    Rossi, B.6
  • 142
    • 0029739428 scopus 로고    scopus 로고
    • Identification of hydrogen peroxide as the relevant messenger in the activation pathway of transcription factor NF-kappaB
    • Schmidt K. N., Amstad P., Cerutti P., Baeuerle P. A. Identification of hydrogen peroxide as the relevant messenger in the activation pathway of transcription factor NF-kappaB. Adv. Exp. Med. Biol. 387:1996;63-68.
    • (1996) Adv. Exp. Med. Biol. , vol.387 , pp. 63-68
    • Schmidt, K.N.1    Amstad, P.2    Cerutti, P.3    Baeuerle, P.A.4
  • 144
    • 0030579135 scopus 로고    scopus 로고
    • The suppression of T cell function and NF(kappa)B expression by serine protease inhibitors is blocked by N-acetylcysteine
    • Breithaupt T. B., Vazquez A., Baez I., Eylar E. H. The suppression of T cell function and NF(kappa)B expression by serine protease inhibitors is blocked by N-acetylcysteine. Cell Immunol. 173:1996;124-130.
    • (1996) Cell Immunol. , vol.173 , pp. 124-130
    • Breithaupt, T.B.1    Vazquez, A.2    Baez, I.3    Eylar, E.H.4
  • 145
    • 0029866197 scopus 로고    scopus 로고
    • Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-KappaB
    • MacKichan M. L., Logeat F., Israel A. Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-KappaB. J. Biol. Chem. 271:1996;6084-6091.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6084-6091
    • MacKichan, M.L.1    Logeat, F.2    Israel, A.3
  • 147
    • 0027310696 scopus 로고
    • Inhibition of NF-kappa B activation by vitamin E derivatives
    • Suzuki Y. J., Packer L. Inhibition of NF-kappa B activation by vitamin E derivatives. Biochem. Biophys. Res. Commun. 193:1993;277-283.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 277-283
    • Suzuki, Y.J.1    Packer, L.2
  • 148
    • 0030924820 scopus 로고    scopus 로고
    • S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells
    • Geng Z., Rong Y., Lau B. H. S-allyl cysteine inhibits activation of nuclear factor kappa B in human T cells. Free Radic. Biol. Med. 23:1997;345-350.
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 345-350
    • Geng, Z.1    Rong, Y.2    Lau, B.H.3
  • 149
    • 0027076462 scopus 로고
    • Alpha-lipoic acid is a potent inhibitor of NF-kappa B activation in human T cells
    • Suzuki Y. J., Aggarwal B. B., Packer L. Alpha-lipoic acid is a potent inhibitor of NF-kappa B activation in human T cells. Biochem. Biophys. Res. Commun. 189:1992;1709-1715.
    • (1992) Biochem. Biophys. Res. Commun. , vol.189 , pp. 1709-1715
    • Suzuki, Y.J.1    Aggarwal, B.B.2    Packer, L.3
  • 151
    • 0029060049 scopus 로고
    • Transient overexpression of catalase does not inhibit TNF- or PMA-induced NF-kappa B activation
    • Suzuki Y. J., Mizuno M., Packer L. Transient overexpression of catalase does not inhibit TNF- or PMA-induced NF-kappa B activation. Biochem. Biophys. Res. Commun. 210:1995;537-541.
    • (1995) Biochem. Biophys. Res. Commun. , vol.210 , pp. 537-541
    • Suzuki, Y.J.1    Mizuno, M.2    Packer, L.3
  • 152
    • 0029113105 scopus 로고
    • Transcription factors as targets for oxidative signalling during lymphocyte activation
    • Goldstone S. D., Fragonas J. C., Jeitner T. M., Hunt N. H. Transcription factors as targets for oxidative signalling during lymphocyte activation. Biochem. Biophys. Acta. 1263:1995;114-122.
    • (1995) Biochem. Biophys. Acta , vol.1263 , pp. 114-122
    • Goldstone, S.D.1    Fragonas, J.C.2    Jeitner, T.M.3    Hunt, N.H.4
  • 153
    • 0025852479 scopus 로고
    • Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro
    • Toledano M. B., Leonard W. J. Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro. Proc. Natl. Acad. Sci. USA. 88:1991;4328-4332.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4328-4332
    • Toledano, M.B.1    Leonard, W.J.2
  • 154
    • 0022355344 scopus 로고
    • Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells
    • Schraufstatter I. U., Hinshaw D. B., Hyslop P. A., Spragg R. G., Cochrane C. G. Glutathione cycle activity and pyridine nucleotide levels in oxidant-induced injury of cells. J. Clin. Invest. 76:1985;1131-1139.
    • (1985) J. Clin. Invest. , vol.76 , pp. 1131-1139
    • Schraufstatter, I.U.1    Hinshaw, D.B.2    Hyslop, P.A.3    Spragg, R.G.4    Cochrane, C.G.5
  • 155
    • 0026625436 scopus 로고
    • Buthionine sulfoximine, an experimental tool to induce glutathione deficiency: Elucidation of glutathione and ascorbate in their role as antioxidants
    • Broquist H. P. Buthionine sulfoximine, an experimental tool to induce glutathione deficiency elucidation of glutathione and ascorbate in their role as antioxidants . Nutr. Rev. 50:1992;110-111.
    • (1992) Nutr. Rev. , vol.50 , pp. 110-111
    • Broquist, H.P.1
  • 156
    • 0024850422 scopus 로고
    • Lymphocyte proliferation in glutathione-depleted lymphocytes: Direct relationship between glutathione availability and the proliferative response
    • Hamilos D. L., Zelarney P., Mascali J. J. Lymphocyte proliferation in glutathione-depleted lymphocytes direct relationship between glutathione availability and the proliferative response . Immunopharmacology. 18:1989;223-235.
    • (1989) Immunopharmacology , vol.18 , pp. 223-235
    • Hamilos, D.L.1    Zelarney, P.2    Mascali, J.J.3
  • 157
    • 0025312043 scopus 로고
    • Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens
    • Suthanthiran M., Anderson M. E., Sharma V. K., Meister A. Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens. Proc. Natl. Acad. Sci. USA. 87:1990;3343-3347.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 3343-3347
    • Suthanthiran, M.1    Anderson, M.E.2    Sharma, V.K.3    Meister, A.4
  • 158
    • 0025677250 scopus 로고
    • Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus
    • Staal F. J., Roederer M., Herzenberg L. A. Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA. 87:1990;9943-9947.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9943-9947
    • Staal, F.J.1    Roederer, M.2    Herzenberg, L.A.3
  • 159
    • 0026056918 scopus 로고
    • DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition
    • Zabel U., Schreck R., Baeuerle P. A. DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition. J. Biol. Chem. 266:1991;252-260.
    • (1991) J. Biol. Chem. , vol.266 , pp. 252-260
    • Zabel, U.1    Schreck, R.2    Baeuerle, P.A.3
  • 160
    • 0029175712 scopus 로고
    • Redox regulation of activation of NF-kappa B transcription factor complex: Effects of N-acetylcysteine
    • Staal F. J., Anderson M. T., Herzenberg L. A. Redox regulation of activation of NF-kappa B transcription factor complex effects of N-acetylcysteine . Methods Enzymol. 252:1995;168-174.
    • (1995) Methods Enzymol. , vol.252 , pp. 168-174
    • Staal, F.J.1    Anderson, M.T.2    Herzenberg, L.A.3
  • 161
    • 0029898880 scopus 로고    scopus 로고
    • Sublethal levels of oxidative stress stimulate transcriptional activation of c-jun and suppress IL-2 promoter activation in Jurkat T cells
    • Beiqing L., Chen M., Whisler R. L. Sublethal levels of oxidative stress stimulate transcriptional activation of c-jun and suppress IL-2 promoter activation in Jurkat T cells. J. Immunol. 157:1996;160-169.
    • (1996) J. Immunol. , vol.157 , pp. 160-169
    • Beiqing, L.1    Chen, M.2    Whisler, R.L.3
  • 163
    • 0031041910 scopus 로고    scopus 로고
    • Redox regulation of the mitogen-activated protein kinase pathway during lymphocyte activation
    • Goldstone S. D., Hunt N. H. Redox regulation of the mitogen-activated protein kinase pathway during lymphocyte activation. Biochim. Biophys. Acta. 1355:1997;353-360.
    • (1997) Biochim. Biophys. Acta , vol.1355 , pp. 353-360
    • Goldstone, S.D.1    Hunt, N.H.2
  • 164
    • 0027384590 scopus 로고
    • NF-kappa B subunit-specific regulation of the interleukin-8 promoter
    • Kunsch C., Rosen C. A. NF-kappa B subunit-specific regulation of the interleukin-8 promoter. Mol. Cell Biol. 13:1993;6137-6146.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 6137-6146
    • Kunsch, C.1    Rosen, C.A.2
  • 165
    • 0027453552 scopus 로고
    • Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka T., Fujikawa K., Nishio Y., Mukaida N., Matsushima K., Kishimoto T., Akira S. Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc. Natl. Acad. Sci. USA. 90:1993;10193-10197.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10193-10197
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6    Akira, S.7
  • 168
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • Marui N., Offermann M. K., Swerlick R., Kunsch C., Rosen C. A., Ahmad M., Alexander R. W., Medford R. M. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J. Clin. Invest. 92:1993;1866-1874.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1866-1874
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3    Kunsch, C.4    Rosen, C.A.5    Ahmad, M.6    Alexander, R.W.7    Medford, R.M.8
  • 169
    • 0029785583 scopus 로고    scopus 로고
    • Critical evaluation of the free radical theory of aging. A proposal for the oxidative stress hypothesis
    • Yu B. P., Yang R. Critical evaluation of the free radical theory of aging. A proposal for the oxidative stress hypothesis. Ann. NY Acad. Sci. 786:1996;1-11.
    • (1996) Ann. NY Acad. Sci. , vol.786 , pp. 1-11
    • Yu, B.P.1    Yang, R.2
  • 170
    • 0029782304 scopus 로고    scopus 로고
    • Oxidative stress during viral infection: A review
    • Schwarz K. B. Oxidative stress during viral infection a review . Free Radic. Biol. Med. 21:1996;641-649.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 641-649
    • Schwarz, K.B.1
  • 171
    • 0026491132 scopus 로고
    • Reactive oxygen intermediates and human immunodeficiency virus (HIV) infection
    • Muller F. Reactive oxygen intermediates and human immunodeficiency virus (HIV) infection. Free Radic. Biol. Med. 13:1992;651-657.
    • (1992) Free Radic. Biol. Med. , vol.13 , pp. 651-657
    • Muller, F.1
  • 172
    • 0026338728 scopus 로고
    • Requirement for prooxidant and antioxidant states in T cell mediated immune responses. Relevance for the pathogenetic mechanisms of AIDS?
    • Droge W., Eck H. P., Gmunder H., Mihm S. Requirement for prooxidant and antioxidant states in T cell mediated immune responses. Relevance for the pathogenetic mechanisms of AIDS? Klin. Wochenschr. 69:1991;1118-1122.
    • (1991) Klin. Wochenschr. , vol.69 , pp. 1118-1122
    • Droge, W.1    Eck, H.P.2    Gmunder, H.3    Mihm, S.4
  • 174
    • 0029162485 scopus 로고
    • The role of oxidative stress in HIV disease
    • Pace G. W., Leaf C. D. The role of oxidative stress in HIV disease. Free Radic. Biol. Med. 19:1995;523-528.
    • (1995) Free Radic. Biol. Med. , vol.19 , pp. 523-528
    • Pace, G.W.1    Leaf, C.D.2
  • 175
    • 0030937092 scopus 로고    scopus 로고
    • HIV does not replicate in naive CD4 T cells stimulated with CD3/CD28
    • Roederer M., Raju P. A., Mitra D. K., Herzenberg L. A. HIV does not replicate in naive CD4 T cells stimulated with CD3/CD28. J. Clin. Invest. 99:1997;1555-1564.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1555-1564
    • Roederer, M.1    Raju, P.A.2    Mitra, D.K.3    Herzenberg, L.A.4
  • 176
    • 0030612264 scopus 로고    scopus 로고
    • Selective inhibition of 1 kappaB alpha phosphorylation and HIV-1 LTR-directed gene expression by novel antioxidant compounds
    • Lee R., Beauparlant P., Elford H., Ponka P., Hiscott J. Selective inhibition of 1 kappaB alpha phosphorylation and HIV-1 LTR-directed gene expression by novel antioxidant compounds. Virology. 234:1997;277-290.
    • (1997) Virology , vol.234 , pp. 277-290
    • Lee, R.1    Beauparlant, P.2    Elford, H.3    Ponka, P.4    Hiscott, J.5
  • 177
    • 0029670391 scopus 로고    scopus 로고
    • Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-κB transcription factor in mouse cardiac muscle
    • Helenius M., Hanninen M., Lehtinen S. K., Salminen A. Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-κB transcription factor in mouse cardiac muscle. J. Mol. Cell Cardiol. 28:1996;487-498.
    • (1996) J. Mol. Cell Cardiol. , vol.28 , pp. 487-498
    • Helenius, M.1    Hanninen, M.2    Lehtinen, S.K.3    Salminen, A.4
  • 178
    • 0029834145 scopus 로고    scopus 로고
    • Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B
    • Helenius M., Hanninen M., Lehtinen S. K., Salminen A. Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B. Biochem. J. 318:1996;603-608.
    • (1996) Biochem. J. , vol.318 , pp. 603-608
    • Helenius, M.1    Hanninen, M.2    Lehtinen, S.K.3    Salminen, A.4
  • 179
    • 0025126555 scopus 로고
    • Role of free radicals and catalytic metal ions in human disease: An overview
    • Halliwell B., Gutteridge J. M. Role of free radicals and catalytic metal ions in human disease an overview . Methods Enzymol. 186:1990;1-85.
    • (1990) Methods Enzymol. , vol.186 , pp. 1-85
    • Halliwell, B.1    Gutteridge, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.