-
1
-
-
0029839230
-
Retinoic acid biosynthesis and metabolism
-
Napoli J.L. Retinoic acid biosynthesis and metabolism. FASEB J. 10:1996;993-1001.
-
(1996)
FASEB J.
, vol.10
, pp. 993-1001
-
-
Napoli, J.L.1
-
2
-
-
0035128137
-
Metabolic conversion of retinol to retinoic acid mediates the biological responsiveness of human mammary epithelial cells to retinol
-
Hayden L.J. Metabolic conversion of retinol to retinoic acid mediates the biological responsiveness of human mammary epithelial cells to retinol. J. Cell Physiol. 186:2001;437-447.
-
(2001)
J. Cell Physiol.
, vol.186
, pp. 437-447
-
-
Hayden, L.J.1
-
3
-
-
0032958632
-
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development
-
Niederreither K., et al. Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat. Genet. 21:1999;444-448.
-
(1999)
Nat. Genet.
, vol.21
, pp. 444-448
-
-
Niederreither, K.1
-
4
-
-
0034035667
-
Hepatocyte-specific mutation establishes retinoid X receptor as a heterodimeric integrator of multiple physiological processes in the liver
-
Wan Y.J.Y., et al. Hepatocyte-specific mutation establishes retinoid X receptor as a heterodimeric integrator of multiple physiological processes in the liver. Mol. Cell. Biol. 20:2000;4436-4444.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4436-4444
-
-
Wan, Y.J.Y.1
-
5
-
-
0035836755
-
Selective ablation of retinoid X receptor in hepatocytes impairs their lifespan and regenerative capacity
-
Imai T., et al. Selective ablation of retinoid X receptor in hepatocytes impairs their lifespan and regenerative capacity. Proc. Natl. Acad. Sci. U. S. A. 98:2001;4581-4586.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 4581-4586
-
-
Imai, T.1
-
6
-
-
0028079763
-
Vitamin A, differentiation and cancer
-
Love J.M., Gudas L.J. Vitamin A, differentiation and cancer. Curr. Opin. Cell Biol. 6:1994;825-831.
-
(1994)
Curr. Opin. Cell Biol.
, vol.6
, pp. 825-831
-
-
Love, J.M.1
Gudas, L.J.2
-
7
-
-
0035893763
-
Synergistic cytotoxicity exhibited by combination treatment of selective retinoid ligands with taxol (Paclitaxel)
-
Vivat-Hannah V., et al. Synergistic cytotoxicity exhibited by combination treatment of selective retinoid ligands with taxol (Paclitaxel). Cancer Res. 61:2001;8703-8711.
-
(2001)
Cancer Res.
, vol.61
, pp. 8703-8711
-
-
Vivat-Hannah, V.1
-
8
-
-
0034961181
-
Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL
-
Altucci L., et al. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL. Nat. Med. 7:2001;680-686.
-
(2001)
Nat. Med.
, vol.7
, pp. 680-686
-
-
Altucci, L.1
-
9
-
-
0029794132
-
A decade of molecular biology of retinoic acid receptors
-
Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J. 10:1996;940-954.
-
(1996)
FASEB J.
, vol.10
, pp. 940-954
-
-
Chambon, P.1
-
10
-
-
0027459082
-
Retinoic acid receptors and retinoid X receptors: Interactions with endogenous retinoic acids
-
Allenby G., et al. Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc. Natl. Acad. Sci. U. S. A. 90:1993;30-34.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 30-34
-
-
Allenby, G.1
-
11
-
-
0034045480
-
Transcriptional repression by nuclear receptors
-
Hu X., Lazar M.A. Transcriptional repression by nuclear receptors. Trends Endocrinol. Metab. 11:2000;6-10.
-
(2000)
Trends Endocrinol. Metab.
, vol.11
, pp. 6-10
-
-
Hu, X.1
Lazar, M.A.2
-
12
-
-
0037050017
-
Co-regulator recruitment and the mechanism of retinoic acid receptor synergy
-
Germain P., et al. Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. Nature. 415:2002;187-192.
-
(2002)
Nature
, vol.415
, pp. 187-192
-
-
Germain, P.1
-
13
-
-
0035749803
-
The promise of retinoids to fight against cancer
-
Altucci L., Gronemeyer H. The promise of retinoids to fight against cancer. Nature Rev. Cancer. 1:2001;181-193.
-
(2001)
Nature Rev. Cancer
, vol.1
, pp. 181-193
-
-
Altucci, L.1
Gronemeyer, H.2
-
14
-
-
0029643780
-
Crystal structure of the RAR-γ ligand binding domain bound to all-trans retinoic acid
-
Renaud J.P., et al. Crystal structure of the RAR-γ ligand binding domain bound to all-trans retinoic acid. Nature. 378:1995;681-689.
-
(1995)
Nature
, vol.378
, pp. 681-689
-
-
Renaud, J.P.1
-
15
-
-
0033637703
-
Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
-
Shang Y., et al. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell. 103:2000;843-852.
-
(2000)
Cell
, vol.103
, pp. 843-852
-
-
Shang, Y.1
-
16
-
-
0034527839
-
Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells
-
Sharma D., Fondell J.D. Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells. Mol. Endocrinol. 14:2000;2001-2009.
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 2001-2009
-
-
Sharma, D.1
Fondell, J.D.2
-
18
-
-
0033572682
-
RAR-independent RXR signaling induces t(15;17) leukemia cell maturation
-
Benoit G., et al. RAR-independent RXR signaling induces t(15;17) leukemia cell maturation. EMBO J. 18:1999;7011-7018.
-
(1999)
EMBO J.
, vol.18
, pp. 7011-7018
-
-
Benoit, G.1
-
19
-
-
0031571096
-
Analysis of homo- and heterodimerization of retinoid receptors in solution
-
Venepally P., et al. Analysis of homo- and heterodimerization of retinoid receptors in solution. Arch. Biochem. Biophys. 343:1997;234-242.
-
(1997)
Arch. Biochem. Biophys.
, vol.343
, pp. 234-242
-
-
Venepally, P.1
-
20
-
-
0032498228
-
Ligand- and DNA-induced dissociation of RXRtetramers
-
Chen Z.P., et al. Ligand- and DNA-induced dissociation of RXRtetramers. J. Mol. Biol. 275:1998;55-65.
-
(1998)
J. Mol. Biol.
, vol.275
, pp. 55-65
-
-
Chen, Z.P.1
-
21
-
-
0029584593
-
Nonsteroid nuclear receptors: What are genetic studies telling us about their role in real life
-
Kastner P., et al. Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life. Cell. 83:1995;859-869.
-
(1995)
Cell
, vol.83
, pp. 859-869
-
-
Kastner, P.1
-
22
-
-
0033395856
-
Selective agonists of retinoic acid receptors: Comparative toxicokinetics and embryonic exposure
-
Arafa H.M.M., et al. Selective agonists of retinoic acid receptors: comparative toxicokinetics and embryonic exposure. Arch. Toxicol. 73:2000;547-556.
-
(2000)
Arch. Toxicol.
, vol.73
, pp. 547-556
-
-
Arafa, H.M.M.1
-
23
-
-
0032977090
-
A new class of RAR subtype selective retinoids: Correlation of pharmacological effects with receptor activity
-
Vuligonda V., et al. A new class of RAR subtype selective retinoids: correlation of pharmacological effects with receptor activity. Bioorg. Med. Chem. 7:1999;263-270.
-
(1999)
Bioorg. Med. Chem.
, vol.7
, pp. 263-270
-
-
Vuligonda, V.1
-
24
-
-
85033036570
-
Retinoid-induced hypertriglyceridemia in rats is mediated by retinoic acid receptors
-
Standeven A.M., et al. Retinoid-induced hypertriglyceridemia in rats is mediated by retinoic acid receptors. Fundam. Appl. Toxicol. 33:1996;264-271.
-
(1996)
Fundam. Appl. Toxicol.
, vol.33
, pp. 264-271
-
-
Standeven, A.M.1
-
25
-
-
0036142502
-
Retinoids and their receptors in cancer development and chemoprevention
-
Sun S.Y., Lotan R. Retinoids and their receptors in cancer development and chemoprevention. Crit. Rev. Oncol. Hematol. 41:2002;41-55.
-
(2002)
Crit. Rev. Oncol. Hematol.
, vol.41
, pp. 41-55
-
-
Sun, S.Y.1
Lotan, R.2
-
26
-
-
0034679027
-
Methylation and silencing of the retinoic acid receptor-β2 gene in breast cancer
-
Widschwendter M., et al. Methylation and silencing of the retinoic acid receptor-β2 gene in breast cancer. J. Natl. Cancer Inst. 92:2000;826-832.
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 826-832
-
-
Widschwendter, M.1
-
27
-
-
0034673671
-
Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor β2 promoter in breast cancer cells
-
Sirchia S.M., et al. Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor β2 promoter in breast cancer cells. Oncogene. 19:2000;1556-1563.
-
(2000)
Oncogene
, vol.19
, pp. 1556-1563
-
-
Sirchia, S.M.1
-
28
-
-
0038527642
-
Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor
-
Di Croce L., et al. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science. 295:2002;1079-1082.
-
(2002)
Science
, vol.295
, pp. 1079-1082
-
-
Di Croce, L.1
-
29
-
-
0036558155
-
Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer
-
Sirchia S.M., et al. Endogenous reactivation of the RARβ2 tumor suppressor gene epigenetically silenced in breast cancer. Cancer Res. 62:2002;2455-2461.
-
(2002)
Cancer Res.
, vol.62
, pp. 2455-2461
-
-
Sirchia, S.M.1
-
30
-
-
0033578633
-
The targeted disruption of both alleles of RARβ2 in F9 cells results in the loss of retinoic acid-associated growth arrest
-
Faria T.N., et al. The targeted disruption of both alleles of RARβ2 in F9 cells results in the loss of retinoic acid-associated growth arrest. J.Biol. Chem. 274:1999;26783-26788.
-
(1999)
J.Biol. Chem.
, vol.274
, pp. 26783-26788
-
-
Faria, T.N.1
-
31
-
-
0029152178
-
Expression of retinoic acid receptor β mediates retinoic-induced growth arrest and apoptosis in breast cancer cells
-
Seewaldt V.L., et al. Expression of retinoic acid receptor β mediates retinoic-induced growth arrest and apoptosis in breast cancer cells. Cell Growth Differ. 6:1995;1077-1088.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 1077-1088
-
-
Seewaldt, V.L.1
-
32
-
-
0034595637
-
Evidence that retinoic acid receptor β induction by retinoids is important for tumor cell growth inhibition
-
Sun S.Y., et al. Evidence that retinoic acid receptor β induction by retinoids is important for tumor cell growth inhibition. J. Biol. Chem. 275:2000;17149-17153.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17149-17153
-
-
Sun, S.Y.1
-
33
-
-
0010378995
-
Growth inhibition of cervical cancer cells by the human retinoic acid receptor β gene
-
Geisen C., et al. Growth inhibition of cervical cancer cells by the human retinoic acid receptor β gene. Int. J. Cancer. 85:2000;289-295.
-
(2000)
Int. J. Cancer
, vol.85
, pp. 289-295
-
-
Geisen, C.1
-
34
-
-
0027535564
-
Tumor-suppressive effect of the retinoic acid receptor β in human epidermoid lung cancer cells
-
Houle B., et al. Tumor-suppressive effect of the retinoic acid receptor β in human epidermoid lung cancer cells. Proc. Natl. Acad. Sci. U. S. A. 90:1993;958-989.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 958-989
-
-
Houle, B.1
-
35
-
-
0036219575
-
Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid
-
Dawson M.I., Zhang X. Discovery and design of retinoic acid receptor and retinoid X receptor class- and subtype-selective synthetic analogs of all-trans-retinoic acid and 9-cis-retinoic acid. Curr.Med. Chem. 9:2002;623-637.
-
(2002)
Curr.Med. Chem.
, vol.9
, pp. 623-637
-
-
Dawson, M.I.1
Zhang, X.2
-
36
-
-
0036010727
-
Novel synthetic retinoids and separation of the pleiotropic retinoidal activities
-
Kagechika H. Novel synthetic retinoids and separation of the pleiotropic retinoidal activities. Curr. Med. Chem. 9:2002;591-608.
-
(2002)
Curr. Med. Chem.
, vol.9
, pp. 591-608
-
-
Kagechika, H.1
-
37
-
-
0034095669
-
Recent developments in receptor-selective retinoids
-
Nagpal S., Chandraratna R. Recent developments in receptor-selective retinoids. Curr. Pharm. Design. 6:2000;919-931.
-
(2000)
Curr. Pharm. Design
, vol.6
, pp. 919-931
-
-
Nagpal, S.1
Chandraratna, R.2
-
38
-
-
0034612290
-
Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARγ
-
Klaholz B.P., et al. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARγ Proc. Natl. Acad. Sci. U. S. A. 97:2000;6322-6327.
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 6322-6327
-
-
Klaholz, B.P.1
-
39
-
-
0034622982
-
Structural basis for isotype selectivity of the human retinoic acid nuclear receptor
-
Klaholz B.P., et al. Structural basis for isotype selectivity of the human retinoic acid nuclear receptor. J. Mol. Biol. 302:2000;155-170.
-
(2000)
J. Mol. Biol.
, vol.302
, pp. 155-170
-
-
Klaholz, B.P.1
-
40
-
-
0033868825
-
Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains
-
Bourguet W., et al. Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. Mol. Cell. 5:2000;289-298.
-
(2000)
Mol. Cell
, vol.5
, pp. 289-298
-
-
Bourguet, W.1
-
41
-
-
0029012163
-
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α
-
Bourguet W., et al. Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α Nature. 375:1995;377-382.
-
(1995)
Nature
, vol.375
, pp. 377-382
-
-
Bourguet, W.1
-
42
-
-
0034213831
-
Crystal structure of the human RXRα ligand-binding domain bound to its natural ligand: 9-cis-retinoic acid
-
Egea P.F., et al. Crystal structure of the human RXRα ligand-binding domain bound to its natural ligand: 9-cis-retinoic acid. EMBO J. 19:2000;2592-2601.
-
(2000)
EMBO J.
, vol.19
, pp. 2592-2601
-
-
Egea, P.F.1
-
43
-
-
0033179675
-
Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists
-
Gehin M., et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem. Biol. 6:1999;519-529.
-
(1999)
Chem. Biol.
, vol.6
, pp. 519-529
-
-
Gehin, M.1
-
44
-
-
0032488839
-
Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes
-
Ostrowski J., et al. Serine 232 and methionine 272 define the ligand binding pocket in retinoic acid receptor subtypes. J. Biol. Chem. 273:1998;3490-3495.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3490-3495
-
-
Ostrowski, J.1
-
45
-
-
0029116399
-
The N-terminal portion of domain E of retinoic acid receptors α and β is essential for the recognition of retinoic acid and various analogs
-
Ostrowski J., et al. The N-terminal portion of domain E of retinoic acid receptors α and β is essential for the recognition of retinoic acid and various analogs. Proc. Natl. Acad. Sci. U. S. A. 92:1995;1812-1816.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 1812-1816
-
-
Ostrowski, J.1
-
46
-
-
0034628481
-
Syntheses and structure-activity relationships of 5,6,7,8-tetrahydro-5,5,8,8-tetra-methyl-2-quinoxaline derivatives with retinoic acid receptor α agonist activity
-
Kikuchi K., et al. Syntheses and structure-activity relationships of 5,6,7,8-tetrahydro-5,5,8,8-tetra-methyl-2-quinoxaline derivatives with retinoic acid receptor α agonist activity. J. Med. Chem. 43:2000;409-419.
-
(2000)
J. Med. Chem.
, vol.43
, pp. 409-419
-
-
Kikuchi, K.1
-
47
-
-
0029761652
-
Identification of a retinoic acid receptor α subtype specific agonist
-
Teng M., et al. Identification of a retinoic acid receptor α subtype specific agonist. J. Med. Chem. 39:1996;3035-3038.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 3035-3038
-
-
Teng, M.1
-
48
-
-
0023709173
-
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity
-
Kagechika H., et al. Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity. J. Med. Chem. 31:1988;2182-2192.
-
(1988)
J. Med. Chem.
, vol.31
, pp. 2182-2192
-
-
Kagechika, H.1
-
49
-
-
0011866446
-
-
World Patent Application # 98-47,861
-
Zusi, F.C. et al. (1998) Preparation of 5-substituted 1,1,3,3-tetramethyl-2-ketoindanes as Retinoid-like Compounds. World Patent Application # 98-47,861.
-
(1998)
Preparation of 5-substituted 1,1,3,3-tetramethyl-2-ketoindanes as Retinoid-like Compounds
-
-
Zusi, F.C.1
-
50
-
-
0000438409
-
Crystallographic studies on retinoidal-active and -inactive aromatic anilides
-
Toriumi Y., et al. Crystallographic studies on retinoidal-active and -inactive aromatic anilides. J. Org. Chem. 55:1990;259-263.
-
(1990)
J. Org. Chem.
, vol.55
, pp. 259-263
-
-
Toriumi, Y.1
-
51
-
-
0027129816
-
Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor γ
-
Bernard B.A., et al. Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor γ Biochem. Biophys. Res. Commun. 186:1992;977-983.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.186
, pp. 977-983
-
-
Bernard, B.A.1
-
52
-
-
0029562846
-
Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes
-
Charpentier B., et al. Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. J. Med. Chem. 38:1995;4993-5006.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4993-5006
-
-
Charpentier, B.1
-
53
-
-
5544263313
-
Identification of retinoic acid receptor β subtype specific agonists
-
Johnson A.T., et al. Identification of retinoic acid receptor β subtype specific agonists. J. Med. Chem. 39:1996;5027-5030.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 5027-5030
-
-
Johnson, A.T.1
-
54
-
-
0028967616
-
RAR-specific agonists/antagonists which dissociate trans-activation and AP1 transrepression inhibit anchorage-independent cell proliferation
-
Chen J.Y., et al. RAR-specific agonists/antagonists which dissociate trans-activation and AP1 transrepression inhibit anchorage-independent cell proliferation. EMBO J. 14:1995;1187-1197.
-
(1995)
EMBO J.
, vol.14
, pp. 1187-1197
-
-
Chen, J.Y.1
-
55
-
-
0030875103
-
Identification of highly potent retinoic acid receptor α-selective antagonists
-
Teng M., et al. Identification of highly potent retinoic acid receptor α-selective antagonists. J. Med. Chem. 40:1997;2445-2451.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 2445-2451
-
-
Teng, M.1
-
56
-
-
0032983330
-
Identification of a novel class of retinoic acid receptor β-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells
-
Li Y., et al. Identification of a novel class of retinoic acid receptor β-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells. J. Biol. Chem. 274:1999;15360-15366.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 15360-15366
-
-
Li, Y.1
-
57
-
-
0034672081
-
Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain
-
Mata de Urquiza A., et al. Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science. 290:2000;2140-2144.
-
(2000)
Science
, vol.290
, pp. 2140-2144
-
-
Mata de Urquiza, A.1
-
58
-
-
0028087742
-
Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids
-
Boehm M.F., et al. Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids. J. Med. Chem. 37:1994;2930-2941.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 2930-2941
-
-
Boehm, M.F.1
-
59
-
-
0030812967
-
Synthesis and structure-activity relationships of potent retinoid X receptor ligands
-
Farmer L.J., et al. Synthesis and structure-activity relationships of potent retinoid X receptor ligands. Bioorg. Med. Chem. Lett. 7:1997;2393-2398.
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 2393-2398
-
-
Farmer, L.J.1
-
60
-
-
0343416993
-
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands
-
Farmer L.J., et al. Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands. Bioorg. Med. Chem. Lett. 7:1997;2747-2752.
-
(1997)
Bioorg. Med. Chem. Lett.
, vol.7
, pp. 2747-2752
-
-
Farmer, L.J.1
-
61
-
-
0029740183
-
Activation of specific RXR heterodimers by an antagonist of RXR homodimers
-
Lala D.S., et al. Activation of specific RXR heterodimers by an antagonist of RXR homodimers. Nature. 383:1996;450-453.
-
(1996)
Nature
, vol.383
, pp. 450-453
-
-
Lala, D.S.1
-
62
-
-
0036682057
-
Novel retinoid X receptor antagonists: Specific inhibition of retinoid synergism in RXR-RAR heterodimer actions
-
Takahashi B., et al. Novel retinoid X receptor antagonists: specific inhibition of retinoid synergism in RXR-RAR heterodimer actions. J. Med. Chem. 45:2002;3327-3330.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3327-3330
-
-
Takahashi, B.1
-
63
-
-
0029906356
-
Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinoid, Am80
-
Takeshita A., et al. Successful treatment of relapse of acute promyelocytic leukemia with a new synthetic retinoid, Am80. Ann. Intern. Med. 124:1996;893-896.
-
(1996)
Ann. Intern. Med.
, vol.124
, pp. 893-896
-
-
Takeshita, A.1
-
64
-
-
0032464716
-
Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: Clinical experience with a new synthetic retinoid, Am-80
-
Takeuchi M., et al. Relapsed acute promyelocytic leukemia previously treated with all-trans retinoic acid: clinical experience with a new synthetic retinoid, Am-80. Leuk. Lymphoma. 31:1998;441-451.
-
(1998)
Leuk. Lymphoma
, vol.31
, pp. 441-451
-
-
Takeuchi, M.1
-
65
-
-
0035132140
-
Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia
-
Ferrara F.F., et al. Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. Cancer Res. 61:2001;2-7.
-
(2001)
Cancer Res.
, vol.61
, pp. 2-7
-
-
Ferrara, F.F.1
-
66
-
-
0030787752
-
Retinoic acid receptor α expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status
-
Fitzgerald P., et al. Retinoic acid receptor α expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status. Cancer Res. 57:1997;2642-2650.
-
(1997)
Cancer Res.
, vol.57
, pp. 2642-2650
-
-
Fitzgerald, P.1
-
67
-
-
0033523876
-
Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells
-
Suzuki S., et al. Implication of mitochondria-derived reactive oxygen species, cytochrome C and caspase-3 in N-(4-hydroxyphenyl)retinamide-induced apoptosis in cervical carcinoma cells. Oncogene. 18:1999;6380-6387.
-
(1999)
Oncogene
, vol.18
, pp. 6380-6387
-
-
Suzuki, S.1
-
68
-
-
0033707095
-
Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptotis by the synthetic retinoid CD437 in human lung cancer cells
-
Sun S.Y., et al. Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptotis by the synthetic retinoid CD437 in human lung cancer cells. Cancer Res. 60:2000;6537-6543.
-
(2000)
Cancer Res.
, vol.60
, pp. 6537-6543
-
-
Sun, S.Y.1
-
69
-
-
0034671314
-
Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid (CD437) through upregulation of TRAIL receptors in human lung cancer cells
-
Sun S.Y., et al. Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid (CD437) through upregulation of TRAIL receptors in human lung cancer cells. Cancer Res. 60:2000;7149-7155.
-
(2000)
Cancer Res.
, vol.60
, pp. 7149-7155
-
-
Sun, S.Y.1
-
70
-
-
0029816269
-
Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl β- glucuronide
-
Formelli F., et al. Bioactivities of N-(4-hydroxyphenyl) retinamide and retinoyl β- glucuronide. FASEB J. 10:1996;1014-1024.
-
(1996)
FASEB J.
, vol.10
, pp. 1014-1024
-
-
Formelli, F.1
-
71
-
-
0029731340
-
Chemoprevention of mammary carcinoma by LGD1069 (targretin): An RXR selective ligand
-
Gottardis M.M., et al. Chemoprevention of mammary carcinoma by LGD1069 (targretin): an RXR selective ligand. Cancer Res. 56:1996;5566-5570.
-
(1996)
Cancer Res.
, vol.56
, pp. 5566-5570
-
-
Gottardis, M.M.1
-
72
-
-
0032006028
-
Beyond Tamoxifen: The RXR receptor-selective ligand LGD1069 (targretin) causes complete regression of mammary carcinoma
-
Bischoff E.D., et al. Beyond Tamoxifen: the RXR receptor-selective ligand LGD1069 (targretin) causes complete regression of mammary carcinoma. Cancer Res. 58:1998;479-484.
-
(1998)
Cancer Res.
, vol.58
, pp. 479-484
-
-
Bischoff, E.D.1
-
73
-
-
0033572472
-
Effect of the retinoid X receptor-selective ligand LGD1069 on mammary carcinoma after tamoxifen failure
-
Bischoff E.D., et al. Effect of the retinoid X receptor-selective ligand LGD1069 on mammary carcinoma after tamoxifen failure. J.Natl. Cancer Inst. 91:1999;2118-2123.
-
(1999)
J.Natl. Cancer Inst.
, vol.91
, pp. 2118-2123
-
-
Bischoff, E.D.1
-
74
-
-
0036094845
-
Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069
-
Wu K., et al. Suppression of mammary tumorigenesis in transgenic mice by the RXR-selective retinoid, LGD1069. Cancer Epidemiol. Biomarkers Prev. 11:2002;467-474.
-
(2002)
Cancer Epidemiol. Biomarkers Prev.
, vol.11
, pp. 467-474
-
-
Wu, K.1
-
75
-
-
0034326254
-
Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (Targretin)
-
Agarwal V.R., et al. Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (Targretin). Cancer Res. 60:2000;6033-6038.
-
(2000)
Cancer Res.
, vol.60
, pp. 6033-6038
-
-
Agarwal, V.R.1
-
76
-
-
0035340844
-
Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: Multinational phase II-III trial results
-
Duvic M., et al. Bexarotene is effective and safe for treatment of refractory advanced-stage cutaneous T-cell lymphoma: multinational phase II-III trial results. J. Clin. Oncol. 19:2001;2456-2471.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 2456-2471
-
-
Duvic, M.1
-
77
-
-
0031024325
-
Initial clinical trial of a selective retinoid X receptor ligand, LGD1069
-
Miller V.A., et al. Initial clinical trial of a selective retinoid X receptor ligand, LGD1069. J. Clin. Oncol. 15:1997;790-795.
-
(1997)
J. Clin. Oncol.
, vol.15
, pp. 790-795
-
-
Miller, V.A.1
|