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Volumn 92, Issue 10, 2000, Pages 826-832

Methylation and silencing of the retinoic acid receptor-β2 gene in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; 5 METHYLCYTOSINE; RETINOIC ACID; RETINOIC ACID RECEPTOR;

EID: 0034679027     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/92.10.826     Document Type: Article
Times cited : (276)

References (45)
  • 1
    • 0032449253 scopus 로고    scopus 로고
    • Breast and prostate cancer: An analysis of common epidemiological, genetic, and biochemical features
    • Lopez-Otin C, Diamandis EP. Breast and prostate cancer: an analysis of common epidemiological, genetic, and biochemical features. Endocr Rev 1998;19:365-96.
    • (1998) Endocr Rev , vol.19 , pp. 365-396
    • Lopez-Otin, C.1    Diamandis, E.P.2
  • 2
    • 0018693333 scopus 로고
    • Chemoprevention of cancer with retinoids
    • Sporn MB, Newton DL. Chemoprevention of cancer with retinoids. Fed Proc 1979;38:2528-34.
    • (1979) Fed Proc , vol.38 , pp. 2528-2534
    • Sporn, M.B.1    Newton, D.L.2
  • 3
    • 0029008108 scopus 로고
    • Retinoid Chemoprevention of aerodigestive cancer: From basic research to the clinic
    • Ki Hong W, Lippman SM, Hittelmann WN, Lotan R. Retinoid Chemoprevention of aerodigestive cancer: from basic research to the clinic. Clin Cancer Res 1995;1:677-86.
    • (1995) Clin Cancer Res , vol.1 , pp. 677-686
    • Ki Hong, W.1    Lippman, S.M.2    Hittelmann, W.N.3    Lotan, R.4
  • 5
    • 0027982042 scopus 로고
    • Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen
    • Anzano MA, Byers SW, Smith JM, Peer CW, Mullen LT, Brown CC, et al. Prevention of breast cancer in the rat with 9-cis-retinoic acid as a single agent and in combination with tamoxifen. Cancer Res 1994;54:4614-7.
    • (1994) Cancer Res , vol.54 , pp. 4614-4617
    • Anzano, M.A.1    Byers, S.W.2    Smith, J.M.3    Peer, C.W.4    Mullen, L.T.5    Brown, C.C.6
  • 6
    • 13344259303 scopus 로고    scopus 로고
    • Chemoprevention of mammary carcinogenesis in the rat: Combined use of raloxifene and 9-cis-retinoic acid
    • Anzano MA, Peer CW, Smith JM, Mullen LT, Shrader MW, Logsdon DL, et al. Chemoprevention of mammary carcinogenesis in the rat: combined use of raloxifene and 9-cis-retinoic acid. J Natl Cancer Inst 1996;88:123-5.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 123-125
    • Anzano, M.A.1    Peer, C.W.2    Smith, J.M.3    Mullen, L.T.4    Shrader, M.W.5    Logsdon, D.L.6
  • 7
    • 0024404265 scopus 로고
    • Differential expression and ligand regulation of the retinoic acid receptor a and β genes
    • de The H, Marchio A, Tiollais P, Dejean A. Differential expression and ligand regulation of the retinoic acid receptor a and β genes. EMBO J 1989;8:429-33.
    • (1989) EMBO J , vol.8 , pp. 429-433
    • De The, H.1    Marchio, A.2    Tiollais, P.3    Dejean, A.4
  • 9
    • 0025690708 scopus 로고
    • A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter
    • Hoffmann B, Lehmann JM, Zhang XK, Hermann T, Husmann M, Graupner G, et al. A retinoic acid receptor-specific element controls the retinoic acid receptor-beta promoter. Mol Endocrinol 1990;4:1727-36.
    • (1990) Mol Endocrinol , vol.4 , pp. 1727-1736
    • Hoffmann, B.1    Lehmann, J.M.2    Zhang, X.K.3    Hermann, T.4    Husmann, M.5    Graupner, G.6
  • 10
    • 0028147929 scopus 로고
    • Down-regulation of retinoic acid receptor β in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells
    • Swisshelm K, Ryan K, Lee X, Tsou HC, Peacocke M, Sager R. Down-regulation of retinoic acid receptor β in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells. Cell Growth Differ 1994;5:133-11.
    • (1994) Cell Growth Differ , vol.5 , pp. 133-211
    • Swisshelm, K.1    Ryan, K.2    Lee, X.3    Tsou, H.C.4    Peacocke, M.5    Sager, R.6
  • 11
    • 0029003295 scopus 로고
    • Effects of relinoic acid and γ-interferon on expression of retinoic acid receptor and cellular retinoic acid-binding protein in breast cancer cells
    • Widschwendter M, Daxenbichler G, Dapunt O, Marth C. Effects of relinoic acid and γ-interferon on expression of retinoic acid receptor and cellular retinoic acid-binding protein in breast cancer cells. Cancer Res 1995;55:2135-9.
    • (1995) Cancer Res , vol.55 , pp. 2135-2139
    • Widschwendter, M.1    Daxenbichler, G.2    Dapunt, O.3    Marth, C.4
  • 12
    • 0027986810 scopus 로고
    • A specific detect in the retinoic acid receptor associated with human lung cancer cell lines
    • Zhang XK, Liu Y, Lee MO, Pfahl M. A specific detect in the retinoic acid receptor associated with human lung cancer cell lines. Cancer Res 1994;54:5663-9.
    • (1994) Cancer Res , vol.54 , pp. 5663-5669
    • Zhang, X.K.1    Liu, Y.2    Lee, M.O.3    Pfahl, M.4
  • 13
    • 0028305671 scopus 로고
    • Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues
    • Xu XC, Ro JY, Lee JS, Shin DM, Hong WK, Lotan R. Differential expression of nuclear retinoid receptors in normal, premalignant, and malignant head and neck tissues. Cancer Res 1994;54:3580-7.
    • (1994) Cancer Res , vol.54 , pp. 3580-3587
    • Xu, X.C.1    Ro, J.Y.2    Lee, J.S.3    Shin, D.M.4    Hong, W.K.5    Lotan, R.6
  • 14
    • 0027535564 scopus 로고
    • Tumor-suppressive effect of the retinoic acid receptor β in human epidermoid lung cancer cells
    • Houle B, Rochette-Egly C, Bradley WE. Tumor-suppressive effect of the retinoic acid receptor β in human epidermoid lung cancer cells. Proc Natl Acad Sci U S A 1993;90:985-9.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 985-989
    • Houle, B.1    Rochette-Egly, C.2    Bradley, W.E.3
  • 15
    • 0030066105 scopus 로고    scopus 로고
    • Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells
    • Liu Y, Lee MO, Wang HG, Li Y, Hashimoto Y, Klaus M, et al. Retinoic acid receptor β mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cells. Mol Cell Biol 1996;16:1138-49.
    • (1996) Mol Cell Biol , vol.16 , pp. 1138-1149
    • Liu, Y.1    Lee, M.O.2    Wang, H.G.3    Li, Y.4    Hashimoto, Y.5    Klaus, M.6
  • 16
    • 0029041889 scopus 로고
    • Cellular aging and transformation suppression: A role for retinoic acid receptor beta 2
    • Lee X, Si SP, Tsou HC, Peacocke M. Cellular aging and transformation suppression: a role for retinoic acid receptor beta 2. Exp Cell Res 1995;218:296-304.
    • (1995) Exp Cell Res , vol.218 , pp. 296-304
    • Lee, X.1    Si, S.P.2    Tsou, H.C.3    Peacocke, M.4
  • 17
    • 0032522485 scopus 로고    scopus 로고
    • Retinoic acid receptor β expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide
    • Sabichi AL, Hendricks DT, Bober MA, Birrer MJ. Retinoic acid receptor β expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide. J Natl Cancer Inst 1998;90:597-605.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 597-605
    • Sabichi, A.L.1    Hendricks, D.T.2    Bober, M.A.3    Birrer, M.J.4
  • 18
    • 0030828338 scopus 로고    scopus 로고
    • Loss of retinoic acid receptor β expression in breast cancer and morphologically normal adjacent tissue but not in the normal breast tissue distant from the cancer
    • Widschwendter M, Berger J, Daxenbichler G, Muller-Holzner E, Widschwendter A, Mayr A, et al. Loss of retinoic acid receptor β expression in breast cancer and morphologically normal adjacent tissue but not in the normal breast tissue distant from the cancer. Cancer Res 1997;57:4158-61.
    • (1997) Cancer Res , vol.57 , pp. 4158-4161
    • Widschwendter, M.1    Berger, J.2    Daxenbichler, G.3    Muller-Holzner, E.4    Widschwendter, A.5    Mayr, A.6
  • 19
    • 0032960181 scopus 로고    scopus 로고
    • Cancer epigenetics comes of age
    • Jones PA, Laird PW. Cancer epigenetics comes of age. Nat Genet 1999;21:163-7.
    • (1999) Nat Genet , vol.21 , pp. 163-167
    • Jones, P.A.1    Laird, P.W.2
  • 20
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-92.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6
  • 21
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995;55:4525-30.
    • (1995) Cancer Res , vol.55 , pp. 4525-4530
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6
  • 23
    • 0032497635 scopus 로고    scopus 로고
    • Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells
    • Rice JC, Massey-Brown KS, Futscher BW. Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells. Oncogene 1998;17:1807-12.
    • (1998) Oncogene , vol.17 , pp. 1807-1812
    • Rice, J.C.1    Massey-Brown, K.S.2    Futscher, B.W.3
  • 24
    • 13144307115 scopus 로고    scopus 로고
    • Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
    • Veigl ML, Kasturi L, Olechnowicz, J, Ma AH, Lutterbaugh JD, Periyasamy S, et al. Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers. Proc Natl Acad Sci U S A 1998; 95:8698-702.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8698-8702
    • Veigl, M.L.1    Kasturi, L.2    Ma, A.H.3    Lutterbaugh, J.D.4    Periyasamy, S.5
  • 26
    • 0030614832 scopus 로고    scopus 로고
    • Activation of the retinoic acid receptor β gene by 5-aza-2′-deoxycytidine in human DLD-1 colon carcinoma cells
    • Cote S, Momparler RL. Activation of the retinoic acid receptor β gene by 5-aza-2′-deoxycytidine in human DLD-1 colon carcinoma cells. Anticancer Drugs 1997;8:56-61.
    • (1997) Anticancer Drugs , vol.8 , pp. 56-61
    • Cote, S.1    Momparler, R.L.2
  • 27
    • 70449185514 scopus 로고
    • Histological grading and prognosis in breast cancer: A study of 1409 cases of which 359 have been followed for 15 years
    • Bloom HJ, Richardson WW. Histological grading and prognosis in breast cancer: a study of 1409 cases of which 359 have been followed for 15 years. Br J Cancer 1957;11:359-77.
    • (1957) Br J Cancer , vol.11 , pp. 359-377
    • Bloom, H.J.1    Richardson, W.W.2
  • 28
    • 0030916936 scopus 로고    scopus 로고
    • A single-tube PCR test for the diagnosis of Angelman and Prader-Willi syndrome based on allelic methylation differences at the SNRPN locus
    • Zeschnigk M, Lich C, Suiting K, Doerfler W, Horsthemke B. A single-tube PCR test for the diagnosis of Angelman and Prader-Willi syndrome based on allelic methylation differences at the SNRPN locus. Eur J Hum Genet 1997; 5:94-8.
    • (1997) Eur J Hum Genet , vol.5 , pp. 94-98
    • Zeschnigk, M.1    Lich, C.2    Suiting, K.3    Doerfler, W.4    Horsthemke, B.5
  • 29
    • 0031731906 scopus 로고    scopus 로고
    • Demethylation by 5-aza-2′-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells
    • Cote S, Sinnett D, Momparler RL. Demethylation by 5-aza-2′-deoxycytidine of specific 5-methylcytosine sites in the promoter region of the retinoic acid receptor beta gene in human colon carcinoma cells. Anticancer Drugs 1998; 9:743-50.
    • (1998) Anticancer Drugs , vol.9 , pp. 743-750
    • Cote, S.1    Sinnett, D.2    Momparler, R.L.3
  • 30
    • 15644381775 scopus 로고    scopus 로고
    • Progressive decrease in nuclear retinoic acid receptor βmessenger RNA level during breast carcinogenesis
    • Xu XC, Sneige N, Liu X, Nandagiri R, Lee JJ, Lukmanji F, et al. Progressive decrease in nuclear retinoic acid receptor βmessenger RNA level during breast carcinogenesis. Cancer Res 1997;57:4992-6.
    • (1997) Cancer Res , vol.57 , pp. 4992-4996
    • Xu, X.C.1    Sneige, N.2    Liu, X.3    Nandagiri, R.4    Lee, J.J.5    Lukmanji, F.6
  • 32
    • 0029044431 scopus 로고
    • Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin
    • Lotan R, Xu XC, Lippman SM, Ro JY, Lee JS, Lee JJ, et al. Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isotretinoin. N Engl J Med 1995;332:1405-10.
    • (1995) N Engl J Med , vol.332 , pp. 1405-1410
    • Lotan, R.1    Xu, X.C.2    Lippman, S.M.3    Ro, J.Y.4    Lee, J.S.5    Lee, J.J.6
  • 33
    • 0030868391 scopus 로고    scopus 로고
    • Retinoid-induced chromatin structure alterations in the retinoic acid receptor β2 promoter
    • Bhattacharyya N, Dey A, Minucci S, Zimmer A, John S, Hager G, et al. Retinoid-induced chromatin structure alterations in the retinoic acid receptor β2 promoter. Mol Cell Biol 1997; 17:6481-90.
    • (1997) Mol Cell Biol , vol.17 , pp. 6481-6490
    • Bhattacharyya, N.1    Dey, A.2    Minucci, S.3    Zimmer, A.4    John, S.5    Hager, G.6
  • 35
    • 0028875205 scopus 로고
    • Methylation of the 5′ CpG island of the p 16/ CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
    • Gonzalez-Zulueta M, Bender CM, Yang AS, Nguyen T, Beart RW, Van Tornout JM, et al. Methylation of the 5′ CpG island of the p 16/ CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res 1995;55:4531-5.
    • (1995) Cancer Res , vol.55 , pp. 4531-4535
    • Gonzalez-Zulueta, M.1    Bender, C.M.2    Yang, A.S.3    Nguyen, T.4    Beart, R.W.5    Van Tornout, J.M.6
  • 36
    • 0032528623 scopus 로고    scopus 로고
    • Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells
    • Huschtscha LI, Noble JR, Neumann AA, Moy EL, Barry P, Melki JR, et al. Loss of p16INK4 expression by methylation is associated with lifespan extension of human mammary epithelial cells. Cancer Res 1998;58:3508-12.
    • (1998) Cancer Res , vol.58 , pp. 3508-3512
    • Huschtscha, L.I.1    Noble, J.R.2    Neumann, A.A.3    Moy, E.L.4    Barry, P.5    Melki, J.R.6
  • 37
  • 38
    • 0033105363 scopus 로고    scopus 로고
    • Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability
    • Fleisher AS, Esteller M, Wang S, Tamura G, Suzuki H, Yin J, et al. Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability. Cancer Res 1999;59:1090-5.
    • (1999) Cancer Res , vol.59 , pp. 1090-1095
    • Fleisher, A.S.1    Esteller, M.2    Wang, S.3    Tamura, G.4    Suzuki, H.5    Yin, J.6
  • 39
    • 0030461224 scopus 로고    scopus 로고
    • Loss of heterozygosity in normal tissue adjacent to breast carcinomas
    • Deng G, Lu Y, Zlotnikov G, Thor AD, Smith HS. Loss of heterozygosity in normal tissue adjacent to breast carcinomas. Science 1996; 274:2057-9.
    • (1996) Science , vol.274 , pp. 2057-2059
    • Deng, G.1    Lu, Y.2    Zlotnikov, G.3    Thor, A.D.4    Smith, H.S.5
  • 40
    • 0032948005 scopus 로고    scopus 로고
    • Synergy of demethylation and histone deacetylase inhibition in the reexpression of genes silenced in cancer
    • Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB. Synergy of demethylation and histone deacetylase inhibition in the reexpression of genes silenced in cancer. Nat Genet 1999;21:103-7.
    • (1999) Nat Genet , vol.21 , pp. 103-107
    • Cameron, E.E.1    Bachman, K.E.2    Myohanen, S.3    Herman, J.G.4    Baylin, S.B.5
  • 41
    • 0030969335 scopus 로고    scopus 로고
    • Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization
    • Wu Q, Li Y, Liu R, Agadir A, Lee MO, Liu Y, et al. Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization. EMBO J 1997;16:1656-69.
    • (1997) EMBO J , vol.16 , pp. 1656-1669
    • Wu, Q.1    Li, Y.2    Liu, R.3    Agadir, A.4    Lee, M.O.5    Liu, Y.6
  • 42
    • 0033587758 scopus 로고    scopus 로고
    • Elevated retinoic acid receptor β(4) protein in human breast tumor cells with nuclear and cytoplasmic localization
    • Sommer KM, Chen LI, Treuting PM, Smith LT, Swisshelm K. Elevated retinoic acid receptor β(4) protein in human breast tumor cells with nuclear and cytoplasmic localization. Proc Natl Acad Sci U S A 1999;96:8651-6.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 8651-8656
    • Sommer, K.M.1    Chen, L.I.2    Treuting, P.M.3    Smith, L.T.4    Swisshelm, K.5
  • 43
  • 45
    • 0032905851 scopus 로고    scopus 로고
    • 5-Aza-2′-deoxycyridine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model
    • Lantry LE, Zhang Z, Crist KA, Wang Y, Kelloff GJ, Lubet RA, et al. 5-Aza-2′-deoxycyridine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model. Carcinogenesis 1999;20:343-6.
    • (1999) Carcinogenesis , vol.20 , pp. 343-346
    • Lantry, L.E.1    Zhang, Z.2    Crist, K.A.3    Wang, Y.4    Kelloff, G.J.5    Lubet, R.A.6


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