Temporal formation of distinct thyroid hormone receptor coactivator complexes in HeLa cells

Molecular Endocrinology

Volumn 14, Issue 12, 2000, Pages 2001-2009

  Sharma, Dipali ^a   Fondell, Joseph D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HISTONE ACETYLTRANSFERASE; THYROID HORMONE; THYROID HORMONE RECEPTOR;

ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE ACTIVATION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

EID: 0034527839     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.14.12.0567     Document Type: Article

References (38)

1. The nuclear receptor super-family: The second decade
2. Thyroid hormone receptors: Multiple forms, multiple possibilities
3. Advances in our understanding of thyroid hormone action at the cellular level
4. Ligand-induced recruitment of a histone deacetylase in the negative- feedback regulation of the thyrotropin β gene
5. Nuclear receptor corepressors activate rather than suppress basal transcription of genes that are negatively regulated by thyroid hormone
6. The coregulator exchange in transcriptional functions of nuclear receptors
7. Nuclear receptor coregulators: Cellular and molecular biology
8. Role of CBP/P300 in nuclear receptor signalling
9. Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300
10. p300 is a component of an estrogen receptor coactivator complex
11. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
12. The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function
13. The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways
14. The histone acetylase PCAF is a nuclear receptor coactivator
15. Steroid receptor coactivator-1 is a histone acetyltransferase
16. Structure and specificity of nuclear receptor-coactivator interactions
17. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
18. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
19. Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex
20. Thyroid hormone receptor-associated proteins and general positive cofactors mediate thyroid hormone receptor function in the absence of the TATA box-binding protein-associated factors of TFIID
21. A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system
22. NAT, a human complex containing Srb polypeptides that functions as a negative regulator of activated transcription
23. A novel human SRB/MED-containing cofactor complex, SMCC, involved in transcription regulation
24. The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1
25. The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain
26. The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
27. Specific structural motifs determine TRAP220 interactions with nuclear hormone receptors
28. Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators
29. Rapid effects of triiodothyronine on hepatic gene expression. Hybridization analysis of tissue-specific triiodothyronine regulation of mRNA S14
30. Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase
31. Functional synergism between multiple thyroid hormone response elements regulates hepatic expression of the rat S14 gene
32. A novel retinoid x receptor-independent thyroid hormone response element is present in the human type 1 deiodinase gene
33. Competition between thyroid hormone receptor-associated protein (TRAP) 220 and transcriptional intermediary factor (TIF) 2 for binding to nuclear receptors. Implications for the recruitment of TRAP and p160 coactivator complexes
34. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
35. TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors
36. An activity gel assay detects a single, catalytically active histone acetyltransferase subunit in Tetrahymena macronuclei
37. Identification of mouse TRAP100: A transcriptional coregulatory factor for thyroid hormone and vitamin D receptors
38. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray