Inhibitors of histone deacetylase and DNA methyltransferase synergistically activate the methylated metallothionein I promoter by activating the transcription factor MTF-1 and forming an open chromatin structure

Molecular and Cellular Biology

Volumn 22, Issue 23, 2002, Pages 8302-8319

  Ghoshal, Kalpana ^a   Datta, Jharna ^a   Majumder, Sarmila ^a   Bai, Shoumei ^a   Dong, Xiaocheng ^a   Parthun, Mark ^a   Jacob, Samson T ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZACITIDINE; DEPSIPEPTIDE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE INHIBITOR; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HISTONE H3; HISTONE H4; LYSINE; METALLOTHIONEIN; METHYL CPG BINDING PROTEIN; METHYL CPG BINDING PROTEIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF1; TRICHOSTATIN A; UNCLASSIFIED DRUG;

ACETYLATION; ANTIBODY SPECIFICITY; ARTICLE; BINDING AFFINITY; CHROMATIN STRUCTURE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CPG ISLAND; DEMETHYLATION; DNA BINDING; DNA FOOTPRINTING; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENE ISOLATION; GENE MAPPING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; INHIBITION KINETICS; LYMPHOSARCOMA; METHYLATION; MTF1 GENE; PRIORITY JOURNAL; PROMOTER REGION; STATISTICAL SIGNIFICANCE;

ACETYLATION; ANIMALS; AZACITIDINE; BASE SEQUENCE; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA FOOTPRINTING; DNA-BINDING PROTEINS; ENZYME INHIBITORS; HISTONE DEACETYLASES; HISTONES; HYDROXAMIC ACIDS; METALLOTHIONEIN; METHYL-CPG-BINDING PROTEIN 2; MICE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; ZINC;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0036889153     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.22.23.8302-8319.2002     Document Type: Article

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