Genomic structure and chromosomal mapping of the murine and human Mbd1, Mbd2, Mbd3, and Mbd4 genes

Mammalian Genome

Volumn 10, Issue 9, 1999, Pages 906-912

  Hendrich, Brian ^a   Abbott, Catherine ^a   McQueen, Heather ^a   Chambers, Doreen ^a   Cross, Sally ^a   Bird, Adrian ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN;

ARTICLE; CHROMOSOME 10; CHROMOSOME 18; CHROMOSOME 19; CHROMOSOME 3; CHROMOSOME 6; CHROMOSOME MAP; DNA METHYLATION; GENE LOCATION; GENE STRUCTURE; HUMAN; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DNA BINDING;

ANIMALS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 19; CHROMOSOMES, HUMAN, PAIR 3; DNA; DNA METHYLATION; DNA PRIMERS; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; EXONS; GENOME; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTRONS; MICE; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS;

EID: 0032878344     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359901112     Document Type: Article

References (32)

1. Apte SS, Mattei M-G, Olsen BR (1994) Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22. Genomics 19, 86-90
2. Ashworth L, Batzer M, Brandriff B, Branscomb E, de Jong P et al. (1995) An integrated metric physical map of human chromosome 19. Nat Genet 11, 422-427
3. Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M (1999) A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397, 579-583
4. Boyes J, Bird A (1991) DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 64, 1123-1134
5. Brown R, Hirst G, Gallagher W, Mellwrath A, Margison G et al. (1997) hMLH1 expression and cellular responses of ovarian tumour cells to treatment with cytotoxic anticancer agents. Oncogene 15, 45-52
6. Cedur H (1988) DNA methylation and gene activity. Cell 53, 3-4
7. Cooper DN, Youssoufian H (1988) The CpG dinucleotide and human genetic disease. Hum Genet 78, 151-155
8. Cross SH, Bird AP (1995) CpG islands and genes. Curr Opin Genet Dev 5, 309-314
9. Cross S, Meehan R, Nan X, Bird A (1997) A component of the transcriptional repressor MeCPI shares a motif with DNA methyltransferase and HRX proteins. Nat Genet 13, 256-259
10. Cross S, Clark VH, Bird AP (1999) Isolation of Cpb islands from large genomic clones. Nucleic Acids Res 27, 2099-2107.
11. Deloukas P, Schuler GD, Gyapay G, Beasley EM, Soderlund C et al. (1998) A physical map of 30,000 human genes. Science. 282, 744-746
12. D'Esposito M, Quaderi NA, Ciccodicola A, Bruni P, Esposito T et al. (1996) Isolation, physical mapping, and Northern analysis of the X-linked human gene encoding methyl CpG-binding protein, MECP2. Mamm Genome 7, 533-535
13. Frederico LA, Kunkel TA, Ramsay Shaw B (1990) A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. Biochemistry 29, 2532-2537
14. Hendrich B, Bird A (1998) Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol 18, 6538-6547
15. Kelner MJ, Montoya MA (1998) Structural organisation of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3. Biochem Biophys Res Commun 249, 53-55
16. Keshet I, Leiman-Hurwitz J, Cedar H (1986) DNA methylation affects the formation of active chromatin. Cell 44, 535-543
17. Lewis JD, Meehan RR, Henzel WJ, Maurer-Fogy I, Jeppesen P et al. (1992) Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA. Cell 69, 905-914
18. Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926
19. Li L, Chin L-S, Greengard P, Copeland NG, Gilbert DJ et al. (1995) Localization of the synapsin II (SYN2) gene to human chromosome 3 and mouse chromosome 6. Genomics 28, 365-366
20. Manly KF (1993) A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm Genome 4, 303-313
21. Nan X, Meehan RR, Bird A (1993) Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2. Nucleic Acids Res 21, 4886-4892
22. Nan X, Campoy F, Bird A (1997) MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88, 471-481
23. Nathans J, Thomas D, Hogness DS (1986) Molecular genetics of human color vision: the genes encoding blue, green, and red pigments. Science 232, 193-202
24. Ng H-H, Zhang Y, Hendrich B, Johnson CA, Turner BM et al. (1999) MBD2 is a transcriptional repressor belonging to the McCP1 histone deacetylase complex. Nat Genet (in press)
25. Papadopoulos N, Nicolaides NC, Wei Y-F, Ruben SM, Carter KC et al. (1994) Mutation of a mutL homolog in hereditary colon cancer. Science 263, 1625-1629
26. Pasini B, Hofstra RMW, Yin L, Bocciardi R, Santamaria G et al. (1995) The physical map of the human RET proto-oncogene. Oncogene 11, 1737-1743
27. Pennacchio LA, Lehesjoki A-E, Stone NE, Willour VL, Virtaneva K et al. (1996) Mutations in the gene encoding cystatin B in progressive myoclonus epilepsy (EPMI). Science 271, 1731-1733
28. Quaderi NA, Meehan RR, Tate PH, Cross SH, Bird AP et al. (1994) Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome. Genomics 22, 648-651
29. Rideout WMI, Coetzee GA, Olurni AF, Jones PA (1990) 5-methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249, 1288-1290
30. Rowe L, Nadeau J, Turner R, Frankel W, Letts V et al. (1994) Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm Genome 5, 253-274
31. Shen J-C, Rideout WMI, Jones PA (1994) The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res 22, 972-976
32. Tate PH, Bird AP (1993) Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 3, 226-231