IL-5-induced integrin adhesion of human eosinophils caused by ERK1/2-mediated activation of cPLA 2

Journal of Leukocyte Biology

Volumn 72, Issue 5, 2002, Pages 1046-1053

  Zhu, Xiangdong ^a   Jacobs, Benjamin ^a   Boetticher, Evan ^a   Myou, Shigeharu ^a   Meliton, Angelo ^a   Sano, Hiroyuki ^b   Lambertino, Anissa T ^a   Muñoz, Nilda M ^a   Leff, Alan R ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b TOTTORI UNIVERSITY   (Japan)

Author keywords

Adhesion molecules; Arachidonic acid; Signal transduction

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; INTEGRIN; INTERLEUKIN 5; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE A2; PROTEIN INHIBITOR; PROTEIN KINASE P60; PROTEIN TYROSINE KINASE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; EOSINOPHILIA; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IMMUNOREGULATION; INCUBATION TIME; INHIBITION KINETICS; PRIORITY JOURNAL; PROTEIN BINDING; REGULATORY MECHANISM; TIME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL ADHESION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; EOSINOPHILS; HUMANS; INTEGRINS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-5; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOLIPASES A; PROTEIN-TYROSINE KINASES;

JANUS;

EID: 0036855471     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Mould, A. W., Matthaei, K. I., Young, I. G., Foster, P. S. (1997) Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice. J. Clin. Investig. 99, 1064-1071.
2. Walsh, G. M., Hartnell, A., Wardlaw, A. J., Kurihara, K., Sanderson, C. J., Kay, A. B. (1990) IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leucocyte integrin (CD11/18)-dependent manner. Immunology 71, 258-265.
3. Zhu, X., Munoz, N. M., Kim, K. P., Sano, H., Cho, W., Leff, A. R. (1999) Cytosolic phospholipase A2 activation is essential for beta 1 and beta 2 integrin-dependent adhesion of human eosinophils. J. Immunol. 163, 3423-3429.
4. Sano, H., Zhu, X., Sano, A., Boetticher, E. E., Shioya, T., Jacobs, B., Munoz, N. M., Leff, A. R. (2001) Extracellular signal-regulated kinase 1/2-mediated phosphorylation of cytosolic phospholipase A2 is essential for human eosinophil adhesion to fibronectin. J. Immunol. 166, 3515-3521.
5. Myou, S., Sano, H., Fujimura, M., Zhu, X., Kurashima, K., Kita, T., Nakao, S., Nonomura, A., Shioya, T., Kim, K. P., Munoz, N. M., Cho, W., Leff, A. R. (2001) Blockade of eosinophil migration and airway hyperresponsiveness by cPLA2-inhibition. Nat. Immunol. 2, 145-149.
6. Nagase, T., Uozumi, N., Ishii, S., Kume, K., Izumi, T., Ouchi, Y., Shimizu, T. (2000) Acute lung injury by sepsis and acid aspiration: A key role for cytosolic phospholipase A2. Nat. Immunol. 1, 42-46.
7. Lin, L. L., Wartmann, M., Lin, A. Y., Knopf, J. L., Seth, A., Davis, R. J. (1993) cPLA2 is phosphorylated and activated by MAP kinase. Cell 72, 269-278.
8. Hiller, G., Sundler, R. (1999) Activation of arachidonate release and cytosolic phospholipase A2 via extracellular signal-regulated kinase and p38 mitogen-activated protein kinase in macrophages stimulated by bacteria or zymosan. Cell. Signal. 11, 863-869.
9. Kramer, R. M., Roberts, E. F., Um, S. L., Borsch-Haubold, A. G., Watson, S. P., Fisher, M. J., Jakubowski, J. A. (1996) p38 mitogen-activated protein kinase phosphorylates cytosolic phospholipase A2 (cPLA2) in thrombin-stimulated platelets. Evidence that proline-directed phosphorylation is not required for mobilization of arachidonic acid by cPLA2. J. Biol. Chem. 271, 27723-27729.
10. Hernandez, M., Bayon, Y., Sanchez Crespo, M., Nieto, M. L. (1999) Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor-alpha: Phosphorylation of cytosolic phospholipase A2 and transactivation of cyclooxygenase-2. J. Neurochem. 73, 1641-1649.
11. Waterman, W. H., Molski, T. F., Huang, C. K., Adams, J. L., Sha'afi, R. I. (1996) Tumour necrosis factor-alpha-induced phosphorylation and activation of cytosolic phospholipase A2 are abrogated by an inhibitor of the p38 mitogen-activated protein kinase cascade in human neutrophils. Biochem. J. 319, 17-20.
12. Zhu, X., Sano, H., Kim, K. P., Sano, A., Boetticher, E., Munoz, N. M., Cho, W., Leff, A. R. (2001) Role of mitogen-activated protein kinase-mediated cytosolic phospholipase A(2) activation in arachidonic acid metabolism in human eosinophils. J. Immunol. 167, 461-468.
13. Bracke, M., Nijhuis, E., Lammers, J. W., Coffer, P. J., Koenderman, L. (2000) A critical role for PI 3-kinase in cytokine-induced Fcalpha-receptor activation. Blood 95, 2037-2043.
14. Vanhaesebroeck, B., Leevers, S. J., Panayotou, G., Waterfield, M. D. (1997) Phosphoinositide 3-kinases: A conserved family of signal transducers. Trends Biochem. Sci. 22, 267-272.
15. Coffer, P. J., Schweizer, R. C., Dubois, G. R., Maikoe, T., Lammers, J. W., Koenderman, L. (1998) Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2-derived cytokines interleukin-4 and interleukin-5. Blood 91, 2547-2557.
16. Hansel, T. T., De Vries, I. J., Iff, T., Rihs, S., Wandzilak, M., Betz, S., Blaser, K., Walker, C. (1991) An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J. Immunol. Methods 145, 105-110.
17. Zhu, X., Subbaraman, R., Sano, H., Jacobs, B., Sano, A., Boetticher, E., Munoz, N. M., Leff, A. R. (2000) A surrogate method for assessment of beta(2)-integrin-dependent adhesion of human eosinophils to ICAM-1. J. Immunol. Methods 240, 157-164.
18. Kim, K., Jung, S. Y., Lee, D. K., Jung, J. K., Park, J. K., Kim, D. K., Lee, C. H. (1998) Suppression of inflammatory responses by surfactin, a selective inhibitor of platelet cytosolic phospholipase A2. Biochem. Pharmacol. 55, 975-985.
19. Favata, M. F., Horiuchi, K. Y., Manos, E. J., Daulerio, A. J., Stradley, D. A., Feeser, W. S., Van Dyk, D. E., Pitts, W. J., Earl, R. A., Hobbs, F., Copeland, R. A., Magolda, R. L., Scherle, P. A., Trzaskos, J. M. (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273, 18623-18632.
20. Scherle, P. A., Jones, E. A., Favata, M. F., Daulerio, A. J., Covington, M. B., Nurnberg, S. A., Magolda, R. L., Trzaskos, J. M. (1998) Inhibition of MAP kinase kinase prevents cytokine and prostaglandin E2 production in lipopolysaccharide-stimulated monocytes. J. Immunol. 161, 5681-5686.
21. Suzaki, Y., Yoshizumi, M., Kagami, S., Koyama, A. H., Taketani, Y., Houchi, H., Tsuchiya, K., Takeda, E., Tamaki, T. (2002) Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC 12 cells: Potential role in cell survival following oxidative insults. J. Biol. Chem. 277, 9614-9621.
22. Lee, J. C., Laydon, J. T., McDonnell, P. C., Gallagher, T. F., Kumar, S., Green, D., McNulty, D., Blumenthal, M. J., Heys, J. R., Landvatter, S. W., et al. (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372, 739-746.
23. Bennett, B. L., Sasaki, D. T., Murray, B. W., O'Leary, E. C., Sakata, S. T., Xu, W., Leisten, J. C., Motiwala, A., Pierce, S., Satoh, Y., Bhagwat, S. S., Manning, A. M., Anderson, D. W. (2001) SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc. Natl. Acad. Sci. USA 98, 13681-13686.
24. Knall, C., Young, S., Nick, J. A., Buhl, A. M., Worthen, G. S., Johnson, G. L. (1996) Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils. J. Biol. Chem. 271, 2832-2838.
25. Back, S. H., Bae, Y. S., Seo, J. K., Lee, Y. H., Kim, J. H., Kwun, K. B., Suh, P. G., Ryu, S. H. (1999) Trp-Lys-Tyr-Met-Val-Met activates mitogen-activated protein kinase via a PI-3 kinase-mediated pathway independent of PKC. Life Sci. 65, 1845-1856.
26. Miike, S., Kurasawa, K., Saito, Y., Iwamoto, I. (2000) Platelet-activating factor activates mitogen-activated protein kinases through the activation of phosphatidylinositol 3-kinase and tyrosine kinase in human eosinophils. J. Leukoc. Biol. 67, 117-126.
27. Arcaro, A., Wymann, M. P. (1993) Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem. J. 296, 297-301.
28. Yano, H., Nakanishi, S., Kimura, K., Hanai, N., Saitoh, Y., Fukui, Y., Nonomura, Y., Matsuda, Y. (1993) Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem. 268, 25846-25856.
29. Vlahos, C. J., Matter, W. F., Hui, K. Y., Brown, R. F. (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-henzopyran-4-one (LY294002). J. Biol. Chem. 269, 5241-5248.
30. Hanke, J. H., Gardner, J. P., Dow, R. L., Changelian, P. S., Brissette, W. H., Weringer, E. J., Pollok, B. A., Connelly, P. A. (1996) Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J. Biol. Chem. 271, 695-701.
31. Meydan, N., Grunberger, T., Dadi, H., Shahar, M., Arpaia, E., Lapidot, Z., Leeder, J. S., Freedman, M., Cohen, A., Gazit, A., Levitzki, A., Roifman, C. M. (1996) Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 379, 645-648.
32. Miike, S., Nakao, A., Hiraguri, M., Kurasawa, K., Saito, Y., Iwamoto, I. (1999) Involvement of JAK2, but not PI 3-kinase/Akt and MAP kinase pathways, in anti-apoptotic signals of GM-CSF in human eosinophils. J. Leukoc. Biol. 65, 700-706.
33. Pazdrak, K., Olszewska-Pazdrak, B., Stafford, S., Garofalo, R. P., Alam, R. (1998) Lyn, Jak2, and Raf-1 kinases are critical for the antiapoptotic effect of interleukin 5, whereas only Raf-1 kinase is essential for eosinophil activation and degranulation. J. Exp. Med. 188, 421-429.
34. Lindsay, M. A., Haddad, E. B., Rousell, J., Teixeira, M. M., Hellewell, P. G., Barnes, P. J., Giembycz, M. A. (1998) Role of the mitogen-activated protein kinases and tyrosine kinases during leukotriene B4-induced eosinophil activation. J. Leukoc. Biol. 64, 555-562.
35. Alam, R., Pazdrak, K., Stafford, S., Forsythe, P. (1995) The interleukin-5/receptor interaction activates Lyn and Jak2 tyrosine kinases and propagates signals via the Ras-Raf-1-MAP kinase and the Jak-STAT pathways in eosinophils. Int. Arch. Allergy Immunol. 107, 226-227.
36. Al-Shami, A., Naccache, P. H. (1999) Granulocyte-macrophage colony-stimulating factor-activated signaling pathways in human neutrophils. Involvement of Jak2 in the stimulation of phosphatidylinositol 3-kinase. J. Biol. Chem. 274, 5333-5338.
37. Herrera-Velit, P., Reiner, N. E. (1996) Bacterial lipopolysaccharide induces the association and coordinate activation of p53/56lyn and phosphatidylinositol 3-kinase in human monocytes. J. Immunol. 156, 1157-1165.
38. Capodici, C., Hanft, S., Feoktistov, M., Pillinger, M. H. (1998) Phosphatidylinositol 3-kinase mediates chemoattractant-stimulated, CD11b/CD18-dependent cell-cell adhesion of human neutrophils: Evidence for an ERK-independent pathway. J. Immunol. 160, 1901-1909.
39. Kinashi, T., Asaoka, T., Setoguchi, R., Takatsu, K. (1999) Affinity modulation of very late antigen-5 through phosphatidylinositol 3-kinase in mast cells. J. Immunol. 162, 2850-2857.
40. Chan, A. S., Mobley, J. L., Fields, G. B., Shimizu, Y. (1997) CD7-mediated regulation of integrin adhesiveness on human T cells involves tyrosine phosphorylation-dependent activation of phosphatidylinositol 3-kinase. J. Immunol. 159, 934-942.
41. Adachi, T., Stafford, S., Sur, S., Alam, R. (1999) A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. J. Immunol. 163, 939-946.
42. Weber, C., Katayama, J., Springer, T. A. (1996) Differential regulation of beta 1 and beta 2 integrin avidity by chemoattractants in eosinophils. Proc. Natl. Acad. Sci. USA 93, 10939-10944.
43. Kumano, K., Nakao, A., Nakajima, H., Miike, S., Kurasawa, K., Saito, Y., Iwamoto, I. (2000) Blockade of JAK2 by tyrphostin AG-490 inhibits antigen-induced eosinophil recruitment into the mouse airways. Biochem. Biophys. Res. Commun. 270, 209-214.
44. Powell, W. S., Gravel, S., Halwani, F. (1999) 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of L-selectin shedding, surface expression of CD11b, actin polymerization, and calcium mobilization in human eosinophils. Am. J. Respir. Cell Mol. Biol. 20, 163-170.