5-oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of L-selectin shedding, surface expression of CD11b, actin polymerization, and calcium mobilization in human eosinophils

American Journal of Respiratory Cell and Molecular Biology

Volumn 20, Issue 1, 1999, Pages 163-170

  Powell, William S ^a,b   Gravel, Sylvie ^a   Halwani, Fawaz ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

5 OXO 6,8,11,14 ICOSATETRAENOIC ACID; 5-OXO-6,8,11,14-EICOSATETRAENOIC ACID; ACTIN; ARACHIDONIC ACID DERIVATIVE; CALCIUM; CD11B ANTIGEN; CHEMOTACTIC FACTOR; ENZYME INHIBITOR; L SELECTIN; LEUKOTRIENE B4; POLYMER; PROTEIN KINASE INHIBITOR; THROMBOCYTE ACTIVATING FACTOR;

ARTICLE; BLOOD; COMPARATIVE STUDY; EOSINOPHIL; HUMAN; KINETICS; METABOLISM;

ACTINS; ARACHIDONIC ACIDS; CALCIUM; CHEMOTACTIC FACTORS; ENZYME INHIBITORS; EOSINOPHILS; HUMANS; KINETICS; L-SELECTIN; LEUKOTRIENE B4; MACROPHAGE-1 ANTIGEN; PLATELET ACTIVATING FACTOR; POLYMERS; PROTEIN KINASE INHIBITORS;

EID: 0032608523     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.20.1.3141     Document Type: Article

References (51)

1. Teixeira, M. M., T. J. Williams, and P. G. Hellewell. 1995. Mechanisms and pharmacological manipulation of eosinophil accumulation in vivo. Trends Pharmacol. Sci. 16:418-423.
2. Bousquet, J., P. Chanez, A. M. Vignola, J. Y. Lacoste, and F. B. Michel. 1994. Eosinophil inflammation in asthma. Am. J. Respir. Crit. Care Med. 150:S33-S38.
3. Schleimer, R. P., S. A. Sterbinsky, J. Kaiser, C. A. Bickel, D. A. Klunk, K. Tomioka, W. Newman, F. W. Luscinskas, M. A. Gimbrone, Jr., B. W. McIntyre, and B. S. Bochner. 1992. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: association with expression of VCAM-1. J. Immunol. 148:1086-1092.
4. Kameyoshi, Y., A. Dorschner, A. I. Mallet, E. Christophers, and J. M. Schröder. 1992. Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils. J. Exp. Med. 176: 587-592.
5. Garcia-Zepeda, E. A., M. E. Rothenberg, R. T. Ownbey, J. Celestin, P. Leder, and A. D. Luster. 1996. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue cosinophilia. Nat. Med 2:449-456.
6. Wardlaw, A. J., R. Moqbel, O. Cromwell, and A. B. Kay. 1986. Platelet-activating factor: a potent chemotactic and chemokinetic factor for human eosinophils. J. Clin. Invest. 78:1701-1706.
7. 4 and 8(S),15(S)-dihydroxy-5,9,11,13(Z,E,Z,E)-eicosatetraenoic acid. J. Immunol. 147:2276-2283.
8. 4 receptors on guinea pig alveolar eosinophils. J. Pharmacol. Exp. Ther. 258:784-789.
9. Powell, W. S., D. Chung, and S. Gravel. 1995. 5-Oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of human cosinophil migration. J. Immunol. 154:4123-4132.
10. Sun, F. F., N. J. Crittenden, C. I. Czuk, B. M. Taylor, B. K. Stout, and H. G. Johnson. 1991. Biochemical and functional differences between eosinophils from animal species and man. J. Leukoc. Biol. 50:140-150.
11. Ford-Hutchinson, A. W., M. A. Bray, M. V. Doig, M. E. Shipley, and M. J. Smith. 1980. Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes. Nature 286:264-265.
12. Powell, W. S., F. Gravelle, and S. Gravel. 1992. Metabolism of 5(S)-hydroxy-6,8,11,14-eicosatetraenoic acid and other 5(S)-hydroxycicosanoids by a specific dehydrogenase in human polymorphonuclear leukocytes. J. Biol. Chem. 267:19233-19241.
13. Powell, W. S., Y. Zhang, and S. Gravel. 1994. Effects of phorbol myristate acetate on the synthesis of 5-oxo-6,8,11,14-eicosatetraenoic acid by human polymorphonuclear leukocytes. Biochemistry 33:3927-3933.
14. 4 receptor. J. Biol. Chem. 268:9280-9286.
15. Powell, W. S., S. Gravel, F. Halwani, C. S. Hii, Z. H. Huang, A. M. Tan, and A. Ferrante. 1997. Effects of 5-oxo-6,8,11,14-eicosatetraenoic acid on expression of CD11b, actin polymerization and adherence in human neutrophils. J. Immunol. 159:2952-2959.
16. Stamatiou, P., Q. Hamid, Y. Song, W. Yu, and W. S. Powell. 1996. Stimulation of eosinophil recruitment into rat lungs by 5-oxo-ETE. FASEB J. 10:A982. (Abstr.)
17. Powell, W. S. 1983. Separation of unlabeled metabolites of arachidonic acid from their deuterium- and tritium-labeled analogs by argentation high-pressure liquid chromatography. Anal. Biochem. 128:93-103.
18. Böyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood: isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab. Invest. 21(Suppl. 97):77-89.
19. Hansel, T. T., I. J. De Vries, T. Iff, S. Rihs, M. Wandzilak, S. Betz, K. Blaser, and C. Walker. 1991. An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils. J. Immunol. Methods 145:105-110.
20. Howard, T. H., and C. O. Oresajo. 1985. The kinetics of chemotactic peptide-induced change in F-actin content, F-actin distribution, and the shape of neutrophils. J. Cell Biol. 101:1078-1085.
21. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:3440-3450.
22. 1 channels. J. Biol. Chem. 261:11520-11523.
23. Alessi, D. R., A. Cuenda, P. Cohen, D. T. Dudley, and A. R. Saltiel. 1995. PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270:27489-27494.
24. Yano, H., S. Nakanishi, K. Kimura. N. Hanai, Y. Saitoh, Y. Fukui, Y. Nonomura, and Y. Matsuda. 1993. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem. 268:25846-25856.
25. Arcaro, A., and M. P. Wymann. 1993. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-tri-phosphate in neutrophil responses. Biochem. J. 296:297-301.
26. Schwenk, U., and J. M. Schröder. 1995. 5-Oxo-eicosanoids are potent eosinophil chemotactic factors - functional characterization and structural requirements. J. Biol. Chem. 270:15029-15036.
27. O'Flaherty, J. T., M. Kuroki, A. B. Nixon, J. Wijkander, E. Yee, S. L. Lee, P. K. Smitherman, R. L. Wykle, and L. W. Daniel. 1996. 5-Oxo-eicosatetraenoate is a broadly active, eosinophil-selective stimulus for human granulocytes. J. Immunol. 157:336-342.
28. 2. Agents Actions Suppl. 46:65-76.
29. Borgeat, P., and B. Samuelsson. 1979. Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes: formation of a novel dihydroxy-eicosatetraenoic acid. J. Biol. Chem. 254:2643-2646.
30. Albert, D. H., and F. Snyder. 1983. Biosynthesis of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) from 1-alkyl-2-acyl-sn-glycero-3-phosphocholine by rat alveolar macrophages: phospholipase A2 and acetyltransferase activities during phagocytosis and ionophore stimulation. J. Biol. Chem. 258:97-102.
31. 2+-mobilization, and actin reorganization in human eosinophils via a pertussis toxin-sensitive G-protein. J. Invest. Dermatol. 108:108-112.
32. Stossel, T. P. 1994. The E. Donnall Thomas Lecture, 1993: the machinery of blood cell movements. Blood 84:367-379.
33. Kernen, P., M. P. Wymann, V. von Tscharner, D. A. Deranleau, P. C. Tai, C. J. Spry, C. A. Dahinden, and M. Baggiolini. 1991. Shape changes, exocytosis, and cytosolic free calcium changes in stimulated human eosinophils. J. Clin. Invest. 87:2012-2017.
34. Elsner, J., S. Dichmann, G. J. Dobos, and A. Kapp. 1996. Actin polymerization in human eosinophils, unlike human neutrophils, depends on intracellular calcium mobilization. J. Cell. Physiol. 167:548-555.
35. Meshulam, T., P. Proto, R. D. Diamond, and D. A. Melnick. 1986. Calcium modulation and chemotactic response: divergent stimulation of neutrophil chemotaxis and cytosolic calcium response by the chemotactic peptide receptor. J. Immunol. 137:1954-1960.
36. Hendey, B., and F. R. Maxfield. 1993. Regulation of neutrophil motility and adhesion by intracellular calcium transients. Blood Cells 19:143-161 (discussion: 161-164).
37. Ebisawa, M., B. S. Bochner, S. N. Georas, and R. P. Schleimer. 1992. Eosinophil transendothelial migration induced by cytokines. I. Role of endothelial and cosinophil adhesion molecules in IL-1 beta-induced transendothelial migration. J. Immunol. 149:4021-4028.
38. Sriramarao, P., U. H. von Andrian, E. C. Butcher, M. A. Bourdon, and D. H. Broide. 1994. L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo. J. Immunol. 153:4238-4246.
39. Lawrence, M. B., D. F. Bainton, and T. A. Springer. 1994. Neutrophil tethering to and rolling on E-selectin are separable by requirement for L-selectin. Immunity 1:137-145.
40. Henriques, G. M., J. M. Miotla, R. S. B. Cordeiro, B. A. Wolitzky, S. T. Woolley, and P. G. Hellewell. 1996. Selectins mediate eosinophil recruitment in vivo - a comparison with their role in neutrophil influx. Blood 87:5297-5304.
41. Kishimoto, T. K., M. A. Jutila, E. L. Berg, and E. C. Butcher. 1989. Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science 245:1238-1241.
42. Kahn, J., R. H. Ingraham, F. Shirley, G. I. Migaki, and T. K. Kishimoto. 1994. Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin. J. Cell Biol. 125:461-470.
43. Spertini, O., G. S. Kansas, J. M. Munro, J. D. Griffin, and T. F. Tedder. 1991. Regulation of leukocyte migration by activation of the leukocyte adhesion molecule-1 (LAM-1) selectin. Nature 349:691-694.
44. Haribabu, B., D. A. Steeber, H. Ali, R. M. Richardson, R. Snyderman, and T. F. Tedder. 1997. Chemoattractant receptor-induced phosphorylation of L-selectin. J. Biol. Chem. 272:13961-13965.
45. Powell, W. S., R. J. MacLeod, S. Gravel, F. Gravelle, and A. Bhakar. 1996. Metabolism and biologic effects of 5-oxoeicosanoids on human neutrophils. J. Immunol. 156:336-342.
46. 2+ transients, actin reorganization, superoxide-anion production and receptor up-regulation. Eur. J. Biochem. 236:1003-1009.
47. O'Flaherty, J. T., M. Kuroki, A. B. Nixon, J. Wijkander, E. Yee, S. L. Lee, P. K. Smitherman, R. L. Wykle, and L. W. Daniel. 1996. 5-oxo-eicosanoids and hematopoietic cytokines cooperate in stimulating neutrophil function and the mitogen-activated protein kinase pathway. J. Biol. Chem. 271: 17821-17828.
48. 1. J. Muscle Res. Cell Motil. 7:405-412.
49. Zigmond, S. H. 1996. Signal transduction and actin filament organization. Curr. Opin. Cell Biol. 8:66-73.
50. Sham, R. L., P. D. Phatak, T. P. Ihne, C. N. Abboud, and C. H. Packman. 1993. Signal pathway regulation of interleukin-8-induced actin polymerization in neutrophils. Blood 82:2546-2551.
51. Vlahos, C. J., W. F. Matter, R. F. Brown, A. E. Traynor-Kaplan, P. G. Heyworth, E. R. Prossnitz, R. D. Ye, P. Marder, J. A. Schelm, K. J. Rothfuss, B. S. Serlin, and P. J. Simpson. 1995. Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase. J. Immunol. 154:2413-2422.