Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor-α: Phosphorylation of cytosolic phospholipase A2 and transactivation of cyclooxygenase-2

Journal of Neurochemistry

Volumn 73, Issue 4, 1999, Pages 1641-1649

  Hernández, Marita ^a   Bayón, Yolanda ^a   Sánchez Crespo, Mariano ^a   Nieto, María Luisa ^a  

^a UNIVERSITY OF VALLADOLID   (Spain)

Author keywords

Astrocytes; Cyclooxygenase; Cytokines; Mitogen activated protein kinase; Nuclear factor B

Indexed keywords

CYCLOOXYGENASE 2; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2; PROSTANOID; TUMOR NECROSIS FACTOR ALPHA;

ARACHIDONIC ACID METABOLISM; ARTICLE; ASTROCYTOMA CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSACTIVATION;

ARACHIDONIC ACID; ASTROCYTOMA; BRAIN NEOPLASMS; CYCLOOXYGENASE 2; CYTOSOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; KINETICS; MEMBRANE PROTEINS; NF-KAPPA B; PHOSPHOLIPASES A; PHOSPHORYLATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0344979749     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0731641.x     Document Type: Article

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