Paradoxical effects of metalloporphyrins on doxorubicin-induced apoptosis: Scavenging of reactive oxygen species versus induction of heme oxygenase-1

Free Radical Biology and Medicine

Volumn 33, Issue 7, 2002, Pages 988-997

  Konorev, Eugene A ^a   Kotamraju, Srigiridhar ^a   Zhao, Hongtao ^a   Kalivendi, Shasi ^a   Joseph, Joy ^a   Kalyanaraman, B ^a  

^a FREE RADICAL RESEARCH CENTER   (United States)

Author keywords

Apoptosis; Free radicals; Heme oxygenase; Metalloporphyrins; Oxygen radicals; ROS; SOD mimetics

Indexed keywords

COBALT; CYTOCHROME C; DOXORUBICIN; HEME OXYGENASE 1; HYDROGEN PEROXIDE; IRON; MANGANESE; METALLOPORPHYRIN; OXYGEN; REACTIVE OXYGEN METABOLITE; SCAVENGER; SEMIQUINONE; SUPEROXIDE; ZINC;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; ELECTRON SPIN RESONANCE; ENZYME INHIBITION; HEART MUSCLE CELL; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; RAT; SPIN TRAPPING;

ANIMALS; APOPTOSIS; DOXORUBICIN; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; HEART; HEART VENTRICLES; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; KINETICS; MALE; METALLOPORPHYRINS; MUSCLE CELLS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

OXY;

EID: 0036801924     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00989-9     Document Type: Article

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