Spin trap (N-t-butyl-α-phenylnitrone)-mediated suprainduction of heme oxygenase-1 in kidney ischemia/reperfusion model: Role of the oxygenase in protection against oxidative injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 291, Issue 2, 1999, Pages 911-919

  Maines, Mahin D ^a   Raju, Vulapali S ^a   Panahian, Nariman ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILIRUBIN; BILIVERDIN; HEME OXYGENASE; N TERT BUTYL ALPHA PHENYLNITRONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; GENE INDUCTION; IMMUNOCYTOCHEMISTRY; KIDNEY ISCHEMIA; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY;

ANIMALS; ANTIBODIES; BLOTTING, NORTHERN; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; IMMUNOHISTOCHEMISTRY; IRON; ISOENZYMES; KIDNEY; LIPID PEROXIDATION; NITROGEN OXIDES; OXIDATIVE STRESS; OXYGENASES; RATS; REPERFUSION INJURY; RNA, MESSENGER; SPIN TRAPPING; TIME FACTORS;

EID: 0032693947     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Alam J, Shibahara S and Smith A (1989) Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells. J Biol Chem 264:6371-6375.
2. Baker GL, Corry RJ and Autor AP (1985) Oxygen free radical induced damage in kidneys subjected to warm ischemia and reperfusion. Protective effect of superoxide dismutase. Ann Surg 202:628-641.
3. Beckman JS and Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly. Am J Physiol 271:C1424-C1437.
4. Cruse I and Maines MD (1988) Evidence suggesting that the two forms of heme oxygenase are products of different genes. J Biol Chem 263:3348-3353.
5. Dwyer BE, Lu SY, Laitinen JT and Nishimura RN (1998) Protective properties of tin and manganese-centered porphyrins against hydrogen peroxide-mediated injury in rat astroglial cells. J Neurochem 71:2497-2504.
6. Eisenstein RS, Garcia-Mayol D, Pettingell W and Munro HN (1991) Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. Proc Natl Acad Sci USA 88:688-692.
7. Emami A, Schwarty JH and Borkan SC (1991) Transient ischemia or heat stress induces a cytoprotectant protein in rat kidney. Am J Physiol 260:F479-F485.
8. Evans CA (1979) Spin trapping. Aldrichimica Acta 12:23-29.
9. Ewing JF and Maines MD (1991) Rapid induction of heme oxygenase-1 mRNA and protein by hyperthermia in rat brain: Heme oxygenase-2 is not a heat shock protein. Proc Natl Acad Sci USA 88:5364-5368.
10. Floyd RA (1997) Protective action of nitrone-based free radical traps against oxidative damage to the central nervous system. Adv Pharmacol 38:361-532.
11. Goodman AI, Choudhury M, da Silva JL, Schwartzman ML and Abraham NG (1997) Overexpression of the heme oxygenase gene in renal cell carcinoma. Proc Soc Exp Biol Med 214:54-61.
12. 2-resistant fibroblasts. Free Rad Biol Med 20:735-741.
13. Hensley K, Tabatabaie T, Stewart CA, Pye Q and Floyd RA (1997) Nitric oxide and derived species as toxic agents in stroke, AIDS dementia, and chronic neurodegenerative disorders. Chem Res Toxicol 10:527-532.
14. Hill JM and Switzer RC (1984) The regional distribution and cellular localization of iron in the rat brain. Neuroscience 11:595-603.
15. Huang TJ, Trakshel GM and Maines MD (1989): Detection of 10 variants of biliverdin reductase in rat liver by two-dimensional gel electrophoresis. J Biol Chem 264:7844-7849.
16. Keyse SM and Tyrrell RM (1989) Heme oxygenase is the major 32-KDA stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci USA 86:99-103.
17. Kiyama S, Yoshioka T, Burr IM, Kon V, Fogo A and Ichikawa I (1995) Strategic locus for the activation of the superoxide dismutase gene in the nephron. Kidney Intl 47:536-546.
18. Lavrovsky Y, Schwartzman ML and Abraham NG (1993) Novel regulatory sites of the human heme oxygenase-1 promoter region. Biochem Biophys Res Commun 196:336-341.
19. Lipton SA, Single DJ and Stamler JS (1994) Neuroprotective and neurodestructive effects of nitric oxide and redox congeners. Ann NY Acad Sci 738:382-387.
20. Maines MD (1992) in Heme Oxygenase: Clinical Applications and Functions, p 276, CRC Press, Inc., Boca Raton, FL.
21. Maines MD (1997) The heme oxygenase system: A regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37:517-554.
22. Maines MD and Abrahamsson PA (1996) Expression of heme oxygenase-1 (HSP32) in human prostate: Normal, hyperplastic and tumor tissue distribution. Urology 47:727-733.
23. Maines MD, Mayer RD, Ewing JF and McCoubrey WK Jr (1993) Induction of kidney heme oxygenase-1 (HSP32) mRNA and protein by ischemia: Possible role of heme as both promoter of tissue damage and regulator of HSP32. J Pharmacol Exp Ther 264:457-462.
24. Maines MD, Trakshel GM and Kutty RK (1986) Characterization of two constitutive forms of rat liver microsomal heme oxygenase: Only one molecular species of the enzyme is inducible. J Biol Chem 261:411-419.
25. Marks GS, Brien JF, Nakakatsa K and McLaughlin BE (1991) Does carbon monoxide have a physiological function? Trends Pharmacol Sci 12:185-188.
26. McCoubrey WK, Huang TJ and Maines MD (1997) Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem 247:725-732.
27. Motterlini R, Gonzales A, Foresti R, Clark JE, Green CJ and Winslow RM (1998) Heme oxygenase-1-derived carbon monoxide contributes to the suppression of acute hypertensive responses in vivo. Circ Res 83:568-577.
28. Pedraza-Chaverri J, Tapia E and Bobadilla N (1992) Ischemia-reperfusion induced acute renal failure in the rat is ameliorated by the spin-trapping agent α-phenyl-N-tert.-butylnitrone (PBN). Renal Failure 14:467-471.
29. Phillis JW (1997) Free radical scavenger and spin traps, in Primer on Cerebrovascular Diseases (Welch KM et al. eds) pp 261-265, Academic Press, Inc., Orlando, FL.
30. Pompella A, Maellaro E, Casini AF and Comporti M (1987) Histochemical detection of lipid peroxidation in the liver of bromobenzine-poisoned mice. Am J Pathol 129:295-301.
31. Ponka P, Beaumont C and Richardson DR (1998) Function and regulation of transferrin and ferritin. Semin Hematol 35:35-54.
32. Poss KD and Tonegawa S (1997) Reduced stress defense in heme oxygenase-1 deficient cells. Proc Natl Acad Sci USA 94:10925-10930.
33. Raju VS and Maines MD (1996) Renal ischemia/reperfusion up-regulates heme oxygenase-1 (HSP32) expression and increases cGMP in rat heart. J Pharmacol Exp Ther 277:1814-1822.
34. Raju VS, McCoubrey WK Jr and Maines MD (1997) Regulation of heme oxygenase-2 mRNA and protein by glucocorticoids: Characterization of a functional GRE. Biochim Biophys Acta 1351:89-104.
35. Rotenberg MO and Maines MD (1990) Isolation, characterization, and expression of Escherichia coli of a cDNA encoding rat heme oxygenase-2. J Biol Chem 265:7501-7506.
36. Sen S and Phillis JW (1993) Alpha-phenyl-tert.-butylnitrone (PBN) attenuates hydroxyl radical production during ischemia-reperfusion injury of rat brain: An EPR study. Free Rad Res Commun 19:255-265.
37. Shibahara S, Muller R, Taguchi H and Yoshida T (1985) Cloning and expression of cDNA for rat heme oxygenase. Proc Natl Acad Sci USA 82:7865-7869.
38. Shibahara S, Muller R, Taguchi H and Yoshida T (1987) Transcriptional control of rat heme oxygenase by heat shock. J Biol Chem 262:12889-12892.
39. Smith MA, Richey PL, Kutty RK, Wiggert B and Perry G (1995) Ultrastructural localization of heme oxygenase-1 to the neurofibrillary pathology for Alzheimer disease. Mol Chem Neuropath 24:227-230.
40. Snyder SH, Jaffrey SR and Zakhary R (1998) Nitric oxide and carbon monoxide: Parallel roles as neural messengers. Brain Res Brain Res Rev 26:167-175.
41. Stocker R, Yamamoto Y, McDonagh AF, Glazer AN and Ames BN (1987) Bilirubin is an antioxidant of possible physiological importance. Science (Wash DC) 235:1043-1047.
42. Stuehr DJ (1997) Structure-function aspects in the nitric oxide synthases. Ann Rev Pharmacol Toxicol 37:339-359.
43. Suematsu M, Kashiwagi S, Sano T, Goda N, Shinoda Y and Ishimura Y (1994) Carbon monoxide as an endogenous modulator of hepatic vascular perfusion. Biochem Biophys Res Commun 205:133-1337.
44. Sun Y, Rotenberg MO and Maines MD (1990) Developmental expression of heme oxygenase isozymes in rat brain: Two mRNAs are detected. J Biol Chem 265:8212-8217.
45. Terzi F, Maunoury R, Colucci-Guyon E, Babinet C, Federici P, Briand P and Friedlander G (1997) Normal tubular regeneration and differentiation of the postischemic kidney in mice lacking vimentin. Am J Pathol 150:1361-1371.
46. Weber CM, Eke BC and Maines MD (1994) Corticosterone regulates heme oxygenase-2 and NO synthase transcription and protein expression in rat brain. J Neurochem 63:953-962.
47. Witzgall R, O'Leary E, Gessner R, Guellelte AJ and Bonrentre JV (1993) Kid-1, a putative renal transcription factor: Regulation during ontogeny and in response to ischemia and toxic injury. Mol Cell Biol 13:1933-1942.
48. Woo J, Iyer S, Conrejo M-C, Mori N, Gao L, Maines MD and Buelow R (1998) Stress protein induced immunosuppression: Inhibition of cellular immune effector functions following overexpression of heme oxygenase-1 (hsp 32). Transplant Immun 6:84-93.