Acid Sphingomyelinase-deficient Macrophages Have Defective Cholesterol Trafficking and Efflux

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 44976-44983

  Leventhal, Andrew R ^a   Chen, Wengen ^a   Tall, Alan R ^a   Tabas, Ira ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; CHOLESTEROL; ESTERIFICATION; HYDROLYSIS;

INTRACELLULAR SITES;

ENZYMES;

CHOLESTEROL; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; FILIPIN; HIGH DENSITY LIPOPROTEIN; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; 25 HYDROXYCHOLESTEROL; 25-HYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE; LIPOSOME; LOW DENSITY LIPOPROTEIN;

ANIMAL CELL; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CELL MEMBRANE; CHOLESTEROL TRANSPORT; ENDOSOME; ENZYME DEFICIENCY; FLUORESCENCE; FOAM CELL; HYDROLYSIS; KNOCKOUT MOUSE; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; FLUORESCENCE MICROSCOPY; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; RISK FACTOR; TIME; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA;

ANIMAL; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CHOLESTEROL; ENDOSOMES; HYDROXYCHOLESTEROLS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIPOSOMES; LYSOSOMES; MACROPHAGES; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; RISK FACTORS; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0035976969     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106455200     Document Type: Article

References (57)

1. Ross, R. (1995) Annu. Rev. Physiol. 57, 791-804
2. Libby, P., and Clinton, S. K. (1993) Curr. Opin. Lipidol. 4, 355-363
3. Tabas, I. (2000) Biochim. Biophys. Acta 1529, 164-174
4. Williams, K. J., and Tabas, I. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 551-561
5. Brown, M. S., and Goldstein, J. L. (1983) Annu. Rev. Biochem. 52, 223-261
6. Tall, A. R. (1998) Eur. Heart J. 19, A31-A35
7. Wang, N., Silver, D. L., Thiele, C., and Tall, A. R. (2001) J. Biol. Chem. 276, 23742-23747
8. Fielding, P. E., Nagao, K., Hakamata, H., Chimini, G., and Fielding, C. J. (2000) Biochemistry 39, 14113-14120
9. Ji, Y., Jian, B., Wang, N., Sun, Y., Moya, M. L., Phillips, M. C., Rothblat, G. H., Swaney, J. B., and Tall, A. R. (1997) J. Biol. Chem. 272, 20982-20985
10. Rothblat, G. H., Llera-Moya, M., Atger, V., Kellner-Weibel, G., Williams, D. L., and Phillips, M. C. (1999) J. Lipid Res. 40, 781-796
11. Liscum, L., and Klansek, J. J. (1998) Curr. Opin. Lipidol. 9, 131-135
12. Blanchette-Mackie, E. J. (2000) Biochim. Biophys. Acta 1486, 171-183
13. Ory, D. S. (2000) Biochim. Biophys. Acta 1529, 331-339
14. Naureckiene, S., Sleat, D. E., Lackland, H., Fensom, A., Vanier, M. T., Wattiaux, R., Jadot, M., and Lobel, P. (2000) Science 290, 2298-2301
15. Kobayashi, T., Beuchat, M. H., Lindsay, M., Frias, S., Palmiter, R. D., Sakuraba, H., Parton, R. G., and Gruenberg, J. (1999) Nat. Cell Biol. 1, 113-118
16. Schuchman, E. H., and Desnick, R. J. (1995) in The Metabolic and Molecular Basis of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., eds) pp. 2601-2624, McGraw-Hill, New York
17. Slotte, J. P. (1999) Chem. Phys. Lipids 102, 13-27
18. Ridgway, N. D. (2000) Biochim. Biophys. Acta 1484, 129-141
19. Viana, M. B., Giugliani, R., Leite, V. H., Barth, M. L., Lekhwani, C., Slade, C. M., and Fensom, A. (1990) J. Med. Genet. 27, 499-504
20. Worgall, T. S., McGovern, M. M., Jiang, X. C., Berglund, L., Shea, S., Tabas, I., and Deckelbaum, R. J. (2001) Circulation 102, 11-30
21. Tall, A. R., and Wang, N. (2000) J. Clin. Invest. 106, 1205-1207
22. Horinouchi, K., Erlich, S., Perl, D., Ferlinz, K., Bisgaier, C. L., Sandhoff, K., Desnick, R. J., Stewart, C. L., and Schuchman, E. H. (1995) Nature Gen. 10, 288-293
23. Otterbach, B., and Stoffel, W. (1995) Cell 81, 1053-1061
24. Tang, W., Walsh, A., and Tabas, I. (1999) Biochim. Biophys. Acta 1437, 301-316
25. Havel, R. J., Eder, H., and Bragdon, J. (1955) J. Clin. Invest. 34, 1345-1353
26. Basu, S. K., Goldstein, J. L., Anderson, R. G. W., and Brown, M. S. (1976) Proc. Natl. Acad. Sci. U. S. A. 73, 3178-3182
27. Rinninger, F., Brundert, M., Jackle, S., Kaiser, T., and Greten, H. (1995) Biochim. Biophys. Acta 1255, 141-153
28. Tabas, I., Boykow, G. C., and Tall, A. R. (1987) J. Clin. Invest. 79, 418-426
29. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
30. Tabas, I., Marathe, S., Keesler, G. A., Beatini, N., and Shiratori, Y. (1996) J. Biol. Chem. 271, 22773-22781
31. Blanchette-Mackie, E. J., Dwyer, N. K., Amende, L. M., Kruth, H. S., Butler, J. D., Sokol, J., Comly, M. E., Vanier, M. T., August, J. T., Brady, R. O., and Pentchev, P. G. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 8022-8026
32. Tabas, I., Lim, S., Xu, X., and Maxfield, F. R. (1990) J. Cell Biol. 111, 929-940
33. Wang, N., Silver, D. L., Costet, P., and Tall, A. R. (2000) J. Biol. Chem. 275, 33053-33058
34. Lange, Y., Ye, J., Rigney, M., and Steck, T. L. (2000) J. Biol. Chem. 275, 17468-17475
35. Mukherjee, S., Zha, X., Tabas, I., and Maxfield, F. R. (1998) Biophys. J. 75, 1915-1925
36. Tabas, I., Rosoff, W. J., and Boykow, G. C. (1988) J. Biol. Chem. 263, 1266-1272
37. Xu, X., and Tabas, I. (1991) J. Biol. Chem. 266, 17040-17048
38. Botelho, R. J., Hackam, D. J., Schreiber, A. D., and Grinstein, S. (2000) J. Biol. Chem. 275, 15717-15727
39. Nishikawa, K., Arai, H., and Inoue, K. (1990) J. Biol. Chem. 265, 5226-5231
40. Fadok, V. A., Bratton, D. L., Rose, D. M., Pearson, A., Ezekewitz, R. A., and Henson, P. M. (2000) Nature 405, 85-90
41. Levade, T., Salvayre, R., Maret, A., and Douste-Blazy, L. (1988) J. Inherit. Metab. Dis. 11, 151-157
42. Maor, I., Mandel, H., and Aviram, M. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 1378-1387
43. Liscum, L., Ruggiero, R. M., and Faust, J. R. (1989) J. Cell Biol. 108, 1625-1636
44. Pentchev, P. G., Comly, M. E., Kruth, H. S., Vanier, M. T., Wenger, D. A., Patel, S., and Brady, R. O. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 8247-8251
45. Cruz, J. C., Sugii, S., Yu, C., and Chang, T. Y. (2000) J. Biol. Chem. 275, 4013-4021
46. Puri, V., Watanabe, R., Dominguez, M., Sun, X., Wheatley, C. L., Marks, D. L., and Pagano, R. E. (1999) Nat. Cell Biol. 1, 386-388
47. Zhang, M., Dwyer, N. K., Neufeld, E. B., Love, D. C., Cooney, A., Comly, M., Patel, S., Watari, H., Strauss, J. F., III, Pentchev, P. G., Hanover, J. A., and Blanchette-Mackie, E. J. (2001) J. Biol. Chem. 276, 3417-3425
48. Zhang, M., Dwyer, N. K., Love, D. C., Cooney, A., Comly, M., Neufeld, E., Pentchev, P. G., Blanchette-Mackie, E. J., and Hanover, J. A. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 4466-4471
49. Chen, W., Sun, Y., Welch, C., Gorelik, A., Leventhal, A. R., Tabas, I., and Tall, A. R. (2001) J. Biol. Chem. 276, 43564-43569
50. Reagan, J. W., Jr., Hubbert, M. L., and Shelness, G. S. (2000) J. Biol. Chem. 275, 38104-38110
51. Lundberg, B. (1985) Atherosclerosis 56, 93-110
52. Small, D. M., Bond, M. G., Waugh, D., Prack, M., and Sawyer, J. K. (1984) J. Clin. Invest. 73, 1590-1605
53. Rapp, J. H., Connor, W. E., Lin, D. S., Inahara, T., and Porter, J. M. (1983) J. Lipid Res. 24, 1329-1335
54. Shio, H., Haley, N. J., and Fowler, S. (1979) Lab. Invest. 41, 160-167
55. Tangirala, R. K., Mahlberg, F. H., Glick, J. M., Jerome, W. G., and Rothblat, G. H. (1993) J. Biol. Chem. 268, 9653-9660
56. Jiang, X. C., Paultre, F., Pearson, T. A., Reed, R. G., Francis, C. K., Lin, M., Berglund, L., and Tall, A. R. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 2614-2618
57. Tabas, I. (1999) Chem. Phys. Lipids 102, 131-139