Regulation and Activity of the Human ABCA1 Gene in Transgenic Mice

Journal of Biological Chemistry

Volumn 276, Issue 21, 2001, Pages 18046-18051

  Cavelier, Lucia B ^b   Qiu, Yang ^b   Bielicki, John K ^b   Afzal, Veena ^b   Cheng, Jan Fang ^a   Rubin, Edward M ^a  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CHOLESTEROL; DNA; GENETIC ENGINEERING; PROTEINS; RNA; TISSUE CULTURE;

MACROPHAGES;

BIOCHEMISTRY;

ABC TRANSPORTER; ABC TRANSPORTER A1; APOLIPOPROTEIN A1; COMPLEMENTARY DNA; GENE PRODUCT; HIGH DENSITY LIPOPROTEIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL TRANSPORT; EXON; GENE ACTIVITY; GENE AMPLIFICATION; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; TRANSGENIC MOUSE; ALTERNATIVE RNA SPLICING; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE;

ANIMALIA; EUKARYOTA; MUS MUSCULUS;

ALTERNATIVE SPLICING; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS);

EID: 0035947686     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100565200     Document Type: Article

References (41)

1. Glomset, J. A. (1968) J. Lipid Res. 9, 155-167
2. Fielding, C. J., and Fielding, P. E. (1995) J. Lipid Res. 36, 211-228
3. Oram, J. F., and Yokoyama, S. (1996) J. Lipid Res. 37, 2473-2491
4. Mendez, A. J. (1997) J. Lipid Res. 38, 1807-1821
5. von Eckardstein, A., Chirazi, A., Schuler-Luttmann, S., Walter, M., Kastelein, J. J., Geisel, J., Real, J. T., Miccoli, R., Noseda, G., Hobbel, G., and Assmann, G. (1998) J. Lipid Res. 39, 987-998
6. Francis, G. A., Knopp, R. H., and Oram, J. F. (1995) J. Clin. Invest. 96, 78-87
7. Remaley, A. T., Schumacher, U. K., Stonik, J. A., Farsi, B. D., Nazih, H., and Brewer, H. B., Jr. (1997) Arterioscler. Thromb. Vasc. Biol. 17, 1813-1821
8. Assman, G., von Eckardstein, A., and Brewer, H. B. (1995) in The Metabolic Bases of Inherited Disease (Scriver, C. R., Beaudet, A. L., Sly, W. S., and Valle, D., eds) pp. 2053-2072, McGraw-Hill Inc., New York
9. Serfaty-Lacrosniere, C., Civeira, F., Lanzberg, A., Isaia, P., Berg, J., Janus, E. D., Smith, M. P., Jr., Pritchard, P. H., Frohlich, J., Lees, R. S., Barnard, G. F., Ordovas, J. M., and Schaefer, E. J. (1994) Atherosclerosis 107, 85-98
10. Lawn, R. M., Wade, D. P., Garvin, M. R., Wang, X., Schwartz, K., Porter, J. G., Seilhamer, J. J., Vaughan, A. M., and Oram, J. F. (1999) J. Clin. Invest. 104, R25-R31
11. Clee, S. M., Kastelein, J. J., van Dam, M., Marcil, M., Roomp, K., Zwarts, K. Y., Collins, J. A., Roelants, R., Tamasawa, N., Stulc, T., Suda, T., Ceska, R., Boucher, B., Rondeau, C., DeSouich, C., Brooks-Wilson, A., Molhuizen, H. O., Frohlich, J., Genest, J., Jr., and Hayden, M. R. (2000) J. Clin. Invest. 106, 1263-1270
12. Remaley, A. T., Rust, S., Rosier, M., Knapper, C., Naudin, L., Broccardo, C., Peterson, K. M., Koch, C., Arnould, I., Prades, C., Duverger, N., Funke, H., Assman, G., Dinger, M., Dean, M., Chimini, G., Santamarina-Fojo, S., Fredrickson, D. S., Denefle, P., and Brewer, H. B., Jr. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 12685-12690
13. Rust, S., Rosier, M., Funke, H., Real, J., Amoura, Z., Piette, J. C., Deleuze, J. F., Brewer, H. B., Duverger, N., Denefle, P., and Assmann, G. (1999) Nat. Genet. 22, 352-355
14. Bodzioch, M., Orso, E., Klucken, J., Langmann, T., Bottcher, A., Diederich, W., Drobnik, W., Barlage, S., Buchler, C., Porsch-Ozcurumez, M., Kaminski, W. E., Hahmann, H. W., Oette, K., Rothe, G., Aslanidis, C., Lackner, K. J., and Schmitz, G. (1999) Nat. Genet. 22, 347-351
15. Brooks-Wilson, A., Marcil, M., Clee, S. M., Zhang, L. H., Roomp, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O., Loubser, O., Ouelette, B. F., Fichter, K., Ashbourne-Excoffon, K. J., Sensen, C. W., Scherer, S., Mott, S., Denis, M., Martindale, D., Frohlich, J., Morgan, K., Koop, B., Pimstone, S., Kastelein, J. J., Hayden, M. R., (1999) Nat. Genet. 22, 336-345
16. Langmann, T., Klucken, J., Reil, M., Liebisch, G., Luciani, M. F., Chimini, G., Kaminski, W. E., and Schmitz, G. (1999) Biochem. Biophys. Res. Commun. 257, 29-33
17. Bortnick, A. E., Rothblat, G. H., Stoudt, G., Hoppe, K. L., Royer, L. J., McNeish, J., and Francone, O. L. (2000) J. Biol. Chem. 275, 28634-28640
18. Oram, J. F., Lawn, R. M., Garvin, M. R., and Wade, D. P. (2000) J. Biol. Chem. 275, 34508-34511
19. Repa, J. J., Turley, S. D., Lobaccaro, J. A., Medina, J., Li, L., Lustig, K., Shan, B., Heyman, R. A., Dietschy, J. M., and Mangelsdorf, D. J. (2000) Science 289, 1524-1529
20. Santamarina-Fojo, S., Peterson, K., Knapper, C., Qiu, Y., Freeman, L., Cheng, J. F., Osorio, J., Remaley, A., Yang, X. P., Haudenschild, C., Prades, C., Chimini, G., Blackmon, E., Francois, T., Duverger, N., Rubin, E. M., Rosier, M., Denefle, P., Fredrickson, D. S., and Brewer, H. B., Jr. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 7987-7992
21. Costet, P., Luo, Y., Wang, N., and Tall, A. R. (2000) J. Biol. Chem. 275, 28240-28245
22. Schwartz, K., Lawn, R. M., and Wade, D. P. (2000) Biochem. Biophys. Res. Commun. 274, 794-802
23. Venkateswaran, A., Laffitte, B. A., Joseph, S. B., Mak, P. A., Wilpitz, D. C., Edwards, P. A., and Tontonoz, P. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 12097-12102
24. Brousseau, M. E., Eberhart, G. P., Dupuis, J., Asztalos, B. F., Goldkamp, A. L., Schaefer, E. J., and Freeman, M. W. (2000) J. Lipid Res. 41, 1125-1135
25. Christiansen-Weber, T. A., Voland, J. R., Wu, Y., Ngo, K., Roland, B. L., Nguyen, S., Peterson, P. A., and Fung-Leung, W. P. (2000) Am. J. Pathol. 157, 1017-1029
26. McNeish, J., Aiello, R. J., Guyot, D., Turi, T., Gabel, C., Aldinger, C., Hoppe, K. L., Roach, M. L., Royer, L. J., de Wet, J., Broccardo, C., Chimini, G., and Francone, O. L. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4245-4250
27. Orso, E., Broccardo, C., Kaminski, W. E., Bottcher, A., Liebisch, G., Drobnik, W., Gotz, A., Chambenoit, O., Diederich, W., Langmann, T., Spruss, T., Luciani, M. F., Rothe, G., Lackner, K. J., Chimini, G., and Schmitz, G. (2000) Nat. Genet. 24, 192-196
28. Qiu, Y., Cavelier, L., Chiu, S., Rubin, E. M., and Cheng, J.-F. (2001) Genomics, in press
29. Ueda, Y., Royer, L., Gong, E., Zhang, J., Cooper, P. N., Francone, O., and Rubin, E. M. (1999) J. Biol. Chem. 274, 7165-7171
30. Abe-Dohmae, S., Suzuki, S., Wada, Y., Aburatani, H., Vance, D. E., and Yokoyama, S. (2000) Biochemistry 39, 11092-11099
31. Heinemeyer, T., Chen, X., Karas, H., Kel, A. E., Kel, O. V., Liebich, I., Meinhardt, T., Reuter, I., Schacherer, F., and Wingender, E. (1999) Nucleic Acids Res. 27, 318-322
32. Schoonjans, K., Brendel, C., Mangelsdorf, D., and Auwerx, J. (2000) Biochim. Biophys. Acta 1529, 114-125
33. Repa, J. J., and Mangelsdorf, D. J. (2000) Annu. Rev. Cell Dev. Biol. 16, 459-481
34. Lu, T. T., Makishima, M., Repa, J. J., Schoonjans, K., Kerr, T. A., Auwerx, J., and Mangelsdorf, D. J. (2000) Mol. Cell 6, 507-515
35. Goodwin, B., Jones, S. A., Price, R. R., Watson, M. A., McKee, D. D., Moore, L. B., Galardi, C., Wilson, J. G., Lewis, M. C., Roth, M. E., Maloney, P. R., Willson, T. M., and Kliewer, S. A. (2000) Mol. Cell 6, 517-526
36. Nitta, M., Ku, S., Brown, C., Okamoto, A. Y., and Shan, B. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 6660-6665
37. Lala, D., Syka, P., Lazrchik, S., Mangelsdorf, D., Parker, K., and Heyman, R. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4895-4900
38. von Eckardstein, A., and Assmann, G. (2000) Curr. Opin. Lipidol. 11, 627-637
39. Broccardo, C., Luciani, M., and Chimini, G. (1999) Biochim. Biophys. Acta 1461, 395-404
40. Hamon, Y., Luciani, M. F., Becq, F., Verrier, B., Rubartelli, A., and Chimini, G. (1997) Blood 90, 2911-2915
41. Hamon, Y., Broccardo, C., Chambenoit, O., Luciani, M. F., Toti, F., Chaslin, S., Freyssinet, J. M., Devaux, P. F., McNeish, J., Marguet, D., and Chimini, G. (2000) Nat. Cell Biol. 2, 399-406