Membrane topology of the ATP binding cassette transporter ABCR and its relationship to ABC1 and related ABCA transporters: Identification of N-linked glycosylation sites

Journal of Biological Chemistry

Volumn 276, Issue 26, 2001, Pages 23539-23546

  Bungert, Stefanie ^a   Molday, Laurie L ^a   Molday, Robert S ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINETRIPHOSPHATE; AMINO ACIDS; CELL MEMBRANES; CHEMICAL BONDS; DISEASES; ENZYMES; POLYPEPTIDES;

MEMBRANE TOPOLOGY;

BIOCHEMISTRY;

ABC TRANSPORTER; ABC1 TRANSPORTER; ABCA TRANSPORTER; AMINO ACID; POLYPEPTIDE; UNCLASSIFIED DRUG; ABC TRANSPORTER A1; ABCA4 PROTEIN, HUMAN; CONCANAVALIN A; DISULFIDE; GLYCOPROTEIN; TRYPSIN;

ANIMAL TISSUE; ARTICLE; CATTLE; GENETIC TRANSFECTION; GLYCOSYLATION; HUMAN; HUMAN TISSUE; MEMBRANE STRUCTURE; MEMBRANE TRANSPORT; NONHUMAN; PHOTOAFFINITY LABELING; PHOTORECEPTOR; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RETINA ROD OUTER SEGMENT; SITE DIRECTED MUTAGENESIS; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CELL STRAIN COS1; CHEMISTRY; CONSENSUS SEQUENCE; GENE DELETION; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY;

ANIMALIA; BOS TAURUS;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CATTLE; CONCANAVALIN A; CONSENSUS SEQUENCE; COS CELLS; DISULFIDES; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; ROD OUTER SEGMENTS; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; TRANSFECTION; TRYPSIN;

EID: 0035968213     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M101902200     Document Type: Article

References (41)

1. Illing, M., Molday, L. L., and Molday, R. S. (1997) J. Biol. Chem. 272, 10303-10310
2. Allikmets, R., Singh, N., Sun, H., Shroyer, N. F., Hutchinson, A., Chidambaram, A., Gerrard, B., Baird, L., Stauffer, D., Peiffer, A., Rattner, A., Smallwood, P., Li, Y., Anderson, K. L., Lewis, R. A., Nathans, J., Leppert, M., Dean, M., and Lupski, J. R. (1997) Nat. Genet. 15, 236-246
3. Azarian, S. M., and Travis, G. H. (1997) FEBS Lett. 409, 247-252
4. Papermaster, D. S., Schneider, B. G., Zorn, M. A., and Kraehenbuhl, J. P. (1978) J. Cell Biol. 78, 415-425
5. Sun, H., and Nathans, J. (1997) Nat. Genet. 17, 15-16
6. Molday, L. L., Rabin, A. R., and Molday, R. S. (2000) Nat. Genet. 25, 257-258
7. Sun, H., Molday, R. S., and Nathans, J. (1999) J. Biol. Chem. 274, 8269-8281
8. Weng, J., Mata, N. L., Azarian, S. M., Tzekov, R. T., Birch, D. G., and Travis, G. H. (1999) Cell 98, 13-23
9. Ahn, J., Wong, J. T., and Molday, R. S. (2000) J. Biol. Chem. 275, 20399-20405
10. Nasonkin, I., Illing, M., Koehler, M. R., Schmid, M., Molday, R. S., and Weber, B. H. (1998) Hum. Genet. 102, 21-26
11. Rozet, J. M., Gerber, S., Souied, E., Perrault, I., Chatelin, S., Ghazi, I., Leowski, C., Dufier, J. L., Munnich, A., and Kaplan, J. (1998) Eur. J. Hum. Genet. 6, 291-295
12. Fishman, G. A., Stone, E. M., Grover, S., Derlacki, D. J., Haines, H. L., and Hockey, R. R. (1999) Arch. Ophthalmol. 117, 504-510
13. Lewis, R. A., Shroyer, N. F., Singh, N., Allikmets, R., Hutchinson, A., Li, Y., Lupski, J. R., Leppert, M., and Dean, M. (1999) Am. J. Hum. Genet. 64, 422-434
14. Souied, E. H., Ducroq, D., Rozet, J. M., Gerber, S., Perrault, I., Sterkers, M., Benhamou, N., Munnich, A., Coscas, G., Soubrane, G., and Kaplan, J. (1999) Invest. Ophthalmol. Vis. Sci. 40, 2740-2744
15. Cremers, F. P., van de Pol, D. J., van Driel, M., den Hollander, A. I., van Haren, F. J., Knoers, N. V., Tijmes, N., Bergen, A. A., Rohrschneider, K., Blankenagel, A., Pinckers, A. J., Deutman, A. F., and Hoyng, C. B. (1998) Hum. Mol. Genet. 7, 355-362
16. Martinez-Mir, A., Paloma, E., Allikmets, R., Ayuso, C., del Rio, T., Dean, M., Vilageliu, L., Gonzalez-Duarte, R., and Balcells, S. (1998) Nat. Genet. 18, 11-12
17. Klevering, B. J., van Driel, M., van de Pol, D. J., Pinckers, A. J., Cremers, F. P., and Hoyng, C. B. (1999) Br. J. Ophthalmol. 83, 914-918
18. Allikmets, R., Shroyer, N. F., Singh, N., Seddon, J. M., Lewis, R. A., Bernstein, P. S., Peiffer, A., Zabriskie, N. A., Li, Y., Hutchinson, A., Dean, M., Lupski, J. R., and Leppert, M. (1997) Science 277, 1805-1807
19. Stone, E. M., Webster, A. R., Vandenburgh, K., Streb, L. M., Hockey, R. R., Lotery, A. J., and Sheffield, V. C. (1998) Nat. Genet. 20, 328-329
20. Broceardo, C., Luciani, M., and Chimini, G. (1999) Biochim. Biophys. Acta 1461, 395-404
21. Luciani, M. F., Denizot, F., Savary, S., Mattei, M. G., and Chimini, G. (1994) Genomics 21, 150-159
22. Zhao, L. X., Zhou, C. J., Tanaka, A., Nakata, M., Hirabayashi, T., Amachi, T., Shioda, S., Ueda, K., and Inagaki, N. (2000) Biochem. J. 350 Pt 3, 865-872
23. Klugbauer, N., and Hofmann, F. (1996) FEBS Lett. 391, 61-65
24. Pullinger, C. R., Hakamata, H., Duchateau, P. N., Eng, C., Aouizerat, B. E., Cho, M. H., Fielding, C. J., and Kane, J. P. (2000) Biochem. Biophys. Res. Commun. 271, 451-455
25. Brooks-Wilson, A., Mareil, M., Clee, S. M., Zhang, L. H., Roomp, K., van Dam, M., Yu, L., Brewer, C., Collins, J. A., Molhuizen, H. O., Loubser, O., Ouelette, B. F., Fichter, K., Ashbourne-Excoffon, K. J., Sensen, C. W., Scherer, S., Mott, S., Denis, M., Martindale, D., Frohlich, J., Morgan, K., Koop, B., Pimstone, S., Kastelein, J. J., Hayden, M. R., and et al. (1999) Nat. Genet. 22, 336-345
26. Bodzioch, M., Orso, E., Klucken, J., Langmann, T., Bottcher, A., Diederich, W., Drobnik, W., Barlage, S., Buchler, C., Porsch-Ozcurumez, M., Kaminski, W. E., Hahmann, H. W., Oette, K., Rothe, G., Aslanidis, C., Lackner, K. J., and Schmitz, G. (1999) Nat. Genet. 22, 347-351
27. Sun, H., Smallwood, P. M., and Nathans, J. (2000) Nat. Genet. 26, 242-246
28. Fitzgerald, M. L., Mendez, A. J., Moore, K. H., Andersson, L. P., Panjeton, H. A., and Freeman, M. W. (2001) J. Biol. Chem. 276, 15137-15145
29. Molday, R. S., and Molday, L. L. (1987) J. Cell Biol. 105, 2589-2601
30. Loewen, C. J., and Molday, R. S. (2000) J. Biol. Chem. 275, 5370-5378
31. Chen, C., and Okayama, H. (1987) Mol. Cell. Biol. 7, 2745-2752
32. Molday, R. S., and Molday, L. L. (1979) J. Biol. Chem. 254, 4653-4660
33. Gafvelin, G., Sakaguchi, M., Andersson, H., and von Heijne, G. (1997) J. Biol. Chem. 272, 6119-6127
34. Loo, T. W., and Clarke, D. M. (1999) Biochemistry 38, 5124-5129
35. Kast, C., Canfield, V., Levenson, R., and Gros, P. (1996) J. Biol. Chem. 271, 9240-9248
36. Loo, T. W., and Clarke, D. M. (1995) J. Biol. Chem. 270, 843-848
37. Schinkel, A. H., Kemp, S., Dolle, M., Rudenko, G., and Wagenaar, E. (1993) J. Biol. Chem. 268, 7474-7481
38. Webster, A. R., Heon, E., Lotery, A. J., Vandenburgh, K., Casavant, T. L., Oh, K. T., Beck, G., Fishman, G. A., Lam, B. L., Levin, A., Heckenlively, J. R., Jacobson, S. G., Weleber, R. G., Sheffield, V. C., and Stone, E. M. (2001) Invest. Ophthalmol. Vis. Sci. 42, 1179-1189
39. Maugeri, A., van Driel, M. A., van de Pol, D. J., Klevering, B. J., van Haren, F. J., Tijmes, N., Bergen, A. A., Rohrschneider, K., Blankenagel, A., Pinckers, A. J., Dahl, N., Brunner, H. G., Deutman, A. F., Hoyng, C. B., and Cremers, F. P. (1999) Am. J. Hum. Genet. 64, 1024-1035
40. Souied, E. H., Ducroq, D., Gerber, S., Ghazi, I., Rozet, J. M., Perrault, I., Munnich, A., Dufier, J. L., Coscas, G., Soubrane, G., and Kaplan, J. (1999) Am. J. Ophthalmol. 128, 173-178
41. Goldberg, A. F., Loewen, C. J., and Molday, R. S. (1998) Biochemistry 37, 680-685